| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Azithromycin (hydrate) perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Azithromycin (hydrate)_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.305992 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.136511 |
| GLCCI1 | glucocorticoid induced 1 | 0.078661 |
| RAI14 | retinoic acid induced 14 | 0.0752785 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0686307 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0610627 |
| NTN4 | netrin 4 | 0.0608946 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0538839 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0533828 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0513157 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0508704 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0500526 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0482021 |
| SMAD3 | SMAD family member 3 | 0.0481054 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0473942 |
| FN1 | fibronectin 1 | 0.0458196 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0437503 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0417637 |
| ZNF638 | zinc finger protein 638 | 0.0408941 |
| HMGA2 | high mobility group AT-hook 2 | 0.0405242 |
| IFI44L | interferon-induced protein 44-like | 0.0395428 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0392578 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0390954 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0390588 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0369754 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0353173 |
| VMP1 | vacuole membrane protein 1 | 0.0351233 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0350464 |
| ADD3 | adducin 3 (gamma) | 0.0332369 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0331177 |
| STK38L | serine/threonine kinase 38 like | 0.0328706 |
| SQSTM1 | sequestosome 1 | 0.0312901 |
| ENO1 | enolase 1, (alpha) | 0.0310386 |
| OPTN | optineurin | 0.0299805 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0298378 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0295974 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0290508 |
| ASPH | aspartate beta-hydroxylase | 0.0289799 |
| NRP1 | neuropilin 1 | 0.028774 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0284279 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0281719 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0277681 |
| VEGFA | vascular endothelial growth factor A | 0.0273787 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0271584 |
| ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif, 14 | 0.0270897 |
| NAV2 | neuron navigator 2 | 0.0267999 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0267924 |
| SKIL | SKI-like proto-oncogene | 0.0260691 |
| SYT1 | synaptotagmin I | 0.0258185 |
| RND3 | Rho family GTPase 3 | 0.025548 |
| DST | dystonin | 0.0252074 |
| LOXL2 | lysyl oxidase-like 2 | 0.0249817 |
| ECE1 | endothelin converting enzyme 1 | 0.0246926 |
| EHBP1 | EH domain binding protein 1 | 0.0246642 |
| MYO10 | myosin X | 0.0246152 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.0245068 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0243455 |
| DSG2 | desmoglein 2 | 0.0243201 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0240653 |
| RPS6 | ribosomal protein S6 | 0.024017 |
| KSR1 | kinase suppressor of ras 1 | 0.0237643 |
| PLIN2 | perilipin 2 | 0.0236664 |
| FNIP2 | folliculin interacting protein 2 | 0.0236611 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0236181 |
| FHL2 | four and a half LIM domains 2 | 0.0232297 |
| SVIL | supervillin | 0.0229088 |
| ITGAV | integrin, alpha V | 0.0228236 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0228096 |
| NAV1 | neuron navigator 1 | 0.0224604 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0224474 |
| LIPG | lipase, endothelial | 0.0223729 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0222394 |
| KYNU | kynureninase | 0.0221935 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0219841 |
| ANXA10 | annexin A10 | 0.0219067 |
| ANGPTL4 | angiopoietin-like 4 | 0.021468 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.0210941 |
| CDCP1 | CUB domain containing protein 1 | 0.0209568 |
| PTK2 | protein tyrosine kinase 2 | 0.0209505 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0208994 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0208916 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | 0.0208323 |
| B2M | beta-2-microglobulin | 0.0208131 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0207442 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | 0.0206662 |
| IL6ST | interleukin 6 signal transducer | 0.0204134 |
| FHIT | fragile histidine triad | 0.020329 |
| AADAC | arylacetamide deacetylase | 0.0203062 |
| RPS12 | ribosomal protein S12 | 0.0202136 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0200891 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0200778 |
| TOP6BL | TOP6B like initiator of meiotic double strand breaks | 0.020049 |
| PALLD | palladin, cytoskeletal associated protein | 0.0198846 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0197895 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0197434 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0197305 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0196762 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0196384 |
| SAMD9L | sterile alpha motif domain containing 9-like | 0.0195132 |
| NRDC | nardilysin convertase | 0.0194879 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | -0.131479 |
| TMSB10 | thymosin beta 10 | -0.117578 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.102363 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0999584 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0981579 |
| USP34 | ubiquitin specific peptidase 34 | -0.0879241 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0798521 |
| RBM39 | RNA binding motif protein 39 | -0.07617 |
| OSMR | oncostatin M receptor | -0.0760359 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0752175 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0707606 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0687611 |
| CDH13 | cadherin 13 | -0.0682926 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0681791 |
| GPC6 | glypican 6 | -0.0630665 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0618514 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0606936 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0598065 |
| LOX | lysyl oxidase | -0.0536581 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0512646 |
| COPA | coatomer protein complex, subunit alpha | -0.0497657 |
| EGR1 | early growth response 1 | -0.0487896 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0474057 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0472876 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0454553 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0452339 |
| FTL | ferritin, light polypeptide | -0.0432372 |
| COL12A1 | collagen, type XII, alpha 1 | -0.0428546 |
| PCBP2 | poly(rC) binding protein 2 | -0.0422387 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0421632 |
| GOLGA4 | golgin A4 | -0.0421496 |
| TNNC1 | troponin C type 1 (slow) | -0.0411256 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.040211 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0401217 |
| MORF4L2 | mortality factor 4 like 2 | -0.0394888 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0374363 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0371117 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0369321 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0367479 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0365936 |
| PID1 | phosphotyrosine interaction domain containing 1 | -0.0365305 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0362778 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0359395 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0356787 |
| ARF4 | ADP-ribosylation factor 4 | -0.0354286 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0353548 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0352556 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0351901 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0349939 |
| SBF2 | SET binding factor 2 | -0.0343778 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0343471 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0342322 |
| COG5 | component of oligomeric golgi complex 5 | -0.0341445 |
| FAM20C | family with sequence similarity 20, member C | -0.0338233 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0337366 |
| PCNX1 | pecanex 1 | -0.0332248 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0332046 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0329234 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0320812 |
| CD44 | CD44 molecule (Indian blood group) | -0.031982 |
| MCL1 | myeloid cell leukemia 1 | -0.0319719 |
| NRG1 | neuregulin 1 | -0.031926 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0314531 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0311428 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0311296 |
| PARD3 | par-3 family cell polarity regulator | -0.0310994 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | -0.0305346 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0299509 |
| SRP54 | signal recognition particle 54kDa | -0.02991 |
| CD109 | CD109 molecule | -0.0298779 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0298266 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0297344 |
| POTEF | POTE ankyrin domain family, member F | -0.0289883 |
| TMEM263 | transmembrane protein 263 | -0.0288181 |
| HDLBP | high density lipoprotein binding protein | -0.0287815 |
| HDAC4 | histone deacetylase 4 | -0.0287424 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | -0.0282804 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0280965 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0278261 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0276845 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0269551 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.02686 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0268372 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0268229 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0263187 |
| CTNNBL1 | catenin, beta like 1 | -0.0262536 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.026102 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0259199 |
| ATF6 | activating transcription factor 6 | -0.0258643 |
| CDK17 | cyclin-dependent kinase 17 | -0.0257983 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0257432 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0256087 |
| MYO1B | myosin IB | -0.025527 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0254474 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0253652 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0250775 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | -0.0249759 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0247793 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0244024 |
| USP3 | ubiquitin specific peptidase 3 | -0.0242535 |
