| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Azithromycin (hydrate) perturbation in PANC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Azithromycin (hydrate)_PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.532917 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.13027 |
| ZFP36 | ZFP36 ring finger protein | 0.108573 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.105047 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0839783 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0831856 |
| RPS12 | ribosomal protein S12 | 0.0820063 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0785441 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0751467 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0649982 |
| JMJD1C | jumonji domain containing 1C | 0.0604022 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0599164 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0598235 |
| RPS2 | ribosomal protein S2 | 0.0594532 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0568296 |
| VMP1 | vacuole membrane protein 1 | 0.055322 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0550314 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0519773 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.050936 |
| SQSTM1 | sequestosome 1 | 0.0508268 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0507691 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0479131 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0477371 |
| TXNRD1 | thioredoxin reductase 1 | 0.0465521 |
| SMAD3 | SMAD family member 3 | 0.0456973 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0452043 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0449076 |
| ASPH | aspartate beta-hydroxylase | 0.0430518 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0428773 |
| RPS6 | ribosomal protein S6 | 0.0423078 |
| ARRDC3 | arrestin domain containing 3 | 0.0414147 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0407386 |
| MKI67 | marker of proliferation Ki-67 | 0.0407285 |
| RPLP2 | ribosomal protein, large, P2 | 0.0407255 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0400233 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0395642 |
| KIF5B | kinesin family member 5B | 0.0388969 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0379489 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0376744 |
| CENPF | centromere protein F, 350/400kDa | 0.0376519 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0372988 |
| PRRC2C | proline-rich coiled-coil 2C | 0.037224 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0359666 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0341327 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0338312 |
| SET | SET nuclear proto-oncogene | 0.0335313 |
| DSTN | destrin (actin depolymerizing factor) | 0.0331318 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0330465 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.031905 |
| GOLGA4 | golgin A4 | 0.0314913 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0311445 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0309795 |
| RPS8 | ribosomal protein S8 | 0.0308824 |
| TMEM41B | transmembrane protein 41B | 0.0304255 |
| SEPTIN7 | septin 7 | 0.0304089 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.029593 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0295226 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.029268 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0285706 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.02842 |
| TPR | translocated promoter region, nuclear basket protein | 0.0284119 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0282942 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0281107 |
| CANX | calnexin | 0.0280944 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0277097 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0276075 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0271715 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0271064 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0270984 |
| ITGAV | integrin, alpha V | 0.0269074 |
| FBL | fibrillarin | 0.0267414 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0265121 |
| ANXA2 | annexin A2 | 0.025877 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0257496 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0255748 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0253788 |
| RPS3 | ribosomal protein S3 | 0.0252961 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0252453 |
| OGA | O-GlcNAcase | 0.025239 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0251612 |
| ANGPTL4 | angiopoietin-like 4 | 0.025153 |
| ANO6 | anoctamin 6 | 0.0250798 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0246007 |
| ZNF292 | zinc finger protein 292 | 0.0245123 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.024496 |
| MSN | moesin | 0.0244903 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0243696 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0242786 |
| RPL21 | ribosomal protein L21 | 0.0242493 |
| CCDC88A | coiled-coil domain containing 88A | 0.0242139 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0238975 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0236437 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0236233 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0233354 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0229946 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | 0.0229317 |
| KMT2A | lysine (K)-specific methyltransferase 2A | 0.0226492 |
