| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Azithromycin (hydrate) perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Azithromycin (hydrate)_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| STS | steroid sulfatase (microsomal), isozyme S | 0.127898 |
| LCN2 | lipocalin 2 | 0.12001 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.119552 |
| C6ORF132 | chromosome 6 open reading frame 132 | 0.117935 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.111159 |
| VMP1 | vacuole membrane protein 1 | 0.104383 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.08594 |
| SMAD3 | SMAD family member 3 | 0.0827368 |
| TXNIP | thioredoxin interacting protein | 0.0810933 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0807349 |
| BCL2L1 | BCL2-like 1 | 0.0783222 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0770892 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0769474 |
| LIMA1 | LIM domain and actin binding 1 | 0.0760616 |
| FNDC3B | fibronectin type III domain containing 3B | 0.074434 |
| ASPH | aspartate beta-hydroxylase | 0.0740846 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0720101 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0658399 |
| AREG | amphiregulin | 0.065537 |
| EFNB2 | ephrin-B2 | 0.0626949 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0617368 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0608717 |
| B2M | beta-2-microglobulin | 0.0586357 |
| MX2 | MX dynamin-like GTPase 2 | 0.0578181 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0574839 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0573446 |
| ERBIN | erbb2 interacting protein | 0.056694 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0543533 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0541587 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0539154 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0529044 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.05218 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | 0.0514413 |
| MX1 | MX dynamin-like GTPase 1 | 0.0513752 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0511337 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0499881 |
| TSHZ2 | teashirt zinc finger homeobox 2 | 0.0488947 |
| ENO1 | enolase 1, (alpha) | 0.0482133 |
| FAT1 | FAT atypical cadherin 1 | 0.0479029 |
| DIAPH1 | diaphanous-related formin 1 | 0.0475128 |
| DST | dystonin | 0.0472586 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0464836 |
| ETV6 | ets variant 6 | 0.0464001 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0452738 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.044645 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0441248 |
| IFNGR1 | interferon gamma receptor 1 | 0.0437845 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0420349 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0419151 |
| MT2A | metallothionein 2A | 0.0418513 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0417388 |
| BICRAL | BICRA like chromatin remodeling complex associated protein | 0.0417277 |
| UBC | ubiquitin C | 0.0416651 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0415941 |
| STK24 | serine/threonine kinase 24 | 0.0408725 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0406621 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0405235 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0402999 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0400752 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0395486 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0392378 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0383629 |
| FRMD5 | FERM domain containing 5 | 0.0381375 |
| ATP10B | ATPase, class V, type 10B | 0.0379955 |
| RPL23 | ribosomal protein L23 | 0.0378547 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0375711 |
| JMJD1C | jumonji domain containing 1C | 0.0370418 |
| LMO7 | LIM domain 7 | 0.0367631 |
| MEF2A | myocyte enhancer factor 2A | 0.0366373 |
| PGK1 | phosphoglycerate kinase 1 | 0.0365191 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0362766 |
| TRERF1 | transcriptional regulating factor 1 | 0.0361854 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.0361457 |
| TMC5 | transmembrane channel-like 5 | 0.0359655 |
| PARD3 | par-3 family cell polarity regulator | 0.0354513 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.03415 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0341199 |
| RBM47 | RNA binding motif protein 47 | 0.0338931 |
| SH3PXD2A | SH3 and PX domains 2A | 0.0335157 |
| EFNA5 | ephrin-A5 | 0.0335113 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0327818 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0327221 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0327213 |
| MAP7 | microtubule-associated protein 7 | 0.0326887 |
| TPM3 | tropomyosin 3 | 0.0323744 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0322571 |
| PTGR1 | prostaglandin reductase 1 | 0.0321872 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0320906 |
| MYO1E | myosin IE | 0.0319229 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0319059 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0316879 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0315338 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0312601 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0309016 |
| APOL1 | apolipoprotein L, 1 | 0.0307809 |
| FTL | ferritin, light polypeptide | 0.030641 |
| YAP1 | Yes-associated protein 1 | 0.0302264 |
| DGKH | diacylglycerol kinase, eta | 0.0300275 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0299466 |
