| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Azithromycin (hydrate) perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Azithromycin (hydrate)_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.319107 |
| MT2A | metallothionein 2A | 0.249155 |
| PM20D1 | peptidase M20 domain containing 1 | 0.104851 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0897931 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0810987 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0777006 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0748143 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0699518 |
| GOLGA4 | golgin A4 | 0.0666083 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0661858 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0573088 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0540912 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0539285 |
| RPS12 | ribosomal protein S12 | 0.0514777 |
| STC1 | stanniocalcin 1 | 0.0510401 |
| VMP1 | vacuole membrane protein 1 | 0.0506097 |
| RPS6 | ribosomal protein S6 | 0.0485346 |
| KIF5B | kinesin family member 5B | 0.0472295 |
| RPS2 | ribosomal protein S2 | 0.0467456 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0457738 |
| RPS8 | ribosomal protein S8 | 0.045446 |
| MSN | moesin | 0.0441164 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0440033 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0424802 |
| MCL1 | myeloid cell leukemia 1 | 0.0422852 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0414543 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0402161 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0398278 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0376157 |
| FLNB | filamin B, beta | 0.0352227 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0337283 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0336928 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0332933 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0331455 |
| IL6 | interleukin 6 | 0.0331045 |
| LAMC2 | laminin, gamma 2 | 0.0328796 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0324327 |
| TOP1 | topoisomerase (DNA) I | 0.0319053 |
| RBM25 | RNA binding motif protein 25 | 0.0317182 |
| SETD5 | SET domain containing 5 | 0.0314915 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0307549 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0305987 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | 0.0305295 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0303836 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0300912 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0299354 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0297411 |
| TMF1 | TATA element modulatory factor 1 | 0.0291097 |
| RPL37A | ribosomal protein L37a | 0.028846 |
| PLS3 | plastin 3 | 0.0286684 |
| NEMF | nuclear export mediator factor | 0.028472 |
| SLMAP | sarcolemma associated protein | 0.0283584 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | 0.0283476 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0282067 |
| JMJD1C | jumonji domain containing 1C | 0.0278224 |
| CLU | clusterin | 0.0271942 |
| CDCP1 | CUB domain containing protein 1 | 0.0271841 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0270975 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0266642 |
| TPR | translocated promoter region, nuclear basket protein | 0.0263935 |
| H1-2 | H1.2 linker histone, cluster member | 0.0257862 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0256062 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0255576 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.025416 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0253303 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0251811 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0248773 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0248513 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha | 0.0247837 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0244611 |
| FAM107B | family with sequence similarity 107, member B | 0.0242168 |
| HLA-B | major histocompatibility complex, class I, B | 0.0241052 |
| PNN | pinin, desmosome associated protein | 0.0240807 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0240485 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0237871 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0237134 |
| DDX24 | DEAD (Asp-Glu-Ala-Asp) box helicase 24 | 0.0235722 |
| PYGL | phosphorylase, glycogen, liver | 0.0233545 |
| SOS2 | son of sevenless homolog 2 (Drosophila) | 0.0233494 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0231275 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0230486 |
| TERF2IP | telomeric repeat binding factor 2, interacting protein | 0.022733 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0226441 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0226059 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0225736 |
| RBM6 | RNA binding motif protein 6 | 0.0225331 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0223242 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0221036 |
| SUPT16H | suppressor of Ty 16 homolog (S. cerevisiae) | 0.0219159 |
| ANXA5 | annexin A5 | 0.0218662 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.021728 |
| NEK7 | NIMA-related kinase 7 | 0.0216678 |
| TASOR2 | transcription activation suppressor family member 2 | 0.0214815 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.021464 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0214148 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0213811 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0212693 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.0212055 |
