| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Azithromycin (hydrate) perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Azithromycin (hydrate)_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.12428 |
| SLTM | SAFB-like, transcription modulator | 0.0895327 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0728484 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.0678673 |
| HOMER1 | homer scaffolding protein 1 | 0.0653347 |
| STC1 | stanniocalcin 1 | 0.0628899 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0625647 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0607196 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.060095 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.059037 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.057806 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | 0.0574345 |
| INTS6 | integrator complex subunit 6 | 0.0565363 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0539932 |
| GRAMD1B | GRAM domain containing 1B | 0.0531373 |
| VMP1 | vacuole membrane protein 1 | 0.0524323 |
| AREG | amphiregulin | 0.0517736 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.051537 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0488888 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0486595 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.04824 |
| KYNU | kynureninase | 0.0458466 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0444649 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0422457 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0422406 |
| MAP7 | microtubule-associated protein 7 | 0.0417167 |
| SIK3 | SIK family kinase 3 | 0.0409389 |
| BMP6 | bone morphogenetic protein 6 | 0.03846 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.037334 |
| TOP1 | topoisomerase (DNA) I | 0.0361626 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0353154 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0330083 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0317248 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0315537 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0311697 |
| CES1 | carboxylesterase 1 | 0.0305773 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0305015 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0301188 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0288901 |
| RPS2 | ribosomal protein S2 | 0.0288123 |
| MKI67 | marker of proliferation Ki-67 | 0.0287329 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.0284418 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0274546 |
| BPTF | bromodomain PHD finger transcription factor | 0.0273297 |
| SPAG9 | sperm associated antigen 9 | 0.0272567 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0272004 |
| SON | SON DNA binding protein | 0.0271742 |
| RAD51B | RAD51 paralog B | 0.0265476 |
| JMJD1C | jumonji domain containing 1C | 0.0263815 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0261721 |
| WWOX | WW domain containing oxidoreductase | 0.0258511 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0258493 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.025568 |
| SYAP1 | synapse associated protein 1 | 0.0251645 |
| CPE | carboxypeptidase E | 0.0250603 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0244153 |
| MT2A | metallothionein 2A | 0.0242154 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0240308 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0240048 |
| RPS6 | ribosomal protein S6 | 0.0238875 |
| VEGFC | vascular endothelial growth factor C | 0.023791 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0237049 |
| UBR1 | ubiquitin protein ligase E3 component n-recognin 1 | 0.0234008 |
| ATF6 | activating transcription factor 6 | 0.0231274 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0229627 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0227422 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0227225 |
| GPHN | gephyrin | 0.0224483 |
| MCL1 | myeloid cell leukemia 1 | 0.0222243 |
| OXSR1 | oxidative stress responsive 1 | 0.021975 |
| PNN | pinin, desmosome associated protein | 0.0219594 |
| NTSR1 | neurotensin receptor 1 (high affinity) | 0.0218539 |
| HMGA2 | high mobility group AT-hook 2 | 0.0217133 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0216729 |
| SMYD3 | SET and MYND domain containing 3 | 0.0212171 |
| DTNA | dystrobrevin, alpha | 0.0210209 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0209701 |
| TASOR2 | transcription activation suppressor family member 2 | 0.0209434 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0208758 |
| BRD2 | bromodomain containing 2 | 0.0208168 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0207404 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.0206659 |
| IRS2 | insulin receptor substrate 2 | 0.02062 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0205751 |
| PPP4R2 | protein phosphatase 4, regulatory subunit 2 | 0.0205509 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0204256 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0202899 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0202484 |
| AGO3 | argonaute RISC catalytic component 3 | 0.0202395 |
| NRDC | nardilysin convertase | 0.0201138 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0200924 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0199157 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0198752 |
| EXOC6B | exocyst complex component 6B | 0.0197718 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0197165 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0197143 |
