| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Azithromycin (hydrate) perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Azithromycin (hydrate)_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.132756 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.126412 |
| FTL | ferritin, light polypeptide | 0.0946002 |
| DSPP | dentin sialophosphoprotein | 0.0919073 |
| MSN | moesin | 0.0792279 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0554678 |
| TXNIP | thioredoxin interacting protein | 0.052848 |
| RPS6 | ribosomal protein S6 | 0.0523 |
| MT2A | metallothionein 2A | 0.0484385 |
| VEGFA | vascular endothelial growth factor A | 0.0475151 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0458761 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0456775 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0445929 |
| RNF145 | ring finger protein 145 | 0.0434972 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0430029 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.039387 |
| RBM25 | RNA binding motif protein 25 | 0.0307988 |
| PNN | pinin, desmosome associated protein | 0.0306419 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0299727 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.029852 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.029611 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0281408 |
| RPS2 | ribosomal protein S2 | 0.0280352 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.027389 |
| RPS8 | ribosomal protein S8 | 0.0266725 |
| RPS12 | ribosomal protein S12 | 0.0264019 |
| RPL21 | ribosomal protein L21 | 0.025779 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0257621 |
| DSG2 | desmoglein 2 | 0.0255637 |
| DDX24 | DEAD (Asp-Glu-Ala-Asp) box helicase 24 | 0.0245923 |
| HMGA1 | high mobility group AT-hook 1 | 0.0244708 |
| VMP1 | vacuole membrane protein 1 | 0.0242745 |
| PCM1 | pericentriolar material 1 | 0.0239583 |
| BRD2 | bromodomain containing 2 | 0.0236068 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0235772 |
| RPLP2 | ribosomal protein, large, P2 | 0.0233573 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0233362 |
| DHX36 | DEAH (Asp-Glu-Ala-His) box polypeptide 36 | 0.0233028 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0231923 |
| SET | SET nuclear proto-oncogene | 0.0230669 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0228483 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0224382 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0222263 |
| RIOK3 | RIO kinase 3 | 0.0220861 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0210456 |
| ANXA5 | annexin A5 | 0.0208425 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0205797 |
| DST | dystonin | 0.0201789 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0200313 |
| CD44 | CD44 molecule (Indian blood group) | 0.0198746 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0198186 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0197885 |
| USP6NL | USP6 N-terminal like | 0.0197213 |
| TMF1 | TATA element modulatory factor 1 | 0.0196397 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0194977 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.019415 |
| SLK | STE20-like kinase | 0.0192162 |
| PABPN1 | poly(A) binding protein, nuclear 1 | 0.0188376 |
| RPS19 | ribosomal protein S19 | 0.018788 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0186482 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0185501 |
| OPTN | optineurin | 0.0178056 |
| SEPTIN7 | septin 7 | 0.017752 |
| TPM3 | tropomyosin 3 | 0.017539 |
| SUPT16H | suppressor of Ty 16 homolog (S. cerevisiae) | 0.0173677 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0173207 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0172642 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0172175 |
| TMA7 | translation machinery associated 7 homolog (S. cerevisiae) | 0.0169587 |
| HMGN2 | high mobility group nucleosomal binding domain 2 | 0.0168622 |
| FOSL1 | FOS-like antigen 1 | 0.0166792 |
| GPX4 | glutathione peroxidase 4 | 0.0166035 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0163637 |
| FOXP1 | forkhead box P1 | 0.0163283 |
| EZR | ezrin | 0.0163129 |
| DSTN | destrin (actin depolymerizing factor) | 0.0162801 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0162374 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.016229 |
| MKI67 | marker of proliferation Ki-67 | 0.0162226 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0161264 |
| PCBP2 | poly(rC) binding protein 2 | 0.0160801 |
| RPL8 | ribosomal protein L8 | 0.0159996 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0158389 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.0158274 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0158005 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0157839 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0157572 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0156501 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0155464 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0155155 |
| RPS29 | ribosomal protein S29 | 0.0154444 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0153478 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | 0.0151312 |
| KIF2A | kinesin heavy chain member 2A | 0.0150253 |
| LAMB3 | laminin, beta 3 | 0.0148609 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0148561 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 0.0147719 |
| SNX9 | sorting nexin 9 | 0.0147011 |
