| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Azithromycin (hydrate) perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Azithromycin (hydrate)_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.149402 |
| STC1 | stanniocalcin 1 | 0.10201 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.100877 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0821327 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0760524 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.071872 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0697772 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0671302 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0626704 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0591692 |
| ZNF292 | zinc finger protein 292 | 0.0558788 |
| RPS12 | ribosomal protein S12 | 0.0554017 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0549022 |
| MT2A | metallothionein 2A | 0.0525098 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0522472 |
| IER3 | immediate early response 3 | 0.0515147 |
| SQSTM1 | sequestosome 1 | 0.0510658 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0491667 |
| TXNIP | thioredoxin interacting protein | 0.0485653 |
| B2M | beta-2-microglobulin | 0.0477915 |
| OGA | O-GlcNAcase | 0.0474588 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0469386 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0447117 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0441779 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0436904 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.0418964 |
| PRELID2 | PRELI domain containing 2 | 0.0415187 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 0.0398904 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0388755 |
| JMJD1C | jumonji domain containing 1C | 0.0377003 |
| ENO1 | enolase 1, (alpha) | 0.0376784 |
| RPS8 | ribosomal protein S8 | 0.0373429 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0369637 |
| RPS2 | ribosomal protein S2 | 0.0364603 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.03509 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0348914 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.033914 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0336463 |
| PGK1 | phosphoglycerate kinase 1 | 0.0334944 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0334522 |
| MSN | moesin | 0.0330227 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0328367 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0326994 |
| ASPH | aspartate beta-hydroxylase | 0.0325828 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0324172 |
| VMP1 | vacuole membrane protein 1 | 0.0322091 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0304933 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0304468 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0303939 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0300262 |
| VCAN | versican | 0.0299241 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0296327 |
| KIF13A | kinesin family member 13A | 0.0290669 |
| RPL11 | ribosomal protein L11 | 0.028677 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0284474 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | 0.028283 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0282362 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0280006 |
| WDFY1 | WD repeat and FYVE domain containing 1 | 0.0277518 |
| FMNL2 | formin-like 2 | 0.0277224 |
| PHF21A | PHD finger protein 21A | 0.0276346 |
| WDR26 | WD repeat domain 26 | 0.0268854 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0268089 |
| DUSP10 | dual specificity phosphatase 10 | 0.0264065 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0261574 |
| FOXO3 | forkhead box O3 | 0.0260035 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0258148 |
| UBE2B | ubiquitin-conjugating enzyme E2B | 0.025786 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0252669 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0251777 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0251056 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0250761 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0249343 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0247908 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0247799 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0245201 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0244484 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0244089 |
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 | 0.0243862 |
| FAM13A | family with sequence similarity 13, member A | 0.0241897 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0240055 |
| SYNJ2 | synaptojanin 2 | 0.0236785 |
| RPS3 | ribosomal protein S3 | 0.0235507 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0235247 |
| ARFGEF3 | ARFGEF family member 3 | 0.0235081 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0231545 |
| IGF2R | insulin-like growth factor 2 receptor | 0.0228894 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0227556 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.022545 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0224146 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0222624 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.022059 |
| ANXA2 | annexin A2 | 0.0220481 |
| CEP250 | centrosomal protein 250kDa | 0.0219807 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0216459 |
| ADM | adrenomedullin | 0.0215142 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0213466 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0213064 |
| ARRDC3 | arrestin domain containing 3 | 0.0212909 |
| YBX3 | Y box binding protein 3 | 0.0212079 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SOD2 | superoxide dismutase 2, mitochondrial | -0.298806 |
| FN1 | fibronectin 1 | -0.215258 |
| VIM | vimentin | -0.142532 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.128139 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0797735 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0785709 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0716768 |
| CADM1 | cell adhesion molecule 1 | -0.0604478 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0571011 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0554687 |
| TMSB10 | thymosin beta 10 | -0.0512033 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0504285 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0495744 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0478437 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.047149 |
| VCL | vinculin | -0.0470028 |
| FRMD4A | FERM domain containing 4A | -0.0442025 |
| EGR1 | early growth response 1 | -0.0441423 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0441181 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0438434 |
| PDE10A | phosphodiesterase 10A | -0.043434 |
| THBS1 | thrombospondin 1 | -0.0433417 |
| CLIC4 | chloride intracellular channel 4 | -0.0429724 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0423812 |
| TAPBP | TAP binding protein (tapasin) | -0.0402086 |
| CTSD | cathepsin D | -0.0398669 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.038085 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0375386 |
| DST | dystonin | -0.0366804 |
| TNS3 | tensin 3 | -0.0364 |
| DIAPH2 | diaphanous-related formin 2 | -0.0362894 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.036028 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0355398 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0346537 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0343569 |
| RNF213 | ring finger protein 213 | -0.0330946 |
| NABP1 | nucleic acid binding protein 1 | -0.0328768 |
| PALLD | palladin, cytoskeletal associated protein | -0.0328398 |
| TXNRD1 | thioredoxin reductase 1 | -0.0327935 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0327392 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0321899 |
| RAI14 | retinoic acid induced 14 | -0.031788 |
| FLNB | filamin B, beta | -0.0313085 |
| TMSB4X | thymosin beta 4, X-linked | -0.0313042 |
| PARD3 | par-3 family cell polarity regulator | -0.0311502 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0309623 |
| ACTG1 | actin gamma 1 | -0.0308787 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0304955 |
| TMEM123 | transmembrane protein 123 | -0.0300986 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.028443 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0281841 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.028139 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0277938 |
| MORF4L2 | mortality factor 4 like 2 | -0.0277742 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.0277361 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0271639 |
| SFTPA2 | surfactant protein A2 | -0.0271191 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0269528 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.026951 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0267388 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0264321 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0262913 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0262556 |
| FLNA | filamin A, alpha | -0.0261585 |
| TUBB | tubulin, beta class I | -0.0260548 |
| TKT | transketolase | -0.0258694 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0251755 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0251205 |
| BICC1 | BicC family RNA binding protein 1 | -0.0248372 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0246768 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0246521 |
| DNER | delta/notch-like EGF repeat containing | -0.0245228 |
| HMGA1 | high mobility group AT-hook 1 | -0.0244166 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0243144 |
| LOX | lysyl oxidase | -0.0240602 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0237808 |
| FRMPD4 | FERM and PDZ domain containing 4 | -0.0234528 |
| RPS24 | ribosomal protein S24 | -0.0233749 |
| RPL35A | ribosomal protein L35a | -0.0232303 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0231499 |
| KLHL5 | kelch-like family member 5 | -0.023065 |
| SGMS1 | sphingomyelin synthase 1 | -0.0228115 |
| PRR16 | proline rich 16 | -0.0228019 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0226161 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | -0.02258 |
| CLTC | clathrin, heavy chain (Hc) | -0.0222276 |
| HLA-A | major histocompatibility complex, class I, A | -0.0220321 |
| TPM1 | tropomyosin 1 (alpha) | -0.0216947 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.0214144 |
| CFB | complement factor B | -0.0211877 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0208761 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0208527 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0207244 |
| RPL3 | ribosomal protein L3 | -0.0207226 |
| HMGA2 | high mobility group AT-hook 2 | -0.0203818 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0202685 |
| SRSF3 | serine/arginine-rich splicing factor 3 | -0.0200964 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0198252 |
| WASF2 | WAS protein family, member 2 | -0.0196514 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0195593 |