| YBX3 | Y box binding protein 3 | 0.0195912 |
| ZC3H12B | zinc finger CCCH-type containing 12B | 0.0195277 |
| LRP12 | low density lipoprotein receptor-related protein 12 | 0.0195132 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0194714 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.245382 |
| TMSB10 | thymosin beta 10 | -0.169927 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.166553 |
| EGFR | epidermal growth factor receptor | -0.141488 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.13995 |
| ASPH | aspartate beta-hydroxylase | -0.138538 |
| UBC | ubiquitin C | -0.112164 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.110594 |
| LAMC2 | laminin, gamma 2 | -0.101933 |
| ANXA2 | annexin A2 | -0.0850388 |
| AHNAK | AHNAK nucleoprotein | -0.0841493 |
| LDHA | lactate dehydrogenase A | -0.0824336 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0817832 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.076526 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0709735 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0689865 |
| ENO1 | enolase 1, (alpha) | -0.0682982 |
| TXNRD1 | thioredoxin reductase 1 | -0.0673951 |
| PKM | pyruvate kinase, muscle | -0.0666072 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0618522 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0586121 |
| NDRG1 | N-myc downstream regulated 1 | -0.0581251 |
| PGK1 | phosphoglycerate kinase 1 | -0.0568358 |
| HDLBP | high density lipoprotein binding protein | -0.0541279 |
| KRT8 | keratin 8, type II | -0.0531806 |
| KRT18 | keratin 18, type I | -0.052815 |
| LMO7 | LIM domain 7 | -0.0520748 |
| H1-0 | H1.0 linker histone | -0.051037 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.050241 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0498119 |
| RPS27A | ribosomal protein S27a | -0.0484225 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0456822 |
| FAM13A | family with sequence similarity 13, member A | -0.0456386 |
| TMEM165 | transmembrane protein 165 | -0.0449295 |
| ACTG1 | actin gamma 1 | -0.0440719 |
| PTMA | prothymosin, alpha | -0.0425638 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.042543 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0409322 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0407101 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0401796 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0394894 |
| S100A10 | S100 calcium binding protein A10 | -0.0394098 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0389101 |
| FLNB | filamin B, beta | -0.0384436 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0382795 |
| RPL35A | ribosomal protein L35a | -0.0350719 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0350051 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0349221 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.034837 |
| PLEC | plectin | -0.0344639 |
| KRT7 | keratin 7, type II | -0.0336944 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0330483 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0330432 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.0329932 |
| S100A6 | S100 calcium binding protein A6 | -0.0329107 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0328779 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0325548 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0323391 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0320405 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0304284 |
| OGA | O-GlcNAcase | -0.0303272 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0302218 |
| TNS3 | tensin 3 | -0.0295411 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.029537 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.02947 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0289049 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0288689 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0288167 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0283462 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0281212 |
| RPS24 | ribosomal protein S24 | -0.0277014 |
| SCEL | sciellin | -0.0275349 |
| MYOF | myoferlin | -0.0271966 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0270976 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0269206 |
| TPD52 | tumor protein D52 | -0.026864 |
| WDR45B | WD repeat domain 45B | -0.0260363 |
| SDC4 | syndecan 4 | -0.0258864 |
| AMOTL1 | angiomotin like 1 | -0.0249467 |
| CELSR1 | cadherin, EGF LAG seven-pass G-type receptor 1 | -0.0247996 |
| MGAT4C | MGAT4 family, member C | -0.0247849 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0246641 |
| ARRDC3 | arrestin domain containing 3 | -0.024443 |
| TPM4 | tropomyosin 4 | -0.0244417 |
| FLNA | filamin A, alpha | -0.0243376 |
| LAMB3 | laminin, beta 3 | -0.0241179 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0240089 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0239791 |
| PPP2R2C | protein phosphatase 2, regulatory subunit B, gamma | -0.0237979 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.023767 |
| HOOK2 | hook microtubule-tethering protein 2 | -0.0237412 |
| FRYL | FRY-like | -0.0235576 |
| FTL | ferritin, light polypeptide | -0.0235308 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0234708 |
| CALR | calreticulin | -0.022953 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0227487 |
| GM2A | GM2 ganglioside activator | -0.0223918 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0223399 |
| PDE8A | phosphodiesterase 8A | -0.0223347 |
| AGR2 | anterior gradient 2 | -0.0222937 |