| SON | SON DNA binding protein | 0.014611 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0144539 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.204063 |
| FN1 | fibronectin 1 | -0.15474 |
| FNDC3B | fibronectin type III domain containing 3B | -0.150892 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.144932 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.144557 |
| TMSB10 | thymosin beta 10 | -0.134129 |
| GRB10 | growth factor receptor-bound protein 10 | -0.124744 |
| TMSB4X | thymosin beta 4, X-linked | -0.114704 |
| UBC | ubiquitin C | -0.112387 |
| ASPH | aspartate beta-hydroxylase | -0.0867177 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0847482 |
| EFNA5 | ephrin-A5 | -0.0820343 |
| PTMA | prothymosin, alpha | -0.0818384 |
| LDHA | lactate dehydrogenase A | -0.0769419 |
| ACTG1 | actin gamma 1 | -0.0768159 |
| NAV2 | neuron navigator 2 | -0.0694875 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0686872 |
| VCL | vinculin | -0.0686517 |
| GNAS | GNAS complex locus | -0.0673945 |
| ANXA2 | annexin A2 | -0.0670131 |
| PGK1 | phosphoglycerate kinase 1 | -0.0667527 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0662866 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0647086 |
| ARF1 | ADP-ribosylation factor 1 | -0.0640354 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.06339 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0632189 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0624577 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0615602 |
| MYO6 | myosin VI | -0.0610077 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0608517 |
| FNIP1 | folliculin interacting protein 1 | -0.0607797 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0604755 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | -0.0594247 |
| CCND1 | cyclin D1 | -0.0586661 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0583783 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.058345 |
| PLEC | plectin | -0.0555991 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0554058 |
| FBXO34 | F-box protein 34 | -0.0553924 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0529788 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0529161 |
| RPL35A | ribosomal protein L35a | -0.0517133 |
| COPA | coatomer protein complex, subunit alpha | -0.0511621 |
| S100A6 | S100 calcium binding protein A6 | -0.0508091 |
| RPL34 | ribosomal protein L34 | -0.0500058 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0499766 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0499681 |
| RPS24 | ribosomal protein S24 | -0.0485655 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0485597 |
| KRT8 | keratin 8, type II | -0.0485494 |
| AHNAK | AHNAK nucleoprotein | -0.0485342 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0485231 |
| CALU | calumenin | -0.0483506 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0473015 |
| CANX | calnexin | -0.0472905 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0472265 |
| CD109 | CD109 molecule | -0.0467391 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0464753 |
| EPCAM | epithelial cell adhesion molecule | -0.0461952 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0457016 |
| CDC50A | cell division cycle 50 P4-ATPase accessory subunit A | -0.0456012 |
| MCU | mitochondrial calcium uniporter | -0.0452445 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0441026 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0440826 |
| HDLBP | high density lipoprotein binding protein | -0.0439525 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.043866 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0437528 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0436697 |
| MYO1E | myosin IE | -0.0434956 |
| APP | amyloid beta (A4) precursor protein | -0.0423977 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0420311 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0413859 |
| RPL4 | ribosomal protein L4 | -0.0413658 |
| CD2AP | CD2-associated protein | -0.0413644 |
| LAMC2 | laminin, gamma 2 | -0.0413291 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.04129 |
| RCOR1 | REST corepressor 1 | -0.041169 |
| ARF4 | ADP-ribosylation factor 4 | -0.0408279 |
| HLA-E | major histocompatibility complex, class I, E | -0.0405663 |
| TMEM263 | transmembrane protein 263 | -0.0402244 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0400358 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0399708 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0399673 |
| NDRG1 | N-myc downstream regulated 1 | -0.0398521 |
| CERT1 | ceramide transporter 1 | -0.0395474 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0391114 |
| LMO7 | LIM domain 7 | -0.0388258 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0384912 |
| PKM | pyruvate kinase, muscle | -0.0384068 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0382529 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0381738 |
| NF1 | neurofibromin 1 | -0.0380994 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0377713 |
| CRABP2 | cellular retinoic acid binding protein 2 | -0.0376549 |
| TPM4 | tropomyosin 4 | -0.0376316 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0375601 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0371328 |
| MSI2 | musashi RNA-binding protein 2 | -0.0371148 |
| ATP11A | ATPase, class VI, type 11A | -0.0369936 |
| PLAU | plasminogen activator, urokinase | -0.0368179 |
