| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Azithromycin (hydrate) perturbation in SHP-77 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Azithromycin (hydrate)_SHP-77 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| STC1 | stanniocalcin 1 | 0.0971764 |
| INHBA | inhibin, beta A | 0.0749219 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.062872 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0621805 |
| MCL1 | myeloid cell leukemia 1 | 0.0495461 |
| ZFHX3 | zinc finger homeobox 3 | 0.0437429 |
| EFNA5 | ephrin-A5 | 0.0432708 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0423762 |
| ASPH | aspartate beta-hydroxylase | 0.0414607 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0376474 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0358494 |
| IRS2 | insulin receptor substrate 2 | 0.0349981 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0345398 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0303435 |
| PTCHD4 | patched domain containing 4 | 0.030075 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0300568 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | 0.0300462 |
| ANKRD36C | ankyrin repeat domain 36C | 0.0297931 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0284824 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0251615 |
| MT2A | metallothionein 2A | 0.0248947 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.023655 |
| KLHL29 | kelch-like family member 29 | 0.0234073 |
| TOP1 | topoisomerase (DNA) I | 0.0232097 |
| AHI1 | Abelson helper integration site 1 | 0.0230649 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | 0.0228176 |
| BPTF | bromodomain PHD finger transcription factor | 0.0227866 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0223542 |
| DNAJC6 | DnaJ (Hsp40) homolog, subfamily C, member 6 | 0.0210648 |
| FERMT2 | fermitin family member 2 | 0.0210292 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0207851 |
| NCKAP5 | NCK-associated protein 5 | 0.0207225 |
| MAN1A2 | mannosidase, alpha, class 1A, member 2 | 0.0206583 |
| CDK13 | cyclin-dependent kinase 13 | 0.0205883 |
| SCFD2 | sec1 family domain containing 2 | 0.0203932 |
| EGFR | epidermal growth factor receptor | 0.0203615 |
| VMP1 | vacuole membrane protein 1 | 0.0202581 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0201905 |
| BLZF1 | basic leucine zipper nuclear factor 1 | 0.0198531 |
| RORA | RAR-related orphan receptor A | 0.0197329 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | 0.0194352 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.019337 |
| SON | SON DNA binding protein | 0.0193282 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0192066 |
| VCL | vinculin | 0.0189987 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.0186103 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0183599 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0183104 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0179805 |
| NFIB | nuclear factor I/B | 0.0178152 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.017707 |
| ITGB5 | integrin, beta 5 | 0.0175791 |
| CNOT7 | CCR4-NOT transcription complex, subunit 7 | 0.0175443 |
| PMP22 | peripheral myelin protein 22 | 0.0171009 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.0170685 |
| ASCL1 | achaete-scute family bHLH transcription factor 1 | 0.0169751 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.016333 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0163141 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0162967 |
| BRD9 | bromodomain containing 9 | 0.0161996 |
| XRN1 | 5'-3' exoribonuclease 1 | 0.0161863 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0161559 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0161472 |
| MAP7 | microtubule-associated protein 7 | 0.0160721 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0160295 |
| SQSTM1 | sequestosome 1 | 0.0159807 |
| ITSN1 | intersectin 1 (SH3 domain protein) | 0.0159786 |
| FOXP1 | forkhead box P1 | 0.0158901 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0158636 |
| SIL1 | SIL1 nucleotide exchange factor | 0.0158428 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0158201 |
| ERGIC2 | ERGIC and golgi 2 | 0.0156924 |
| TOM1L2 | target of myb1-like 2 (chicken) | 0.015637 |
| DEK | DEK proto-oncogene | 0.0155632 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.0155613 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.0155612 |
| NOL10 | nucleolar protein 10 | 0.0155352 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | 0.015518 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0154658 |
| NBEA | neurobeachin | 0.0154551 |
| ZFP91 | ZFP91 zinc finger protein | 0.0154291 |
| INTS6 | integrator complex subunit 6 | 0.0152688 |
| TAOK1 | TAO kinase 1 | 0.0152542 |
| PLXNA2 | plexin A2 | 0.0151088 |
| SFSWAP | splicing factor, suppressor of white-apricot family | 0.0150937 |
| RNF111 | ring finger protein 111 | 0.0149339 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0148082 |
| NOVA1 | neuro-oncological ventral antigen 1 | 0.0145518 |
| THSD7A | thrombospondin, type I, domain containing 7A | 0.0145514 |
| RDX | radixin | 0.0145238 |
| SFMBT2 | Scm-like with four mbt domains 2 | 0.0144403 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | 0.0143361 |
| TMEM263 | transmembrane protein 263 | 0.0142229 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0142057 |
| PPP4R3B | protein phosphatase 4 regulatory subunit 3B | 0.0140749 |
| LYST | lysosomal trafficking regulator | 0.0140047 |
| FBXO34 | F-box protein 34 | 0.0139194 |
| TBC1D4 | TBC1 domain family, member 4 | 0.0138798 |
