| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Azithromycin (hydrate) perturbation in SK-MEL-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Azithromycin (hydrate)_SK-MEL-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.177859 |
| NLGN1 | neuroligin 1 | 0.139252 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.126298 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.120715 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.10697 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0954458 |
| NRG3 | neuregulin 3 | 0.0907282 |
| ENO1 | enolase 1, (alpha) | 0.076417 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0743125 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0674706 |
| B2M | beta-2-microglobulin | 0.0647558 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0613376 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0577433 |
| ANGPTL4 | angiopoietin-like 4 | 0.056822 |
| RPS6 | ribosomal protein S6 | 0.0538044 |
| DST | dystonin | 0.0478646 |
| LSAMP | limbic system-associated membrane protein | 0.047287 |
| MSN | moesin | 0.0465153 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0458414 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0451834 |
| RPS12 | ribosomal protein S12 | 0.0444679 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0442361 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0438269 |
| ASPH | aspartate beta-hydroxylase | 0.0430218 |
| PTMA | prothymosin, alpha | 0.0422543 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0400954 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0389884 |
| BBX | bobby sox homolog (Drosophila) | 0.0389142 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.038497 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0383019 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0371658 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0365374 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0363898 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.03605 |
| CFAP20DC | CFAP20 domain containing | 0.0346629 |
| GOLGB1 | golgin B1 | 0.0341202 |
| SETD5 | SET domain containing 5 | 0.033881 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0337952 |
| RPL37A | ribosomal protein L37a | 0.0327296 |
| IFI44L | interferon-induced protein 44-like | 0.0325149 |
| RRBP1 | ribosome binding protein 1 | 0.0324251 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0323096 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0320148 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0319578 |
| APOD | apolipoprotein D | 0.0317436 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0311328 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.03101 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0309917 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0301511 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0297176 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0296192 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0288082 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0280931 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0279729 |
| PHF21A | PHD finger protein 21A | 0.0279052 |
| GRID2 | glutamate receptor, ionotropic, delta 2 | 0.0278651 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0275492 |
| VEGFA | vascular endothelial growth factor A | 0.0273993 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0271703 |
| SQSTM1 | sequestosome 1 | 0.0267123 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0256628 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0253021 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0252379 |
| RAD51B | RAD51 paralog B | 0.0251182 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.025074 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0245371 |
| SET | SET nuclear proto-oncogene | 0.0245246 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0240058 |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 | 0.023847 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0236298 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0236082 |
| LEF1 | lymphoid enhancer-binding factor 1 | 0.0234003 |
| RPLP2 | ribosomal protein, large, P2 | 0.023388 |
| MMP12 | matrix metallopeptidase 12 | 0.0233808 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0232514 |
| RPS3 | ribosomal protein S3 | 0.0228464 |
| RPS2 | ribosomal protein S2 | 0.0227631 |
| ATXN1 | ataxin 1 | 0.0226634 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0226532 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0223887 |
| EHBP1 | EH domain binding protein 1 | 0.0222942 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0222875 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0219411 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0218741 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0217341 |
| RPS8 | ribosomal protein S8 | 0.0214306 |
| LAMB1 | laminin, beta 1 | 0.0214258 |
| VMP1 | vacuole membrane protein 1 | 0.0213597 |
| TPM3 | tropomyosin 3 | 0.0213324 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0211136 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0211074 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0210678 |
| CUX1 | cut-like homeobox 1 | 0.020901 |
| ANXA5 | annexin A5 | 0.0208058 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0207418 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0207231 |
| FMNL2 | formin-like 2 | 0.0207019 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0205265 |
| POLR2F | polymerase (RNA) II (DNA directed) polypeptide F | 0.020472 |
