| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Azithromycin (hydrate) perturbation in A549 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Azithromycin (hydrate)_A549 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.419503 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.11834 |
| STC1 | stanniocalcin 1 | 0.112576 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.100698 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.085694 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0854676 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0743999 |
| RPS6 | ribosomal protein S6 | 0.0712582 |
| VMP1 | vacuole membrane protein 1 | 0.0614609 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0607578 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.054637 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0543468 |
| RPS2 | ribosomal protein S2 | 0.0536664 |
| MT2A | metallothionein 2A | 0.0522164 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0519951 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0505469 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0488673 |
| MCL1 | myeloid cell leukemia 1 | 0.0469769 |
| MSN | moesin | 0.0461112 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0426045 |
| ZFP36 | ZFP36 ring finger protein | 0.0408338 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0401048 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.0396911 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0394432 |
| VIM | vimentin | 0.0386251 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0385566 |
| RPS12 | ribosomal protein S12 | 0.0374465 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0366985 |
| WWOX | WW domain containing oxidoreductase | 0.0363342 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0357253 |
| AXL | AXL receptor tyrosine kinase | 0.0340565 |
| RPS8 | ribosomal protein S8 | 0.0336764 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0306907 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0305462 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0298726 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0290333 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0285853 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0271529 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0266774 |
| GRAMD1B | GRAM domain containing 1B | 0.0266309 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0264341 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0263059 |
| DSPP | dentin sialophosphoprotein | 0.0262784 |
| WWC1 | WW and C2 domain containing 1 | 0.025958 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0251232 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0247805 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0247768 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0243835 |
| MYADM | myeloid-associated differentiation marker | 0.022471 |
| RNF145 | ring finger protein 145 | 0.0220071 |
| RPS7 | ribosomal protein S7 | 0.0219918 |
| LAMC2 | laminin, gamma 2 | 0.0219253 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0218884 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0218739 |
| SET | SET nuclear proto-oncogene | 0.0213825 |
| RPL37A | ribosomal protein L37a | 0.0213111 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0212956 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0211261 |
| RPLP2 | ribosomal protein, large, P2 | 0.0210271 |
| RPL23 | ribosomal protein L23 | 0.0209826 |
| ITGB5 | integrin, beta 5 | 0.0206734 |
| HMGA2 | high mobility group AT-hook 2 | 0.0206182 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0199549 |
| MYO10 | myosin X | 0.0198863 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0190634 |
| CLU | clusterin | 0.018877 |
| BMP6 | bone morphogenetic protein 6 | 0.0186069 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0184922 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0183574 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0183409 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0183057 |
| RPL21 | ribosomal protein L21 | 0.0181722 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0181315 |
| MAP7 | microtubule-associated protein 7 | 0.018102 |
| RND3 | Rho family GTPase 3 | 0.0180275 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0178481 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0177655 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0175623 |
| RPS17 | ribosomal protein S17 | 0.0175404 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0174857 |
| PDZD8 | PDZ domain containing 8 | 0.0174411 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0171797 |
| RPS3 | ribosomal protein S3 | 0.017057 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0169351 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0168647 |
| USP47 | ubiquitin specific peptidase 47 | 0.0166977 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0165067 |
| PCBP2 | poly(rC) binding protein 2 | 0.0164338 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0164272 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0164014 |
| PABPN1 | poly(A) binding protein, nuclear 1 | 0.0163579 |
| ZNF638 | zinc finger protein 638 | 0.0161809 |
| TOP1 | topoisomerase (DNA) I | 0.0161486 |
| BPTF | bromodomain PHD finger transcription factor | 0.0160489 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0159145 |
| ANXA5 | annexin A5 | 0.0157085 |
| MT1X | metallothionein 1X | 0.0154855 |
| CCDC88A | coiled-coil domain containing 88A | 0.015451 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0154237 |
