| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Azithromycin (hydrate) perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Azithromycin (hydrate)_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | 0.126781 |
| RPS6 | ribosomal protein S6 | 0.0961881 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0853642 |
| RPS12 | ribosomal protein S12 | 0.0775337 |
| TMEM45B | transmembrane protein 45B | 0.0621843 |
| FAM13A | family with sequence similarity 13, member A | 0.0567826 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0557518 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.055614 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0546104 |
| ITPKC | inositol-trisphosphate 3-kinase C | 0.0493763 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.045865 |
| RNF24 | ring finger protein 24 | 0.0447801 |
| NDRG1 | N-myc downstream regulated 1 | 0.0444437 |
| TMC5 | transmembrane channel-like 5 | 0.0444232 |
| PLAUR | plasminogen activator, urokinase receptor | 0.044314 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0440135 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0437531 |
| RPS8 | ribosomal protein S8 | 0.0430571 |
| TXNIP | thioredoxin interacting protein | 0.0429458 |
| DNM2 | dynamin 2 | 0.0417818 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.041348 |
| RPS2 | ribosomal protein S2 | 0.0387901 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.038138 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0366319 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0362987 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0347758 |
| B2M | beta-2-microglobulin | 0.0346987 |
| ETV6 | ets variant 6 | 0.0327511 |
| BCL2L1 | BCL2-like 1 | 0.0320423 |
| BCAS1 | breast carcinoma amplified sequence 1 | 0.0315704 |
| CD2AP | CD2-associated protein | 0.0315315 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.0312847 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0306674 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | 0.0299779 |
| RPS3 | ribosomal protein S3 | 0.0283768 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | 0.0276643 |
| PGCKA1 | PDCD10 and GCKIII kinases associated 1 | 0.0275701 |
| PCED1B | PC-esterase domain containing 1B | 0.026875 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0264311 |
| BPTF | bromodomain PHD finger transcription factor | 0.0256809 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.025157 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0246836 |
| GOLM2 | golgi membrane protein 2 | 0.0246436 |
| CA12 | carbonic anhydrase XII | 0.0239279 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0236769 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0234273 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0233709 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0232698 |
| VEGFA | vascular endothelial growth factor A | 0.0232503 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0230707 |
| RPL34 | ribosomal protein L34 | 0.022905 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.0228425 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 0.0227292 |
| KRT19 | keratin 19, type I | 0.0225484 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0222747 |
| HKDC1 | hexokinase domain containing 1 | 0.0221162 |
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.0220377 |
| PHLPP2 | PH domain and leucine rich repeat protein phosphatase 2 | 0.0220276 |
| RPL21 | ribosomal protein L21 | 0.021916 |
| FRY | furry homolog (Drosophila) | 0.0218672 |
| MEIS2 | Meis homeobox 2 | 0.0218146 |
| CDK19 | cyclin-dependent kinase 19 | 0.0217842 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0217583 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0216161 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0214549 |
| DYNC2I1 | dynein 2 intermediate chain 1 | 0.0209974 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0208582 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0208274 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0207355 |
| SERF2 | small EDRK-rich factor 2 | 0.0204902 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0202908 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0198493 |
| LIPH | lipase, member H | 0.0193615 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.0193207 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.019157 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0190259 |
| USP54 | ubiquitin specific peptidase 54 | 0.0183257 |
| SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 | 0.0180807 |
| CLMN | calmin (calponin-like, transmembrane) | 0.0179851 |
| RPS7 | ribosomal protein S7 | 0.0179731 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0179358 |
| RPS13 | ribosomal protein S13 | 0.0178702 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0178633 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | 0.0178593 |
| RPS27 | ribosomal protein S27 | 0.017742 |
| TMF1 | TATA element modulatory factor 1 | 0.0177068 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.017677 |
| PAQR5 | progestin and adipoQ receptor family member V | 0.0176438 |
| KMT5B | lysine methyltransferase 5B | 0.0174311 |
| NECTIN2 | nectin cell adhesion molecule 2 | 0.0171823 |
| MPHOSPH8 | M-phase phosphoprotein 8 | 0.0171663 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | 0.0170486 |
| LCN2 | lipocalin 2 | 0.0168989 |
| KIAA0232 | KIAA0232 | 0.0167934 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0167814 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.016779 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0167318 |
