| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Azithromycin (hydrate) perturbation in J82 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Azithromycin (hydrate)_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.255376 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.231481 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.150287 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.103542 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0840568 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0819845 |
| ERBIN | erbb2 interacting protein | 0.0752094 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0664992 |
| VMP1 | vacuole membrane protein 1 | 0.0597386 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0590999 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0582588 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0580178 |
| INTS6 | integrator complex subunit 6 | 0.0566062 |
| MSN | moesin | 0.0541662 |
| CD44 | CD44 molecule (Indian blood group) | 0.0526296 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0473398 |
| DST | dystonin | 0.0472158 |
| RND3 | Rho family GTPase 3 | 0.0464923 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0447587 |
| ASPH | aspartate beta-hydroxylase | 0.0438007 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0436099 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0427114 |
| RPS6 | ribosomal protein S6 | 0.0418267 |
| RPL21 | ribosomal protein L21 | 0.0414831 |
| GOLGB1 | golgin B1 | 0.0409523 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0407917 |
| RPS2 | ribosomal protein S2 | 0.0398705 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0391483 |
| RPS12 | ribosomal protein S12 | 0.038288 |
| VCL | vinculin | 0.0381906 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0378963 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0365565 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0347303 |
| NAV2 | neuron navigator 2 | 0.0340582 |
| H1-4 | H1.4 linker histone, cluster member | 0.033819 |
| CENPF | centromere protein F, 350/400kDa | 0.0336263 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0326305 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0324434 |
| SMAD3 | SMAD family member 3 | 0.0313433 |
| EFNA5 | ephrin-A5 | 0.0308755 |
| ZNF841 | zinc finger protein 841 | 0.0305601 |
| BPTF | bromodomain PHD finger transcription factor | 0.0293619 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0293327 |
| H1-2 | H1.2 linker histone, cluster member | 0.0291703 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0291613 |
| MKI67 | marker of proliferation Ki-67 | 0.0290677 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0290585 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0281983 |
| RPS3 | ribosomal protein S3 | 0.0278724 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.027694 |
| TLE4 | transducin-like enhancer of split 4 | 0.0271129 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0270027 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0269103 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0259948 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0259415 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0255485 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.025488 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0253757 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0250149 |
| RPS8 | ribosomal protein S8 | 0.0247905 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0246609 |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.0244916 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.024202 |
| MCL1 | myeloid cell leukemia 1 | 0.0239168 |
| NABP1 | nucleic acid binding protein 1 | 0.0236639 |
| ATXN1 | ataxin 1 | 0.0236213 |
| MYO10 | myosin X | 0.0232272 |
| TPM3 | tropomyosin 3 | 0.0230351 |
| VEGFA | vascular endothelial growth factor A | 0.0226824 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0222931 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.022263 |
| PRELID2 | PRELI domain containing 2 | 0.0221977 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0220946 |
| TOP1 | topoisomerase (DNA) I | 0.0220457 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.0216222 |
| IL6ST | interleukin 6 signal transducer | 0.0215934 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0215392 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0214913 |
| RAD51B | RAD51 paralog B | 0.0214904 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0211323 |
| PLSCR1 | phospholipid scramblase 1 | 0.0210334 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0210305 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0207415 |
| ANGPTL4 | angiopoietin-like 4 | 0.0202554 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0199824 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0194471 |
| GPHN | gephyrin | 0.0192447 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.019223 |
| SON | SON DNA binding protein | 0.019192 |
| RPL11 | ribosomal protein L11 | 0.0191716 |
| FHIT | fragile histidine triad | 0.0190644 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0190487 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0187989 |
| SUPT16H | suppressor of Ty 16 homolog (S. cerevisiae) | 0.0186939 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0185792 |
| CALD1 | caldesmon 1 | 0.0185393 |
| RASA2 | RAS p21 protein activator 2 | 0.0185233 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0185184 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0182894 |
