| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Azithromycin (hydrate) perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Azithromycin (hydrate)_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.12225 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.113078 |
| COL11A1 | collagen, type XI, alpha 1 | 0.11075 |
| CADM2 | cell adhesion molecule 2 | 0.106776 |
| NTM | neurotrimin | 0.0834082 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0754546 |
| DSCAM | Down syndrome cell adhesion molecule | 0.069317 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0675113 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0634982 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0599589 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | 0.0584181 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0565175 |
| PCDH9 | protocadherin 9 | 0.0561364 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0543842 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.0535766 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0517678 |
| ATXN2 | ataxin 2 | 0.0504947 |
| WWOX | WW domain containing oxidoreductase | 0.0503607 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0477537 |
| GSE1 | Gse1 coiled-coil protein | 0.0477305 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0432945 |
| ENO1 | enolase 1, (alpha) | 0.0428239 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0426459 |
| B2M | beta-2-microglobulin | 0.0422486 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0414278 |
| RIGI | RNA sensor RIG-I | 0.0410508 |
| MCL1 | myeloid cell leukemia 1 | 0.0405028 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | 0.0401657 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0396253 |
| MEF2C | myocyte enhancer factor 2C | 0.0394956 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0394121 |
| HECTD4 | HECT domain containing E3 ubiquitin protein ligase 4 | 0.0392825 |
| CDH19 | cadherin 19, type 2 | 0.0388611 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0380305 |
| SSH2 | slingshot protein phosphatase 2 | 0.0379835 |
| FOXP2 | forkhead box P2 | 0.0378193 |
| LRRC4C | leucine rich repeat containing 4C | 0.0375493 |
| INTS6 | integrator complex subunit 6 | 0.036513 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0362288 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0360024 |
| PRELID2 | PRELI domain containing 2 | 0.0357965 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0353832 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0350215 |
| GREB1L | growth regulation by estrogen in breast cancer-like | 0.0348746 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0348573 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0347978 |
| RPS12 | ribosomal protein S12 | 0.0330558 |
| ANK2 | ankyrin 2, neuronal | 0.033032 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.0327915 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0323132 |
| SIRT2 | sirtuin 2 | 0.0322592 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0321842 |
| TENM3 | teneurin transmembrane protein 3 | 0.0317815 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0316383 |
| RBM20 | RNA binding motif protein 20 | 0.0314541 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0314495 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0314055 |
| ERBIN | erbb2 interacting protein | 0.0312426 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | 0.0310729 |
| EP300 | E1A binding protein p300 | 0.0310318 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0308446 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0300038 |
| SRPK2 | SRSF protein kinase 2 | 0.0298386 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0297631 |
| SET | SET nuclear proto-oncogene | 0.0297478 |
| NXN | nucleoredoxin | 0.0295227 |
| PCMTD1 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 | 0.029514 |
| RPS3 | ribosomal protein S3 | 0.0293353 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0292694 |
| EGFR | epidermal growth factor receptor | 0.029068 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.028388 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.028352 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0280691 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0280653 |
| RCOR1 | REST corepressor 1 | 0.028008 |
| USP53 | ubiquitin specific peptidase 53 | 0.027989 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0279802 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | 0.0279724 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0278862 |
| UBC | ubiquitin C | 0.0272794 |
| PCDH7 | protocadherin 7 | 0.0271358 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0269972 |
| SLC44A5 | solute carrier family 44, member 5 | 0.0268969 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | 0.0265726 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0265481 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0262728 |
| PLCB4 | phospholipase C, beta 4 | 0.0261234 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0261225 |
| REST | RE1-silencing transcription factor | 0.0260196 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0257742 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0256256 |
| NEBL | nebulette | 0.0256213 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0253954 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0253656 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0250483 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | 0.0250449 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0249289 |
| ATF7IP | activating transcription factor 7 interacting protein | 0.0249188 |