| CLIC5 | chloride intracellular channel 5 | 0.0165257 |
| ADD3 | adducin 3 (gamma) | 0.0164855 |
| PLSCR1 | phospholipid scramblase 1 | 0.0162198 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | -0.181349 |
| KRT8 | keratin 8, type II | -0.110913 |
| ACTN4 | actinin, alpha 4 | -0.101975 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.101838 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0990375 |
| ANXA2 | annexin A2 | -0.0924438 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0804144 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.079466 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0714017 |
| UBC | ubiquitin C | -0.0707911 |
| INTS6 | integrator complex subunit 6 | -0.0695945 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0677953 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0668848 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0659921 |
| VCL | vinculin | -0.0651141 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0626034 |
| SQSTM1 | sequestosome 1 | -0.061523 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0614667 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0603836 |
| PTMA | prothymosin, alpha | -0.0602368 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0599844 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0581076 |
| LYZ | lysozyme | -0.0568584 |
| TMSB10 | thymosin beta 10 | -0.0556244 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0546143 |
| TJP1 | tight junction protein 1 | -0.0542779 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0535081 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0516451 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0508722 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.050775 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.049822 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.04798 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0479053 |
| POTEF | POTE ankyrin domain family, member F | -0.0474967 |
| FAT1 | FAT atypical cadherin 1 | -0.0471806 |
| TOP1 | topoisomerase (DNA) I | -0.0470057 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.046983 |
| RAB7A | RAB7A, member RAS oncogene family | -0.046891 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0463405 |
| LDHA | lactate dehydrogenase A | -0.0460323 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0458182 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.045706 |
| HMGA1 | high mobility group AT-hook 1 | -0.0454418 |
| EZR | ezrin | -0.0454319 |
| YBX1 | Y box binding protein 1 | -0.0453586 |
| HYOU1 | hypoxia up-regulated 1 | -0.0445495 |
| TUFT1 | tuftelin 1 | -0.0444072 |
| TES | testin LIM domain protein | -0.0435804 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0426813 |
| CANX | calnexin | -0.0425947 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0419791 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.041696 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0409874 |
| PKM | pyruvate kinase, muscle | -0.0407968 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0407451 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0399914 |
| FAM91A1 | family with sequence similarity 91, member A1 | -0.0399875 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0396358 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0396149 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0393738 |
| ATXN1 | ataxin 1 | -0.0392984 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0387483 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | -0.0379028 |
| KRT18 | keratin 18, type I | -0.0376517 |
| AHNAK | AHNAK nucleoprotein | -0.0374318 |
| ACTG1 | actin gamma 1 | -0.0368104 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0367608 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | -0.0365073 |
| SDCBP | syndecan binding protein (syntenin) | -0.0356886 |
| ECT2 | epithelial cell transforming 2 | -0.0350907 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0349529 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0345469 |
| MORF4L2 | mortality factor 4 like 2 | -0.034452 |
| RTN4 | reticulon 4 | -0.0342332 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0341694 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0340493 |
| SETX | senataxin | -0.0339779 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0339429 |
| IPO7 | importin 7 | -0.0338341 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0333129 |
| PCBP2 | poly(rC) binding protein 2 | -0.0332181 |
| PLEC | plectin | -0.0329942 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0328666 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0326595 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | -0.0325432 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0325128 |
| PTK2 | protein tyrosine kinase 2 | -0.0324125 |
| ATAD2 | ATPase family, AAA domain containing 2 | -0.0323573 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.0316417 |
| EGR1 | early growth response 1 | -0.031627 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0313588 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0312679 |
| ARF4 | ADP-ribosylation factor 4 | -0.0311984 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0311423 |
| PDZD8 | PDZ domain containing 8 | -0.0311397 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0311385 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0309074 |
| TMEM65 | transmembrane protein 65 | -0.0308177 |
| C6ORF62 | chromosome 6 open reading frame 62 | -0.0304666 |
| DST | dystonin | -0.0303537 |
