| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Azithromycin (hydrate) perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Azithromycin (hydrate)_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0951483 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0743932 |
| RPS12 | ribosomal protein S12 | 0.074228 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0732014 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0547283 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0539559 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0527144 |
| B2M | beta-2-microglobulin | 0.0482082 |
| TXNIP | thioredoxin interacting protein | 0.0474926 |
| ENO1 | enolase 1, (alpha) | 0.0453311 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0450541 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0446249 |
| SQSTM1 | sequestosome 1 | 0.0427677 |
| RNF145 | ring finger protein 145 | 0.0419216 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0396736 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0383661 |
| KIF5B | kinesin family member 5B | 0.0381256 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0379712 |
| AKAP10 | A kinase (PRKA) anchor protein 10 | 0.0373589 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0369746 |
| MT2A | metallothionein 2A | 0.0365084 |
| PGK1 | phosphoglycerate kinase 1 | 0.0354196 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.034935 |
| MXI1 | MAX interactor 1, dimerization protein | 0.034651 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0338251 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0337641 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0325395 |
| PTK2 | protein tyrosine kinase 2 | 0.0325308 |
| RLF | rearranged L-myc fusion | 0.0324066 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0322077 |
| RPS2 | ribosomal protein S2 | 0.0320503 |
| RPS3 | ribosomal protein S3 | 0.0312904 |
| HELZ | helicase with zinc finger | 0.0311475 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0307047 |
| ARL4C | ADP-ribosylation factor-like 4C | 0.0304019 |
| MEF2A | myocyte enhancer factor 2A | 0.0301112 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0299008 |
| RSF1 | remodeling and spacing factor 1 | 0.0293329 |
| LMO7 | LIM domain 7 | 0.0290443 |
| LIMD1 | LIM domains containing 1 | 0.0285076 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0282447 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0282261 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | 0.0281601 |
| DENR | density-regulated protein | 0.0278216 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0277297 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.027144 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0270166 |
| RPS25 | ribosomal protein S25 | 0.0269222 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0268157 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0267909 |
| TMF1 | TATA element modulatory factor 1 | 0.0266084 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0263662 |
| RPL37A | ribosomal protein L37a | 0.0259234 |
| HSPB1 | heat shock 27kDa protein 1 | 0.0258209 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0257917 |
| VIM | vimentin | 0.0256886 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0256503 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0255321 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0255008 |
| CD2AP | CD2-associated protein | 0.0247406 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.024612 |
| RPS10 | ribosomal protein S10 | 0.0243558 |
| TPM4 | tropomyosin 4 | 0.0241672 |
| GOLGA4 | golgin A4 | 0.0239847 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0237164 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0235901 |
| IMMT | inner membrane protein, mitochondrial | 0.0235534 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0234869 |
| FTL | ferritin, light polypeptide | 0.0232827 |
| SET | SET nuclear proto-oncogene | 0.0232021 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0231669 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0230693 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.022914 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0228936 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.022686 |
| RPL7A | ribosomal protein L7a | 0.0225333 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0224321 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.022368 |
| CTBP2 | C-terminal binding protein 2 | 0.0222489 |
| VMP1 | vacuole membrane protein 1 | 0.0219867 |
| USP3 | ubiquitin specific peptidase 3 | 0.0219631 |
| EPB41 | erythrocyte membrane protein band 4.1 | 0.0218255 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.0218252 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0217333 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0215808 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0215347 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0214895 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0213936 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0213446 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0210808 |
| FAM13A | family with sequence similarity 13, member A | 0.0210546 |
| RB1 | retinoblastoma 1 | 0.0210004 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0209923 |
| YEATS2 | YEATS domain containing 2 | 0.0206422 |
| LYPLA1 | lysophospholipase I | 0.0205075 |
| RPS7 | ribosomal protein S7 | 0.0202306 |
| TMOD3 | tropomodulin 3 (ubiquitous) | 0.0202259 |
