| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Azithromycin (hydrate) perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Azithromycin (hydrate)_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.331099 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.147489 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.117281 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0933417 |
| PLAT | plasminogen activator, tissue | 0.083462 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0818285 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0788004 |
| MT2A | metallothionein 2A | 0.0736893 |
| MYADM | myeloid-associated differentiation marker | 0.0647581 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0647011 |
| CENPF | centromere protein F, 350/400kDa | 0.0620381 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0561634 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0547143 |
| HDAC9 | histone deacetylase 9 | 0.053569 |
| ASPH | aspartate beta-hydroxylase | 0.0528247 |
| CD44 | CD44 molecule (Indian blood group) | 0.0525735 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0503721 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0502932 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0495971 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0485922 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0484911 |
| MSN | moesin | 0.0472079 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0466657 |
| CSTB | cystatin B (stefin B) | 0.0462876 |
| SON | SON DNA binding protein | 0.0458712 |
| DST | dystonin | 0.0437791 |
| MKI67 | marker of proliferation Ki-67 | 0.043431 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0427885 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0420802 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0420245 |
| GOLGB1 | golgin B1 | 0.0419901 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0418756 |
| BPTF | bromodomain PHD finger transcription factor | 0.0409175 |
| LAMB1 | laminin, beta 1 | 0.0403832 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0394949 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0382687 |
| VMP1 | vacuole membrane protein 1 | 0.0382104 |
| TPR | translocated promoter region, nuclear basket protein | 0.0381738 |
| TPM3 | tropomyosin 3 | 0.0380408 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0374488 |
| RND3 | Rho family GTPase 3 | 0.0355738 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.035121 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0337682 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0333366 |
| RRBP1 | ribosome binding protein 1 | 0.0323168 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0321424 |
| SET | SET nuclear proto-oncogene | 0.0312411 |
| EFNA5 | ephrin-A5 | 0.0311147 |
| DEK | DEK proto-oncogene | 0.0309957 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0308975 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0306529 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0305519 |
| DSPP | dentin sialophosphoprotein | 0.030533 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0303261 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | 0.0292079 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0290283 |
| RPS2 | ribosomal protein S2 | 0.0289594 |
| MCL1 | myeloid cell leukemia 1 | 0.0286597 |
| SMAD3 | SMAD family member 3 | 0.0282993 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0281674 |
| RPS6 | ribosomal protein S6 | 0.0280851 |
| CDH13 | cadherin 13 | 0.0280251 |
| TMF1 | TATA element modulatory factor 1 | 0.0277787 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0276937 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.027688 |
| JMJD1C | jumonji domain containing 1C | 0.0276208 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0270187 |
| SEPTIN7 | septin 7 | 0.0269756 |
| CEP350 | centrosomal protein 350kDa | 0.0268647 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0268216 |
| VCL | vinculin | 0.0266802 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0265552 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0265451 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0265248 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0261242 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | 0.0255479 |
| SQSTM1 | sequestosome 1 | 0.0254723 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0253618 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0252307 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0250808 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0249243 |
| SPDL1 | spindle apparatus coiled-coil protein 1 | 0.0247295 |
| SP100 | SP100 nuclear antigen | 0.0243326 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0243047 |
| TUT7 | terminal uridylyl transferase 7 | 0.0243002 |
| GOLM2 | golgi membrane protein 2 | 0.0242991 |
| BCL2L1 | BCL2-like 1 | 0.0242125 |
| GLIS3 | GLIS family zinc finger 3 | 0.0241196 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.024059 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0240125 |
| RPS12 | ribosomal protein S12 | 0.0239424 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0238742 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0237784 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.023643 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0235618 |
| DNMBP | dynamin binding protein | 0.0234486 |
| RPLP2 | ribosomal protein, large, P2 | 0.0234297 |
| MB21D2 | Mab-21 domain containing 2 | 0.0234084 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0233707 |
