| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Azithromycin (hydrate) perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Azithromycin (hydrate)_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.101194 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0909166 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0902361 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0671607 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0589538 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0540434 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0501109 |
| PDLIM5 | PDZ and LIM domain 5 | 0.042433 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0393053 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0386548 |
| TXNIP | thioredoxin interacting protein | 0.0374133 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0365864 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0362524 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0353845 |
| RPS12 | ribosomal protein S12 | 0.0332183 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0326739 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0279088 |
| INTS6 | integrator complex subunit 6 | 0.027271 |
| SON | SON DNA binding protein | 0.0272533 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0272247 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0263484 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0261688 |
| STC1 | stanniocalcin 1 | 0.0260834 |
| JMJD1C | jumonji domain containing 1C | 0.0254164 |
| FHL2 | four and a half LIM domains 2 | 0.0251677 |
| PLIN2 | perilipin 2 | 0.0249871 |
| ANGPTL4 | angiopoietin-like 4 | 0.0247994 |
| SVIL | supervillin | 0.0245019 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.024102 |
| VMP1 | vacuole membrane protein 1 | 0.0238105 |
| AREG | amphiregulin | 0.0236648 |
| FLNB | filamin B, beta | 0.0231687 |
| RPS2 | ribosomal protein S2 | 0.0226165 |
| EGFR | epidermal growth factor receptor | 0.0225518 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0211272 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0210078 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0209934 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0208623 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | 0.020855 |
| OXR1 | oxidation resistance 1 | 0.0207954 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0204769 |
| GOLGA4 | golgin A4 | 0.0204213 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0203976 |
| ZC3H12C | zinc finger CCCH-type containing 12C | 0.0200412 |
| ERBIN | erbb2 interacting protein | 0.0198928 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0198798 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0196839 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0192243 |
| HSPA1A | heat shock 70kDa protein 1A | 0.0190122 |
| RAB10 | RAB10, member RAS oncogene family | 0.0189663 |
| RBPMS | RNA binding protein with multiple splicing | 0.018945 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0189344 |
| RND3 | Rho family GTPase 3 | 0.0188717 |
| HDAC9 | histone deacetylase 9 | 0.0188332 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0186748 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0186297 |
| GOLM2 | golgi membrane protein 2 | 0.0185803 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0185734 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0185572 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0185005 |
| PHF3 | PHD finger protein 3 | 0.0184695 |
| MT2A | metallothionein 2A | 0.0183247 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0181855 |
| ATXN1 | ataxin 1 | 0.0180869 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0180857 |
| DDX24 | DEAD (Asp-Glu-Ala-Asp) box helicase 24 | 0.0180809 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.018016 |
| CTBP2 | C-terminal binding protein 2 | 0.0178642 |
| PRKCE | protein kinase C, epsilon | 0.0178143 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0178002 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0177823 |
| VPS53 | vacuolar protein sorting 53 homolog (S. cerevisiae) | 0.0174931 |
| PDE10A | phosphodiesterase 10A | 0.0174518 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0174077 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0173936 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.017332 |
| XRRA1 | X-ray radiation resistance associated 1 | 0.0172664 |
| UTRN | utrophin | 0.0171898 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0171629 |
| DSTN | destrin (actin depolymerizing factor) | 0.0170719 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0169288 |
| NEBL | nebulette | 0.0167832 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0167678 |
| BPTF | bromodomain PHD finger transcription factor | 0.0167312 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | 0.0166859 |
| LOXL2 | lysyl oxidase-like 2 | 0.0164141 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.016145 |
| RPL21 | ribosomal protein L21 | 0.0159333 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0159192 |
| DYNC1I2 | dynein, cytoplasmic 1, intermediate chain 2 | 0.0157694 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0157582 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0157353 |
| LYST | lysosomal trafficking regulator | 0.0157105 |
| MSN | moesin | 0.015494 |
| FTL | ferritin, light polypeptide | 0.0154811 |
