| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Azithromycin (hydrate) perturbation in HEC-1-A cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Azithromycin (hydrate)_HEC-1-A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GOLGA4 | golgin A4 | 0.0896279 |
| RPS12 | ribosomal protein S12 | 0.0769107 |
| RPS2 | ribosomal protein S2 | 0.0689058 |
| RPS8 | ribosomal protein S8 | 0.0658427 |
| MT2A | metallothionein 2A | 0.0653091 |
| RPS6 | ribosomal protein S6 | 0.0616144 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0534466 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0523757 |
| VMP1 | vacuole membrane protein 1 | 0.0497573 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0465034 |
| B2M | beta-2-microglobulin | 0.0453797 |
| MKI67 | marker of proliferation Ki-67 | 0.0452241 |
| SET | SET nuclear proto-oncogene | 0.0429097 |
| H1-4 | H1.4 linker histone, cluster member | 0.0395335 |
| RPL23 | ribosomal protein L23 | 0.0392244 |
| SETD5 | SET domain containing 5 | 0.0378883 |
| MACROD2 | MACRO domain containing 2 | 0.0378174 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0376215 |
| KIF5B | kinesin family member 5B | 0.0368432 |
| RPS19 | ribosomal protein S19 | 0.036711 |
| RPL11 | ribosomal protein L11 | 0.0366929 |
| TMF1 | TATA element modulatory factor 1 | 0.0366713 |
| SNX9 | sorting nexin 9 | 0.0362692 |
| OGA | O-GlcNAcase | 0.0351171 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0337008 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0328121 |
| XPO1 | exportin 1 | 0.0325443 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0324433 |
| OPTN | optineurin | 0.0323893 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0323427 |
| RPL21 | ribosomal protein L21 | 0.0323394 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0323084 |
| H1-2 | H1.2 linker histone, cluster member | 0.0321102 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | 0.0315361 |
| TMA7 | translation machinery associated 7 homolog (S. cerevisiae) | 0.0312406 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0308073 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0307696 |
| ZNF292 | zinc finger protein 292 | 0.0300007 |
| RPS29 | ribosomal protein S29 | 0.0299801 |
| DSG2 | desmoglein 2 | 0.0299399 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0292901 |
| WAC | WW domain containing adaptor with coiled-coil | 0.028947 |
| RPL12 | ribosomal protein L12 | 0.0286892 |
| RPLP2 | ribosomal protein, large, P2 | 0.0286612 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0284934 |
| GOLM2 | golgi membrane protein 2 | 0.02843 |
| RPS7 | ribosomal protein S7 | 0.0279366 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0275039 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0273995 |
| RPS3 | ribosomal protein S3 | 0.0270808 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0269484 |
| TPR | translocated promoter region, nuclear basket protein | 0.0268868 |
| PNN | pinin, desmosome associated protein | 0.0266466 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0263353 |
| RPL26 | ribosomal protein L26 | 0.0263255 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0263038 |
| RBM5 | RNA binding motif protein 5 | 0.0262946 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0262571 |
| HLTF | helicase-like transcription factor | 0.0261776 |
| CIP2A | cellular inhibitor of PP2A | 0.0258534 |
| VEZT | vezatin, adherens junctions transmembrane protein | 0.0257887 |
| RPL36 | ribosomal protein L36 | 0.0257257 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0255248 |
| RPL28 | ribosomal protein L28 | 0.0254516 |
| RPL18 | ribosomal protein L18 | 0.0253294 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.0245895 |
| XRN1 | 5'-3' exoribonuclease 1 | 0.0243327 |
| REST | RE1-silencing transcription factor | 0.0238469 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0234444 |
| RPL35 | ribosomal protein L35 | 0.0233612 |
| SRSF4 | serine/arginine-rich splicing factor 4 | 0.0231005 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0228631 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0226908 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0224928 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0223952 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0223292 |
| KIAA1328 | KIAA1328 | 0.0222362 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.021703 |
| RNF145 | ring finger protein 145 | 0.0215112 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0214557 |
| CEP290 | centrosomal protein 290kDa | 0.021437 |
| EXOC6B | exocyst complex component 6B | 0.0211768 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.0211228 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0209337 |
| TPI1 | triosephosphate isomerase 1 | 0.020826 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0205989 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0205497 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | 0.0204946 |
| RIOK3 | RIO kinase 3 | 0.0204352 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0204023 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0203743 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0203467 |
| RPS27A | ribosomal protein S27a | 0.0201675 |
| BCL2L1 | BCL2-like 1 | 0.019991 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0199595 |
| KIF18B | kinesin family member 18B | 0.0198154 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0198102 |
| RPS25 | ribosomal protein S25 | 0.0197867 |
