| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Azithromycin (hydrate) perturbation in HOP62 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Azithromycin (hydrate)_HOP62 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CD44 | CD44 molecule (Indian blood group) | 0.12819 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.12584 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.123291 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.121879 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.113157 |
| ENO1 | enolase 1, (alpha) | 0.0766666 |
| HMGA2 | high mobility group AT-hook 2 | 0.0739417 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0736102 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0687361 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | 0.0666893 |
| STC1 | stanniocalcin 1 | 0.0655613 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0616122 |
| CDCP1 | CUB domain containing protein 1 | 0.0604402 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0601097 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0592714 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0588673 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0546658 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0527837 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.051569 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0507121 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0483161 |
| AXL | AXL receptor tyrosine kinase | 0.047827 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0428887 |
| GRAMD1B | GRAM domain containing 1B | 0.0425603 |
| MAP1B | microtubule-associated protein 1B | 0.0412249 |
| RAI14 | retinoic acid induced 14 | 0.0390478 |
| VCL | vinculin | 0.0379114 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0378696 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | 0.0374062 |
| MSN | moesin | 0.036672 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0361148 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0347287 |
| BPTF | bromodomain PHD finger transcription factor | 0.034227 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0316719 |
| ZNF638 | zinc finger protein 638 | 0.0304684 |
| CLIC4 | chloride intracellular channel 4 | 0.0303669 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0301139 |
| VIM | vimentin | 0.0298015 |
| TPM4 | tropomyosin 4 | 0.0296823 |
| WWOX | WW domain containing oxidoreductase | 0.029605 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0295209 |
| RRM2 | ribonucleotide reductase M2 | 0.0282893 |
| VMP1 | vacuole membrane protein 1 | 0.0280457 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.027799 |
| DNMBP | dynamin binding protein | 0.0274663 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0274055 |
| CAPRIN2 | caprin family member 2 | 0.0273101 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0272508 |
| RPS2 | ribosomal protein S2 | 0.0272374 |
| H1-2 | H1.2 linker histone, cluster member | 0.0259904 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0258918 |
| LDHA | lactate dehydrogenase A | 0.0257344 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0253849 |
| FOSL1 | FOS-like antigen 1 | 0.0247991 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0247947 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0247352 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0244956 |
| NAV1 | neuron navigator 1 | 0.0244378 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0243963 |
| NECTIN2 | nectin cell adhesion molecule 2 | 0.0243078 |
| VEGFC | vascular endothelial growth factor C | 0.0241367 |
| JAG1 | jagged 1 | 0.0237092 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0233309 |
| CLMP | CXADR-like membrane protein | 0.0232497 |
| LAMB3 | laminin, beta 3 | 0.0230803 |
| GOLGB1 | golgin B1 | 0.0230622 |
| ANXA5 | annexin A5 | 0.0229917 |
| AHNAK | AHNAK nucleoprotein | 0.0227576 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0227351 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0226963 |
| MYO10 | myosin X | 0.0226049 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0223546 |
| SVIL | supervillin | 0.0221753 |
| DSPP | dentin sialophosphoprotein | 0.0220791 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.021815 |
| NRDC | nardilysin convertase | 0.0217464 |
| MYO9B | myosin IXB | 0.021682 |
| MARK4 | MAP/microtubule affinity-regulating kinase 4 | 0.0216378 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0214191 |
| TPM3 | tropomyosin 3 | 0.0210799 |
| TPR | translocated promoter region, nuclear basket protein | 0.021042 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0210256 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0209715 |
| SMAD3 | SMAD family member 3 | 0.0208796 |
| ADAM19 | ADAM metallopeptidase domain 19 | 0.0207098 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0206354 |
| CD82 | CD82 molecule | 0.0205604 |
| CENPF | centromere protein F, 350/400kDa | 0.0205444 |
| TGM2 | transglutaminase 2 | 0.020506 |
| DCBLD1 | discoidin, CUB and LCCL domain containing 1 | 0.0204568 |
| ANXA2 | annexin A2 | 0.0203494 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.020131 |
| ECE1 | endothelin converting enzyme 1 | 0.0201276 |
| RPS12 | ribosomal protein S12 | 0.0197725 |
| MKI67 | marker of proliferation Ki-67 | 0.0196904 |
| SET | SET nuclear proto-oncogene | 0.019621 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0193233 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0193201 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0192469 |
