| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Azithromycin (hydrate) perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Azithromycin (hydrate)_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VEGFA | vascular endothelial growth factor A | 0.144329 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.114702 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0981257 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0887227 |
| B2M | beta-2-microglobulin | 0.0874754 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0725456 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0705125 |
| IFI44L | interferon-induced protein 44-like | 0.067881 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0654755 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.063518 |
| STC1 | stanniocalcin 1 | 0.0619112 |
| SMAD3 | SMAD family member 3 | 0.0590523 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.057419 |
| FOSL1 | FOS-like antigen 1 | 0.0553707 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0495738 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0486498 |
| RPS6 | ribosomal protein S6 | 0.0477199 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0450667 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0438203 |
| FHIT | fragile histidine triad | 0.0430024 |
| HDAC9 | histone deacetylase 9 | 0.0422716 |
| SP100 | SP100 nuclear antigen | 0.0406066 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.040096 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0380395 |
| OPTN | optineurin | 0.0359261 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0353379 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.034533 |
| RPS8 | ribosomal protein S8 | 0.0342212 |
| ARL4C | ADP-ribosylation factor-like 4C | 0.0338734 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0332234 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.033057 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0315214 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0314556 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0313526 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0303339 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0299364 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0298751 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0295253 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0291549 |
| MTSS1 | metastasis suppressor 1 | 0.0286353 |
| IL1B | interleukin 1, beta | 0.0277729 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0277012 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0275775 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0275356 |
| MSN | moesin | 0.0275324 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0269875 |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog | 0.0268942 |
| EGR1 | early growth response 1 | 0.0268444 |
| SVIL | supervillin | 0.0263786 |
| SON | SON DNA binding protein | 0.0262798 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0261947 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0260745 |
| RPS12 | ribosomal protein S12 | 0.0260656 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0257514 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0257342 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0256641 |
| XRN1 | 5'-3' exoribonuclease 1 | 0.0256422 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0249979 |
| GPHN | gephyrin | 0.0247196 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0243782 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0242598 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.02386 |
| KIF5B | kinesin family member 5B | 0.0238184 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0237387 |
| KYNU | kynureninase | 0.0237155 |
| AEBP1 | AE binding protein 1 | 0.0237064 |
| ZNF638 | zinc finger protein 638 | 0.0236546 |
| SAMHD1 | SAM domain and HD domain 1 | 0.0236034 |
| NRDC | nardilysin convertase | 0.0230272 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0229619 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0229512 |
| MX1 | MX dynamin-like GTPase 1 | 0.0225696 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.0225035 |
| LPCAT2 | lysophosphatidylcholine acyltransferase 2 | 0.022382 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0223011 |
| BPTF | bromodomain PHD finger transcription factor | 0.022102 |
| EHBP1 | EH domain binding protein 1 | 0.0217934 |
| RPS19 | ribosomal protein S19 | 0.0217768 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0217439 |
| PUM3 | pumilio RNA binding family member 3 | 0.0216873 |
| MED13L | mediator complex subunit 13-like | 0.0216312 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0215115 |
| RBM5 | RNA binding motif protein 5 | 0.0214053 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 0.0213933 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0213408 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0213329 |
| TOP1 | topoisomerase (DNA) I | 0.0213027 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0212842 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0212075 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0211191 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0210331 |
| PTK2 | protein tyrosine kinase 2 | 0.0209439 |
| MYADM | myeloid-associated differentiation marker | 0.0208228 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | 0.0206859 |
| NAV2 | neuron navigator 2 | 0.0206268 |
| TAF1 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa | 0.0204995 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0204243 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0204225 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0204017 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0199233 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.467899 |
| VIM | vimentin | -0.141954 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.127761 |
| PGK1 | phosphoglycerate kinase 1 | -0.120578 |
| COL1A1 | collagen, type I, alpha 1 | -0.0890393 |
| LDHA | lactate dehydrogenase A | -0.0774391 |
| NDRG1 | N-myc downstream regulated 1 | -0.0763056 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0759285 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0698784 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0656867 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0618749 |
| COL5A1 | collagen, type V, alpha 1 | -0.0602983 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0578811 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0567314 |
| HDLBP | high density lipoprotein binding protein | -0.0549961 |
| CD44 | CD44 molecule (Indian blood group) | -0.0542748 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0538397 |
| GLIS3 | GLIS family zinc finger 3 | -0.0533973 |
| AHNAK | AHNAK nucleoprotein | -0.0513471 |
| CDH13 | cadherin 13 | -0.0474944 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0473215 |
| TMSB10 | thymosin beta 10 | -0.047143 |
| PKM | pyruvate kinase, muscle | -0.0469687 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0455563 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0440275 |
| FRMD4A | FERM domain containing 4A | -0.0437542 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0415747 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0402697 |
| PCBP3 | poly(rC) binding protein 3 | -0.039851 |
| RLIM | ring finger protein, LIM domain interacting | -0.0395312 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.039147 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0387054 |
| GNAS | GNAS complex locus | -0.0386728 |
| SEC24D | SEC24 family member D | -0.0384889 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | -0.0372663 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0369245 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0366161 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0360601 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0358521 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0353031 |
| FAM20C | family with sequence similarity 20, member C | -0.0349987 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0346035 |
| TNNC1 | troponin C type 1 (slow) | -0.0342539 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) | -0.0335604 |
| GOLGA4 | golgin A4 | -0.0335213 |
| TFG | TRK-fused gene | -0.0329944 |
| VCL | vinculin | -0.03283 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0326561 |
| H1-0 | H1.0 linker histone | -0.032626 |
| ANXA2 | annexin A2 | -0.0326131 |
| TCF12 | transcription factor 12 | -0.0322023 |
| NRP2 | neuropilin 2 | -0.032095 |
| RASA3 | RAS p21 protein activator 3 | -0.0318823 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0318308 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.031403 |
| TNS3 | tensin 3 | -0.0308244 |
| CALU | calumenin | -0.0307294 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0306983 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0306911 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0304637 |
| NCAM1 | neural cell adhesion molecule 1 | -0.030446 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0301945 |
| ACTN1 | actinin, alpha 1 | -0.0301875 |
| NBAS | neuroblastoma amplified sequence | -0.0300038 |
| TMEM263 | transmembrane protein 263 | -0.0291762 |
| TPM4 | tropomyosin 4 | -0.0290896 |
| PAX3 | paired box 3 | -0.028538 |
| MORF4L2 | mortality factor 4 like 2 | -0.028159 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0280454 |
| COL5A2 | collagen, type V, alpha 2 | -0.0278017 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0277619 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0275967 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | -0.0273259 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0272888 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0271675 |
| COPA | coatomer protein complex, subunit alpha | -0.0270055 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0269039 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0266969 |
| SCFD2 | sec1 family domain containing 2 | -0.0266919 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0266632 |
| FMNL2 | formin-like 2 | -0.0265122 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0265069 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0264445 |
| CD109 | CD109 molecule | -0.0262713 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0259295 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.025668 |
| FBN1 | fibrillin 1 | -0.0255908 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0255721 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0253445 |
| NREP | neuronal regeneration related protein | -0.0252283 |
| FAM107B | family with sequence similarity 107, member B | -0.0252103 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0251378 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | -0.0251345 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.0245834 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0245161 |
| ARHGAP35 | Rho GTPase activating protein 35 | -0.0245092 |
| WNT5A | wingless-type MMTV integration site family, member 5A | -0.0244199 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0242078 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0241402 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | -0.0240409 |
