| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Azithromycin (hydrate) perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Azithromycin (hydrate)_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.104573 |
| MT2A | metallothionein 2A | 0.100328 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0574562 |
| VMP1 | vacuole membrane protein 1 | 0.0553444 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0485082 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0474725 |
| TXNIP | thioredoxin interacting protein | 0.047196 |
| RPS12 | ribosomal protein S12 | 0.0432936 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.042392 |
| RPL23 | ribosomal protein L23 | 0.0422179 |
| APOL1 | apolipoprotein L, 1 | 0.0409174 |
| LAMA4 | laminin, alpha 4 | 0.0406891 |
| GOLGB1 | golgin B1 | 0.0394543 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0375893 |
| RPS2 | ribosomal protein S2 | 0.036693 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0342602 |
| CSTB | cystatin B (stefin B) | 0.0341548 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0322978 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0321346 |
| RPL11 | ribosomal protein L11 | 0.0313125 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0301689 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0298087 |
| LCN2 | lipocalin 2 | 0.0293228 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0282927 |
| RPS8 | ribosomal protein S8 | 0.0271617 |
| LAMB3 | laminin, beta 3 | 0.0248336 |
| TMF1 | TATA element modulatory factor 1 | 0.0247931 |
| AREG | amphiregulin | 0.0242896 |
| PHF3 | PHD finger protein 3 | 0.0237735 |
| SMAD3 | SMAD family member 3 | 0.0237454 |
| GOLM2 | golgi membrane protein 2 | 0.0235442 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0234598 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0230504 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0228001 |
| ANGPTL4 | angiopoietin-like 4 | 0.022486 |
| RPL21 | ribosomal protein L21 | 0.0220416 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0218631 |
| RPS3 | ribosomal protein S3 | 0.0216499 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0215966 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0214642 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0211027 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.020867 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0208298 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0200794 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0199378 |
| KLF6 | Kruppel-like factor 6 | 0.0198413 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0198396 |
| GPATCH2L | G patch domain containing 2-like | 0.0198284 |
| ANO6 | anoctamin 6 | 0.0197552 |
| RPS7 | ribosomal protein S7 | 0.019729 |
| MCL1 | myeloid cell leukemia 1 | 0.0196588 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.0196116 |
| SGMS2 | sphingomyelin synthase 2 | 0.0193963 |
| ADAM28 | ADAM metallopeptidase domain 28 | 0.0193705 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0190136 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0189936 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0189843 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0187574 |
| TMEM51 | transmembrane protein 51 | 0.0185315 |
| GOLGA4 | golgin A4 | 0.0181873 |
| BARX2 | BARX homeobox 2 | 0.0181647 |
| SACK1A | scaffolding CK1 anchoring protein A | 0.0172709 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0171903 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0170489 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0166442 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0166161 |
| BLZF1 | basic leucine zipper nuclear factor 1 | 0.0165686 |
| C15ORF48 | chromosome 15 open reading frame 48 | 0.0164324 |
| RPS25 | ribosomal protein S25 | 0.0157461 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0157284 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0155827 |
| TMCC3 | transmembrane and coiled-coil domain family 3 | 0.0155651 |
| DUSP5 | dual specificity phosphatase 5 | 0.0153358 |
| SON | SON DNA binding protein | 0.0152878 |
| DSCAM | Down syndrome cell adhesion molecule | 0.015172 |
| RPL37A | ribosomal protein L37a | 0.0150529 |
| RSRP1 | arginine/serine-rich protein 1 | 0.0150242 |
| DUOX2 | dual oxidase 2 | 0.01476 |
| CD58 | CD58 molecule | 0.0146897 |
| FAM110C | family with sequence similarity 110, member C | 0.014535 |
| SRSF5 | serine/arginine-rich splicing factor 5 | 0.0144153 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0142709 |
| REST | RE1-silencing transcription factor | 0.0136232 |
| IFI44L | interferon-induced protein 44-like | 0.0136203 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.013135 |
| ZFP36 | ZFP36 ring finger protein | 0.0129237 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0128696 |
| MPZL2 | myelin protein zero-like 2 | 0.0128551 |
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 | 0.0124548 |
| RPL12 | ribosomal protein L12 | 0.0124184 |
| H1-2 | H1.2 linker histone, cluster member | 0.0122848 |
| AFDN | afadin, adherens junction formation factor | 0.0122183 |
| ZC3H12C | zinc finger CCCH-type containing 12C | 0.0122096 |
| WDR26 | WD repeat domain 26 | 0.0121765 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0120663 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0118618 |
