Axoneme Gene Set

Dataset COMPARTMENTS Curated Protein Localization Evidence Scores 2025
Category structural or functional annotations
Type cellular component
Description The bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements. (Gene Ontology, GO_0005930)
External Link http://amigo.geneontology.org/amigo/term/GO:0005930
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Genes

145 proteins localized to the Axoneme cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.

Symbol Name Standardized Value
AKAP14 A kinase (PRKA) anchor protein 14 5.0
DNAAF1 dynein, axonemal, assembly factor 1 5.0
SPAG8 sperm associated antigen 8 5.0
CEP162 centrosomal protein 162kDa 5.0
TOGARAM1 TOG array regulator of axonemal microtubules 1 5.0
DNAH9 dynein, axonemal, heavy chain 9 5.0
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa 5.0
SPACA9 sperm acrosome associated 9 5.0
CFAP77 cilia and flagella associated protein 77 5.0
CFAP210 cilia and flagella associated protein 210 5.0
CCSAP centriole, cilia and spindle-associated protein 5.0
CFAP53 cilia and flagella associated protein 53 5.0
DNAH3 dynein, axonemal, heavy chain 3 5.0
ENKUR enkurin, TRPC channel interacting protein 5.0
EFHB EF-hand domain family, member B 5.0
SAXO1 stabilizer of axonemal microtubules 1 5.0
NME7 NME/NM23 family member 7 5.0
TUBB4A tubulin, beta 4A class IVa 5.0
TUBB4B tubulin, beta 4B class IVb 5.0
CCDC146 coiled-coil domain containing 146 5.0
CFAP20 cilia and flagella associated protein 20 5.0
DNALI1 dynein, axonemal, light intermediate chain 1 5.0
MNS1 meiosis-specific nuclear structural 1 5.0
SSNA1 Sjogren syndrome nuclear autoantigen 1 5.0
EFHC2 EF-hand domain (C-terminal) containing 2 5.0
CIMIP2B ciliary microtubule inner protein 2B 5.0
TUBA1A tubulin, alpha 1a 5.0
CFAP126 cilia and flagella associated protein 126 5.0
SPATA7 spermatogenesis associated 7 5.0
TEKT4 tektin 4 5.0
RIBC2 RIB43A domain with coiled-coils 2 5.0
CIMIP2C ciliary microtubule inner protein 2C 5.0
TEKT2 tektin 2 (testicular) 5.0
DRC3 dynein regulatory complex subunit 3 5.0
TEKT3 tektin 3 5.0
DCDC2 doublecortin domain containing 2 5.0
TEKT1 tektin 1 5.0
CFAP161 cilia and flagella associated protein 161 5.0
DNAH17 dynein, axonemal, heavy chain 17 5.0
ODAD2 outer dynein arm docking complex subunit 2 5.0
CFAP144 cilia and flagella associated protein 144 5.0
RPGRIP1L RPGRIP1-like 5.0
DYNLT4 dynein light chain Tctex-type 4 5.0
PACRG PARK2 co-regulated 5.0
DRC4 dynein regulatory complex subunit 4 5.0
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 4.0
RSPH14 radial spoke head 14 homolog (Chlamydomonas) 4.0
CFAP70 cilia and flagella associated protein 70 4.0
CFAP206 cilia and flagella associated protein 206 4.0
CFAP74 cilia and flagella associated protein 74 4.0
WDR35 WD repeat domain 35 4.0
IFT140 intraflagellar transport 140 4.0
CFAP91 cilia and flagella associated protein 91 4.0
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 4.0
CFAP73 cilia and flagella associated protein 73 4.0
CFAP46 cilia and flagella associated protein 46 4.0
CFAP45 cilia and flagella associated protein 45 4.0
DYNC2I2 dynein 2 intermediate chain 2 4.0
ODAD1 outer dynein arm docking complex subunit 1 4.0
SEPTIN2 septin 2 4.0
SEPTIN7 septin 7 4.0
SEPTIN9 septin 9 4.0
BBOF1 basal body orientation factor 1 4.0
DNAI4 dynein axonemal intermediate chain 4 4.0
ODAD4 outer dynein arm docking complex subunit 4 4.0
CFAP251 cilia and flagella associated protein 251 4.0
ODAD3 outer dynein arm docking complex subunit 3 4.0
CFAP43 cilia and flagella associated protein 43 4.0
