| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Azithromycin (hydrate) perturbation in SW48 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Azithromycin (hydrate)_SW48 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AREG | amphiregulin | 0.103687 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.087617 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0683602 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0610244 |
| RPS12 | ribosomal protein S12 | 0.0521957 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0503624 |
| RPS6 | ribosomal protein S6 | 0.0485164 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0428591 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0403861 |
| CPOX | coproporphyrinogen oxidase | 0.0403068 |
| ATXN1 | ataxin 1 | 0.039971 |
| GOLGA4 | golgin A4 | 0.0396969 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0392145 |
| TXNIP | thioredoxin interacting protein | 0.039107 |
| EZR | ezrin | 0.036583 |
| RPS2 | ribosomal protein S2 | 0.0358445 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0357282 |
| YAP1 | Yes-associated protein 1 | 0.0346737 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0338942 |
| FN1 | fibronectin 1 | 0.0331819 |
| KIF5B | kinesin family member 5B | 0.033123 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0323456 |
| H1-2 | H1.2 linker histone, cluster member | 0.0319566 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0313044 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | 0.0307896 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0303887 |
| VMP1 | vacuole membrane protein 1 | 0.0298861 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0298316 |
| SNX9 | sorting nexin 9 | 0.0297141 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.029607 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0275674 |
| MPP2 | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) | 0.0273949 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0273382 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0273219 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0271262 |
| EFNB2 | ephrin-B2 | 0.0266813 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0256114 |
| PNN | pinin, desmosome associated protein | 0.0255081 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0252269 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0245005 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0234854 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0232721 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0232498 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0231173 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0225851 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0224873 |
| LUC7L | LUC7-like (S. cerevisiae) | 0.0222824 |
| SYAP1 | synapse associated protein 1 | 0.0220956 |
| ASPH | aspartate beta-hydroxylase | 0.0219621 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0218678 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0217892 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0216838 |
| SEPTIN7 | septin 7 | 0.0216453 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0212494 |
| CENPF | centromere protein F, 350/400kDa | 0.0211734 |
| AXIN2 | axin 2 | 0.0208996 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0208842 |
| RPL21 | ribosomal protein L21 | 0.0208724 |
| SEPTIN9 | septin 9 | 0.0208263 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0207367 |
| DST | dystonin | 0.0206942 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0206828 |
| ZFP36 | ZFP36 ring finger protein | 0.0205701 |
| DSPP | dentin sialophosphoprotein | 0.0204661 |
| H1-4 | H1.4 linker histone, cluster member | 0.0204188 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0203735 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0203567 |
| FBXO11 | F-box protein 11 | 0.0202854 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0201013 |
| ARRDC3 | arrestin domain containing 3 | 0.0198311 |
| TPR | translocated promoter region, nuclear basket protein | 0.019714 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0194998 |
| CEP350 | centrosomal protein 350kDa | 0.0194761 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0193502 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0191676 |
| TMEM41B | transmembrane protein 41B | 0.0191492 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0191454 |
| ENO1 | enolase 1, (alpha) | 0.0189534 |
| ZNF292 | zinc finger protein 292 | 0.0188757 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0188468 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0186805 |
| CHD4 | chromodomain helicase DNA binding protein 4 | 0.0185754 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0185588 |
| NUP58 | nucleoporin 58 | 0.0185269 |
| SNX6 | sorting nexin 6 | 0.0184998 |
| DENR | density-regulated protein | 0.0184299 |
| XPO1 | exportin 1 | 0.0182823 |
| USP6NL | USP6 N-terminal like | 0.0182552 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0182168 |
| RNF43 | ring finger protein 43 | 0.0181905 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0180845 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0180072 |
| MAN1A2 | mannosidase, alpha, class 1A, member 2 | 0.0179715 |
| SRSF4 | serine/arginine-rich splicing factor 4 | 0.0177819 |
| CLDND1 | claudin domain containing 1 | 0.0177584 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0177317 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0176929 |
| SUPT16H | suppressor of Ty 16 homolog (S. cerevisiae) | 0.0176124 |
