| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Azithromycin (hydrate) perturbation in C32 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Azithromycin (hydrate)_C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.185971 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.17624 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.143573 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.133498 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.122833 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.106179 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0986771 |
| MT2A | metallothionein 2A | 0.0972656 |
| ASPH | aspartate beta-hydroxylase | 0.0904902 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0745061 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0715147 |
| GPC6 | glypican 6 | 0.0704634 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0672779 |
| TPR | translocated promoter region, nuclear basket protein | 0.0563219 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0544476 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0526081 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0521321 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0498067 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0479861 |
| RPS12 | ribosomal protein S12 | 0.0461932 |
| VMP1 | vacuole membrane protein 1 | 0.0446067 |
| SMYD3 | SET and MYND domain containing 3 | 0.0438643 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0432343 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0431554 |
| RRBP1 | ribosome binding protein 1 | 0.0428702 |
| PCDH7 | protocadherin 7 | 0.042761 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.042475 |
| GOLGA4 | golgin A4 | 0.0409211 |
| LEF1 | lymphoid enhancer-binding factor 1 | 0.0407761 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0407236 |
| PRELID2 | PRELI domain containing 2 | 0.0392179 |
| GOLGB1 | golgin B1 | 0.0379837 |
| RPS2 | ribosomal protein S2 | 0.0379135 |
| MSN | moesin | 0.0379088 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0376728 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0371232 |
| ATXN1 | ataxin 1 | 0.037031 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0368606 |
| TMF1 | TATA element modulatory factor 1 | 0.0345144 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | 0.0335699 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0331574 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.032225 |
| TXNIP | thioredoxin interacting protein | 0.0320291 |
| RPS8 | ribosomal protein S8 | 0.0313094 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0312275 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0311447 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0295486 |
| VEGFA | vascular endothelial growth factor A | 0.0291546 |
| ZFYVE28 | zinc finger, FYVE domain containing 28 | 0.0289352 |
| PHF21A | PHD finger protein 21A | 0.0287977 |
| DST | dystonin | 0.0286294 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0285561 |
| RO60 | Ro60, Y RNA binding protein | 0.0281872 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0278561 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.027665 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.027378 |
| CANX | calnexin | 0.0270736 |
| RPS6 | ribosomal protein S6 | 0.0262408 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0261926 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0261111 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0260693 |
| TLE4 | transducin-like enhancer of split 4 | 0.0260091 |
| UGP2 | UDP-glucose pyrophosphorylase 2 | 0.0259287 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0258569 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0258328 |
| B2M | beta-2-microglobulin | 0.0257444 |
| ZNF638 | zinc finger protein 638 | 0.025588 |
| GPHN | gephyrin | 0.0251503 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0251108 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0250348 |
| EFCAB13 | EF-hand calcium binding domain 13 | 0.0246438 |
| BRD2 | bromodomain containing 2 | 0.0244799 |
| EFNA5 | ephrin-A5 | 0.0244308 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0243846 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 0.0241272 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0241124 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.0240965 |
| ZFP36 | ZFP36 ring finger protein | 0.023969 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0234991 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0233167 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0232624 |
| SQSTM1 | sequestosome 1 | 0.0230222 |
| ABHD17C | abhydrolase domain containing 17C | 0.022963 |
| FOSL1 | FOS-like antigen 1 | 0.0227901 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0226977 |
| FMNL2 | formin-like 2 | 0.0225424 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0223274 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0223139 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0221663 |
| ANXA5 | annexin A5 | 0.0214075 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0213959 |
| MCL1 | myeloid cell leukemia 1 | 0.0212697 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0209591 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0208991 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0208891 |
| MYO9B | myosin IXB | 0.0208296 |
| JMJD1C | jumonji domain containing 1C | 0.020804 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | 0.0207702 |