| RPL26 | ribosomal protein L26 | 0.0181908 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.243746 |
| FN1 | fibronectin 1 | -0.22463 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.160361 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.15693 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.155316 |
| HLA-B | major histocompatibility complex, class I, B | -0.129531 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.122693 |
| FTL | ferritin, light polypeptide | -0.118155 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.113872 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0984768 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0967821 |
| PTMA | prothymosin, alpha | -0.0758098 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0744858 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0688601 |
| PKM | pyruvate kinase, muscle | -0.0655959 |
| CCBE1 | collagen and calcium binding EGF domains 1 | -0.0626924 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0625337 |
| GLIS3 | GLIS family zinc finger 3 | -0.0622394 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0592867 |
| TMSB10 | thymosin beta 10 | -0.0592614 |
| SLC12A8 | solute carrier family 12, member 8 | -0.0589148 |
| TMSB4X | thymosin beta 4, X-linked | -0.0588107 |
| POSTN | periostin, osteoblast specific factor | -0.0577191 |
| PLCB4 | phospholipase C, beta 4 | -0.0572836 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.0569715 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0556741 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0552486 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.05459 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0541374 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0539947 |
| RPL35A | ribosomal protein L35a | -0.0523099 |
| CALR | calreticulin | -0.0480779 |
| SULF1 | sulfatase 1 | -0.0477696 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0458675 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0448026 |
| POTEF | POTE ankyrin domain family, member F | -0.0433323 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | -0.0424249 |
| S100A6 | S100 calcium binding protein A6 | -0.0421151 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0418018 |
| CTSD | cathepsin D | -0.0412881 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0401356 |
| HLA-A | major histocompatibility complex, class I, A | -0.0396991 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0384987 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0374609 |
| PPME1 | protein phosphatase methylesterase 1 | -0.0365678 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0363076 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0361551 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0360814 |
| ARF4 | ADP-ribosylation factor 4 | -0.0357294 |
| TMEM178B | transmembrane protein 178B | -0.0356504 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0355415 |
| HLA-C | major histocompatibility complex, class I, C | -0.0355091 |
| VIM | vimentin | -0.0351914 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0347434 |
| TUBB | tubulin, beta class I | -0.0344923 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.034432 |
| COL5A1 | collagen, type V, alpha 1 | -0.0342254 |
| TPM1 | tropomyosin 1 (alpha) | -0.0340254 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0338386 |
| NUP58 | nucleoporin 58 | -0.0333037 |
| PFN1 | profilin 1 | -0.0327441 |
| TXNRD1 | thioredoxin reductase 1 | -0.0325461 |
| FSTL1 | follistatin-like 1 | -0.0323662 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0318329 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0316025 |
| PLIN2 | perilipin 2 | -0.0313102 |
| TPD52 | tumor protein D52 | -0.0312006 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.031024 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0308069 |
| HLA-E | major histocompatibility complex, class I, E | -0.0307869 |
| ATP13A3 | ATPase type 13A3 | -0.0302972 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0302029 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0299761 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.029953 |
| CUL4B | cullin 4B | -0.029431 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0288216 |
| CCDC80 | coiled-coil domain containing 80 | -0.0287075 |
| USP3 | ubiquitin specific peptidase 3 | -0.0279792 |
| RLF | rearranged L-myc fusion | -0.0279388 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0273199 |
| PGK1 | phosphoglycerate kinase 1 | -0.0267471 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0265714 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0262798 |
| MAP1B | microtubule-associated protein 1B | -0.0260252 |
| CBX3 | chromobox homolog 3 | -0.0259037 |
| COL5A2 | collagen, type V, alpha 2 | -0.0256656 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0256217 |
| PDE10A | phosphodiesterase 10A | -0.0254674 |
| JUN | jun proto-oncogene | -0.0254169 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0252172 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0250765 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.024983 |
| TRAM1 | translocation associated membrane protein 1 | -0.0249411 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0248696 |
| TKT | transketolase | -0.0242654 |
| MAP4 | microtubule-associated protein 4 | -0.0238615 |
| SBF2 | SET binding factor 2 | -0.0237247 |
| FAR1 | fatty acyl CoA reductase 1 | -0.0235818 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0232087 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0231316 |