| AFDN | afadin, adherens junction formation factor | 0.015416 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.015414 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0153492 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0152324 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0151278 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.291519 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.288092 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.259659 |
| PTMA | prothymosin, alpha | -0.127184 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.11366 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.111436 |
| TMSB4X | thymosin beta 4, X-linked | -0.108342 |
| NRG1 | neuregulin 1 | -0.0962992 |
| HLA-B | major histocompatibility complex, class I, B | -0.0957003 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0862306 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0825634 |
| S100A6 | S100 calcium binding protein A6 | -0.0807666 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0794898 |
| TMSB10 | thymosin beta 10 | -0.0700509 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0690431 |
| SFTPA2 | surfactant protein A2 | -0.0680658 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0679763 |
| CANX | calnexin | -0.0677949 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0589882 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0585628 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0575403 |
| LMNA | lamin A/C | -0.0557464 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0540524 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0540472 |
| PGK1 | phosphoglycerate kinase 1 | -0.0526602 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0523781 |
| MKI67 | marker of proliferation Ki-67 | -0.0519808 |
| GLIS3 | GLIS family zinc finger 3 | -0.0519742 |
| SPAG9 | sperm associated antigen 9 | -0.0509471 |
| CENPF | centromere protein F, 350/400kDa | -0.0497411 |
| KLHL5 | kelch-like family member 5 | -0.0493847 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0468843 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0452334 |
| COPA | coatomer protein complex, subunit alpha | -0.0449716 |
| CADM1 | cell adhesion molecule 1 | -0.0448404 |
| PKM | pyruvate kinase, muscle | -0.0442511 |
| LOC112694756 | uncharaterized LOC112694756 | -0.042964 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0428627 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0427718 |
| AEBP2 | AE binding protein 2 | -0.0422547 |
| ITGA1 | integrin, alpha 1 | -0.042086 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0415692 |
| CALU | calumenin | -0.0412569 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0404659 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0397309 |
| SYT1 | synaptotagmin I | -0.0396726 |
| H1-0 | H1.0 linker histone | -0.0391117 |
| EGR1 | early growth response 1 | -0.0390549 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.038931 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0382744 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0381322 |
| TMEM156 | transmembrane protein 156 | -0.0380531 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0376881 |
| RPL35A | ribosomal protein L35a | -0.0374919 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0370703 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0370595 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0364762 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0359502 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0357614 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0356659 |
| WDR45B | WD repeat domain 45B | -0.0354626 |
| ETNK1 | ethanolamine kinase 1 | -0.0351136 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.035088 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0348821 |
| GNAS | GNAS complex locus | -0.0348361 |
| IER3 | immediate early response 3 | -0.0347523 |
| SQSTM1 | sequestosome 1 | -0.0345147 |
| WAC | WW domain containing adaptor with coiled-coil | -0.034335 |
| RUNX2 | runt-related transcription factor 2 | -0.0334796 |
| VIM | vimentin | -0.0333332 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0332985 |
| ARF1 | ADP-ribosylation factor 1 | -0.0328846 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0328662 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0327054 |
| RPL34 | ribosomal protein L34 | -0.0327044 |
| ETV6 | ets variant 6 | -0.0325103 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0320774 |
| SDCBP | syndecan binding protein (syntenin) | -0.0319219 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.031126 |
| HMGB3 | high mobility group box 3 | -0.0310044 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0305223 |
| TPR | translocated promoter region, nuclear basket protein | -0.0305169 |
| HPCAL1 | hippocalcin-like 1 | -0.0302936 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0301904 |
| MAP1B | microtubule-associated protein 1B | -0.0301764 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0300424 |
| TAGLN2 | transgelin 2 | -0.0299564 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0296394 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0296248 |
| RPS20 | ribosomal protein S20 | -0.0291353 |
| CDC73 | cell division cycle 73 | -0.0290881 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | -0.0290017 |
| CLINT1 | clathrin interactor 1 | -0.0289893 |
| ETV1 | ets variant 1 | -0.0288063 |
| TENM4 | teneurin transmembrane protein 4 | -0.0287687 |
| STC2 | stanniocalcin 2 | -0.0283317 |
| SEPTIN7 | septin 7 | -0.0281044 |
| SSH1 | slingshot protein phosphatase 1 | -0.0280844 |
| RNF145 | ring finger protein 145 | -0.0277549 |
| DENND5B | DENN/MADD domain containing 5B | -0.0276455 |