| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Azithromycin (hydrate) perturbation in HCT15 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Azithromycin (hydrate)_HCT15 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.185144 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.16158 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.152718 |
| TXNIP | thioredoxin interacting protein | 0.0956517 |
| MT2A | metallothionein 2A | 0.0922486 |
| GOLGA4 | golgin A4 | 0.0854202 |
| RPS6 | ribosomal protein S6 | 0.0819018 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.081108 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0790927 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.071643 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0605926 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0590934 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0581379 |
| RPL21 | ribosomal protein L21 | 0.0501877 |
| DSPP | dentin sialophosphoprotein | 0.0487332 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0477999 |
| ZNF638 | zinc finger protein 638 | 0.0468767 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0428336 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0418092 |
| RPS12 | ribosomal protein S12 | 0.0417606 |
| VMP1 | vacuole membrane protein 1 | 0.0412017 |
| PCBP2 | poly(rC) binding protein 2 | 0.0396698 |
| H1-4 | H1.4 linker histone, cluster member | 0.0392535 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0390599 |
| H1-2 | H1.2 linker histone, cluster member | 0.0386175 |
| GOLGB1 | golgin B1 | 0.0382054 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0379196 |
| ENO1 | enolase 1, (alpha) | 0.0378945 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0374052 |
| TPI1 | triosephosphate isomerase 1 | 0.0373876 |
| PRELID2 | PRELI domain containing 2 | 0.0369081 |
| RPS2 | ribosomal protein S2 | 0.0363562 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0363259 |
| TMF1 | TATA element modulatory factor 1 | 0.0349718 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0336829 |
| CLU | clusterin | 0.0336297 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0333753 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0322488 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0316258 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0314191 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.030757 |
| XRN1 | 5'-3' exoribonuclease 1 | 0.030604 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0304171 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0300888 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0295786 |
| SETD5 | SET domain containing 5 | 0.028812 |
| RPL23 | ribosomal protein L23 | 0.0278683 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0278564 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.0277312 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0276175 |
| SUPT16H | suppressor of Ty 16 homolog (S. cerevisiae) | 0.0275882 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0274799 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0269457 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0266069 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0265736 |
| S100A9 | S100 calcium binding protein A9 | 0.0264966 |
| SMC5 | structural maintenance of chromosomes 5 | 0.0262679 |
| SON | SON DNA binding protein | 0.0260951 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0259667 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0256753 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0254267 |
| RPL18 | ribosomal protein L18 | 0.0253838 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0253561 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0253383 |
| BPTF | bromodomain PHD finger transcription factor | 0.0251124 |
| BBX | bobby sox homolog (Drosophila) | 0.0249909 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 | 0.0248772 |
| ASPH | aspartate beta-hydroxylase | 0.0246743 |
| ZFP36 | ZFP36 ring finger protein | 0.0245925 |
| KIF1B | kinesin family member 1B | 0.0239578 |
| ATP13A3 | ATPase type 13A3 | 0.0239353 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0239044 |
| MCL1 | myeloid cell leukemia 1 | 0.0237648 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0236049 |
| SQSTM1 | sequestosome 1 | 0.0236 |
| SCAPER | S-phase cyclin A-associated protein in the ER | 0.0234974 |
| AKAP10 | A kinase (PRKA) anchor protein 10 | 0.0232459 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0231378 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0229989 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0229871 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0226801 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0226728 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0226285 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.0226064 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0224627 |
| KLF6 | Kruppel-like factor 6 | 0.0222645 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0222566 |
| SERF2 | small EDRK-rich factor 2 | 0.0221647 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0218857 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0215267 |
| ZC3H13 | zinc finger CCCH-type containing 13 | 0.0211382 |
| MACROD2 | MACRO domain containing 2 | 0.0210479 |
| AHCYL1 | adenosylhomocysteinase-like 1 | 0.0210384 |
| KDELR1 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 | 0.0210219 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0209012 |
| MIDN | midnolin | 0.0207531 |
| RPL36 | ribosomal protein L36 | 0.0206201 |
| EHBP1 | EH domain binding protein 1 | 0.0204063 |
