| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Azithromycin (hydrate) perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Azithromycin (hydrate)_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EXT1 | exostosin glycosyltransferase 1 | 0.230623 |
| FN1 | fibronectin 1 | 0.226973 |
| HMGA2 | high mobility group AT-hook 2 | 0.127216 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.116479 |
| STC1 | stanniocalcin 1 | 0.109344 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.108483 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.106381 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.102864 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.100914 |
| EHBP1 | EH domain binding protein 1 | 0.0981713 |
| ZNF638 | zinc finger protein 638 | 0.0906803 |
| MYO1E | myosin IE | 0.0891909 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0871554 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0868777 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0821829 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0777075 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0772576 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.077106 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0759803 |
| TMSB10 | thymosin beta 10 | 0.0747014 |
| ASPH | aspartate beta-hydroxylase | 0.0726942 |
| ACTG1 | actin gamma 1 | 0.0716646 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0694388 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0688986 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0671414 |
| RPS6 | ribosomal protein S6 | 0.0658923 |
| CUX1 | cut-like homeobox 1 | 0.0657583 |
| NUMB | numb homolog (Drosophila) | 0.0656399 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0647133 |
| SLC38A2 | solute carrier family 38, member 2 | 0.064348 |
| CD44 | CD44 molecule (Indian blood group) | 0.062736 |
| RPS12 | ribosomal protein S12 | 0.0590241 |
| RASAL2 | RAS protein activator like 2 | 0.0581897 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0581499 |
| RPL12 | ribosomal protein L12 | 0.0572093 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0556505 |
| FOXO1 | forkhead box O1 | 0.0546273 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0534058 |
| YBX3 | Y box binding protein 3 | 0.0527588 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0515091 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0504011 |
| NDRG1 | N-myc downstream regulated 1 | 0.0484303 |
| PCBP3 | poly(rC) binding protein 3 | 0.0483035 |
| RAD51B | RAD51 paralog B | 0.0471724 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0469856 |
| RPL26 | ribosomal protein L26 | 0.0466448 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0448241 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0413437 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0384269 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0372058 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0367189 |
| KDELR2 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 | 0.036432 |
| TOP1 | topoisomerase (DNA) I | 0.0360501 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0358291 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0353054 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0351762 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0346992 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.034069 |
| CCND1 | cyclin D1 | 0.0321113 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0314283 |
| MT2A | metallothionein 2A | 0.0310006 |
| PRELID2 | PRELI domain containing 2 | 0.030633 |
| JMJD1C | jumonji domain containing 1C | 0.0305424 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0304461 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0294968 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0293401 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.028693 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0258255 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0255593 |
| GPC6 | glypican 6 | 0.024932 |
| VIM | vimentin | 0.0244575 |
| INHBA | inhibin, beta A | 0.0215839 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0187975 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0178695 |
| MAP1B | microtubule-associated protein 1B | 0.0158534 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0153535 |
| VMP1 | vacuole membrane protein 1 | 0.0148028 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0143598 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.013846 |
| THOC2 | THO complex 2 | 0.0136117 |
| SQSTM1 | sequestosome 1 | 0.01337 |
| SLMAP | sarcolemma associated protein | 0.0120087 |
| RPL23 | ribosomal protein L23 | 0.0112035 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0109699 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.00889507 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.00846096 |
| MED13 | mediator complex subunit 13 | 0.00804224 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.00784305 |
| RUNX1 | runt-related transcription factor 1 | 0.00751602 |
| ENO1 | enolase 1, (alpha) | 0.00746569 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.00671432 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0045192 |
| EFNA5 | ephrin-A5 | 0.00407548 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.00365212 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.00354764 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.00337535 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.00294672 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.00243671 |
| GOLGA4 | golgin A4 | 0.00216871 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0012818 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.163303 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.144749 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.140735 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.135077 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.130965 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.119449 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.111669 |
| LAMA4 | laminin, alpha 4 | -0.11092 |
| PTMA | prothymosin, alpha | -0.103827 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.103781 |
| PRKCA | protein kinase C, alpha | -0.102959 |
| EGFR | epidermal growth factor receptor | -0.101344 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.09608 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0958959 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0945115 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0892898 |
| SLTM | SAFB-like, transcription modulator | -0.0826764 |
| RSF1 | remodeling and spacing factor 1 | -0.0823219 |
| PDE10A | phosphodiesterase 10A | -0.0800241 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0772307 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0753783 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.074942 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0718509 |
| RAB10 | RAB10, member RAS oncogene family | -0.0714762 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0693547 |
| SMC5 | structural maintenance of chromosomes 5 | -0.0684859 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0675899 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0673519 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0648824 |
| ANXA2 | annexin A2 | -0.0639605 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0620026 |
| FNIP1 | folliculin interacting protein 1 | -0.0612107 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0608941 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0607701 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0594809 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0589127 |
| FAM13A | family with sequence similarity 13, member A | -0.0562374 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0549112 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0535319 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0533317 |
| SYT1 | synaptotagmin I | -0.0517709 |
| SPAG9 | sperm associated antigen 9 | -0.0515412 |
| GOLGB1 | golgin B1 | -0.0508692 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0488635 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0487847 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.048302 |
| PKM | pyruvate kinase, muscle | -0.0469965 |
| NFIA | nuclear factor I/A | -0.045561 |
| CTBP2 | C-terminal binding protein 2 | -0.0448048 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0439686 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0429561 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0406005 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0400364 |
| USP34 | ubiquitin specific peptidase 34 | -0.0399407 |
| ATXN1 | ataxin 1 | -0.0389892 |
| NAV2 | neuron navigator 2 | -0.0388589 |
| CMIP | c-Maf inducing protein | -0.0379766 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0374789 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0365534 |
| SBF2 | SET binding factor 2 | -0.0362317 |
| PGK1 | phosphoglycerate kinase 1 | -0.0352802 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0350099 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0339295 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.03329 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0320855 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0293386 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0290104 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0289362 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0285652 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0285379 |
| EZR | ezrin | -0.0276975 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0276165 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0271738 |
| HDLBP | high density lipoprotein binding protein | -0.0261873 |
| CARD16 | caspase recruitment domain family, member 16 | -0.0253217 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.024903 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0248662 |
| CANX | calnexin | -0.024403 |
| RPL19 | ribosomal protein L19 | -0.024338 |
| TENM3 | teneurin transmembrane protein 3 | -0.0240099 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0218717 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0209103 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0207251 |
| RPLP1 | ribosomal protein, large, P1 | -0.0178229 |
| FMNL2 | formin-like 2 | -0.0171969 |
| KYNU | kynureninase | -0.0164688 |
| SETD5 | SET domain containing 5 | -0.0126226 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0111713 |
| EGR1 | early growth response 1 | -0.0107717 |
| SMYD3 | SET and MYND domain containing 3 | -0.0104349 |
| VCL | vinculin | -0.0103522 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0102722 |
| RORA | RAR-related orphan receptor A | -0.00982004 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.00890589 |
| INTS6 | integrator complex subunit 6 | -0.00886069 |
| PTK2 | protein tyrosine kinase 2 | -0.00876143 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.00864367 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.00629986 |
| MCL1 | myeloid cell leukemia 1 | -0.00259859 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -9.35341E-4 |