| CRYBG3 | beta-gamma crystallin domain containing 3 | 0.0207465 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | 0.0207369 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.159323 |
| VGF | VGF nerve growth factor inducible | -0.146936 |
| DCT | dopachrome tautomerase | -0.117262 |
| HMCN1 | hemicentin 1 | -0.0917012 |
| NDRG1 | N-myc downstream regulated 1 | -0.0869353 |
| FN1 | fibronectin 1 | -0.0859623 |
| FMN1 | formin 1 | -0.081064 |
| GDF15 | growth differentiation factor 15 | -0.0795197 |
| TMEM123 | transmembrane protein 123 | -0.0759666 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0704022 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.066354 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0643808 |
| CDK14 | cyclin-dependent kinase 14 | -0.0623594 |
| PGK1 | phosphoglycerate kinase 1 | -0.05924 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0591803 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.057222 |
| TMSB10 | thymosin beta 10 | -0.0571969 |
| CALD1 | caldesmon 1 | -0.0561101 |
| PKM | pyruvate kinase, muscle | -0.0555134 |
| CDC73 | cell division cycle 73 | -0.0542266 |
| TNNC1 | troponin C type 1 (slow) | -0.0538205 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0533985 |
| COL19A1 | collagen, type XIX, alpha 1 | -0.0517334 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0501817 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0486572 |
| EHBP1 | EH domain binding protein 1 | -0.0484717 |
| PDE10A | phosphodiesterase 10A | -0.0480501 |
| RUNX1 | runt-related transcription factor 1 | -0.0475703 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0457001 |
| C10ORF90 | chromosome 10 open reading frame 90 | -0.045415 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0448087 |
| SCFD2 | sec1 family domain containing 2 | -0.0445993 |
| NAV2 | neuron navigator 2 | -0.0444874 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0438249 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0434255 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | -0.0419548 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | -0.041392 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | -0.0407009 |
| SBF2 | SET binding factor 2 | -0.0379668 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | -0.0378204 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0365992 |
| WDR45B | WD repeat domain 45B | -0.0365687 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0359662 |
| NPR2 | natriuretic peptide receptor 2 | -0.0358821 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0354232 |
| ICAM1 | intercellular adhesion molecule 1 | -0.034775 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0345046 |
| NAV3 | neuron navigator 3 | -0.0338227 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | -0.0325823 |
| PTCHD4 | patched domain containing 4 | -0.0322905 |
| NBAS | neuroblastoma amplified sequence | -0.03228 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0321979 |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) | -0.0320475 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.031757 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.0313533 |
| PTK2 | protein tyrosine kinase 2 | -0.0312961 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.030711 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0303827 |
| INSIG2 | insulin induced gene 2 | -0.0302128 |
| GHR | growth hormone receptor | -0.0300613 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0297562 |
| NRCAM | neuronal cell adhesion molecule | -0.0297061 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | -0.0294149 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0294143 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0293683 |
| JAZF1 | JAZF zinc finger 1 | -0.0292854 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | -0.0277049 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0276288 |
| FLNA | filamin A, alpha | -0.0275928 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0274684 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0274652 |
| CD109 | CD109 molecule | -0.027422 |
| SRPK2 | SRSF protein kinase 2 | -0.0271334 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0270437 |
| EBF1 | early B-cell factor 1 | -0.0269361 |
| BSG | basigin (Ok blood group) | -0.0269259 |
| OXR1 | oxidation resistance 1 | -0.026665 |
| UBE3C | ubiquitin protein ligase E3C | -0.0263212 |
| APP | amyloid beta (A4) precursor protein | -0.02561 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0253471 |
| TAGLN2 | transgelin 2 | -0.0250647 |
| RNF213 | ring finger protein 213 | -0.0250579 |
| ITGB8 | integrin, beta 8 | -0.0249518 |
| RBM33 | RNA binding motif protein 33 | -0.0247833 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.024759 |
| POTEF | POTE ankyrin domain family, member F | -0.0246036 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0240669 |
| HBP1 | HMG-box transcription factor 1 | -0.0239836 |
| RNF145 | ring finger protein 145 | -0.0239477 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0237585 |
| TAC4 | tachykinin 4 (hemokinin) | -0.0233172 |
| AHCYL2 | adenosylhomocysteinase-like 2 | -0.0232838 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0232246 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0230431 |
| HELZ | helicase with zinc finger | -0.0230341 |
| COL1A2 | collagen, type I, alpha 2 | -0.0228269 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | -0.0227145 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0225387 |
| FIP1L1 | factor interacting with PAPOLA and CPSF1 | -0.0223676 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0220987 |