| MEF2A | myocyte enhancer factor 2A | 0.0204479 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.272834 |
| FMN1 | formin 1 | -0.175184 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.173444 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0862219 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.077204 |
| FLNA | filamin A, alpha | -0.0656884 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0652511 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0628903 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0611847 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0599188 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0544593 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.054182 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0528142 |
| TXNRD1 | thioredoxin reductase 1 | -0.0518527 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0488588 |
| ANKRD28 | ankyrin repeat domain 28 | -0.046942 |
| ACTG1 | actin gamma 1 | -0.0453723 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0442901 |
| RASAL2 | RAS protein activator like 2 | -0.0434814 |
| ERBIN | erbb2 interacting protein | -0.0432969 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0410085 |
| FRMD5 | FERM domain containing 5 | -0.0402606 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0391671 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -0.0390656 |
| CCND1 | cyclin D1 | -0.0377477 |
| POTEF | POTE ankyrin domain family, member F | -0.034946 |
| PMEL | premelanosome protein | -0.0345892 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0345264 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0337141 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0336289 |
| CLINT1 | clathrin interactor 1 | -0.0333754 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | -0.032297 |
| CA8 | carbonic anhydrase VIII | -0.0322256 |
| ANXA2 | annexin A2 | -0.0316942 |
| TENM1 | teneurin transmembrane protein 1 | -0.0315569 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0299311 |
| TFRC | transferrin receptor | -0.0294718 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0288863 |
| COG5 | component of oligomeric golgi complex 5 | -0.0286628 |
| EXT1 | exostosin glycosyltransferase 1 | -0.028445 |
| KAZN | kazrin, periplakin interacting protein | -0.0283431 |
| TOR1AIP2 | torsin A interacting protein 2 | -0.0282954 |
| SMYD3 | SET and MYND domain containing 3 | -0.0278472 |
| TUBB | tubulin, beta class I | -0.0277957 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0277734 |
| TP63 | tumor protein p63 | -0.0275762 |
| RBM25 | RNA binding motif protein 25 | -0.0271811 |
| COMMD10 | COMM domain containing 10 | -0.0268987 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | -0.026732 |
| CD44 | CD44 molecule (Indian blood group) | -0.0265987 |
| TKT | transketolase | -0.0263689 |
| TCF20 | transcription factor 20 (AR1) | -0.0262423 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0262224 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.026194 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0261469 |
| RLIM | ring finger protein, LIM domain interacting | -0.0259021 |
| FSTL5 | follistatin-like 5 | -0.0257552 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0256415 |
| FILIP1 | filamin A interacting protein 1 | -0.0255801 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0255729 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0248734 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0245691 |
| EPG5 | ectopic P-granules autophagy protein 5 homolog (C. elegans) | -0.0245392 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0243559 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0235545 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0234098 |
| LARP4B | La ribonucleoprotein domain family, member 4B | -0.0229856 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0228535 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | -0.0228532 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0225768 |
| TPTEP2-CSNK1E | TPTEP2-CSNK1E readthrough | -0.0225493 |
| ACTN4 | actinin, alpha 4 | -0.0224303 |
| ACTN1 | actinin, alpha 1 | -0.0224125 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.0223882 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0221233 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0216752 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0214977 |
| GPHN | gephyrin | -0.0214416 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | -0.0212261 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.021053 |
| RTN4 | reticulon 4 | -0.0209172 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0208267 |
| UBC | ubiquitin C | -0.0206422 |
| OXSR1 | oxidative stress responsive 1 | -0.0203013 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0202848 |
| SPAG9 | sperm associated antigen 9 | -0.020273 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.0202288 |
| PCNX4 | pecanex 4 | -0.0202234 |
| COPA | coatomer protein complex, subunit alpha | -0.0202065 |
| NPR2 | natriuretic peptide receptor 2 | -0.0201456 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.0201302 |
| ATP13A3 | ATPase type 13A3 | -0.0201294 |
| NF1 | neurofibromin 1 | -0.0200441 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0200398 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | -0.0200256 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0199991 |
| SLC30A7 | solute carrier family 30 (zinc transporter), member 7 | -0.0197213 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0196808 |
| FNIP1 | folliculin interacting protein 1 | -0.019624 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.019531 |
