| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Azithromycin (hydrate) perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Azithromycin (hydrate)_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYO1E | myosin IE | 0.1704 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.093002 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0915116 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0897115 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0840117 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0821242 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0774739 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0774342 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0769802 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0763666 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.075469 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0749752 |
| AREG | amphiregulin | 0.0714327 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0706198 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0699451 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0696684 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0692283 |
| RNF149 | ring finger protein 149 | 0.0675971 |
| SON | SON DNA binding protein | 0.0671888 |
| LAMA4 | laminin, alpha 4 | 0.0658596 |
| VMP1 | vacuole membrane protein 1 | 0.0623637 |
| SETX | senataxin | 0.0614063 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0604882 |
| ITGA6 | integrin, alpha 6 | 0.0603474 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0578569 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0566597 |
| MT2A | metallothionein 2A | 0.0561156 |
| CPE | carboxypeptidase E | 0.055855 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0556664 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0553303 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0551253 |
| DSG2 | desmoglein 2 | 0.0546004 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0538825 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0535085 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0530469 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0526181 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0510671 |
| PTGES2 | prostaglandin E synthase 2 | 0.0509223 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.050884 |
| MCL1 | myeloid cell leukemia 1 | 0.0505067 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.050295 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0501786 |
| BPTF | bromodomain PHD finger transcription factor | 0.0501238 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0499595 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0497301 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0492486 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0489308 |
| PCBP2 | poly(rC) binding protein 2 | 0.0480352 |
| RPL31 | ribosomal protein L31 | 0.0479131 |
| ATP11A | ATPase, class VI, type 11A | 0.047797 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0473016 |
| UBE3C | ubiquitin protein ligase E3C | 0.0472129 |
| SEC63 | SEC63 homolog (S. cerevisiae) | 0.0466919 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0465802 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0463358 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0463047 |
| PHIP | pleckstrin homology domain interacting protein | 0.0460422 |
| FN1 | fibronectin 1 | 0.0460396 |
| RPS12 | ribosomal protein S12 | 0.0460301 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0459021 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0458602 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0458222 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0444684 |
| CALR | calreticulin | 0.0444258 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0436911 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0434931 |
| CALCA | calcitonin-related polypeptide alpha | 0.0433453 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0432599 |
| CERT1 | ceramide transporter 1 | 0.0426945 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0425813 |
| KDM3B | lysine (K)-specific demethylase 3B | 0.0423843 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0421686 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0419505 |
| SMYD3 | SET and MYND domain containing 3 | 0.0418623 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0418601 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0417509 |
| PLK2 | polo-like kinase 2 | 0.0416237 |
| TPD52 | tumor protein D52 | 0.0415207 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.041461 |
| NAV1 | neuron navigator 1 | 0.041349 |
| VEGFA | vascular endothelial growth factor A | 0.0410524 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0410097 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0409681 |
| DSPP | dentin sialophosphoprotein | 0.0406236 |
| TPM3 | tropomyosin 3 | 0.040401 |
| CEP350 | centrosomal protein 350kDa | 0.0402309 |
| HOOK3 | hook microtubule-tethering protein 3 | 0.0400254 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0399262 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0398877 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0397914 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.039026 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0389933 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | 0.0389309 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0388773 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0384631 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0383693 |
| N4BP1 | NEDD4 binding protein 1 | 0.0383218 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0382304 |
| TMOD3 | tropomodulin 3 (ubiquitous) | 0.0381415 |
| UMAD1 | UBAP1-MVB12-associated (UMA) domain containing 1 | 0.0380601 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | -0.0990709 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0881323 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0869173 |
| OGA | O-GlcNAcase | -0.0840304 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0796191 |
| PTMA | prothymosin, alpha | -0.0755224 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0748619 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | -0.0747812 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0664991 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0643042 |
| ATOSA | atos homolog A | -0.0640164 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0633576 |
| TNRC18 | trinucleotide repeat containing 18 | -0.0630816 |
| ZNF292 | zinc finger protein 292 | -0.0628901 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0623397 |
| ZNF638 | zinc finger protein 638 | -0.0580646 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0575038 |
| TBL1X | transducin (beta)-like 1X-linked | -0.0571011 |
| LAMB3 | laminin, beta 3 | -0.0569387 |
| TJP1 | tight junction protein 1 | -0.0567603 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0564661 |
| NAV2 | neuron navigator 2 | -0.0562908 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0553569 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0552427 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0551115 |
| AHNAK | AHNAK nucleoprotein | -0.0543462 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0534206 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0521086 |
| ERBIN | erbb2 interacting protein | -0.0511107 |
| RUNX1 | runt-related transcription factor 1 | -0.0507424 |
| KIF13B | kinesin family member 13B | -0.0497059 |
| RBM47 | RNA binding motif protein 47 | -0.0496172 |
| JMJD1C | jumonji domain containing 1C | -0.0487836 |
| FMNL2 | formin-like 2 | -0.0477823 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0477665 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0475146 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0468952 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.046749 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0464277 |
| MUC16 | mucin 16, cell surface associated | -0.0459611 |
| MEF2A | myocyte enhancer factor 2A | -0.0459599 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0457565 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0456624 |
| RBM39 | RNA binding motif protein 39 | -0.0454651 |
| SVIL | supervillin | -0.0453018 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0450645 |
| H3-3B | H3.3 histone B | -0.0450534 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.044962 |
| SLC12A6 | solute carrier family 12 (potassium/chloride transporter), member 6 | -0.0439868 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0438469 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0438124 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0431162 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0422196 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0418635 |
| PARD3 | par-3 family cell polarity regulator | -0.0414717 |
| PHF3 | PHD finger protein 3 | -0.0414478 |
| KYNU | kynureninase | -0.0414209 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0411288 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0410646 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0408414 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0406861 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0405732 |
| SQSTM1 | sequestosome 1 | -0.0404015 |
| SIK3 | SIK family kinase 3 | -0.040253 |
| SSH2 | slingshot protein phosphatase 2 | -0.0400068 |
| NBEA | neurobeachin | -0.0399065 |
| YAP1 | Yes-associated protein 1 | -0.0397975 |
| WDFY2 | WD repeat and FYVE domain containing 2 | -0.0397387 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0396855 |
| KATNBL1 | katanin p80 subunit B-like 1 | -0.039625 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0395739 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0393114 |
| ETV6 | ets variant 6 | -0.0391934 |
| TRIM33 | tripartite motif containing 33 | -0.0391585 |
| USP3 | ubiquitin specific peptidase 3 | -0.038952 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0388155 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0387057 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0386902 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0383652 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | -0.0381781 |
| ABHD17C | abhydrolase domain containing 17C | -0.0381767 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0379628 |
| TUSC3 | tumor suppressor candidate 3 | -0.0376149 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | -0.0375963 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0374547 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0368144 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.036804 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0359027 |
| CFDP1 | craniofacial development protein 1 | -0.03574 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.035546 |
| RIOK3 | RIO kinase 3 | -0.0354079 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0353281 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0352081 |
| UBAP1 | ubiquitin associated protein 1 | -0.0349255 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0348778 |
| SMOC1 | SPARC related modular calcium binding 1 | -0.0346578 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.0346402 |
| HOOK2 | hook microtubule-tethering protein 2 | -0.0346147 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0345503 |
| PLEC | plectin | -0.0345121 |
