| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Azithromycin (hydrate) perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Azithromycin (hydrate)_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.10841 |
| LMO7 | LIM domain 7 | 0.105808 |
| MTSS1 | metastasis suppressor 1 | 0.0992298 |
| MSN | moesin | 0.0982908 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0929169 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0850489 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0825937 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0669321 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0615326 |
| MEF2A | myocyte enhancer factor 2A | 0.0601302 |
| UBC | ubiquitin C | 0.0556396 |
| CD44 | CD44 molecule (Indian blood group) | 0.054081 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0533871 |
| TXNIP | thioredoxin interacting protein | 0.0531036 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0526564 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0525285 |
| PLS3 | plastin 3 | 0.0517431 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0495091 |
| IFI44L | interferon-induced protein 44-like | 0.0493964 |
| HMGA2 | high mobility group AT-hook 2 | 0.0482759 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0480453 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0474202 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0473018 |
| DOK5 | docking protein 5 | 0.0467371 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0460199 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.0459764 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0456771 |
| VMP1 | vacuole membrane protein 1 | 0.0445428 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0442569 |
| RIGI | RNA sensor RIG-I | 0.0424967 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0421737 |
| DIAPH1 | diaphanous-related formin 1 | 0.0421098 |
| TPM3 | tropomyosin 3 | 0.0409627 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0407443 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0398445 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | 0.0395642 |
| DST | dystonin | 0.0378865 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0372688 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0371765 |
| SMAD3 | SMAD family member 3 | 0.0361945 |
| AOPEP | aminopeptidase O (putative) | 0.0356918 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.035 |
| LAMC2 | laminin, gamma 2 | 0.0345531 |
| RPL21 | ribosomal protein L21 | 0.0344234 |
| PCDH1 | protocadherin 1 | 0.0343382 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0340207 |
| ECE1 | endothelin converting enzyme 1 | 0.0339286 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0338541 |
| EFNA5 | ephrin-A5 | 0.0336697 |
| SEPTIN9 | septin 9 | 0.0335424 |
| SIK3 | SIK family kinase 3 | 0.0334956 |
| BARX2 | BARX homeobox 2 | 0.0334446 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0333059 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0328541 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.032659 |
| RPS12 | ribosomal protein S12 | 0.0322684 |
| STC1 | stanniocalcin 1 | 0.0322398 |
| SH3PXD2A | SH3 and PX domains 2A | 0.0319817 |
| RNF217 | ring finger protein 217 | 0.0319076 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0317383 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | 0.0314263 |
| MYOF | myoferlin | 0.031275 |
| SET | SET nuclear proto-oncogene | 0.031158 |
| RPS2 | ribosomal protein S2 | 0.0310782 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0310318 |
| FRMD6 | FERM domain containing 6 | 0.0299408 |
| RASAL2 | RAS protein activator like 2 | 0.0292261 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0288729 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0287655 |
| ENO1 | enolase 1, (alpha) | 0.0281562 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0281251 |
| POTEF | POTE ankyrin domain family, member F | 0.0280235 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0280038 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0278314 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0276259 |
| LUZP1 | leucine zipper protein 1 | 0.0272908 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0272579 |
| ASPH | aspartate beta-hydroxylase | 0.0268922 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 | 0.0267215 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0265598 |
| SVIL | supervillin | 0.0262843 |
| VCL | vinculin | 0.0261015 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0260403 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0257306 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0256563 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0255675 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0255583 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0253599 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0253188 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0253131 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0249271 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0248785 |
| SLK | STE20-like kinase | 0.0248674 |
| MT1E | metallothionein 1E | 0.0246957 |
| NCOR2 | nuclear receptor corepressor 2 | 0.024622 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0246123 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0245018 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.024422 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0243528 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0239113 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FLNB | filamin B, beta | -0.172782 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.141791 |