| DEK | DEK proto-oncogene | 0.0191921 |
| Symbol | Name | Standardized Value |
|---|---|---|
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.192647 |
| CDH13 | cadherin 13 | -0.190345 |
| COL5A1 | collagen, type V, alpha 1 | -0.163614 |
| TMSB10 | thymosin beta 10 | -0.154064 |
| FN1 | fibronectin 1 | -0.129132 |
| FNDC3B | fibronectin type III domain containing 3B | -0.112677 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.10405 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0786855 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0713455 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0702879 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.066769 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0656058 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0605475 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0572269 |
| PDE10A | phosphodiesterase 10A | -0.0569661 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0533783 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0533574 |
| PTMA | prothymosin, alpha | -0.0522918 |
| IGF2 | insulin-like growth factor 2 | -0.0517496 |
| CD109 | CD109 molecule | -0.0512475 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0510805 |
| MT2A | metallothionein 2A | -0.0498218 |
| ASPH | aspartate beta-hydroxylase | -0.0493619 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0483442 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0478835 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0476008 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0475214 |
| FAM13A | family with sequence similarity 13, member A | -0.047413 |
| NDRG1 | N-myc downstream regulated 1 | -0.0454617 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0453784 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0438869 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0424762 |
| USP3 | ubiquitin specific peptidase 3 | -0.0399711 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0392139 |
| RUNX1 | runt-related transcription factor 1 | -0.0388747 |
| ZNF292 | zinc finger protein 292 | -0.0381462 |
| LOX | lysyl oxidase | -0.0376664 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0372731 |
| FLNA | filamin A, alpha | -0.0372177 |
| PCBP3 | poly(rC) binding protein 3 | -0.0370917 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0370669 |
| HELZ | helicase with zinc finger | -0.0360931 |
| ARF4 | ADP-ribosylation factor 4 | -0.0359659 |
| INSIG2 | insulin induced gene 2 | -0.0350223 |
| COPA | coatomer protein complex, subunit alpha | -0.0350077 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0349381 |
| SBF2 | SET binding factor 2 | -0.0340648 |
| PGK1 | phosphoglycerate kinase 1 | -0.0337511 |
| TENM2 | teneurin transmembrane protein 2 | -0.0335504 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0335066 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0332786 |
| COL6A3 | collagen, type VI, alpha 3 | -0.033166 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0329125 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0320014 |
| RASA3 | RAS p21 protein activator 3 | -0.0313472 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0313087 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0306053 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.030518 |
| WDR45B | WD repeat domain 45B | -0.0302657 |
| HDLBP | high density lipoprotein binding protein | -0.0301923 |
| ADM | adrenomedullin | -0.0301706 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | -0.0299301 |
| RLF | rearranged L-myc fusion | -0.0298969 |
| SAR1A | secretion associated, Ras related GTPase 1A | -0.029586 |
| FLNB | filamin B, beta | -0.0294695 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | -0.0292325 |
| OGA | O-GlcNAcase | -0.0288436 |
| HPCAL1 | hippocalcin-like 1 | -0.0285808 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | -0.0283318 |
| CADM1 | cell adhesion molecule 1 | -0.0282052 |
| MORF4L2 | mortality factor 4 like 2 | -0.0277762 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.027625 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0274174 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0273477 |
| FMN1 | formin 1 | -0.0271691 |
| RPS19 | ribosomal protein S19 | -0.0271632 |
| SEC24D | SEC24 family member D | -0.0269474 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0267986 |
| FTL | ferritin, light polypeptide | -0.0267097 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0266926 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0266217 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0266124 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0264936 |
| IER3 | immediate early response 3 | -0.0262484 |
| FAM162A | family with sequence similarity 162, member A | -0.0262353 |
| NGLY1 | N-glycanase 1 | -0.0260547 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0258949 |
| THBS1 | thrombospondin 1 | -0.0257673 |
| TMEM263 | transmembrane protein 263 | -0.0257004 |
| TMEM165 | transmembrane protein 165 | -0.0253584 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0249852 |
| FSTL1 | follistatin-like 1 | -0.0248253 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0245193 |
| TFG | TRK-fused gene | -0.0243205 |
| QKI | QKI, KH domain containing, RNA binding | -0.0242058 |
| ATXN1 | ataxin 1 | -0.0240592 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0240119 |
| HOOK2 | hook microtubule-tethering protein 2 | -0.0239107 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0236269 |
| TNNC1 | troponin C type 1 (slow) | -0.023494 |