| SON | SON DNA binding protein | 0.0197262 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0195711 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.127964 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.119833 |
| NDRG1 | N-myc downstream regulated 1 | -0.116729 |
| PAX8 | paired box 8 | -0.110257 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.102353 |
| ANXA2 | annexin A2 | -0.0964753 |
| EGFR | epidermal growth factor receptor | -0.088727 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0882931 |
| FLNB | filamin B, beta | -0.086889 |
| AHNAK | AHNAK nucleoprotein | -0.0828051 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0781828 |
| FLNA | filamin A, alpha | -0.0779844 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0776642 |
| LDHA | lactate dehydrogenase A | -0.077384 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0757074 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0725615 |
| KRT7 | keratin 7, type II | -0.0724463 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0711982 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0705572 |
| CD44 | CD44 molecule (Indian blood group) | -0.0701658 |
| ACTN4 | actinin, alpha 4 | -0.0694163 |
| CCND1 | cyclin D1 | -0.0680625 |
| TMSB4X | thymosin beta 4, X-linked | -0.0677286 |
| ITGB8 | integrin, beta 8 | -0.0667328 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0633405 |
| HMGA1 | high mobility group AT-hook 1 | -0.0625089 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0598082 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0595146 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0579343 |
| CREB5 | cAMP responsive element binding protein 5 | -0.0564141 |
| APP | amyloid beta (A4) precursor protein | -0.055294 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | -0.054377 |
| MYOF | myoferlin | -0.0542629 |
| RNF213 | ring finger protein 213 | -0.0539797 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0522925 |
| PKM | pyruvate kinase, muscle | -0.0512172 |
| LAMA4 | laminin, alpha 4 | -0.0491291 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0483242 |
| ASPH | aspartate beta-hydroxylase | -0.0482311 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0479419 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 | -0.0477453 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0474624 |
| TBC1D22A | TBC1 domain family, member 22A | -0.046461 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.045839 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0454502 |
| DSCAML1 | Down syndrome cell adhesion molecule like 1 | -0.0450051 |
| SVIL | supervillin | -0.0447595 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0446335 |
| KRT19 | keratin 19, type I | -0.0441665 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0438162 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0435097 |
| HMGA2 | high mobility group AT-hook 2 | -0.0428369 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0428032 |
| INTS6 | integrator complex subunit 6 | -0.0424352 |
| ANXA1 | annexin A1 | -0.041534 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0410482 |
| GPR39 | G protein-coupled receptor 39 | -0.0409694 |
| RUNX1 | runt-related transcription factor 1 | -0.0409185 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0400116 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0399276 |
| RPL35A | ribosomal protein L35a | -0.0398605 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0393198 |
| PLEC | plectin | -0.0391258 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | -0.0386413 |
| ANKRD11 | ankyrin repeat domain 11 | -0.038412 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0383514 |
| LAMC2 | laminin, gamma 2 | -0.0382692 |
| VCAN | versican | -0.0380186 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0378443 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0372121 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0368523 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.036789 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0365614 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.0364779 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0361108 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0357785 |
| DENND1A | DENN/MADD domain containing 1A | -0.0357772 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0357701 |
| POTEF | POTE ankyrin domain family, member F | -0.0354284 |
| EGR1 | early growth response 1 | -0.0350483 |
| FMNL2 | formin-like 2 | -0.03421 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0340217 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0338827 |
| ACTG1 | actin gamma 1 | -0.0336175 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0332842 |
| TNS3 | tensin 3 | -0.0331772 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0330736 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.032926 |
| WWC1 | WW and C2 domain containing 1 | -0.0327046 |
| ADAM32 | ADAM metallopeptidase domain 32 | -0.0326597 |
| PCED1B | PC-esterase domain containing 1B | -0.0326011 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0324673 |
| ATG7 | autophagy related 7 | -0.0324421 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.032167 |
| PDIA5 | protein disulfide isomerase family A, member 5 | -0.0320962 |
| PLCB4 | phospholipase C, beta 4 | -0.0320559 |
| EMP1 | epithelial membrane protein 1 | -0.0318808 |
| CTBP2 | C-terminal binding protein 2 | -0.0316482 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0315695 |
| HKDC1 | hexokinase domain containing 1 | -0.0310904 |