| WDPCP | WD repeat containing planar cell polarity effector | 0.0118371 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | 0.0118163 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.0118131 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0117441 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.244568 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.208657 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.149324 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.146648 |
| PTMA | prothymosin, alpha | -0.13917 |
| TMSB4X | thymosin beta 4, X-linked | -0.109759 |
| MMP7 | matrix metallopeptidase 7 | -0.107293 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.104841 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.10468 |
| PKM | pyruvate kinase, muscle | -0.0959281 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0953991 |
| S100A6 | S100 calcium binding protein A6 | -0.0904406 |
| CP | ceruloplasmin (ferroxidase) | -0.088502 |
| POTEF | POTE ankyrin domain family, member F | -0.0875766 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0841274 |
| ACTG1 | actin gamma 1 | -0.0806039 |
| PARD3 | par-3 family cell polarity regulator | -0.078696 |
| MUC4 | mucin 4, cell surface associated | -0.078185 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0778141 |
| RNF213 | ring finger protein 213 | -0.0754057 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0730831 |
| VIM | vimentin | -0.0726987 |
| HLA-A | major histocompatibility complex, class I, A | -0.0716554 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0698431 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0682893 |
| PGK1 | phosphoglycerate kinase 1 | -0.0654461 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0647458 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0624048 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0623898 |
| EZR | ezrin | -0.0620328 |
| ANXA2 | annexin A2 | -0.0619542 |
| ACTN4 | actinin, alpha 4 | -0.060038 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0596242 |
| LMO7 | LIM domain 7 | -0.0590432 |
| HMGA1 | high mobility group AT-hook 1 | -0.0588563 |
| HLA-B | major histocompatibility complex, class I, B | -0.0568528 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0561771 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0561493 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0537691 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0531748 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0527012 |
| RPL35A | ribosomal protein L35a | -0.0526739 |
| ASPH | aspartate beta-hydroxylase | -0.0520631 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0512442 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0510988 |
| AHNAK | AHNAK nucleoprotein | -0.0498923 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0492905 |
| DTNA | dystrobrevin, alpha | -0.0491736 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0491535 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0480892 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0479902 |
| CDK6 | cyclin-dependent kinase 6 | -0.0479872 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0474499 |
| PCDH7 | protocadherin 7 | -0.047273 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0468962 |
| APP | amyloid beta (A4) precursor protein | -0.046793 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0463023 |
| PLAU | plasminogen activator, urokinase | -0.0459717 |
| RPLP1 | ribosomal protein, large, P1 | -0.0456829 |
| SPAG9 | sperm associated antigen 9 | -0.0454287 |
| TPM1 | tropomyosin 1 (alpha) | -0.0446917 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0445822 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0439044 |
| RCOR1 | REST corepressor 1 | -0.043213 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0430165 |
| TMEM123 | transmembrane protein 123 | -0.0428685 |
| GRB10 | growth factor receptor-bound protein 10 | -0.042778 |
| TAPBP | TAP binding protein (tapasin) | -0.0426603 |
| PRKCA | protein kinase C, alpha | -0.042501 |
| INSIG1 | insulin induced gene 1 | -0.0418967 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0411229 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0405234 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0400626 |
| FLNB | filamin B, beta | -0.0396495 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0393865 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | -0.0392576 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0390955 |
| RTN4 | reticulon 4 | -0.0390746 |
| NCKAP5 | NCK-associated protein 5 | -0.0385606 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0383961 |
| GNAS | GNAS complex locus | -0.0382935 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0378856 |
| TPM4 | tropomyosin 4 | -0.0374768 |
| ITGA6 | integrin, alpha 6 | -0.0374046 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0371415 |
| CCNY | cyclin Y | -0.0367704 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0362838 |
| DST | dystonin | -0.0362209 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0360588 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0355055 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.034406 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0343534 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.034011 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | -0.0339705 |
| ANXA11 | annexin A11 | -0.0339523 |
| LMNA | lamin A/C | -0.0338877 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.033741 |
| RASAL2 | RAS protein activator like 2 | -0.0333121 |
| AFF4 | AF4/FMR2 family, member 4 | -0.03328 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0332213 |