| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Azithromycin (hydrate) perturbation in RKO cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Azithromycin (hydrate)_RKO drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ARHGAP22 | Rho GTPase activating protein 22 | 0.121867 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.102585 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0945101 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0888011 |
| RPS12 | ribosomal protein S12 | 0.0725732 |
| MCL1 | myeloid cell leukemia 1 | 0.0664694 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.065696 |
| RPS2 | ribosomal protein S2 | 0.0577551 |
| FLNB | filamin B, beta | 0.0563084 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0554906 |
| FRMD4A | FERM domain containing 4A | 0.0553113 |
| ENO1 | enolase 1, (alpha) | 0.0548514 |
| ASPH | aspartate beta-hydroxylase | 0.0545183 |
| RPS27A | ribosomal protein S27a | 0.0536534 |
| UBC | ubiquitin C | 0.0499332 |
| JMJD1C | jumonji domain containing 1C | 0.0476509 |
| HMGA2 | high mobility group AT-hook 2 | 0.0465677 |
| FRMD6 | FERM domain containing 6 | 0.04499 |
| SET | SET nuclear proto-oncogene | 0.0443466 |
| ANK2 | ankyrin 2, neuronal | 0.0441238 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0421521 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.038693 |
| SHANK1 | SH3 and multiple ankyrin repeat domains 1 | 0.0369577 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | 0.036018 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0358809 |
| JUN | jun proto-oncogene | 0.0352112 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0342531 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | 0.0339649 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0338838 |
| VMP1 | vacuole membrane protein 1 | 0.0335285 |
| CAPRIN2 | caprin family member 2 | 0.0332161 |
| SGMS2 | sphingomyelin synthase 2 | 0.0330028 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0325342 |
| TMEM156 | transmembrane protein 156 | 0.0323155 |
| HDAC9 | histone deacetylase 9 | 0.0317743 |
| PHF14 | PHD finger protein 14 | 0.0316254 |
| TM4SF19 | transmembrane 4 L six family member 19 | 0.0307379 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0300097 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0294568 |
| RPL7A | ribosomal protein L7a | 0.0291979 |
| TPM4 | tropomyosin 4 | 0.0284054 |
| RPL37A | ribosomal protein L37a | 0.0282087 |
| RPL9 | ribosomal protein L9 | 0.0280124 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0278619 |
| DGKI | diacylglycerol kinase, iota | 0.0274851 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0268948 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0268744 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0263218 |
| CASP4 | caspase 4, apoptosis-related cysteine peptidase | 0.0255973 |
| TUT7 | terminal uridylyl transferase 7 | 0.0250963 |
| RPS8 | ribosomal protein S8 | 0.0249874 |
| ZC3H12B | zinc finger CCCH-type containing 12B | 0.0246598 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0245867 |
| RPS3 | ribosomal protein S3 | 0.0245397 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0243059 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0242856 |
| RPS25 | ribosomal protein S25 | 0.0239413 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.0238768 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0237057 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0233893 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0233751 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0233441 |
| USP34 | ubiquitin specific peptidase 34 | 0.0232175 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0229994 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0229921 |
| CCDC91 | coiled-coil domain containing 91 | 0.0220248 |
| EFNB2 | ephrin-B2 | 0.0218553 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0216562 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0216288 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0215395 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0215231 |
| DENR | density-regulated protein | 0.0214364 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0213622 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 | 0.0210385 |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) | 0.0206177 |
| RAD51B | RAD51 paralog B | 0.0204277 |
| EFL1 | elongation factor like GTPase 1 | 0.0204277 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0203065 |
| EEA1 | early endosome antigen 1 | 0.0202269 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.0200277 |
| ZNF638 | zinc finger protein 638 | 0.0199902 |
| EXOC4 | exocyst complex component 4 | 0.0198643 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.019851 |
| VEPH1 | ventricular zone expressed PH domain-containing 1 | 0.0197949 |
| PBRM1 | polybromo 1 | 0.0197504 |
| UCHL3 | ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) | 0.019728 |
| WDR26 | WD repeat domain 26 | 0.0197211 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0197149 |
| SOS2 | son of sevenless homolog 2 (Drosophila) | 0.0196535 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0196056 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0194576 |
| ZNF438 | zinc finger protein 438 | 0.0192921 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | 0.0191481 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0190735 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0190448 |
| BPTF | bromodomain PHD finger transcription factor | 0.018995 |
| RPS17 | ribosomal protein S17 | 0.0183885 |
| TMEM41B | transmembrane protein 41B | 0.0183504 |