| H1-2 | H1.2 linker histone, cluster member | 0.0153908 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.165321 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.131193 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.120813 |
| RNF213 | ring finger protein 213 | -0.104001 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.094196 |
| NDRG1 | N-myc downstream regulated 1 | -0.0919069 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0894286 |
| ANXA2 | annexin A2 | -0.0777736 |
| PARD3 | par-3 family cell polarity regulator | -0.0693474 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0691108 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.0674991 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0661297 |
| AHNAK | AHNAK nucleoprotein | -0.0599902 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0596345 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0590193 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0581764 |
| CA12 | carbonic anhydrase XII | -0.0538987 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0534908 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0533783 |
| TXNRD1 | thioredoxin reductase 1 | -0.0532495 |
| TNS3 | tensin 3 | -0.0531999 |
| AUTS2 | autism susceptibility candidate 2 | -0.0531429 |
| PGK1 | phosphoglycerate kinase 1 | -0.0527358 |
| HDLBP | high density lipoprotein binding protein | -0.0519319 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0494624 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0489496 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0485466 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0485257 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0483729 |
| SBF2 | SET binding factor 2 | -0.0461572 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0459467 |
| ACTN4 | actinin, alpha 4 | -0.0450233 |
| PKM | pyruvate kinase, muscle | -0.0449354 |
| DAPK1 | death-associated protein kinase 1 | -0.0448411 |
| USP3 | ubiquitin specific peptidase 3 | -0.0440598 |
| ATG7 | autophagy related 7 | -0.0440376 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0426952 |
| FTL | ferritin, light polypeptide | -0.042649 |
| CLINT1 | clathrin interactor 1 | -0.0425767 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0425508 |
| MORF4L2 | mortality factor 4 like 2 | -0.0425503 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0416178 |
| LDHA | lactate dehydrogenase A | -0.0413481 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0405533 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0401456 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0391641 |
| CLTC | clathrin, heavy chain (Hc) | -0.0384473 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0379579 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0377911 |
| COPA | coatomer protein complex, subunit alpha | -0.0375854 |
| KIRREL3 | kin of IRRE like 3 (Drosophila) | -0.0375313 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0373133 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0372624 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.03693 |
| CANX | calnexin | -0.036772 |
| SPAG9 | sperm associated antigen 9 | -0.0365818 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | -0.0364296 |
| RPL4 | ribosomal protein L4 | -0.0361866 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.036141 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0359406 |
| MAP1B | microtubule-associated protein 1B | -0.0356729 |
| PTK2 | protein tyrosine kinase 2 | -0.0355663 |
| FLNA | filamin A, alpha | -0.0354151 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0352011 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | -0.0347104 |
| FNIP1 | folliculin interacting protein 1 | -0.034301 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0342282 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0341686 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0341273 |
| USP34 | ubiquitin specific peptidase 34 | -0.0336332 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0335652 |
| HELZ | helicase with zinc finger | -0.0334668 |
| TMSB4X | thymosin beta 4, X-linked | -0.0334371 |
| GOLGA4 | golgin A4 | -0.0331834 |
| UBC | ubiquitin C | -0.0330998 |
| PTMA | prothymosin, alpha | -0.0325359 |
| NAV2 | neuron navigator 2 | -0.0324071 |
| TKT | transketolase | -0.0323388 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0322815 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.032199 |
| KCTD9 | potassium channel tetramerization domain containing 9 | -0.0321902 |
| SRP54 | signal recognition particle 54kDa | -0.0315481 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0314587 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0313532 |
| ANXA4 | annexin A4 | -0.0313274 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0312959 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0312564 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0310756 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0309395 |
| SP100 | SP100 nuclear antigen | -0.0309392 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0307686 |
| COG5 | component of oligomeric golgi complex 5 | -0.0304147 |
| RPS24 | ribosomal protein S24 | -0.0300853 |
| WDR45B | WD repeat domain 45B | -0.0300086 |
| CMIP | c-Maf inducing protein | -0.029817 |
| PLEC | plectin | -0.0297469 |
| PMM2 | phosphomannomutase 2 | -0.0296949 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | -0.0292739 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0289529 |
| PLCB4 | phospholipase C, beta 4 | -0.0288179 |
