| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Azithromycin (hydrate) perturbation in hTERT-HPNE cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Azithromycin (hydrate)_hTERT-HPNE drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.359011 |
| MYO10 | myosin X | 0.121158 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.116239 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.106855 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0988488 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0894802 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0769105 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0700479 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0654991 |
| CD44 | CD44 molecule (Indian blood group) | 0.0631079 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0627296 |
| STC1 | stanniocalcin 1 | 0.0603778 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0574177 |
| RPS6 | ribosomal protein S6 | 0.0557819 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0552429 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0517181 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0507806 |
| VEGFA | vascular endothelial growth factor A | 0.0498258 |
| PRRC2C | proline-rich coiled-coil 2C | 0.047334 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0470422 |
| MSN | moesin | 0.0450348 |
| SMAD3 | SMAD family member 3 | 0.0440095 |
| VMP1 | vacuole membrane protein 1 | 0.0432351 |
| RUNX1 | runt-related transcription factor 1 | 0.0424976 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0418095 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0415428 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0412069 |
| EGFR | epidermal growth factor receptor | 0.041167 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0402846 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0402779 |
| FAM13A | family with sequence similarity 13, member A | 0.0400081 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0399022 |
| ASPH | aspartate beta-hydroxylase | 0.0394157 |
| RPS8 | ribosomal protein S8 | 0.0393254 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0392271 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0388025 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0385134 |
| DSPP | dentin sialophosphoprotein | 0.0382148 |
| COL5A3 | collagen, type V, alpha 3 | 0.0381045 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0361241 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.035642 |
| SPAG9 | sperm associated antigen 9 | 0.0354311 |
| CLMP | CXADR-like membrane protein | 0.0353494 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0347234 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0346597 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0340737 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0335618 |
| SNX9 | sorting nexin 9 | 0.0333181 |
| RASA2 | RAS p21 protein activator 2 | 0.0332067 |
| ANXA5 | annexin A5 | 0.0329106 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0326885 |
| TOP1 | topoisomerase (DNA) I | 0.0326455 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0322062 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0317905 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0316815 |
| RNF145 | ring finger protein 145 | 0.0316475 |
| RPS12 | ribosomal protein S12 | 0.0312138 |
| BPTF | bromodomain PHD finger transcription factor | 0.0306508 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0305289 |
| ARHGAP31 | Rho GTPase activating protein 31 | 0.0304906 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0299213 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0291965 |
| SETD5 | SET domain containing 5 | 0.0291699 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0291154 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0290299 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.028103 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0275199 |
| MT2A | metallothionein 2A | 0.027387 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0272854 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0271209 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0268218 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0263459 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | 0.0263075 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0261175 |
| TXNIP | thioredoxin interacting protein | 0.0259928 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0255908 |
| RPL23 | ribosomal protein L23 | 0.025528 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.02551 |
| ZNF638 | zinc finger protein 638 | 0.0254617 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0251297 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0246969 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.024632 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0243768 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0241837 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0239221 |
| ANKRD11 | ankyrin repeat domain 11 | 0.023632 |
| SET | SET nuclear proto-oncogene | 0.0235687 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0232198 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0227912 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0226902 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0226224 |
| GPHN | gephyrin | 0.0226069 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0225968 |
| BRD2 | bromodomain containing 2 | 0.022474 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0223856 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0220366 |
| HBEGF | heparin-binding EGF-like growth factor | 0.0219865 |
| IL6 | interleukin 6 | 0.021947 |