| RNF24 | ring finger protein 24 | 0.0202546 |
| SRSF4 | serine/arginine-rich splicing factor 4 | 0.020182 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FAT1 | FAT atypical cadherin 1 | -0.2061 |
| PTMA | prothymosin, alpha | -0.144631 |
| NDRG1 | N-myc downstream regulated 1 | -0.134665 |
| LOC112694756 | uncharaterized LOC112694756 | -0.102266 |
| AHNAK | AHNAK nucleoprotein | -0.0901839 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0860972 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0709924 |
| PKM | pyruvate kinase, muscle | -0.0611481 |
| RPL35A | ribosomal protein L35a | -0.0565041 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.055659 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0552376 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0547103 |
| CCND1 | cyclin D1 | -0.0540594 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0519724 |
| ACTN4 | actinin, alpha 4 | -0.0474951 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0474515 |
| KRT8 | keratin 8, type II | -0.046248 |
| TMSB10 | thymosin beta 10 | -0.0461263 |
| RPL4 | ribosomal protein L4 | -0.0450468 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.044162 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0435428 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0427513 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0405302 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0399691 |
| RPLP0 | ribosomal protein, large, P0 | -0.0397822 |
| HMGA2 | high mobility group AT-hook 2 | -0.0393231 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0391719 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0385772 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0382423 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0382185 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0380004 |
| MED13L | mediator complex subunit 13-like | -0.0378271 |
| SCARB1 | scavenger receptor class B, member 1 | -0.0364827 |
| HMGA1 | high mobility group AT-hook 1 | -0.0362017 |
| ITGB4 | integrin, beta 4 | -0.0359775 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0357896 |
| HLA-A | major histocompatibility complex, class I, A | -0.0357687 |
| TPM4 | tropomyosin 4 | -0.0353735 |
| FHIT | fragile histidine triad | -0.035005 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0347779 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0346484 |
| PGK1 | phosphoglycerate kinase 1 | -0.0345724 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0344094 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0342899 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0341045 |
| HOOK2 | hook microtubule-tethering protein 2 | -0.0337789 |
| CBX3 | chromobox homolog 3 | -0.0334504 |
| PLEC | plectin | -0.0333801 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0333788 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0331461 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0329567 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.0328824 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0326473 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0323297 |
| SH3BP4 | SH3-domain binding protein 4 | -0.0321263 |
| ANXA2 | annexin A2 | -0.0317056 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 | -0.031646 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0314655 |
| ARF4 | ADP-ribosylation factor 4 | -0.0310765 |
| NPR2 | natriuretic peptide receptor 2 | -0.030125 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0293816 |
| FLNB | filamin B, beta | -0.0292385 |
| YEATS2 | YEATS domain containing 2 | -0.0289576 |
| FLNA | filamin A, alpha | -0.0288849 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.028757 |
| YBX1 | Y box binding protein 1 | -0.0286981 |
| TXNRD1 | thioredoxin reductase 1 | -0.0285092 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0284629 |
| RPS24 | ribosomal protein S24 | -0.0284152 |
| ARF1 | ADP-ribosylation factor 1 | -0.028352 |
| CELF1 | CUGBP, Elav-like family member 1 | -0.0275364 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.027531 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0275087 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.026893 |
| HOXB3 | homeobox B3 | -0.026871 |
| SERINC5 | serine incorporator 5 | -0.0268476 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0266872 |
| RREB1 | ras responsive element binding protein 1 | -0.0265803 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0265322 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0261212 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.0258677 |
| PERP | PERP, TP53 apoptosis effector | -0.02581 |
| RBM25 | RNA binding motif protein 25 | -0.0254312 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.0250705 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | -0.0249437 |
| LMNA | lamin A/C | -0.0246527 |
| RNF213 | ring finger protein 213 | -0.0245972 |
| TMEM123 | transmembrane protein 123 | -0.0245345 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0244958 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0244104 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | -0.0243129 |
| NOP58 | NOP58 ribonucleoprotein | -0.0242355 |
| UBE2I | ubiquitin-conjugating enzyme E2I | -0.0240422 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0237672 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.023634 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.0235329 |
| R3HDM1 | R3H domain containing 1 | -0.023448 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0234085 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0233008 |
| RNF43 | ring finger protein 43 | -0.0232369 |
