| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Azithromycin (hydrate) perturbation in AsPC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Azithromycin (hydrate)_AsPC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.191413 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | 0.153274 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0676046 |
| NDRG1 | N-myc downstream regulated 1 | 0.0655314 |
| EFNA5 | ephrin-A5 | 0.0630808 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0607984 |
| SACK1A | scaffolding CK1 anchoring protein A | 0.047266 |
| TXNIP | thioredoxin interacting protein | 0.0456448 |
| KLF6 | Kruppel-like factor 6 | 0.0449471 |
| CAB39 | calcium binding protein 39 | 0.0423084 |
| MT2A | metallothionein 2A | 0.0403188 |
| CD44 | CD44 molecule (Indian blood group) | 0.0373271 |
| RPS2 | ribosomal protein S2 | 0.0371771 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0325304 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0301321 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0283944 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0282735 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0277615 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | 0.02762 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0276045 |
| RPL21 | ribosomal protein L21 | 0.0265178 |
| BCL2L1 | BCL2-like 1 | 0.0264771 |
| WWC1 | WW and C2 domain containing 1 | 0.0256761 |
| CDCP1 | CUB domain containing protein 1 | 0.0253788 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0247836 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0242594 |
| VMP1 | vacuole membrane protein 1 | 0.0240224 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0235156 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0235026 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 | 0.0230461 |
| RPS7 | ribosomal protein S7 | 0.0224815 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0222331 |
| SET | SET nuclear proto-oncogene | 0.021781 |
| ATP13A3 | ATPase type 13A3 | 0.021514 |
| MYL12B | myosin, light chain 12B, regulatory | 0.0212353 |
| MT1X | metallothionein 1X | 0.0210715 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0209996 |
| SGMS2 | sphingomyelin synthase 2 | 0.0208891 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0206301 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0204659 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0203205 |
| TGM2 | transglutaminase 2 | 0.0200879 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0200224 |
| RPS12 | ribosomal protein S12 | 0.0199743 |
| LAMA4 | laminin, alpha 4 | 0.0187886 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0183847 |
| SREK1IP1 | SREK1-interacting protein 1 | 0.0180456 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0178001 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.017755 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0177167 |
| STC1 | stanniocalcin 1 | 0.0176616 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.017617 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0175968 |
| MYADM | myeloid-associated differentiation marker | 0.0172059 |
| DOCK5 | dedicator of cytokinesis 5 | 0.017194 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0171732 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0171388 |
| DSPP | dentin sialophosphoprotein | 0.0165092 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0164604 |
| MSN | moesin | 0.0164403 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0164313 |
| EFNB2 | ephrin-B2 | 0.0163613 |
| DUSP6 | dual specificity phosphatase 6 | 0.0162375 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0158836 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0158201 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0156711 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0154756 |
| S100A11 | S100 calcium binding protein A11 | 0.0152482 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0148015 |
| EXOC6B | exocyst complex component 6B | 0.0146232 |
| TMF1 | TATA element modulatory factor 1 | 0.0145708 |
| IRS2 | insulin receptor substrate 2 | 0.0144782 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.01432 |
| BPTF | bromodomain PHD finger transcription factor | 0.0141782 |
| ITGA6 | integrin, alpha 6 | 0.0139955 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0138666 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0136565 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0133828 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0131833 |
| SEPTIN9 | septin 9 | 0.0131463 |
| HIPK3 | homeodomain interacting protein kinase 3 | 0.0130126 |
| RPS3 | ribosomal protein S3 | 0.0129276 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.01269 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0126545 |
| PIP4K2A | phosphatidylinositol-5-phosphate 4-kinase, type II, alpha | 0.0125788 |
| SON | SON DNA binding protein | 0.0124623 |
| PNN | pinin, desmosome associated protein | 0.0124231 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | 0.0123527 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | 0.0123264 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0123035 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 | 0.0121985 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0121235 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.012008 |
| PTK2B | protein tyrosine kinase 2 beta | 0.0119569 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0118454 |
| RPS21 | ribosomal protein S21 | 0.0117951 |
| GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 | 0.0116776 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0116092 |