| CSRNP3 | cysteine-serine-rich nuclear protein 3 | 0.0248644 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0247571 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PEG10 | paternally expressed 10 | -0.15724 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.118341 |
| VIM | vimentin | -0.116009 |
| THBS1 | thrombospondin 1 | -0.101513 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0937794 |
| TMSB4X | thymosin beta 4, X-linked | -0.0905386 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0857596 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0825777 |
| ACTG1 | actin gamma 1 | -0.0783026 |
| ZNF292 | zinc finger protein 292 | -0.0764297 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0728024 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0720974 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0638159 |
| RPS16 | ribosomal protein S16 | -0.0603952 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0557998 |
| EMP1 | epithelial membrane protein 1 | -0.0545559 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0509516 |
| YBX1 | Y box binding protein 1 | -0.0494054 |
| FBL | fibrillarin | -0.0479068 |
| HDAC9 | histone deacetylase 9 | -0.0464731 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0464225 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0460421 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0459035 |
| ANXA2 | annexin A2 | -0.0457117 |
| MTF2 | metal response element binding transcription factor 2 | -0.0451625 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.0448725 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | -0.0445662 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0443925 |
| COL5A2 | collagen, type V, alpha 2 | -0.0443754 |
| MRPS30 | mitochondrial ribosomal protein S30 | -0.044225 |
| MYO10 | myosin X | -0.0431362 |
| TFRC | transferrin receptor | -0.0428689 |
| FAM171B | family with sequence similarity 171, member B | -0.0428687 |
| CLTC | clathrin, heavy chain (Hc) | -0.0425374 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.04234 |
| RAI1 | retinoic acid induced 1 | -0.0415724 |
| PGAP1 | post-GPI attachment to proteins 1 | -0.0414555 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0413858 |
| RFPL4B | ret finger protein-like 4B | -0.0404484 |
| USP3 | ubiquitin specific peptidase 3 | -0.0401576 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0400281 |
| GPC3 | glypican 3 | -0.0398054 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | -0.0383349 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0380369 |
| MATR3 | matrin 3 | -0.0379419 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | -0.0378377 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0376121 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0372101 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0370956 |
| SPIDR | scaffolding protein involved in DNA repair | -0.036534 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0364338 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | -0.0359613 |
| VGLL3 | vestigial-like family member 3 | -0.0359115 |
| RDX | radixin | -0.0357916 |
| RPL12 | ribosomal protein L12 | -0.0357837 |
| ZBTB35 | zinc finger and BTB domain containing 35 | -0.0355861 |
| RHEB | Ras homolog enriched in brain | -0.0354754 |
| ENAH | enabled homolog (Drosophila) | -0.0354178 |
| SLC38A2 | solute carrier family 38, member 2 | -0.034916 |
| RPL5 | ribosomal protein L5 | -0.0348733 |
| TMEM123 | transmembrane protein 123 | -0.0346869 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0346618 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0345832 |
| WDR43 | WD repeat domain 43 | -0.0345535 |
| RPLP0 | ribosomal protein, large, P0 | -0.03435 |
| PPM1B | protein phosphatase, Mg2+/Mn2+ dependent, 1B | -0.033915 |
| RPL35A | ribosomal protein L35a | -0.0334801 |
| CELF1 | CUGBP, Elav-like family member 1 | -0.0330876 |
| CDC73 | cell division cycle 73 | -0.0326885 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0323831 |
| CCT8 | chaperonin containing TCP1, subunit 8 (theta) | -0.0322976 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0322976 |
| ACTN4 | actinin, alpha 4 | -0.0320441 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | -0.0318708 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0311906 |
| CDC50A | cell division cycle 50 P4-ATPase accessory subunit A | -0.0310369 |
| ARHGAP15 | Rho GTPase activating protein 15 | -0.0310187 |
| RPL19 | ribosomal protein L19 | -0.0308189 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0306858 |
| NPR2 | natriuretic peptide receptor 2 | -0.0305597 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.030521 |
| CBX3 | chromobox homolog 3 | -0.0304126 |
| TWSG1 | twisted gastrulation BMP signaling modulator 1 | -0.0303834 |
| UPP1 | uridine phosphorylase 1 | -0.0303081 |
| DST | dystonin | -0.030104 |
| RPL6 | ribosomal protein L6 | -0.0299664 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0298354 |
| ATG5 | autophagy related 5 | -0.0295531 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | -0.0293844 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0292104 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0291533 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0286742 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0285862 |
| SRP54 | signal recognition particle 54kDa | -0.0285814 |
| RPS13 | ribosomal protein S13 | -0.0285703 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0283712 |
| RPL4 | ribosomal protein L4 | -0.0283508 |
| PAICS | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase | -0.0280473 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0280276 |
| PRPF8 | pre-mRNA processing factor 8 | -0.0280123 |
