| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Azithromycin (hydrate) perturbation in A498 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Azithromycin (hydrate)_A498 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.205585 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.145046 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0989893 |
| B2M | beta-2-microglobulin | 0.0661458 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0624899 |
| MSN | moesin | 0.0562495 |
| IFI44L | interferon-induced protein 44-like | 0.0502898 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.048793 |
| TPM3 | tropomyosin 3 | 0.0481034 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0474509 |
| OPTN | optineurin | 0.0472311 |
| RPS2 | ribosomal protein S2 | 0.0420007 |
| MYADM | myeloid-associated differentiation marker | 0.0396812 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0385145 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0382627 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0379525 |
| CD44 | CD44 molecule (Indian blood group) | 0.0361271 |
| VIM | vimentin | 0.0358888 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.035887 |
| MX1 | MX dynamin-like GTPase 1 | 0.0330519 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0309189 |
| NAV2 | neuron navigator 2 | 0.0308407 |
| ANXA5 | annexin A5 | 0.0307068 |
| SET | SET nuclear proto-oncogene | 0.0305953 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0304569 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0291999 |
| RPS8 | ribosomal protein S8 | 0.0283297 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0275865 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0268041 |
| RPS27A | ribosomal protein S27a | 0.0266401 |
| CALR | calreticulin | 0.0265859 |
| VEGFA | vascular endothelial growth factor A | 0.0264744 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0261328 |
| PAX8 | paired box 8 | 0.0260716 |
| RPS12 | ribosomal protein S12 | 0.025825 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0253605 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0252926 |
| XPO1 | exportin 1 | 0.025032 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0249126 |
| CDCP1 | CUB domain containing protein 1 | 0.0247564 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.0246482 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0246054 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | 0.0245787 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0243956 |
| NRP2 | neuropilin 2 | 0.0242751 |
| TMF1 | TATA element modulatory factor 1 | 0.0242163 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0240792 |
| MKI67 | marker of proliferation Ki-67 | 0.0237322 |
| RND3 | Rho family GTPase 3 | 0.0236797 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0233557 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0231189 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0226663 |
| UBC | ubiquitin C | 0.0225587 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0215576 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0215481 |
| TPR | translocated promoter region, nuclear basket protein | 0.0215112 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | 0.0214107 |
| HDGF | hepatoma-derived growth factor | 0.0211231 |
| SQSTM1 | sequestosome 1 | 0.0205025 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.020419 |
| WWOX | WW domain containing oxidoreductase | 0.0204149 |
| LAMB1 | laminin, beta 1 | 0.0202702 |
| NIBAN1 | niban apoptosis regulator 1 | 0.020214 |
| ITM2B | integral membrane protein 2B | 0.0201604 |
| LYST | lysosomal trafficking regulator | 0.0201064 |
| CANX | calnexin | 0.020086 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0198929 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0198563 |
| CENPF | centromere protein F, 350/400kDa | 0.0197684 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0196956 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0195013 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0194415 |
| PCBP2 | poly(rC) binding protein 2 | 0.0193403 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0192852 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0189186 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.018725 |
| SEPTIN7 | septin 7 | 0.0186065 |
| XRN1 | 5'-3' exoribonuclease 1 | 0.0185004 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0182413 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.017929 |
| DSTN | destrin (actin depolymerizing factor) | 0.017708 |
| DEK | DEK proto-oncogene | 0.0174826 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | 0.0174144 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0173266 |
| DSPP | dentin sialophosphoprotein | 0.017307 |
| SEPTIN9 | septin 9 | 0.0172176 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0171067 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0170379 |
| BPTF | bromodomain PHD finger transcription factor | 0.0170095 |
| TUBA1B | tubulin, alpha 1b | 0.0170081 |
| ENO1 | enolase 1, (alpha) | 0.0169692 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0168277 |
| FTL | ferritin, light polypeptide | 0.0167099 |
| SP100 | SP100 nuclear antigen | 0.0166167 |
| MSH6 | mutS homolog 6 | 0.016579 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0163511 |
| PLIN2 | perilipin 2 | 0.0162766 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 | 0.0161102 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0160853 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0160841 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FRMD4A | FERM domain containing 4A | -0.20566 |