| TMSB10 | thymosin beta 10 | -0.12701 |
| NDRG1 | N-myc downstream regulated 1 | -0.117275 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.108189 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0935856 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0910418 |
| TMSB4X | thymosin beta 4, X-linked | -0.0808993 |
| IGF2 | insulin-like growth factor 2 | -0.0805189 |
| PTMA | prothymosin, alpha | -0.0804214 |
| SULF1 | sulfatase 1 | -0.0784523 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0775575 |
| EMP1 | epithelial membrane protein 1 | -0.0738607 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0736251 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | -0.064745 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0644524 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0634319 |
| GNAS | GNAS complex locus | -0.0599549 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0595275 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0584323 |
| S100A10 | S100 calcium binding protein A10 | -0.058392 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0562101 |
| LMNA | lamin A/C | -0.055025 |
| KRT17 | keratin 17, type I | -0.0547282 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0525037 |
| MORF4L2 | mortality factor 4 like 2 | -0.051748 |
| RPLP1 | ribosomal protein, large, P1 | -0.0503366 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0476547 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0472926 |
| RBM39 | RNA binding motif protein 39 | -0.0470836 |
| CANX | calnexin | -0.0460524 |
| HM13 | histocompatibility (minor) 13 | -0.0459766 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0456374 |
| RPL35A | ribosomal protein L35a | -0.0444383 |
| HLA-B | major histocompatibility complex, class I, B | -0.0440808 |
| AHNAK | AHNAK nucleoprotein | -0.0434272 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0432355 |
| EFHD2 | EF-hand domain family, member D2 | -0.043142 |
| RPS21 | ribosomal protein S21 | -0.0430534 |
| ANXA2 | annexin A2 | -0.0428348 |
| FSCN1 | fascin actin-bundling protein 1 | -0.0426704 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0421002 |
| CAVIN1 | caveolae associated protein 1 | -0.0418307 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0417135 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0415772 |
| HDLBP | high density lipoprotein binding protein | -0.0408298 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0400836 |
| PGK1 | phosphoglycerate kinase 1 | -0.0392195 |
| PODXL | podocalyxin-like | -0.0392127 |
| S100A2 | S100 calcium binding protein A2 | -0.0390769 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.0390542 |
| SQLE | squalene epoxidase | -0.0378492 |
| KRT6A | keratin 6A, type II | -0.0373087 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0372534 |
| ARF1 | ADP-ribosylation factor 1 | -0.0364765 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0363106 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0363019 |
| CUL4B | cullin 4B | -0.0361926 |
| MT2A | metallothionein 2A | -0.0360768 |
| WASF2 | WAS protein family, member 2 | -0.0360194 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0354389 |
| H1-0 | H1.0 linker histone | -0.0347923 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0347554 |
| S100A4 | S100 calcium binding protein A4 | -0.0343783 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | -0.0342323 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0342027 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0341216 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0335704 |
| GOLGA2 | golgin A2 | -0.0332346 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0331303 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0327336 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0326028 |
| TMEM263 | transmembrane protein 263 | -0.0320836 |
| ITSN1 | intersectin 1 (SH3 domain protein) | -0.0319211 |
| EZR | ezrin | -0.0308874 |
| ANKRD33B | ankyrin repeat domain 33B | -0.0307765 |
| CALR | calreticulin | -0.0304704 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0303672 |
| ANLN | anillin, actin binding protein | -0.030268 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.030225 |
| BLCAP | bladder cancer associated protein | -0.0302025 |
| RPL32 | ribosomal protein L32 | -0.0294338 |
| RPL34 | ribosomal protein L34 | -0.0288015 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0283979 |
| FSTL1 | follistatin-like 1 | -0.0282038 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0279043 |
| PLAC8 | placenta-specific 8 | -0.0277595 |
| CD99 | CD99 molecule | -0.0276233 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0275026 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0274262 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0274038 |
| RPL11 | ribosomal protein L11 | -0.0269426 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.026667 |
| SAR1A | secretion associated, Ras related GTPase 1A | -0.0265102 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0265021 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0263788 |
| CLINT1 | clathrin interactor 1 | -0.0263471 |
| OGA | O-GlcNAcase | -0.0263077 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0260298 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0259373 |
