| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Azithromycin (hydrate) perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Azithromycin (hydrate)_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.228546 |
| MT2A | metallothionein 2A | 0.178545 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.157122 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.137149 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.137066 |
| VEGFA | vascular endothelial growth factor A | 0.0992283 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0804355 |
| STC1 | stanniocalcin 1 | 0.0723443 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0706724 |
| VMP1 | vacuole membrane protein 1 | 0.0660374 |
| ASPH | aspartate beta-hydroxylase | 0.0596363 |
| RPS6 | ribosomal protein S6 | 0.0590782 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0564547 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.055822 |
| RPS2 | ribosomal protein S2 | 0.0542535 |
| RPS8 | ribosomal protein S8 | 0.053523 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0445972 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0443655 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0439974 |
| RPS12 | ribosomal protein S12 | 0.0425987 |
| MSN | moesin | 0.0420034 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0411949 |
| B2M | beta-2-microglobulin | 0.0409489 |
| ENO1 | enolase 1, (alpha) | 0.0408441 |
| ECE1 | endothelin converting enzyme 1 | 0.0396308 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0390445 |
| RND3 | Rho family GTPase 3 | 0.0371447 |
| CLU | clusterin | 0.0349189 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0349069 |
| CLMP | CXADR-like membrane protein | 0.0346292 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0337879 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0335079 |
| EFNA5 | ephrin-A5 | 0.0332292 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.032376 |
| RASA2 | RAS p21 protein activator 2 | 0.0322672 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0318065 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0316917 |
| FOSL1 | FOS-like antigen 1 | 0.0314161 |
| S100A9 | S100 calcium binding protein A9 | 0.0313384 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0302126 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0290931 |
| RPL11 | ribosomal protein L11 | 0.0287114 |
| ANXA5 | annexin A5 | 0.0282713 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0282524 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0282421 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.027895 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.0266348 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.026586 |
| RPL26 | ribosomal protein L26 | 0.0263404 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0257235 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0252514 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0250915 |
| HMGA2 | high mobility group AT-hook 2 | 0.0247378 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0246364 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0245741 |
| HAS2 | hyaluronan synthase 2 | 0.0245525 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0240543 |
| RPLP2 | ribosomal protein, large, P2 | 0.0238566 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0238493 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0236242 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0234865 |
| RPL21 | ribosomal protein L21 | 0.0234456 |
| HDAC9 | histone deacetylase 9 | 0.023404 |
| DSPP | dentin sialophosphoprotein | 0.0233016 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0231985 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.023116 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0230149 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0229714 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0228128 |
| MYO10 | myosin X | 0.0222284 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0221564 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.0219817 |
| BRD2 | bromodomain containing 2 | 0.0215647 |
| FBXL13 | F-box and leucine-rich repeat protein 13 | 0.0214434 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0212816 |
| RPS3 | ribosomal protein S3 | 0.0212581 |
| RPL23 | ribosomal protein L23 | 0.0210932 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0210734 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0207696 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0206983 |
| BPTF | bromodomain PHD finger transcription factor | 0.0206862 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0206809 |
| RPS19 | ribosomal protein S19 | 0.02054 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.0203188 |
| LAMB1 | laminin, beta 1 | 0.0202444 |
| TMF1 | TATA element modulatory factor 1 | 0.0201213 |
| IL6 | interleukin 6 | 0.0200149 |
| DUSP6 | dual specificity phosphatase 6 | 0.0198212 |
| S100A10 | S100 calcium binding protein A10 | 0.0198196 |
| PARD3 | par-3 family cell polarity regulator | 0.0197902 |
| RACK1 | receptor for activated C kinase 1 | 0.019576 |
| H1-4 | H1.4 linker histone, cluster member | 0.0195373 |
| RPL37A | ribosomal protein L37a | 0.0195238 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0194748 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0194176 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0193498 |
| ERBIN | erbb2 interacting protein | 0.0193422 |
| TMEM165 | transmembrane protein 165 | 0.0191676 |