| ERBIN | erbb2 interacting protein | 0.02336 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.197916 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.197508 |
| TMSB10 | thymosin beta 10 | -0.137941 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.127446 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.127151 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.125102 |
| FBN1 | fibrillin 1 | -0.108115 |
| COL5A1 | collagen, type V, alpha 1 | -0.105665 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0878474 |
| LOX | lysyl oxidase | -0.0863229 |
| THBS2 | thrombospondin 2 | -0.0823595 |
| LOXL2 | lysyl oxidase-like 2 | -0.0799612 |
| VIM | vimentin | -0.0791823 |
| FN1 | fibronectin 1 | -0.0787006 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0771381 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0678684 |
| COL1A2 | collagen, type I, alpha 2 | -0.0659585 |
| COL5A2 | collagen, type V, alpha 2 | -0.0629438 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0599667 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0581614 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0563608 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0558975 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0537374 |
| AUTS2 | autism susceptibility candidate 2 | -0.0531674 |
| MSI2 | musashi RNA-binding protein 2 | -0.0525908 |
| S100A6 | S100 calcium binding protein A6 | -0.0517896 |
| PKM | pyruvate kinase, muscle | -0.0517057 |
| PODXL | podocalyxin-like | -0.0509463 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0488673 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0487951 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0483905 |
| SUCNR1 | succinate receptor 1 | -0.0478814 |
| HLA-B | major histocompatibility complex, class I, B | -0.0467596 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0450563 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0440447 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0438689 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0438175 |
| UBC | ubiquitin C | -0.0418991 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0409884 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0408682 |
| NDRG1 | N-myc downstream regulated 1 | -0.0402783 |
| CD109 | CD109 molecule | -0.0394473 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0389742 |
| ANXA2 | annexin A2 | -0.0377659 |
| FSTL1 | follistatin-like 1 | -0.0371266 |
| TPM1 | tropomyosin 1 (alpha) | -0.0347174 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0344852 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0340926 |
| TNS3 | tensin 3 | -0.0340704 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.033654 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0335893 |
| AHNAK | AHNAK nucleoprotein | -0.03336 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0332945 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | -0.0330015 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0318702 |
| LOC112694756 | uncharaterized LOC112694756 | -0.030614 |
| TAGLN2 | transgelin 2 | -0.0304503 |
| FLNA | filamin A, alpha | -0.0291208 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0289039 |
| LMNA | lamin A/C | -0.0287608 |
| PGK1 | phosphoglycerate kinase 1 | -0.0287437 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0272688 |
| SAR1A | secretion associated, Ras related GTPase 1A | -0.0270572 |
| ADM | adrenomedullin | -0.0270142 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0268333 |
| COPA | coatomer protein complex, subunit alpha | -0.0268232 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0259683 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0259139 |
| S100A4 | S100 calcium binding protein A4 | -0.0257792 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0256606 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.025615 |
| INSIG1 | insulin induced gene 1 | -0.0252502 |
| JAZF1 | JAZF zinc finger 1 | -0.0250601 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0250358 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.024732 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0240275 |
| TMSB4X | thymosin beta 4, X-linked | -0.0237847 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.0233886 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0232401 |
| SBF2 | SET binding factor 2 | -0.023105 |
| COL3A1 | collagen, type III, alpha 1 | -0.0225628 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0225534 |
| HLA-E | major histocompatibility complex, class I, E | -0.02235 |
| WTAP | Wilms tumor 1 associated protein | -0.0223118 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0222597 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0219406 |
| RHOQ | ras homolog family member Q | -0.0218491 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0218032 |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) | -0.02167 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.0213022 |
| FLNB | filamin B, beta | -0.0210843 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0209577 |
| KRT81 | keratin 81, type II | -0.020625 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0205025 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0204498 |
| INSIG2 | insulin induced gene 2 | -0.020307 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0201444 |
| SCARB2 | scavenger receptor class B, member 2 | -0.020088 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0199997 |
| IL7R | interleukin 7 receptor | -0.0198073 |
