| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Azithromycin (hydrate) perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Azithromycin (hydrate)_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.218968 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.137943 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.115984 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0918054 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0698207 |
| MCL1 | myeloid cell leukemia 1 | 0.0692453 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0689095 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0632497 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0597312 |
| YBX3 | Y box binding protein 3 | 0.0595299 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0534301 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0529875 |
| VMP1 | vacuole membrane protein 1 | 0.0499602 |
| RPS12 | ribosomal protein S12 | 0.0497481 |
| TXNRD1 | thioredoxin reductase 1 | 0.0435995 |
| RPS8 | ribosomal protein S8 | 0.0432663 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0421083 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0413458 |
| INTS6 | integrator complex subunit 6 | 0.0410159 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0407697 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0405533 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0396962 |
| TMEM41B | transmembrane protein 41B | 0.0396395 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0373868 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0363317 |
| RPS2 | ribosomal protein S2 | 0.0353061 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0349597 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0346426 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0342444 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0332543 |
| HOMER1 | homer scaffolding protein 1 | 0.0331674 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0315233 |
| RPS29 | ribosomal protein S29 | 0.0314582 |
| YAP1 | Yes-associated protein 1 | 0.0313413 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0304203 |
| NABP1 | nucleic acid binding protein 1 | 0.0303718 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0301988 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0301623 |
| FBXO11 | F-box protein 11 | 0.0300974 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0296532 |
| CDK17 | cyclin-dependent kinase 17 | 0.029016 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.028496 |
| RPS3 | ribosomal protein S3 | 0.0283011 |
| IPO7 | importin 7 | 0.0282854 |
| RPS7 | ribosomal protein S7 | 0.0280486 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0276095 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0267456 |
| JMJD1C | jumonji domain containing 1C | 0.0266309 |
| MYPN | myopalladin | 0.0261884 |
| CAPRIN2 | caprin family member 2 | 0.0257474 |
| NRG1 | neuregulin 1 | 0.0256359 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0252111 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0246089 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0244425 |
| RPS10 | ribosomal protein S10 | 0.0244399 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0243406 |
| RPL21 | ribosomal protein L21 | 0.0242288 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0241437 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0240351 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0239748 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0235395 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0233067 |
| RRM2 | ribonucleotide reductase M2 | 0.0232725 |
| PRPF38B | pre-mRNA processing factor 38B | 0.0230662 |
| BRD2 | bromodomain containing 2 | 0.0229257 |
| TPI1 | triosephosphate isomerase 1 | 0.022776 |
| FERMT2 | fermitin family member 2 | 0.0226614 |
| R3HDM2 | R3H domain containing 2 | 0.0223777 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0222176 |
| CTTNBP2NL | CTTNBP2 N-terminal like | 0.0216443 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0213128 |
| STC1 | stanniocalcin 1 | 0.0212721 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0212453 |
| RCOR1 | REST corepressor 1 | 0.0210052 |
| RPL23 | ribosomal protein L23 | 0.020931 |
| RPS17 | ribosomal protein S17 | 0.0208159 |
| ASPH | aspartate beta-hydroxylase | 0.0204657 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.020381 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.020342 |
| CD164 | CD164 molecule, sialomucin | 0.020339 |
| MYO10 | myosin X | 0.0201408 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0200341 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0200312 |
| RPS23 | ribosomal protein S23 | 0.0199878 |
| RPL37A | ribosomal protein L37a | 0.0193758 |
| SLC25A3 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 | 0.019367 |
| GPHN | gephyrin | 0.0192818 |
| TRIM59 | tripartite motif containing 59 | 0.0192407 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0191484 |
| STAU1 | staufen double-stranded RNA binding protein 1 | 0.0191113 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0190238 |
| C6ORF62 | chromosome 6 open reading frame 62 | 0.0190234 |
| PNN | pinin, desmosome associated protein | 0.0189405 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0188787 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0188619 |
| RNF145 | ring finger protein 145 | 0.0187442 |