DNAL1 dynein, axonemal, light chain 1 4.0
CCDC40 coiled-coil domain containing 40 4.0
ATG7 autophagy related 7 4.0
ATG5 autophagy related 5 4.0
RSPH4A radial spoke head 4 homolog A (Chlamydomonas) 4.0
IQUB IQ motif and ubiquitin domain containing 4.0
ROPN1L rhophilin associated tail protein 1-like 4.0
CFAP100 cilia and flagella associated protein 100 4.0
RP1L1 retinitis pigmentosa 1-like 1 4.0
RSPH9 radial spoke head 9 homolog (Chlamydomonas) 4.0
DNAH1 dynein, axonemal, heavy chain 1 4.0
CFAP221 cilia and flagella associated protein 221 4.0
DNAH2 dynein, axonemal, heavy chain 2 4.0
DNAH11 dynein, axonemal, heavy chain 11 4.0
SPAG6 sperm associated antigen 6 4.0
CFAP54 cilia and flagella associated 54 4.0
GABARAP GABA(A) receptor-associated protein 4.0
RSPH3 radial spoke 3 homolog (Chlamydomonas) 4.0
RSPH1 radial spoke head 1 homolog (Chlamydomonas) 4.0
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4 4.0
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) 4.0
EFHC1 EF-hand domain (C-terminal) containing 1 4.0
WDR11 WD repeat domain 11 4.0
ARL6 ADP-ribosylation factor-like 6 4.0
CFAP61 cilia and flagella associated protein 61 4.0
SPEF1 sperm flagellar 1 4.0
MAP4 microtubule-associated protein 4 4.0
BRWD1 bromodomain and WD repeat domain containing 1 4.0
DYDC1 DPY30 domain containing 1 4.0
DRC1 dynein regulatory complex subunit 1 4.0
DNAJB13 DnaJ (Hsp40) homolog, subfamily B, member 13 4.0
CAMSAP3 calmodulin regulated spectrin-associated protein family, member 3 4.0
NME5 NME/NM23 family member 5 4.0
ATG16L1 autophagy related 16-like 1 (S. cerevisiae) 4.0
TTLL8 tubulin tyrosine ligase-like family member 8 4.0
AMBRA1 autophagy/beclin-1 regulator 1 4.0
DNAH5 dynein, axonemal, heavy chain 5 4.0
ATG14 autophagy related 14 4.0
TTLL3 tubulin tyrosine ligase-like family member 3 4.0
DNAI1 dynein, axonemal, intermediate chain 1 3.0
DNAI2 dynein, axonemal, intermediate chain 2 3.0
DNAI3 dynein axonemal intermediate chain 3 3.0
CCDC63 coiled-coil domain containing 63 3.0
NME8 NME/NM23 family member 8 3.0
CFAP36 cilia and flagella associated protein 36 3.0
SPATA4 spermatogenesis associated 4 3.0
SPAG17 sperm associated antigen 17 3.0
SPAG16 sperm associated antigen 16 3.0
IFT70A intraflagellar transport 70A 3.0
IFT70B intraflagellar transport 70B 3.0
LINC02610 long intergenic non-protein coding RNA 2610 3.0
ADAMTSL4-AS2 ADAMTSL4 antisense RNA 2 3.0
DNAAF19 dynein axonemal assembly factor 19 3.0
RSPH6A radial spoke head 6 homolog A (Chlamydomonas) 3.0
DRC2 dynein regulatory complex subunit 2 3.0
DNAH12 dynein, axonemal, heavy chain 12 3.0
LRRC43 leucine rich repeat containing 43 3.0
WDR54 WD repeat domain 54 3.0
MAPRE2 microtubule-associated protein, RP/EB family, member 2 3.0
DNHD1 dynein heavy chain domain 1 3.0
CCDC39 coiled-coil domain containing 39 3.0
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1 3.0
HYDIN HYDIN, axonemal central pair apparatus protein 3.0
WDPCP WD repeat containing planar cell polarity effector 3.0
KIFAP3 kinesin-associated protein 3 3.0
BBS7 Bardet-Biedl syndrome 7 3.0
LCA5L Leber congenital amaurosis 5-like 3.0
DNAH8 dynein, axonemal, heavy chain 8 3.0
IFT172 intraflagellar transport 172 3.0
LCA5 Leber congenital amaurosis 5 3.0
SAXO2 stabilizer of axonemal microtubules 2 3.0
DNAI7 dynein axonemal intermediate chain 7 3.0
IFT54 intraflagellar transport 54 3.0
BBS1 Bardet-Biedl syndrome 1 3.0
DNAH7 dynein, axonemal, heavy chain 7 3.0
DYNC2LI1 dynein, cytoplasmic 2, light intermediate chain 1 3.0
CFAP52 cilia and flagella associated protein 52 3.0