| CUX1 | cut-like homeobox 1 | 0.0297886 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.180358 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.155918 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.117162 |
| EGR1 | early growth response 1 | -0.0904101 |
| SQSTM1 | sequestosome 1 | -0.0902243 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0780816 |
| MORF4L2 | mortality factor 4 like 2 | -0.0647305 |
| H1-0 | H1.0 linker histone | -0.0641546 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0624721 |
| HDLBP | high density lipoprotein binding protein | -0.0612156 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0603873 |
| HLA-B | major histocompatibility complex, class I, B | -0.0603611 |
| IRF1 | interferon regulatory factor 1 | -0.0591401 |
| RUNX1 | runt-related transcription factor 1 | -0.0554007 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0531136 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0523577 |
| GOLGB1 | golgin B1 | -0.05171 |
| NDRG1 | N-myc downstream regulated 1 | -0.0512299 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0503828 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0476276 |
| INTS6 | integrator complex subunit 6 | -0.0472293 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0468467 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0462958 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0433731 |
| AGR2 | anterior gradient 2 | -0.0433052 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0429198 |
| LYZ | lysozyme | -0.042885 |
| FNIP1 | folliculin interacting protein 1 | -0.0428796 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0428229 |
| ADIPOR2 | adiponectin receptor 2 | -0.0426123 |
| AHI1 | Abelson helper integration site 1 | -0.0422545 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0421576 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0415016 |
| DIAPH3 | diaphanous-related formin 3 | -0.0409849 |
| SEC24D | SEC24 family member D | -0.0404848 |
| CLTC | clathrin, heavy chain (Hc) | -0.0403861 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0387644 |
| RRBP1 | ribosome binding protein 1 | -0.0387029 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0385116 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.0383702 |
| ARF1 | ADP-ribosylation factor 1 | -0.03807 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0379684 |
| COPA | coatomer protein complex, subunit alpha | -0.0378024 |
| MKI67 | marker of proliferation Ki-67 | -0.037707 |
| CANX | calnexin | -0.0373338 |
| PPARGC1A | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha | -0.0371358 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0369513 |
| UFM1 | ubiquitin-fold modifier 1 | -0.0366495 |
| COG6 | component of oligomeric golgi complex 6 | -0.0364208 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0363419 |
| PMM2 | phosphomannomutase 2 | -0.0362095 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0352807 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0351803 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0347404 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0344465 |
| RBM39 | RNA binding motif protein 39 | -0.0344338 |
| SPATA13 | spermatogenesis associated 13 | -0.0344255 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0339521 |
| SEC24A | SEC24 family member A | -0.0337729 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0334918 |
| CENPF | centromere protein F, 350/400kDa | -0.0334362 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | -0.0333013 |
| NUCB2 | nucleobindin 2 | -0.033288 |
| HM13 | histocompatibility (minor) 13 | -0.0331198 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | -0.0318146 |
| HLA-E | major histocompatibility complex, class I, E | -0.0316659 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 | -0.0313876 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | -0.0312515 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.0309409 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0307771 |
| TMEM263 | transmembrane protein 263 | -0.0307447 |
| ARF4 | ADP-ribosylation factor 4 | -0.0307354 |
| CALR | calreticulin | -0.030677 |
| HLA-C | major histocompatibility complex, class I, C | -0.0302988 |
| ERLEC1 | endoplasmic reticulum lectin 1 | -0.0293938 |
| BRCA2 | breast cancer 2, early onset | -0.02925 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0292042 |
| GOLGA2 | golgin A2 | -0.02867 |
| CCNL1 | cyclin L1 | -0.02838 |
| CALU | calumenin | -0.0282966 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0279761 |
| WDR45B | WD repeat domain 45B | -0.027958 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0278279 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0277913 |
| HBS1L | HBS1-like translational GTPase | -0.027777 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0275348 |
| TFRC | transferrin receptor | -0.0273286 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0272853 |
| PRRC1 | proline-rich coiled-coil 1 | -0.0271369 |
| MSMO1 | methylsterol monooxygenase 1 | -0.0264523 |
| PTEN | phosphatase and tensin homolog | -0.0261068 |
| FDPS | farnesyl diphosphate synthase | -0.0259521 |
| SAR1A | secretion associated, Ras related GTPase 1A | -0.0259335 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0258911 |
| HDAC4 | histone deacetylase 4 | -0.0258261 |
| NPSR1 | neuropeptide S receptor 1 | -0.0257284 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0256402 |
| SERINC5 | serine incorporator 5 | -0.0256271 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | -0.025491 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | -0.0253434 |
