| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Azithromycin (hydrate) perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Azithromycin (hydrate)_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AREG | amphiregulin | 0.106231 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.105396 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0887333 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0782568 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0777502 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0717432 |
| LMO7 | LIM domain 7 | 0.0708807 |
| MYO1E | myosin IE | 0.0615189 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0574006 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0570295 |
| RPS12 | ribosomal protein S12 | 0.0567683 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0554508 |
| DSPP | dentin sialophosphoprotein | 0.0549979 |
| VMP1 | vacuole membrane protein 1 | 0.0528855 |
| MUC13 | mucin 13, cell surface associated | 0.0516071 |
| RPS2 | ribosomal protein S2 | 0.0496611 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0456972 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0451397 |
| LAMA4 | laminin, alpha 4 | 0.0434222 |
| TXNIP | thioredoxin interacting protein | 0.0420082 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0402733 |
| ASPH | aspartate beta-hydroxylase | 0.0394868 |
| EREG | epiregulin | 0.0369758 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0360363 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0350015 |
| MED13 | mediator complex subunit 13 | 0.0345648 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0336033 |
| USP53 | ubiquitin specific peptidase 53 | 0.0329843 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0326211 |
| ONECUT3 | one cut homeobox 3 | 0.0324588 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0323048 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0322596 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0320345 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0311276 |
| H1-4 | H1.4 linker histone, cluster member | 0.0298032 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0294835 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0269122 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0268543 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0259113 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0253671 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0252626 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0251275 |
| ACTG1 | actin gamma 1 | 0.0249944 |
| H1-0 | H1.0 linker histone | 0.0247624 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0242325 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.023631 |
| LURAP1L | leucine rich adaptor protein 1-like | 0.0233406 |
| VCL | vinculin | 0.022967 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0226802 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0225064 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0223313 |
| MT2A | metallothionein 2A | 0.021917 |
| RPS7 | ribosomal protein S7 | 0.02188 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0218631 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0213 |
| KLF6 | Kruppel-like factor 6 | 0.0212357 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0212077 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0210469 |
| EFNB2 | ephrin-B2 | 0.0209875 |
| CENPF | centromere protein F, 350/400kDa | 0.0208385 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.020753 |
| IER3 | immediate early response 3 | 0.0205902 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0205034 |
| RPL26 | ribosomal protein L26 | 0.0204709 |
| SQSTM1 | sequestosome 1 | 0.020458 |
| RPS3 | ribosomal protein S3 | 0.0202244 |
| RPL21 | ribosomal protein L21 | 0.0200907 |
| ENO1 | enolase 1, (alpha) | 0.0199098 |
| LIPH | lipase, member H | 0.0196865 |
| POF1B | premature ovarian failure, 1B | 0.0194935 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | 0.0194173 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.019367 |
| TMEM45B | transmembrane protein 45B | 0.0192794 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0192006 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0190155 |
| DUSP16 | dual specificity phosphatase 16 | 0.018973 |
| GOLGB1 | golgin B1 | 0.0186851 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | 0.0185817 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0185055 |
| CD2AP | CD2-associated protein | 0.0184313 |
| LAMC2 | laminin, gamma 2 | 0.018282 |
| H1-2 | H1.2 linker histone, cluster member | 0.0182686 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0178049 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | 0.0177629 |
| CSTB | cystatin B (stefin B) | 0.0176671 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0176329 |
| LDHA | lactate dehydrogenase A | 0.017373 |
| IGFL2 | IGF-like family member 2 | 0.0173479 |
| ZNF503 | zinc finger protein 503 | 0.0171395 |
| PDZD8 | PDZ domain containing 8 | 0.0169012 |
| DSG2 | desmoglein 2 | 0.0167012 |
| EMP1 | epithelial membrane protein 1 | 0.0165984 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0163744 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0162646 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0161716 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.0160906 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0160897 |
| CD44 | CD44 molecule (Indian blood group) | 0.0160412 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0159892 |