| SNX14 | sorting nexin 14 | 0.0210525 |
| KIF13A | kinesin family member 13A | 0.0208808 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.191539 |
| TXNRD1 | thioredoxin reductase 1 | -0.10929 |
| FTL | ferritin, light polypeptide | -0.104204 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0963772 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0938953 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0934121 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0886018 |
| PKM | pyruvate kinase, muscle | -0.082581 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0805936 |
| IGF2 | insulin-like growth factor 2 | -0.0787238 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0685911 |
| BICC1 | BicC family RNA binding protein 1 | -0.0681017 |
| RPL19 | ribosomal protein L19 | -0.0657058 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.0592167 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0584061 |
| RPL4 | ribosomal protein L4 | -0.0576391 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0565691 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0554677 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0511551 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0477535 |
| CMIP | c-Maf inducing protein | -0.047743 |
| VIM | vimentin | -0.0475318 |
| PTMA | prothymosin, alpha | -0.0444263 |
| EFNA5 | ephrin-A5 | -0.0438376 |
| THBS1 | thrombospondin 1 | -0.0433545 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0424521 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0420454 |
| ANXA2 | annexin A2 | -0.0418851 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.041885 |
| YBX1 | Y box binding protein 1 | -0.0417287 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0413631 |
| AHNAK | AHNAK nucleoprotein | -0.0408757 |
| USP34 | ubiquitin specific peptidase 34 | -0.0406902 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0406134 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0399579 |
| RPL35A | ribosomal protein L35a | -0.0398926 |
| FGB | fibrinogen beta chain | -0.0391347 |
| DENND4A | DENN/MADD domain containing 4A | -0.0386495 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0383254 |
| TMEM123 | transmembrane protein 123 | -0.0380985 |
| FLNA | filamin A, alpha | -0.0380358 |
| APP | amyloid beta (A4) precursor protein | -0.0377497 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0374583 |
| FNDC3B | fibronectin type III domain containing 3B | -0.037398 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0373061 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0369929 |
| NEGR1 | neuronal growth regulator 1 | -0.0368347 |
| DST | dystonin | -0.0361595 |
| UTRN | utrophin | -0.0359002 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0357704 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0354156 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0353074 |
| PTK2 | protein tyrosine kinase 2 | -0.035301 |
| GLIS3 | GLIS family zinc finger 3 | -0.0350321 |
| GNAS | GNAS complex locus | -0.0347634 |
| ASPH | aspartate beta-hydroxylase | -0.0345948 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.034555 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0339104 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0339049 |
| RPS21 | ribosomal protein S21 | -0.0332053 |
| RPS5 | ribosomal protein S5 | -0.0329351 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0329306 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.032472 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0322134 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | -0.0319653 |
| EGR1 | early growth response 1 | -0.0318938 |
| ACTG1 | actin gamma 1 | -0.0318069 |
| CYRIB | CYFIP related Rac1 interactor B | -0.0312344 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0311939 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0310867 |
| ECT2 | epithelial cell transforming 2 | -0.0307489 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0295397 |
| RPL23 | ribosomal protein L23 | -0.0294161 |
| KHDC4 | KH domain containing 4, pre-mRNA splicing factor | -0.0293998 |
| PFN1 | profilin 1 | -0.029257 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0292513 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0292425 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0290232 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0288424 |
| RPL7 | ribosomal protein L7 | -0.0288214 |
| FAM168A | family with sequence similarity 168, member A | -0.0288076 |
| FGG | fibrinogen gamma chain | -0.0283983 |
| RPS24 | ribosomal protein S24 | -0.0281066 |
| OSMR | oncostatin M receptor | -0.0275134 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0275102 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0274306 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0270168 |
| AK1 | adenylate kinase 1 | -0.0269 |
| AHR | aryl hydrocarbon receptor | -0.0266029 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.0259976 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0258253 |
| OLA1 | Obg-like ATPase 1 | -0.0257301 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0257166 |
| SVIL | supervillin | -0.0256028 |
| LMNA | lamin A/C | -0.0254733 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0254516 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0254442 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0252655 |
| RNF213 | ring finger protein 213 | -0.0250992 |
| NPR2 | natriuretic peptide receptor 2 | -0.0250852 |