| FBXO11 | F-box protein 11 | 0.0218301 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0214496 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | -0.300173 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.230878 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.176563 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.16321 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.131217 |
| MMP1 | matrix metallopeptidase 1 | -0.122794 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.120556 |
| COL6A2 | collagen, type VI, alpha 2 | -0.103761 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 | -0.0983348 |
| OXR1 | oxidation resistance 1 | -0.0776359 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0749769 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0744056 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0636004 |
| TMSB10 | thymosin beta 10 | -0.0623474 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0607337 |
| CDH13 | cadherin 13 | -0.0603822 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0575465 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0552764 |
| NCKAP5 | NCK-associated protein 5 | -0.0503648 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0489801 |
| FBN1 | fibrillin 1 | -0.0486646 |
| COL1A1 | collagen, type I, alpha 1 | -0.0475238 |
| COL5A1 | collagen, type V, alpha 1 | -0.0457364 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.044692 |
| CALR | calreticulin | -0.0415488 |
| HLA-B | major histocompatibility complex, class I, B | -0.0406712 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | -0.0399556 |
| FRMPD4 | FERM and PDZ domain containing 4 | -0.038139 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.036946 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0364094 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0352258 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0342034 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0341736 |
| PRRX1 | paired related homeobox 1 | -0.0336881 |
| NREP | neuronal regeneration related protein | -0.0331628 |
| HDLBP | high density lipoprotein binding protein | -0.032152 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0315643 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0315036 |
| AHNAK | AHNAK nucleoprotein | -0.031103 |
| DGKI | diacylglycerol kinase, iota | -0.0309213 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0303572 |
| PRSS23 | protease, serine, 23 | -0.0296486 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.02915 |
| TTC23L | tetratricopeptide repeat domain 23-like | -0.0286051 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0274099 |
| S100A6 | S100 calcium binding protein A6 | -0.026302 |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 | -0.0260207 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0259165 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0255644 |
| GLIS3 | GLIS family zinc finger 3 | -0.0246539 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.0242198 |
| DIAPH2 | diaphanous-related formin 2 | -0.0240538 |
| TRPC4 | transient receptor potential cation channel, subfamily C, member 4 | -0.0237836 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0234797 |
| HLA-C | major histocompatibility complex, class I, C | -0.0232878 |
| KIAA1549L | KIAA1549-like | -0.0228958 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0224793 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0223473 |
| COL3A1 | collagen, type III, alpha 1 | -0.0221264 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0219659 |
| TPM4 | tropomyosin 4 | -0.0215653 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0213306 |
| EBF1 | early B-cell factor 1 | -0.0211519 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0208864 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | -0.0205538 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.02055 |
| FSTL1 | follistatin-like 1 | -0.020518 |
| PGK1 | phosphoglycerate kinase 1 | -0.0204122 |
| DPYD | dihydropyrimidine dehydrogenase | -0.020348 |
| MMP12 | matrix metallopeptidase 12 | -0.0203341 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0202156 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0201969 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | -0.0199249 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0198779 |
| COL12A1 | collagen, type XII, alpha 1 | -0.0197631 |
| RPS24 | ribosomal protein S24 | -0.019641 |
| IGF2 | insulin-like growth factor 2 | -0.0194832 |
| COL1A2 | collagen, type I, alpha 2 | -0.0194398 |
| RNF213 | ring finger protein 213 | -0.0193139 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0192529 |
| BNC2 | basonuclin 2 | -0.0190788 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0189919 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0189083 |
| RUNX2 | runt-related transcription factor 2 | -0.0185117 |
| PRR16 | proline rich 16 | -0.0184445 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0183554 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0182161 |
| SUGCT | succinyl-CoA:glutarate-CoA transferase | -0.0181242 |
| AEBP2 | AE binding protein 2 | -0.0180924 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.017988 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0179866 |
| PDE7B | phosphodiesterase 7B | -0.017822 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0177974 |
| SLC1A2 | solute carrier family 1 (glial high affinity glutamate transporter), member 2 | -0.0177466 |
| VEPH1 | ventricular zone expressed PH domain-containing 1 | -0.0177072 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0176863 |
| FTL | ferritin, light polypeptide | -0.0173137 |
| CRADD | CASP2 and RIPK1 domain containing adaptor with death domain | -0.0171743 |
| SAR1A | secretion associated, Ras related GTPase 1A | -0.0171517 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | -0.0170559 |
