Azoospermia Gene Set

Dataset DISEASES Experimental Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
Description A condition of suboptimal concentration of SPERMATOZOA in the ejaculated SEMEN to ensure successful FERTILIZATION of an OVUM. In humans, oligospermia is defined as a sperm count below 20 million per milliliter semen. (Experimental Factor Ontology, EFO_0000279)
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Genes

10 genes associated with the disease Azoospermia in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
MORN1 MORN repeat containing 1 1.531
RER1 retention in endoplasmic reticulum sorting receptor 1 1.531
TNFRSF14 tumor necrosis factor receptor superfamily, member 14 1.531
HES5 hes family bHLH transcription factor 5 1.531
PEX10 peroxisomal biogenesis factor 10 1.531
PLCH2 phospholipase C, eta 2 1.531
PANK4 pantothenate kinase 4 1.531
SOX5 SRY (sex determining region Y)-box 5 1.27
SIRPA signal-regulatory protein alpha 0.601
SIRPG signal-regulatory protein gamma 0.601