| CAB39 | calcium binding protein 39 | 0.0157489 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.227697 |
| TMSB10 | thymosin beta 10 | -0.205814 |
| NPSR1 | neuropeptide S receptor 1 | -0.203589 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.15665 |
| PTMA | prothymosin, alpha | -0.152749 |
| GPHN | gephyrin | -0.11284 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0924394 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0892683 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0840319 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0830694 |
| TNS4 | tensin 4 | -0.0815046 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0805085 |
| FLNB | filamin B, beta | -0.0664566 |
| PIGR | polymeric immunoglobulin receptor | -0.0599536 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0596322 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0574924 |
| ANXA2 | annexin A2 | -0.057145 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0568111 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | -0.0558273 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0552486 |
| RPL35A | ribosomal protein L35a | -0.0541875 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0531945 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0520378 |
| RPLP1 | ribosomal protein, large, P1 | -0.0512491 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0493011 |
| CALB1 | calbindin 1, 28kDa | -0.0484032 |
| MSI2 | musashi RNA-binding protein 2 | -0.0468422 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0460627 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0458769 |
| ITGB4 | integrin, beta 4 | -0.0457451 |
| ACTN4 | actinin, alpha 4 | -0.0451545 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0434853 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0434719 |
| TFF3 | trefoil factor 3 (intestinal) | -0.0420425 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.040883 |
| PKM | pyruvate kinase, muscle | -0.0398882 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0398573 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0392765 |
| PTEN | phosphatase and tensin homolog | -0.0389049 |
| SAMD5 | sterile alpha motif domain containing 5 | -0.0384298 |
| KRT8 | keratin 8, type II | -0.0382741 |
| MED13L | mediator complex subunit 13-like | -0.0381662 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0380782 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0378326 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0377786 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0375032 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | -0.0374994 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0372789 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.0366834 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.0351893 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.035123 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | -0.0349304 |
| AHNAK | AHNAK nucleoprotein | -0.0349285 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.034776 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0344833 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0343515 |
| MECOM | MDS1 and EVI1 complex locus | -0.0343422 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0339975 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0338451 |
| NRXN3 | neurexin 3 | -0.0337815 |
| PARD3 | par-3 family cell polarity regulator | -0.0337524 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0337461 |
| RPS19 | ribosomal protein S19 | -0.0337432 |
| POTEF | POTE ankyrin domain family, member F | -0.0336902 |
| COG5 | component of oligomeric golgi complex 5 | -0.0329591 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0329451 |
| RREB1 | ras responsive element binding protein 1 | -0.0321562 |
| S100A6 | S100 calcium binding protein A6 | -0.0321171 |
| PTK2 | protein tyrosine kinase 2 | -0.0320637 |
| FHIT | fragile histidine triad | -0.0318728 |
| HMGA1 | high mobility group AT-hook 1 | -0.0314874 |
| RNF43 | ring finger protein 43 | -0.0314251 |
| ITGA6 | integrin, alpha 6 | -0.0312451 |
| CCNY | cyclin Y | -0.0311164 |
| MUC17 | mucin 17, cell surface associated | -0.0309397 |
| SBF2 | SET binding factor 2 | -0.0307412 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0306316 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0299668 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0298187 |
| RNF217 | ring finger protein 217 | -0.029817 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0284888 |
| ABHD2 | abhydrolase domain containing 2 | -0.0281039 |
| USP3 | ubiquitin specific peptidase 3 | -0.0280205 |
| AGR2 | anterior gradient 2 | -0.0278329 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0277916 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0277516 |
| EPHB2 | EPH receptor B2 | -0.0275669 |
| LSAMP | limbic system-associated membrane protein | -0.027547 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0271936 |
| CALR | calreticulin | -0.0269924 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0269265 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0267608 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0267555 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0262894 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0260702 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0259967 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0259704 |
| INSIG1 | insulin induced gene 1 | -0.0259489 |
| FOXO1 | forkhead box O1 | -0.0258161 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0257415 |
