| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Azithromycin (hydrate) perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Azithromycin (hydrate)_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.190294 |
| VMP1 | vacuole membrane protein 1 | 0.177515 |
| TMEM41B | transmembrane protein 41B | 0.124192 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.114911 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.11084 |
| MMP12 | matrix metallopeptidase 12 | 0.104733 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0989326 |
| JMJD1C | jumonji domain containing 1C | 0.0922975 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0916216 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.09066 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0856225 |
| RPS12 | ribosomal protein S12 | 0.0847294 |
| MKI67 | marker of proliferation Ki-67 | 0.0790061 |
| HMGA2 | high mobility group AT-hook 2 | 0.078674 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0766306 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | 0.0754746 |
| YAP1 | Yes-associated protein 1 | 0.0689698 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0685772 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0621639 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0611721 |
| RTN4 | reticulon 4 | 0.0608145 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0606427 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0600871 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0598189 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0580529 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0572345 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0541991 |
| ZNF638 | zinc finger protein 638 | 0.0540162 |
| RPS2 | ribosomal protein S2 | 0.0516777 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0502241 |
| TPM3 | tropomyosin 3 | 0.0502033 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0486204 |
| FBXO11 | F-box protein 11 | 0.0485801 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0483597 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0475721 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | 0.0473051 |
| IPO7 | importin 7 | 0.0470963 |
| KIF5B | kinesin family member 5B | 0.0467394 |
| AREG | amphiregulin | 0.0460324 |
| TPR | translocated promoter region, nuclear basket protein | 0.043623 |
| BPTF | bromodomain PHD finger transcription factor | 0.0423666 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.041972 |
| RPS6 | ribosomal protein S6 | 0.0418688 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0415754 |
| CEP350 | centrosomal protein 350kDa | 0.0409712 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0408132 |
| YBX3 | Y box binding protein 3 | 0.0403225 |
| GOLGA4 | golgin A4 | 0.0398888 |
| DHX36 | DEAH (Asp-Glu-Ala-His) box polypeptide 36 | 0.0385384 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0382039 |
| WWOX | WW domain containing oxidoreductase | 0.037269 |
| PRKCI | protein kinase C, iota | 0.0372277 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.036843 |
| RPS7 | ribosomal protein S7 | 0.0367549 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.036617 |
| VIM | vimentin | 0.0364671 |
| TAOK1 | TAO kinase 1 | 0.036357 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0361736 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.034773 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0337855 |
| PDGFC | platelet derived growth factor C | 0.0329387 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0325912 |
| ENO1 | enolase 1, (alpha) | 0.0324978 |
| RCOR1 | REST corepressor 1 | 0.0318609 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0315561 |
| TMCC1 | transmembrane and coiled-coil domain family 1 | 0.0314505 |
| PCM1 | pericentriolar material 1 | 0.0313493 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0312324 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.030338 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0302049 |
| CCDC88A | coiled-coil domain containing 88A | 0.0300848 |
| SETD5 | SET domain containing 5 | 0.0299494 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0298078 |
| RRM2 | ribonucleotide reductase M2 | 0.0296384 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0291071 |
| ERBIN | erbb2 interacting protein | 0.0291012 |
| GOLGB1 | golgin B1 | 0.0290609 |
| PHACTR4 | phosphatase and actin regulator 4 | 0.0290404 |
| EDARADD | EDAR-associated death domain | 0.028571 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0281624 |
| USP34 | ubiquitin specific peptidase 34 | 0.0273354 |
| H1-2 | H1.2 linker histone, cluster member | 0.0272702 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0268879 |
| TLK1 | tousled-like kinase 1 | 0.0268816 |
| DSPP | dentin sialophosphoprotein | 0.0265749 |
| H1-4 | H1.4 linker histone, cluster member | 0.0265273 |
| BRD2 | bromodomain containing 2 | 0.0262978 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0262765 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0262155 |
| RPS8 | ribosomal protein S8 | 0.0261485 |
| ASPH | aspartate beta-hydroxylase | 0.0258775 |
| TPI1 | triosephosphate isomerase 1 | 0.0256636 |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 | 0.0254823 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0251969 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0251268 |
| ADIPOR2 | adiponectin receptor 2 | 0.0250922 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0248624 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0248142 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0248103 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.024788 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.161689 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0852127 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0819572 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0621319 |