| XPO1 | exportin 1 | 0.0225914 |
| MATR3 | matrin 3 | 0.0225042 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0224909 |
| Symbol | Name | Standardized Value |
|---|---|---|
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.138129 |
| TMSB10 | thymosin beta 10 | -0.0918804 |
| VIM | vimentin | -0.0876628 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0868818 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0838532 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0615795 |
| ACTN4 | actinin, alpha 4 | -0.0572176 |
| TNS3 | tensin 3 | -0.048705 |
| VCL | vinculin | -0.0485889 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0466994 |
| EGR1 | early growth response 1 | -0.0455978 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0453853 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.0409251 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0390094 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0374254 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0373123 |
| ATG7 | autophagy related 7 | -0.0326695 |
| CTSD | cathepsin D | -0.0293573 |
| RPL35A | ribosomal protein L35a | -0.0271849 |
| EGFR | epidermal growth factor receptor | -0.0271732 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0261839 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0260911 |
| HMGA2 | high mobility group AT-hook 2 | -0.0254872 |
| FLNA | filamin A, alpha | -0.0250944 |
| AHNAK | AHNAK nucleoprotein | -0.0249352 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0243015 |
| TMEM123 | transmembrane protein 123 | -0.0238286 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0236925 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.02319 |
| NAV2 | neuron navigator 2 | -0.0230988 |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 | -0.0230747 |
| HMGA1 | high mobility group AT-hook 1 | -0.0224889 |
| COL18A1 | collagen, type XVIII, alpha 1 | -0.0224573 |
| NHSL1 | NHS-like 1 | -0.022282 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0221376 |
| RNF213 | ring finger protein 213 | -0.0219084 |
| POTEF | POTE ankyrin domain family, member F | -0.0214778 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0212234 |
| RNF220 | ring finger protein 220 | -0.0204722 |
| ATM | ATM serine/threonine kinase | -0.0203594 |
| MCL1 | myeloid cell leukemia 1 | -0.0198995 |
| RPS24 | ribosomal protein S24 | -0.0187334 |
| L1CAM | L1 cell adhesion molecule | -0.0186366 |
| PFN1 | profilin 1 | -0.0185334 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0177945 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0177124 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0176034 |
| CMIP | c-Maf inducing protein | -0.0174467 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.016992 |
| ZNF546 | zinc finger protein 546 | -0.0169778 |
| DNAH5 | dynein, axonemal, heavy chain 5 | -0.0168887 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0168741 |
| RASAL2 | RAS protein activator like 2 | -0.0168171 |
| BSG | basigin (Ok blood group) | -0.0167943 |
| PMM2 | phosphomannomutase 2 | -0.0166922 |
| ZNF407 | zinc finger protein 407 | -0.0165129 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0160592 |
| NPAS2 | neuronal PAS domain protein 2 | -0.016022 |
| DOCK1 | dedicator of cytokinesis 1 | -0.0159511 |
| RAD51B | RAD51 paralog B | -0.0158386 |
| MTCL1 | microtubule crosslinking factor 1 | -0.0157583 |
| WDR27 | WD repeat domain 27 | -0.0156938 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0156885 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0155576 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.0155497 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0149306 |
| THSD7A | thrombospondin, type I, domain containing 7A | -0.0148343 |
| MORF4L2 | mortality factor 4 like 2 | -0.014803 |
| PSMC4 | proteasome (prosome, macropain) 26S subunit, ATPase, 4 | -0.0147646 |
| CARD18 | caspase recruitment domain family, member 18 | -0.014707 |
| COMMD10 | COMM domain containing 10 | -0.014645 |
| PTMA | prothymosin, alpha | -0.0145837 |
| LAMA5 | laminin, alpha 5 | -0.0145478 |
| INTS6 | integrator complex subunit 6 | -0.0144889 |
| S100A6 | S100 calcium binding protein A6 | -0.0143555 |
| TUBB | tubulin, beta class I | -0.0143442 |
| EIF3K | eukaryotic translation initiation factor 3, subunit K | -0.014311 |
| KRT8 | keratin 8, type II | -0.0142567 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0142096 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0140314 |
| SEPTIN9 | septin 9 | -0.0139561 |
| CD109 | CD109 molecule | -0.0138458 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.013821 |
| UBC | ubiquitin C | -0.0138185 |
| SRSF1 | serine/arginine-rich splicing factor 1 | -0.0137604 |
| PKM | pyruvate kinase, muscle | -0.0137116 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | -0.0135871 |
| RPS5 | ribosomal protein S5 | -0.0135666 |
| RLIM | ring finger protein, LIM domain interacting | -0.0133448 |
| LARP4B | La ribonucleoprotein domain family, member 4B | -0.0132877 |
| HDAC4 | histone deacetylase 4 | -0.0131918 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0130269 |
| NALCN | sodium leak channel, non selective | -0.0130146 |
| PRKCA | protein kinase C, alpha | -0.0129349 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | -0.0129323 |
| EXOC4 | exocyst complex component 4 | -0.012929 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0127449 |
| DIAPH2 | diaphanous-related formin 2 | -0.0126175 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0124293 |
| FNIP1 | folliculin interacting protein 1 | -0.0123755 |