| MEF2A | myocyte enhancer factor 2A | 0.0138724 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0138295 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.182643 |
| TENM1 | teneurin transmembrane protein 1 | -0.130698 |
| PDE10A | phosphodiesterase 10A | -0.11226 |
| CALCA | calcitonin-related polypeptide alpha | -0.0938251 |
| VGF | VGF nerve growth factor inducible | -0.0729674 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.069565 |
| CPE | carboxypeptidase E | -0.0684675 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0641891 |
| CENPF | centromere protein F, 350/400kDa | -0.0632694 |
| ENO1 | enolase 1, (alpha) | -0.0603116 |
| CHD7 | chromodomain helicase DNA binding protein 7 | -0.0601198 |
| MKI67 | marker of proliferation Ki-67 | -0.0598268 |
| PKM | pyruvate kinase, muscle | -0.0586984 |
| PEG10 | paternally expressed 10 | -0.0559559 |
| RPL37A | ribosomal protein L37a | -0.0554407 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0544569 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0538413 |
| FTL | ferritin, light polypeptide | -0.0520267 |
| SYT1 | synaptotagmin I | -0.0517582 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0511712 |
| CACNA1D | calcium channel, voltage-dependent, L type, alpha 1D subunit | -0.0509084 |
| RPS25 | ribosomal protein S25 | -0.0507357 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0505537 |
| PITPNM2 | phosphatidylinositol transfer protein, membrane-associated 2 | -0.0502398 |
| RPS6 | ribosomal protein S6 | -0.0478106 |
| NKAIN2 | Na+/K+ transporting ATPase interacting 2 | -0.0471961 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0468806 |
| RTN4 | reticulon 4 | -0.046022 |
| RPLP1 | ribosomal protein, large, P1 | -0.0456996 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0456257 |
| NDRG1 | N-myc downstream regulated 1 | -0.0450372 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.0438992 |
| RPS19 | ribosomal protein S19 | -0.0435913 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0433537 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0417374 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0414281 |
| SEPTIN7 | septin 7 | -0.0409663 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0406766 |
| CHGB | chromogranin B | -0.0403579 |
| PGK1 | phosphoglycerate kinase 1 | -0.0402172 |
| CADM1 | cell adhesion molecule 1 | -0.0399442 |
| KCNB2 | potassium channel, voltage gated Shab related subfamily B, member 2 | -0.0397342 |
| RPL26 | ribosomal protein L26 | -0.0394948 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0393928 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.039375 |
| RPL19 | ribosomal protein L19 | -0.0390237 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0368947 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0368084 |
| NCAM1 | neural cell adhesion molecule 1 | -0.035882 |
| RPL8 | ribosomal protein L8 | -0.0353909 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0347265 |
| MSI2 | musashi RNA-binding protein 2 | -0.0346314 |
| UBA52 | ubiquitin A-52 residue ribosomal protein fusion product 1 | -0.0343383 |
| POTEF | POTE ankyrin domain family, member F | -0.0343085 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0335619 |
| SLC35F4 | solute carrier family 35, member F4 | -0.0330732 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0327247 |
| GSE1 | Gse1 coiled-coil protein | -0.0323331 |
| STMN1 | stathmin 1 | -0.0322612 |
| RPL31 | ribosomal protein L31 | -0.0317056 |
| SLC36A4 | solute carrier family 36 (proton/amino acid symporter), member 4 | -0.0316614 |
| RPS27 | ribosomal protein S27 | -0.0315906 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0315659 |
| RNF213 | ring finger protein 213 | -0.0315366 |
| SMOC1 | SPARC related modular calcium binding 1 | -0.0313761 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0311218 |
| RPL38 | ribosomal protein L38 | -0.0310853 |
| S100A9 | S100 calcium binding protein A9 | -0.0307514 |
| RPL7 | ribosomal protein L7 | -0.0305407 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.030454 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0304366 |
| RPS27A | ribosomal protein S27a | -0.0303631 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0303146 |
| RPS15 | ribosomal protein S15 | -0.0302784 |
| HECTD4 | HECT domain containing E3 ubiquitin protein ligase 4 | -0.0300405 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | -0.0299247 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0297258 |
| RPL23 | ribosomal protein L23 | -0.0296972 |
| MATR3 | matrin 3 | -0.0292754 |
| HELZ | helicase with zinc finger | -0.029081 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0290164 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0289198 |
| RPS14 | ribosomal protein S14 | -0.028887 |
| GOLIM4 | golgi integral membrane protein 4 | -0.0284542 |
| RAD51B | RAD51 paralog B | -0.0284366 |
| PGAP1 | post-GPI attachment to proteins 1 | -0.0283294 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0283083 |
| VAV2 | vav 2 guanine nucleotide exchange factor | -0.0279416 |
| CELF1 | CUGBP, Elav-like family member 1 | -0.027836 |
| RPS20 | ribosomal protein S20 | -0.0277669 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0276974 |
| DGKB | diacylglycerol kinase, beta 90kDa | -0.0275954 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0273357 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.027295 |
| RPS16 | ribosomal protein S16 | -0.0272615 |
| PHIP | pleckstrin homology domain interacting protein | -0.0272233 |
| B2M | beta-2-microglobulin | -0.0270299 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0270114 |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 | -0.0269452 |
| RPS8 | ribosomal protein S8 | -0.026926 |