| BMP2K | BMP2 inducible kinase | 0.02012 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0198442 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | 0.019783 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.173148 |
| PKM | pyruvate kinase, muscle | -0.169277 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.115762 |
| VCL | vinculin | -0.106975 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.106597 |
| EGFR | epidermal growth factor receptor | -0.105241 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0998762 |
| BMP10 | bone morphogenetic protein 10 | -0.0924968 |
| SLC38A2 | solute carrier family 38, member 2 | -0.087857 |
| RPL35A | ribosomal protein L35a | -0.0848529 |
| FLNB | filamin B, beta | -0.0766436 |
| GLI2 | GLI family zinc finger 2 | -0.0725415 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0718024 |
| POTEF | POTE ankyrin domain family, member F | -0.064413 |
| CCND1 | cyclin D1 | -0.0638245 |
| NBEA | neurobeachin | -0.0625547 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0615324 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0612384 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.0603488 |
| TJP1 | tight junction protein 1 | -0.0588392 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0583116 |
| ACTG1 | actin gamma 1 | -0.0562071 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0551566 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0531347 |
| RPLP1 | ribosomal protein, large, P1 | -0.0528638 |
| ECT2 | epithelial cell transforming 2 | -0.0527707 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0512745 |
| SOX6 | SRY (sex determining region Y)-box 6 | -0.0511725 |
| GLI3 | GLI family zinc finger 3 | -0.0510145 |
| AHNAK | AHNAK nucleoprotein | -0.0505602 |
| RPL34 | ribosomal protein L34 | -0.0501592 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0498625 |
| EFNA5 | ephrin-A5 | -0.0487143 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0477358 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0475229 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | -0.0464717 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0456908 |
| NAV2 | neuron navigator 2 | -0.0447395 |
| SFPQ | splicing factor proline/glutamine-rich | -0.0441508 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0440548 |
| RPLP0 | ribosomal protein, large, P0 | -0.0435868 |
| KPNB1 | karyopherin (importin) beta 1 | -0.043174 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0426195 |
| GSE1 | Gse1 coiled-coil protein | -0.0413502 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 | -0.0399613 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0394746 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0394478 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | -0.039443 |
| HJURP | Holliday junction recognition protein | -0.0383849 |
| PTMS | parathymosin | -0.0378136 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0365469 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0364495 |
| CENPF | centromere protein F, 350/400kDa | -0.0361344 |
| ZNF438 | zinc finger protein 438 | -0.0354605 |
| PHF14 | PHD finger protein 14 | -0.0350793 |
| ZNF644 | zinc finger protein 644 | -0.0348552 |
| YAP1 | Yes-associated protein 1 | -0.0339305 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0329383 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.032209 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0321192 |
| TPX2 | TPX2, microtubule-associated | -0.0320719 |
| ZNF217 | zinc finger protein 217 | -0.0318777 |
| EPC2 | enhancer of polycomb homolog 2 (Drosophila) | -0.0317209 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0316663 |
| NF1 | neurofibromin 1 | -0.031501 |
| FBLN2 | fibulin 2 | -0.0311216 |
| S100A4 | S100 calcium binding protein A4 | -0.0307619 |
| EBNA1BP2 | EBNA1 binding protein 2 | -0.0305762 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.030452 |
| CD47 | CD47 molecule | -0.0303543 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0303394 |
| ZZZ3 | zinc finger, ZZ-type containing 3 | -0.0303373 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0303299 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0296346 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0295406 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0295067 |
| RPL3 | ribosomal protein L3 | -0.0294298 |
| PLXNA1 | plexin A1 | -0.0293142 |
| TAPBP | TAP binding protein (tapasin) | -0.0292604 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0290305 |
| CREBBP | CREB binding protein | -0.0288935 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0288095 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0285189 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0282227 |
| TMEM65 | transmembrane protein 65 | -0.0277773 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0274822 |
| ZNF608 | zinc finger protein 608 | -0.0272868 |
| SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 | -0.0272784 |
| METTL15 | methyltransferase like 15 | -0.0271336 |
| CRPPA | CDP-L-ribitol pyrophosphorylase A | -0.02703 |
| HMGA1 | high mobility group AT-hook 1 | -0.0269803 |
| CDYL | chromodomain protein, Y-like | -0.0268223 |
| ERCC6L2 | excision repair cross-complementation group 6-like 2 | -0.0267857 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0265491 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0264911 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | -0.0264115 |
| ARHGAP25 | Rho GTPase activating protein 25 | -0.0264034 |
| PFN1 | profilin 1 | -0.0260138 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.0259327 |
| IRS1 | insulin receptor substrate 1 | -0.0258601 |