| GPC6 | glypican 6 | -0.195806 |
| GLIS3 | GLIS family zinc finger 3 | -0.105672 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0929991 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0925153 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0905359 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0887861 |
| FAT1 | FAT atypical cadherin 1 | -0.0638629 |
| VCL | vinculin | -0.0638107 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0622644 |
| TMSB10 | thymosin beta 10 | -0.060798 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0571139 |
| PALLD | palladin, cytoskeletal associated protein | -0.0557879 |
| CP | ceruloplasmin (ferroxidase) | -0.0555206 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0540844 |
| SCFD2 | sec1 family domain containing 2 | -0.0536984 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.053531 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0535155 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.0524435 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0518828 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0502791 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0501949 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0499551 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | -0.0486706 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0476626 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | -0.047114 |
| TNS3 | tensin 3 | -0.0463748 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0463461 |
| STK17A | serine/threonine kinase 17a | -0.0450993 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0427224 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0416992 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0414582 |
| MORF4L2 | mortality factor 4 like 2 | -0.0413227 |
| SBF2 | SET binding factor 2 | -0.0408614 |
| SPAG9 | sperm associated antigen 9 | -0.0400778 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0385779 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0384953 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0373398 |
| HPCAL1 | hippocalcin-like 1 | -0.0368772 |
| PTK2 | protein tyrosine kinase 2 | -0.0362254 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0359173 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0356601 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0353155 |
| CMIP | c-Maf inducing protein | -0.0351071 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0347604 |
| GDF15 | growth differentiation factor 15 | -0.0347485 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0347345 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0345949 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0342216 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0342168 |
| NF1 | neurofibromin 1 | -0.0337586 |
| RPS24 | ribosomal protein S24 | -0.0332509 |
| RBM39 | RNA binding motif protein 39 | -0.0332024 |
| RNF213 | ring finger protein 213 | -0.0329259 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0327889 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.032734 |
| CLINT1 | clathrin interactor 1 | -0.0327049 |
| TGFB2 | transforming growth factor, beta 2 | -0.032427 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0322653 |
| COG5 | component of oligomeric golgi complex 5 | -0.0322607 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0321781 |
| TGFA | transforming growth factor, alpha | -0.0317257 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | -0.0316874 |
| ETV6 | ets variant 6 | -0.0316525 |
| OSMR | oncostatin M receptor | -0.0316143 |
| CLTC | clathrin, heavy chain (Hc) | -0.031249 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0309844 |
| FLNA | filamin A, alpha | -0.0308352 |
| ATP13A3 | ATPase type 13A3 | -0.0306333 |
| POTEF | POTE ankyrin domain family, member F | -0.0303229 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0302924 |
| RIC1 | RAB6A GEF complex partner 1 | -0.0302348 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0301766 |
| DAPK1 | death-associated protein kinase 1 | -0.0301665 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0299966 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0296901 |
| PREX2 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 | -0.0295517 |
| ARF1 | ADP-ribosylation factor 1 | -0.0291955 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0289955 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0288461 |
| LTN1 | listerin E3 ubiquitin protein ligase 1 | -0.0288415 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0287977 |
| COPA | coatomer protein complex, subunit alpha | -0.0287162 |
| RPL35A | ribosomal protein L35a | -0.0286734 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0283935 |
| SORCS2 | sortilin-related VPS10 domain containing receptor 2 | -0.0283868 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0282729 |
| SDCBP | syndecan binding protein (syntenin) | -0.0281857 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | -0.0280052 |
| ZNF644 | zinc finger protein 644 | -0.0277387 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0274718 |
| HDLBP | high density lipoprotein binding protein | -0.0272784 |
| NUP214 | nucleoporin 214kDa | -0.0272328 |
| APOL2 | apolipoprotein L, 2 | -0.0270938 |
| OXR1 | oxidation resistance 1 | -0.0265082 |
| CADM1 | cell adhesion molecule 1 | -0.0264673 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0264156 |
| FUS | FUS RNA binding protein | -0.0264052 |
| SMAD3 | SMAD family member 3 | -0.026349 |
| ACTG1 | actin gamma 1 | -0.0262039 |
