| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Azithromycin (hydrate) perturbation in C-33 A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Azithromycin (hydrate)_C-33 A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL5A2 | collagen, type V, alpha 2 | 0.132228 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.118403 |
| ZNF608 | zinc finger protein 608 | 0.10561 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | 0.0969305 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0902551 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0882025 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0681195 |
| JMJD1C | jumonji domain containing 1C | 0.0673269 |
| RPS2 | ribosomal protein S2 | 0.066794 |
| VMP1 | vacuole membrane protein 1 | 0.0653287 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.06053 |
| CCDC88A | coiled-coil domain containing 88A | 0.0586164 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0582496 |
| RPS12 | ribosomal protein S12 | 0.0577142 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0541664 |
| VCL | vinculin | 0.0539819 |
| SRSF4 | serine/arginine-rich splicing factor 4 | 0.0534283 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0532647 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0529002 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0518985 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0491254 |
| RPS6 | ribosomal protein S6 | 0.0476539 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0471135 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0463532 |
| NFIA | nuclear factor I/A | 0.0449913 |
| SMYD3 | SET and MYND domain containing 3 | 0.0448248 |
| ATG10 | autophagy related 10 | 0.0443482 |
| PHF21A | PHD finger protein 21A | 0.043328 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0432574 |
| NGLY1 | N-glycanase 1 | 0.0430554 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0427715 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0425035 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0422268 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.0421076 |
| PHACTR4 | phosphatase and actin regulator 4 | 0.0419696 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0419614 |
| BPTF | bromodomain PHD finger transcription factor | 0.0418664 |
| SET | SET nuclear proto-oncogene | 0.0415126 |
| TPR | translocated promoter region, nuclear basket protein | 0.0414627 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0402907 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0402267 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.0401878 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0390493 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0384015 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0382238 |
| ENO1 | enolase 1, (alpha) | 0.0379124 |
| CEP112 | centrosomal protein 112kDa | 0.037741 |
| PCM1 | pericentriolar material 1 | 0.0374672 |
| CENPF | centromere protein F, 350/400kDa | 0.0370811 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0370398 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0364471 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0362547 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0361592 |
| SETD5 | SET domain containing 5 | 0.0354341 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0352059 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0350083 |
| RBBP6 | retinoblastoma binding protein 6 | 0.0349253 |
| MKI67 | marker of proliferation Ki-67 | 0.0347273 |
| PRKCI | protein kinase C, iota | 0.033443 |
| H1-4 | H1.4 linker histone, cluster member | 0.0330342 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.032846 |
| ZNF644 | zinc finger protein 644 | 0.0325049 |
| OGA | O-GlcNAcase | 0.0321972 |
| WLS | wntless Wnt ligand secretion mediator | 0.0321346 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | 0.0316244 |
| ZC3H12B | zinc finger CCCH-type containing 12B | 0.03106 |
| ZSWIM5 | zinc finger, SWIM-type containing 5 | 0.0308945 |
| DENR | density-regulated protein | 0.0303713 |
| CDH18 | cadherin 18, type 2 | 0.0297585 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | 0.0296945 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0293758 |
| GPATCH8 | G patch domain containing 8 | 0.029265 |
| PABPN1 | poly(A) binding protein, nuclear 1 | 0.0292135 |
| HECTD1 | HECT domain containing E3 ubiquitin protein ligase 1 | 0.0291725 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0290318 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0289838 |
| MED13 | mediator complex subunit 13 | 0.0289253 |
| ZNF638 | zinc finger protein 638 | 0.0289043 |
| TOX | thymocyte selection-associated high mobility group box | 0.0288429 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0286628 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0286487 |
| ARFGEF3 | ARFGEF family member 3 | 0.0284825 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0284323 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0284088 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0283828 |
| H1-2 | H1.2 linker histone, cluster member | 0.0280954 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0280833 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0279806 |
| GOLM2 | golgi membrane protein 2 | 0.0277565 |
| ERBIN | erbb2 interacting protein | 0.0277507 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0274532 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0273819 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.0268574 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0265158 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0263656 |
| KMT2A | lysine (K)-specific methyltransferase 2A | 0.0261396 |