| JMJD1C | jumonji domain containing 1C | 0.0176071 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0172268 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.298199 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 | -0.129361 |
| FHIT | fragile histidine triad | -0.0956087 |
| RAD51B | RAD51 paralog B | -0.0946287 |
| VCL | vinculin | -0.0924422 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0854677 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0782664 |
| TMSB10 | thymosin beta 10 | -0.0736859 |
| PTMA | prothymosin, alpha | -0.0725874 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0725604 |
| RPS24 | ribosomal protein S24 | -0.0673536 |
| FLOT1 | flotillin 1 | -0.0649525 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0646859 |
| ANXA2 | annexin A2 | -0.0602683 |
| HDAC2 | histone deacetylase 2 | -0.0583834 |
| ACTG1 | actin gamma 1 | -0.0577117 |
| LAMB3 | laminin, beta 3 | -0.057179 |
| RPL35A | ribosomal protein L35a | -0.0561161 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.052288 |
| LMO7 | LIM domain 7 | -0.0516276 |
| EGR1 | early growth response 1 | -0.0510321 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0496796 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0489691 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0463571 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0444708 |
| RUNX2 | runt-related transcription factor 2 | -0.0442254 |
| MTAP | methylthioadenosine phosphorylase | -0.0440227 |
| ACTN4 | actinin, alpha 4 | -0.0423548 |
| LDHA | lactate dehydrogenase A | -0.0423481 |
| DENND1A | DENN/MADD domain containing 1A | -0.0417385 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0413894 |
| LRP8 | low density lipoprotein receptor-related protein 8, apolipoprotein e receptor | -0.040124 |
| COG5 | component of oligomeric golgi complex 5 | -0.0397096 |
| TRAF3 | TNF receptor-associated factor 3 | -0.0388454 |
| ZBTB7C | zinc finger and BTB domain containing 7C | -0.0363103 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.036106 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0354788 |
| GPHN | gephyrin | -0.0352796 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0345203 |
| CUX1 | cut-like homeobox 1 | -0.0338362 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0332162 |
| FERMT1 | fermitin family member 1 | -0.0328918 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0328905 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0325888 |
| RCOR1 | REST corepressor 1 | -0.032342 |
| GPC5 | glypican 5 | -0.0304706 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0303638 |
| RPL13A | ribosomal protein L13a | -0.0295743 |
| NFIA | nuclear factor I/A | -0.0293962 |
| AOPEP | aminopeptidase O (putative) | -0.0290635 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | -0.0287793 |
| RPL4 | ribosomal protein L4 | -0.0287229 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0286462 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0281814 |
| CMIP | c-Maf inducing protein | -0.0276652 |
| EXOC4 | exocyst complex component 4 | -0.0275507 |
| SERINC5 | serine incorporator 5 | -0.0275275 |
| PDLIM5 | PDZ and LIM domain 5 | -0.027459 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | -0.0269321 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0267971 |
| TNS3 | tensin 3 | -0.0266786 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0265958 |
| KRT18 | keratin 18, type I | -0.026493 |
| RREB1 | ras responsive element binding protein 1 | -0.0264922 |
| ANXA11 | annexin A11 | -0.0259332 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0257212 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | -0.0254333 |
| PSPC1 | paraspeckle component 1 | -0.0250947 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0250768 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.02491 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0247833 |
| CD9 | CD9 molecule | -0.0247422 |
| ANXA3 | annexin A3 | -0.0244726 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0244542 |
| SMYD3 | SET and MYND domain containing 3 | -0.0244101 |
| RPL34 | ribosomal protein L34 | -0.0242213 |
| RPL9 | ribosomal protein L9 | -0.0238806 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0234329 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0234206 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | -0.0233382 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0229089 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0227183 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0227172 |
| CCND1 | cyclin D1 | -0.0224244 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0224175 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0220563 |
| PRRC2B | proline-rich coiled-coil 2B | -0.021945 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0218395 |
| ANLN | anillin, actin binding protein | -0.0214009 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0212933 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0212865 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0210703 |
| RPL12 | ribosomal protein L12 | -0.021068 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | -0.0210358 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0209652 |
| ADGRA3 | adhesion G protein-coupled receptor A3 | -0.0208564 |
| KRT8 | keratin 8, type II | -0.0208271 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.020741 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0206641 |
| SCFD1 | sec1 family domain containing 1 | -0.0206623 |