| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Azithromycin (hydrate) perturbation in AN3 CA cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Azithromycin (hydrate)_AN3 CA drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.126845 |
| RPS12 | ribosomal protein S12 | 0.0656362 |
| MYOF | myoferlin | 0.0608484 |
| FNIP1 | folliculin interacting protein 1 | 0.0586023 |
| RPS2 | ribosomal protein S2 | 0.0557003 |
| VEGFA | vascular endothelial growth factor A | 0.0548718 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0517492 |
| FRMD6 | FERM domain containing 6 | 0.0503649 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0476057 |
| ACTG1 | actin gamma 1 | 0.0425868 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0418302 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0414554 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | 0.0374032 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0345036 |
| TSC22D1 | TSC22 domain family, member 1 | 0.033438 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | 0.0325464 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0319774 |
| HMGA1 | high mobility group AT-hook 1 | 0.0287296 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0283429 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0271412 |
| TMEM41B | transmembrane protein 41B | 0.0269723 |
| ADIPOR2 | adiponectin receptor 2 | 0.025356 |
| SON | SON DNA binding protein | 0.0253275 |
| RPS8 | ribosomal protein S8 | 0.0247619 |
| KAT6B | K(lysine) acetyltransferase 6B | 0.0245997 |
| ANO6 | anoctamin 6 | 0.0245657 |
| ANK2 | ankyrin 2, neuronal | 0.0245268 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0241436 |
| WDR26 | WD repeat domain 26 | 0.0232318 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0227506 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.022515 |
| CREM | cAMP responsive element modulator | 0.0224631 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0221442 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 0.0219265 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0217805 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0216695 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0207529 |
| EPC2 | enhancer of polycomb homolog 2 (Drosophila) | 0.0207515 |
| EFNA5 | ephrin-A5 | 0.0207391 |
| RPL37A | ribosomal protein L37a | 0.0204946 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0203932 |
| PPIL4 | peptidylprolyl isomerase (cyclophilin)-like 4 | 0.0203883 |
| NBEA | neurobeachin | 0.0202921 |
| RABEP1 | rabaptin, RAB GTPase binding effector protein 1 | 0.0201845 |
| XPO1 | exportin 1 | 0.0194828 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0193516 |
| IPO7 | importin 7 | 0.0192367 |
| NCOA6 | nuclear receptor coactivator 6 | 0.019092 |
| RPS23 | ribosomal protein S23 | 0.0190717 |
| FMNL2 | formin-like 2 | 0.0190011 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0189373 |
| SH3PXD2A | SH3 and PX domains 2A | 0.0183424 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0183395 |
| CABIN1 | calcineurin binding protein 1 | 0.0182077 |
| GTF2IRD1 | GTF2I repeat domain containing 1 | 0.0179205 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0178854 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0178354 |
| YLPM1 | YLP motif containing 1 | 0.0178255 |
| DOCK11 | dedicator of cytokinesis 11 | 0.0177463 |
| TMF1 | TATA element modulatory factor 1 | 0.0176795 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | 0.0174805 |
| CADM2 | cell adhesion molecule 2 | 0.0174443 |
| MAPT | microtubule-associated protein tau | 0.0169209 |
| RTF1 | Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) | 0.0168687 |
| MMADHC | methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria | 0.016843 |
| ARRDC3 | arrestin domain containing 3 | 0.0168416 |
| EZR | ezrin | 0.0166492 |
| KIDINS220 | kinase D-interacting substrate, 220kDa | 0.0162243 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0162067 |
| OFD1 | oral-facial-digital syndrome 1 | 0.0161234 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0160786 |
| VMP1 | vacuole membrane protein 1 | 0.0160736 |
| CUX1 | cut-like homeobox 1 | 0.0159571 |
| COL5A2 | collagen, type V, alpha 2 | 0.015954 |
| DMXL1 | Dmx-like 1 | 0.0158462 |
| MRPS31 | mitochondrial ribosomal protein S31 | 0.0157921 |
| H1-2 | H1.2 linker histone, cluster member | 0.0157322 |
| MICU1 | mitochondrial calcium uptake 1 | 0.0156682 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0156501 |
| SFSWAP | splicing factor, suppressor of white-apricot family | 0.0156104 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0155187 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0154372 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0153628 |
| LOXL2 | lysyl oxidase-like 2 | 0.0153581 |
| NDUFA4L2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 | 0.0152398 |
| EGFR | epidermal growth factor receptor | 0.0152317 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0152208 |
| VIM | vimentin | 0.0151799 |
| RAB11FIP3 | RAB11 family interacting protein 3 (class II) | 0.0149066 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0148868 |
| MCU | mitochondrial calcium uniporter | 0.0148106 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0147944 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0147815 |
| MYO9A | myosin IXA | 0.0147774 |
| GTF2H1 | general transcription factor IIH, polypeptide 1, 62kDa | 0.0146405 |
| SNX30 | sorting nexin family member 30 | 0.0145685 |
| DENND4C | DENN/MADD domain containing 4C | 0.0145665 |
| EIF3J | eukaryotic translation initiation factor 3, subunit J | 0.0145584 |