| PABPN1 | poly(A) binding protein, nuclear 1 | 0.0115757 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0114548 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.188955 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.177621 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.166239 |
| LMO7 | LIM domain 7 | -0.163249 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | -0.14873 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.147585 |
| TXNRD1 | thioredoxin reductase 1 | -0.127448 |
| TMSB10 | thymosin beta 10 | -0.1209 |
| PTMA | prothymosin, alpha | -0.109068 |
| MUC17 | mucin 17, cell surface associated | -0.102404 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.101656 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0941269 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0936238 |
| ARPC1A | actin related protein 2/3 complex, subunit 1A, 41kDa | -0.0894097 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0784509 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.0780532 |
| LMTK2 | lemur tyrosine kinase 2 | -0.07685 |
| HMGA1 | high mobility group AT-hook 1 | -0.0744185 |
| RPL35A | ribosomal protein L35a | -0.0700499 |
| EGR1 | early growth response 1 | -0.0695962 |
| TPM4 | tropomyosin 4 | -0.0694654 |
| TRRAP | transformation/transcription domain-associated protein | -0.0680724 |
| POTEF | POTE ankyrin domain family, member F | -0.0680448 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | -0.0664027 |
| AHNAK | AHNAK nucleoprotein | -0.0650842 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0616599 |
| PGK1 | phosphoglycerate kinase 1 | -0.061177 |
| EGFR | epidermal growth factor receptor | -0.0609555 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0608217 |
| FTL | ferritin, light polypeptide | -0.0608096 |
| KLK10 | kallikrein-related peptidase 10 | -0.0594938 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0584285 |
| UPP1 | uridine phosphorylase 1 | -0.0555745 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0545312 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0541183 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0538931 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0519636 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0517715 |
| COPA | coatomer protein complex, subunit alpha | -0.0514833 |
| NPSR1 | neuropeptide S receptor 1 | -0.0509907 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0503708 |
| VIM | vimentin | -0.0499814 |
| RIOK3 | RIO kinase 3 | -0.048958 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0476165 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0475815 |
| SPAG9 | sperm associated antigen 9 | -0.0470818 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0466328 |
| PRSS3 | protease, serine, 3 | -0.0462316 |
| VCAN | versican | -0.045654 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0454668 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0452771 |
| GNAS | GNAS complex locus | -0.045247 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0451307 |
| PLEC | plectin | -0.0439746 |
| SMC3 | structural maintenance of chromosomes 3 | -0.0436469 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0435272 |
| MORF4L2 | mortality factor 4 like 2 | -0.0432501 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0412957 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.040575 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.039569 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0392955 |
| HDLBP | high density lipoprotein binding protein | -0.0390816 |
| PMM2 | phosphomannomutase 2 | -0.0389507 |
| AK1 | adenylate kinase 1 | -0.0381603 |
| LDHA | lactate dehydrogenase A | -0.0379509 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0377668 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0377233 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0372445 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0371191 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0370145 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0369107 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0362851 |
| SP100 | SP100 nuclear antigen | -0.0362847 |
| COL17A1 | collagen, type XVII, alpha 1 | -0.0362411 |
| PTK2 | protein tyrosine kinase 2 | -0.0359563 |
| SVIL | supervillin | -0.0356763 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0355472 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | -0.03552 |
| RPL31 | ribosomal protein L31 | -0.0354829 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0354189 |
| USP34 | ubiquitin specific peptidase 34 | -0.0353532 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0352359 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0352142 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | -0.034896 |
| EZR | ezrin | -0.0346919 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0342203 |
| ATG16L1 | autophagy related 16-like 1 (S. cerevisiae) | -0.0341803 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0341214 |
| RBM39 | RNA binding motif protein 39 | -0.0339242 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0337913 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0335365 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | -0.0333309 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0332804 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0331251 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0329411 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0329285 |
| INPP5D | inositol polyphosphate-5-phosphatase, 145kDa | -0.0326081 |
| DIAPH2 | diaphanous-related formin 2 | -0.0325314 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0324755 |
| PKM | pyruvate kinase, muscle | -0.032098 |