| ITGB5 | integrin, beta 5 | 0.0191532 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0190134 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.332905 |
| COL6A3 | collagen, type VI, alpha 3 | -0.306067 |
| NDRG1 | N-myc downstream regulated 1 | -0.177632 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.135326 |
| COL1A1 | collagen, type I, alpha 1 | -0.130976 |
| CADM1 | cell adhesion molecule 1 | -0.102648 |
| COL1A2 | collagen, type I, alpha 2 | -0.0953524 |
| FBN1 | fibrillin 1 | -0.095116 |
| COL5A1 | collagen, type V, alpha 1 | -0.0855338 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0805842 |
| LOX | lysyl oxidase | -0.0762338 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.0727986 |
| TMSB10 | thymosin beta 10 | -0.0702803 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0674393 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0640361 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0627087 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0577556 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0564306 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0527216 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0485299 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0481879 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0474054 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0429113 |
| FLNA | filamin A, alpha | -0.0404654 |
| CD109 | CD109 molecule | -0.0404544 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0380579 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0377306 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0371435 |
| CALD1 | caldesmon 1 | -0.0368554 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0366232 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0364576 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0363736 |
| PDE10A | phosphodiesterase 10A | -0.0362114 |
| PLEC | plectin | -0.0356615 |
| TMSB4X | thymosin beta 4, X-linked | -0.0355054 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0353955 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0352394 |
| AHNAK | AHNAK nucleoprotein | -0.0338995 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0336318 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0331348 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0329296 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0328779 |
| VIM | vimentin | -0.0319831 |
| LDHA | lactate dehydrogenase A | -0.031822 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0316174 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0315212 |
| PALLD | palladin, cytoskeletal associated protein | -0.031456 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0309235 |
| SPAG9 | sperm associated antigen 9 | -0.0302204 |
| COL5A2 | collagen, type V, alpha 2 | -0.0301563 |
| FSTL1 | follistatin-like 1 | -0.0299358 |
| RPL35A | ribosomal protein L35a | -0.0298685 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0296585 |
| HOOK2 | hook microtubule-tethering protein 2 | -0.0296313 |
| HDLBP | high density lipoprotein binding protein | -0.0294259 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0291952 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0285494 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0284388 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0281961 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0280086 |
| STC2 | stanniocalcin 2 | -0.0272017 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0271257 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0268196 |
| LOXL2 | lysyl oxidase-like 2 | -0.0267916 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0264074 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0261981 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0258628 |
| PRR16 | proline rich 16 | -0.0257776 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0247378 |
| UBC | ubiquitin C | -0.0244617 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | -0.0243325 |
| POSTN | periostin, osteoblast specific factor | -0.0243095 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0242779 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0242776 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0241172 |
| TRAM2 | translocation associated membrane protein 2 | -0.0239767 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.0239527 |
| CCDC80 | coiled-coil domain containing 80 | -0.0236207 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0233971 |
| COPA | coatomer protein complex, subunit alpha | -0.0231672 |
| COL3A1 | collagen, type III, alpha 1 | -0.0230337 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0227886 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0226418 |
| CLINT1 | clathrin interactor 1 | -0.0222498 |
| EBF1 | early B-cell factor 1 | -0.0220806 |
| VCAN | versican | -0.0217686 |
| PRELID2 | PRELI domain containing 2 | -0.0215687 |
| ACTN4 | actinin, alpha 4 | -0.021343 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0211219 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0209934 |
| ADM | adrenomedullin | -0.0208758 |
| PIEZO2 | piezo-type mechanosensitive ion channel component 2 | -0.0207988 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0205989 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0205687 |
| EGR1 | early growth response 1 | -0.0205648 |
| MORF4L2 | mortality factor 4 like 2 | -0.0204788 |
| CAVIN1 | caveolae associated protein 1 | -0.0204411 |
| EHD2 | EH-domain containing 2 | -0.0203843 |
| CA12 | carbonic anhydrase XII | -0.0202167 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0201109 |