| TAC4 | tachykinin 4 (hemokinin) | 0.0145441 |
| ZBTB40 | zinc finger and BTB domain containing 40 | 0.0145313 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MEST | mesoderm specific transcript | -0.240283 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.127039 |
| PEG10 | paternally expressed 10 | -0.126663 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.102781 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0998936 |
| CENPF | centromere protein F, 350/400kDa | -0.0897098 |
| PTMA | prothymosin, alpha | -0.087285 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0804384 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0800544 |
| TMSB4X | thymosin beta 4, X-linked | -0.0791945 |
| MEOX2 | mesenchyme homeobox 2 | -0.0762784 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0681842 |
| CANX | calnexin | -0.0673181 |
| NFIB | nuclear factor I/B | -0.0666853 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0615394 |
| TUBB | tubulin, beta class I | -0.0562408 |
| MKI67 | marker of proliferation Ki-67 | -0.0557038 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0554397 |
| MGP | matrix Gla protein | -0.0539722 |
| CALR | calreticulin | -0.0533425 |
| COL1A2 | collagen, type I, alpha 2 | -0.0532146 |
| NFIA | nuclear factor I/A | -0.0518015 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0492767 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0480191 |
| DIAPH3 | diaphanous-related formin 3 | -0.0479841 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0467608 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0454094 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | -0.0452593 |
| ZNF292 | zinc finger protein 292 | -0.0452102 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.045003 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.044143 |
| FTL | ferritin, light polypeptide | -0.043824 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0429868 |
| RPLP1 | ribosomal protein, large, P1 | -0.0429139 |
| PDGFC | platelet derived growth factor C | -0.0428401 |
| MATR3 | matrin 3 | -0.0426904 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0421621 |
| YBX1 | Y box binding protein 1 | -0.0416447 |
| ELOVL5 | ELOVL fatty acid elongase 5 | -0.0414361 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0406372 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0405743 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0403292 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0401014 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | -0.0394132 |
| TPK1 | thiamin pyrophosphokinase 1 | -0.0391462 |
| KNL1 | kinetochore scaffold 1 | -0.0390391 |
| QKI | QKI, KH domain containing, RNA binding | -0.038865 |
| TXNRD1 | thioredoxin reductase 1 | -0.0385391 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0381081 |
| KIF11 | kinesin family member 11 | -0.0380898 |
| TMSB10 | thymosin beta 10 | -0.0380465 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0376711 |
| HMGB2 | high mobility group box 2 | -0.0376265 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0369824 |
| HDLBP | high density lipoprotein binding protein | -0.0368046 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0365134 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0363404 |
| MT2A | metallothionein 2A | -0.0363082 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0362168 |
| FCHSD2 | FCH and double SH3 domains 2 | -0.0357675 |
| OLA1 | Obg-like ATPase 1 | -0.0356747 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0356279 |
| ITGAV | integrin, alpha V | -0.0354553 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0352283 |
| RPS19 | ribosomal protein S19 | -0.0351034 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.0346478 |
| RPL35A | ribosomal protein L35a | -0.0342848 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.033616 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | -0.0331262 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | -0.0327479 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0326927 |
| TTK | TTK protein kinase | -0.0325975 |
| ENAH | enabled homolog (Drosophila) | -0.0323527 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0321842 |
| RANBP17 | RAN binding protein 17 | -0.0319701 |
| FGFR2 | fibroblast growth factor receptor 2 | -0.0318383 |
| NDRG1 | N-myc downstream regulated 1 | -0.0318087 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.031679 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0316494 |
| BCOR | BCL6 corepressor | -0.0314449 |
| HMGB1 | high mobility group box 1 | -0.0312288 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0309148 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0307941 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0306666 |
| OGA | O-GlcNAcase | -0.0305439 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0305321 |
| WBP11 | WW domain binding protein 11 | -0.0304342 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0303829 |
| COTL1 | coactosin-like F-actin binding protein 1 | -0.0300974 |
| CCNI | cyclin I | -0.030041 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0299134 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0298941 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0296803 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0295646 |
| TPX2 | TPX2, microtubule-associated | -0.0294838 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0294167 |
| GPC6 | glypican 6 | -0.0293652 |
| NPR2 | natriuretic peptide receptor 2 | -0.0291432 |
| SMC3 | structural maintenance of chromosomes 3 | -0.0290499 |
| TBL1X | transducin (beta)-like 1X-linked | -0.0289306 |