| PLCB4 | phospholipase C, beta 4 | 0.0186011 |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog | 0.0185038 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0182976 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0182565 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.165948 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.154537 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.129265 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.114293 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0924127 |
| COPA | coatomer protein complex, subunit alpha | -0.0852066 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0801702 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0800129 |
| VIM | vimentin | -0.0777501 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0776873 |
| TMSB10 | thymosin beta 10 | -0.074644 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0699468 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0686164 |
| RAD51B | RAD51 paralog B | -0.0636824 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0625278 |
| PTMA | prothymosin, alpha | -0.0592454 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0566177 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0553285 |
| EGFR | epidermal growth factor receptor | -0.0535495 |
| RSF1 | remodeling and spacing factor 1 | -0.0534048 |
| ATXN1 | ataxin 1 | -0.0529694 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0522021 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0511868 |
| CANX | calnexin | -0.0511792 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0502254 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0478157 |
| PYGL | phosphorylase, glycogen, liver | -0.0474432 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0470223 |
| RNF213 | ring finger protein 213 | -0.0460437 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0453704 |
| RPL35A | ribosomal protein L35a | -0.0447909 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0446441 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0438279 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0430997 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0427707 |
| POTEF | POTE ankyrin domain family, member F | -0.0415772 |
| IGF2 | insulin-like growth factor 2 | -0.0415163 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0413251 |
| PDE10A | phosphodiesterase 10A | -0.0412853 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0412223 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0403442 |
| PKM | pyruvate kinase, muscle | -0.0398447 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0396906 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0389926 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0384989 |
| RYR3 | ryanodine receptor 3 | -0.0384575 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0382181 |
| OSMR | oncostatin M receptor | -0.0372353 |
| ENO1 | enolase 1, (alpha) | -0.0358843 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | -0.0358831 |
| CALR | calreticulin | -0.0349905 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0347192 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0346606 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0339442 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0334552 |
| HELZ | helicase with zinc finger | -0.0334025 |
| USP34 | ubiquitin specific peptidase 34 | -0.0331461 |
| EGR1 | early growth response 1 | -0.0329518 |
| PTK2 | protein tyrosine kinase 2 | -0.0323939 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0323561 |
| HDGF | hepatoma-derived growth factor | -0.0321695 |
| GNAS | GNAS complex locus | -0.0321417 |
| PFN1 | profilin 1 | -0.0316192 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0314104 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0312616 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0311764 |
| BBX | bobby sox homolog (Drosophila) | -0.0311603 |
| MAP4 | microtubule-associated protein 4 | -0.031145 |
| PHF21A | PHD finger protein 21A | -0.0310205 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0309657 |
| HMGA2 | high mobility group AT-hook 2 | -0.0307182 |
| FMN1 | formin 1 | -0.0306571 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0302373 |
| WDR45B | WD repeat domain 45B | -0.0300695 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0300419 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0299666 |
| SBF2 | SET binding factor 2 | -0.0297358 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0296616 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0295424 |
| SMAD3 | SMAD family member 3 | -0.0293423 |
| TMEM165 | transmembrane protein 165 | -0.0293079 |
| HLA-B | major histocompatibility complex, class I, B | -0.0293012 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0289787 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | -0.0289161 |
| PREPL | prolyl endopeptidase-like | -0.0288449 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0287206 |
| ZNF148 | zinc finger protein 148 | -0.0282323 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0282302 |
| FCHSD2 | FCH and double SH3 domains 2 | -0.028212 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0281212 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0280613 |
| YBX1 | Y box binding protein 1 | -0.0279154 |
| ENOSF1 | enolase superfamily member 1 | -0.0276674 |
| LDHA | lactate dehydrogenase A | -0.0273756 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | -0.0273014 |
| TPM4 | tropomyosin 4 | -0.0271912 |
| EHBP1 | EH domain binding protein 1 | -0.0271291 |
| ZNF207 | zinc finger protein 207 | -0.0269361 |
| MORF4L2 | mortality factor 4 like 2 | -0.0268043 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0267698 |