| NRDC | nardilysin convertase | 0.0180089 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0180077 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.200697 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.161229 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.117297 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.112458 |
| RAD21 | RAD21 homolog (S. pombe) | -0.104105 |
| TTR | transthyretin | -0.0913061 |
| NUP58 | nucleoporin 58 | -0.076275 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0741374 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0719597 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0702556 |
| ZNF292 | zinc finger protein 292 | -0.070119 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.069089 |
| HMGA1 | high mobility group AT-hook 1 | -0.0686764 |
| NDRG1 | N-myc downstream regulated 1 | -0.0641008 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.063682 |
| OLA1 | Obg-like ATPase 1 | -0.0632969 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.062291 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0617021 |
| RLF | rearranged L-myc fusion | -0.0592962 |
| ACTG1 | actin gamma 1 | -0.0592585 |
| PARD3 | par-3 family cell polarity regulator | -0.0592194 |
| DIAPH3 | diaphanous-related formin 3 | -0.0581154 |
| USP3 | ubiquitin specific peptidase 3 | -0.0561627 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0557694 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | -0.0547425 |
| RPL35A | ribosomal protein L35a | -0.054156 |
| GNAS | GNAS complex locus | -0.0537584 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.053754 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0520662 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0510321 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0509175 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0508885 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0506651 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0498396 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0497118 |
| RTN4 | reticulon 4 | -0.0493549 |
| PHIP | pleckstrin homology domain interacting protein | -0.049013 |
| RYBP | RING1 and YY1 binding protein | -0.048713 |
| TXNRD1 | thioredoxin reductase 1 | -0.0486022 |
| PTK2 | protein tyrosine kinase 2 | -0.0482694 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0479189 |
| RBM39 | RNA binding motif protein 39 | -0.0473023 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0472404 |
| STC1 | stanniocalcin 1 | -0.0468919 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0457058 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0448977 |
| SRPK2 | SRSF protein kinase 2 | -0.044151 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0439089 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0435483 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0432407 |
| EGR1 | early growth response 1 | -0.0426773 |
| POU2F1 | POU class 2 homeobox 1 | -0.042145 |
| MKI67 | marker of proliferation Ki-67 | -0.0418927 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0416804 |
| S100A2 | S100 calcium binding protein A2 | -0.0414817 |
| RNF145 | ring finger protein 145 | -0.0414749 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.040725 |
| TMSB10 | thymosin beta 10 | -0.0406042 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0404803 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0404593 |
| RUNX1 | runt-related transcription factor 1 | -0.0399504 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0396465 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0396289 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0394666 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.039415 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0390392 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | -0.038615 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0380487 |
| CCNL1 | cyclin L1 | -0.0379418 |
| FMNL2 | formin-like 2 | -0.0378925 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0376466 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0374006 |
| SETD5 | SET domain containing 5 | -0.0372504 |
| WDR45B | WD repeat domain 45B | -0.0367949 |
| YBX1 | Y box binding protein 1 | -0.0366349 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0364227 |
| RPL13A | ribosomal protein L13a | -0.0361764 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0360643 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | -0.0360202 |
| PFN1 | profilin 1 | -0.0356799 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0355641 |
| RBM25 | RNA binding motif protein 25 | -0.0352377 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0344415 |
| ECT2 | epithelial cell transforming 2 | -0.0343489 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0342384 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0342046 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0337624 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0335937 |
| FOXO3 | forkhead box O3 | -0.0333673 |
| POTEF | POTE ankyrin domain family, member F | -0.033074 |
| TMEM123 | transmembrane protein 123 | -0.0327861 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0326926 |
| PKM | pyruvate kinase, muscle | -0.0326584 |
| SEPTIN7 | septin 7 | -0.0325411 |
| PGK1 | phosphoglycerate kinase 1 | -0.0325305 |
| TCERG1 | transcription elongation regulator 1 | -0.0324307 |
| RPS19 | ribosomal protein S19 | -0.0319659 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0316866 |
| PDS5B | PDS5 cohesin associated factor B | -0.0316087 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.031379 |