| PAXBP1 | PAX3 and PAX7 binding protein 1 | 0.0260676 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | 0.0259593 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | 0.0259191 |
| USP8 | ubiquitin specific peptidase 8 | 0.0257791 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.171023 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0968968 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0935493 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0924416 |
| NPAS3 | neuronal PAS domain protein 3 | -0.0860456 |
| RAD51B | RAD51 paralog B | -0.0854966 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0835133 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0796963 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.074307 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0685519 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0589442 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.058656 |
| TMSB10 | thymosin beta 10 | -0.0563301 |
| PTMA | prothymosin, alpha | -0.0528669 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0509719 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | -0.0499462 |
| TENM3 | teneurin transmembrane protein 3 | -0.0471521 |
| GAB2 | GRB2-associated binding protein 2 | -0.0459412 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0451066 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0436727 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.043048 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0424249 |
| HMGA1 | high mobility group AT-hook 1 | -0.0399258 |
| EFNA5 | ephrin-A5 | -0.0399243 |
| SLF1 | SMC5-SMC6 complex localization factor 1 | -0.0393629 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0393327 |
| FMNL2 | formin-like 2 | -0.0373034 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0368455 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0358041 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0351795 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0345961 |
| APP | amyloid beta (A4) precursor protein | -0.0344263 |
| PTK2 | protein tyrosine kinase 2 | -0.0342971 |
| RPL4 | ribosomal protein L4 | -0.0340836 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0333538 |
| RPS24 | ribosomal protein S24 | -0.0324955 |
| FAT1 | FAT atypical cadherin 1 | -0.0322749 |
| EMP1 | epithelial membrane protein 1 | -0.0322019 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.032146 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0317845 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0317023 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0309343 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0307523 |
| WDR45B | WD repeat domain 45B | -0.0306492 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.030646 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0304467 |
| FASN | fatty acid synthase | -0.0304414 |
| OLA1 | Obg-like ATPase 1 | -0.0303401 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0300855 |
| TMEM123 | transmembrane protein 123 | -0.0299388 |
| PARD3 | par-3 family cell polarity regulator | -0.0299137 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0298764 |
| ATP9A | ATPase, class II, type 9A | -0.0297233 |
| ATP5F1A | ATP synthase F1 subunit alpha | -0.0295887 |
| SALL4 | spalt-like transcription factor 4 | -0.0294318 |
| NPR2 | natriuretic peptide receptor 2 | -0.0292384 |
| TPD52 | tumor protein D52 | -0.0292119 |
| NAA15 | N(alpha)-acetyltransferase 15, NatA auxiliary subunit | -0.0291622 |
| RPL27A | ribosomal protein L27a | -0.0284783 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0284383 |
| ACTG1 | actin gamma 1 | -0.0284381 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0284175 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | -0.0280582 |
| MDN1 | MDN1, midasin homolog (yeast) | -0.0278374 |
| NUP58 | nucleoporin 58 | -0.027579 |
| RPS5 | ribosomal protein S5 | -0.0274585 |
| IGF2 | insulin-like growth factor 2 | -0.0273932 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0271975 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0269951 |
| FLNA | filamin A, alpha | -0.0269667 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0269058 |
| RPL35A | ribosomal protein L35a | -0.0268081 |
| ZNF217 | zinc finger protein 217 | -0.0267584 |
| PFN1 | profilin 1 | -0.026432 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0263694 |
| CBX3 | chromobox homolog 3 | -0.0263398 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0259938 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.025951 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0258341 |
| ZNF544 | zinc finger protein 544 | -0.0257898 |
| SRPK2 | SRSF protein kinase 2 | -0.025752 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0256998 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0254529 |
| PRPF8 | pre-mRNA processing factor 8 | -0.0254031 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0253432 |
| YBX1 | Y box binding protein 1 | -0.0252941 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0249174 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.0248162 |
| COG5 | component of oligomeric golgi complex 5 | -0.0246148 |
| EGR1 | early growth response 1 | -0.0245462 |
| GART | phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase | -0.0245457 |
| NBAS | neuroblastoma amplified sequence | -0.0245193 |
| SRSF1 | serine/arginine-rich splicing factor 1 | -0.024509 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0242809 |
| TENT4A | terminal nucleotidyltransferase 4A | -0.0241907 |
| RPS21 | ribosomal protein S21 | -0.0240522 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0240248 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | -0.0239234 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | -0.0232397 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0230455 |