| NLGN1 | neuroligin 1 | -0.0601287 |
| RPL35A | ribosomal protein L35a | -0.0559042 |
| HMGA1 | high mobility group AT-hook 1 | -0.0496815 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0485676 |
| PCDH7 | protocadherin 7 | -0.0481151 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.047219 |
| MYL12B | myosin, light chain 12B, regulatory | -0.046807 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0465931 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.0460173 |
| PFN1 | profilin 1 | -0.0433377 |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) | -0.0424986 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0410204 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0403573 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0391141 |
| PTMA | prothymosin, alpha | -0.0372074 |
| RPS24 | ribosomal protein S24 | -0.0367006 |
| CBX3 | chromobox homolog 3 | -0.036408 |
| CLDN1 | claudin 1 | -0.0356442 |
| PTMS | parathymosin | -0.034627 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0345004 |
| HLA-A | major histocompatibility complex, class I, A | -0.034222 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0339478 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0338684 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0323782 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0304657 |
| POTEF | POTE ankyrin domain family, member F | -0.0298053 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0294561 |
| CMIP | c-Maf inducing protein | -0.0289046 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0282637 |
| ACTG1 | actin gamma 1 | -0.0279942 |
| TMEM123 | transmembrane protein 123 | -0.0278098 |
| RPLP0 | ribosomal protein, large, P0 | -0.0259539 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0255914 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0232756 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0231045 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0222089 |
| TUBA1B | tubulin, alpha 1b | -0.0221164 |
| MTCL1 | microtubule crosslinking factor 1 | -0.022047 |
| FLNA | filamin A, alpha | -0.0218626 |
| S100A6 | S100 calcium binding protein A6 | -0.0217875 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0213208 |
| RASAL2 | RAS protein activator like 2 | -0.0211725 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0207262 |
| RPS19 | ribosomal protein S19 | -0.0205858 |
| KLHL24 | kelch-like family member 24 | -0.0204826 |
| TGM2 | transglutaminase 2 | -0.0204318 |
| SYT1 | synaptotagmin I | -0.0202578 |
| SDHA | succinate dehydrogenase complex, subunit A, flavoprotein (Fp) | -0.0200047 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.019901 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0199005 |
| FSTL5 | follistatin-like 5 | -0.0198989 |
| H1-0 | H1.0 linker histone | -0.0198105 |
| TENM3 | teneurin transmembrane protein 3 | -0.0191546 |
| LMO7 | LIM domain 7 | -0.0186232 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0183084 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0180918 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.0180469 |
| THSD7A | thrombospondin, type I, domain containing 7A | -0.0178738 |
| TENT4A | terminal nucleotidyltransferase 4A | -0.0178211 |
| RPS16 | ribosomal protein S16 | -0.0178006 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0176793 |
| RNF216 | ring finger protein 216 | -0.0173641 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0172274 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0172242 |
| RPS9 | ribosomal protein S9 | -0.0170042 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0169393 |
| RPS21 | ribosomal protein S21 | -0.0168612 |
| PKM | pyruvate kinase, muscle | -0.0168515 |
| ZNF207 | zinc finger protein 207 | -0.0168464 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | -0.0167573 |
| PCNP | PEST proteolytic signal containing nuclear protein | -0.0166346 |
| TIGAR | TP53 induced glycolysis regulatory phosphatase | -0.016552 |
| GART | phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase | -0.0165439 |
| KSR2 | kinase suppressor of ras 2 | -0.0163324 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.016264 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0162271 |
| RPL32 | ribosomal protein L32 | -0.0159206 |
| RPL19 | ribosomal protein L19 | -0.0158855 |
| SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 | -0.0158281 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0157109 |
| BSG | basigin (Ok blood group) | -0.0157103 |
| BCHE | butyrylcholinesterase | -0.0156914 |
| AHNAK | AHNAK nucleoprotein | -0.0154346 |
| HDLBP | high density lipoprotein binding protein | -0.0152594 |
| RHBDD1 | rhomboid domain containing 1 | -0.0152434 |
| SRSF1 | serine/arginine-rich splicing factor 1 | -0.0151352 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | -0.0150809 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0148744 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0148286 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | -0.0147745 |
| GASK1B | golgi associated kinase 1B | -0.0146589 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0145991 |
| ANKRD28 | ankyrin repeat domain 28 | -0.014551 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0144631 |
| TRIP13 | thyroid hormone receptor interactor 13 | -0.0144459 |
| NCAM2 | neural cell adhesion molecule 2 | -0.014428 |
