Azotemia Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description An increased concentration of nitrogen compounds in the blood. (Human Phenotype Ontology, HP_0002157)
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D053099
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Genes

728 genes/proteins associated with the disease Azotemia from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
REN renin 2.88009
GH1 growth hormone 1 2.88009
TNF tumor necrosis factor 2.2745
VEGFA vascular endothelial growth factor A 2.13984
SLC22A7 solute carrier family 22 (organic anion transporter), member 7 2.11104
BCL2 B-cell CLL/lymphoma 2 2.11033
IL6 interleukin 6 2.10486
ALB albumin 2.08633
CCL2 chemokine (C-C motif) ligand 2 2.08272
HMOX1 heme oxygenase 1 2.07866
IL1B interleukin 1, beta 2.04905
SOD2 superoxide dismutase 2, mitochondrial 2.03846
CASP3 caspase 3, apoptosis-related cysteine peptidase 2.03091
DDIT3 DNA-damage-inducible transcript 3 2.02892
CAT catalase 2.02892
TGFB1 transforming growth factor, beta 1 2.0232
BAX BCL2-associated X protein 2.01979
IFNG interferon, gamma 2.012
EDN1 endothelin 1 1.98439
SLC22A6 solute carrier family 22 (organic anion transporter), member 6 1.97596
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.96314
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.95148
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.94062
FOS FBJ murine osteosarcoma viral oncogene homolog 1.93705
MPO myeloperoxidase 1.91716
NOS2 nitric oxide synthase 2, inducible 1.91586
BCL2L1 BCL2-like 1 1.91051
HSPA8 heat shock 70kDa protein 8 1.90542
SLC22A8 solute carrier family 22 (organic anion transporter), member 8 1.90242
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.89601
NOS3 nitric oxide synthase 3 (endothelial cell) 1.89423
ICAM1 intercellular adhesion molecule 1 1.89311
NPPA natriuretic peptide A 1.88917
TP53 tumor protein p53 1.87344
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.86907
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.86045
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.8601
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.83841
IL10 interleukin 10 1.83717
VCAM1 vascular cell adhesion molecule 1 1.82569
F3 coagulation factor III (thromboplastin, tissue factor) 1.82254
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.81848
JUN jun proto-oncogene 1.81629
FASLG Fas ligand (TNF superfamily, member 6) 1.81036
EGR1 early growth response 1 1.79866
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.78682
SPP1 secreted phosphoprotein 1 1.78549
TIMP1 TIMP metallopeptidase inhibitor 1 1.78454
CXCL10 chemokine (C-X-C motif) ligand 10 1.77917
THBS1 thrombospondin 1 1.77801
HSPD1 heat shock 60kDa protein 1 (chaperonin) 1.76946
PPARA peroxisome proliferator-activated receptor alpha 1.76694
GSTP1 glutathione S-transferase pi 1 1.76675
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 1.74882
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 1.74501
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 1.73577
FAS Fas cell surface death receptor 1.71973
IL1A interleukin 1, alpha 1.71627
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 1.70968
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 1.70574
IGF1 insulin-like growth factor 1 (somatomedin C) 1.6993
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 1.69597
AQP2 aquaporin 2 (collecting duct) 1.69318
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.68889
GADD45A growth arrest and DNA-damage-inducible, alpha 1.68868
EPO erythropoietin 1.68591
IL4 interleukin 4 1.67441
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 1.6636
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3 1.65445
PCNA proliferating cell nuclear antigen 1.64865
GDF15 growth differentiation factor 15 1.64842
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 1.64775
GPX1 glutathione peroxidase 1 1.64326
PPARG peroxisome proliferator-activated receptor gamma 1.63921
CLU clusterin 1.63877
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 1.63428
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 1.62691
FLT1 fms-related tyrosine kinase 1 1.62624
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 1.6229
CTSL cathepsin L 1.62199
CD44 CD44 molecule (Indian blood group) 1.62083
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.61897
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 1.61897
BIRC5 baculoviral IAP repeat containing 5 1.61107
KLF6 Kruppel-like factor 6 1.61084
BUB3 BUB3 mitotic checkpoint protein 1.61037
CASP1 caspase 1, apoptosis-related cysteine peptidase 1.60244
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.59896
CD2AP CD2-associated protein 1.59638
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 1.59591
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 1.59334
EPOR erythropoietin receptor 1.58936
PARP1 poly (ADP-ribose) polymerase 1 1.58208
GCLM glutamate-cysteine ligase, modifier subunit 1.58137
SAT1 spermidine/spermine N1-acetyltransferase 1 1.58113
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin) 1.57688
NPPB natriuretic peptide B 1.57186
MAPK14 mitogen-activated protein kinase 14 1.57066
GSTT1 glutathione S-transferase theta 1 1.57018
NGF nerve growth factor (beta polypeptide) 1.56435
RRM2 ribonucleotide reductase M2 1.56386
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 1.56239
GCLC glutamate-cysteine ligase, catalytic subunit 1.55797
GPX3 glutathione peroxidase 3 1.55255
EDNRB endothelin receptor type B 1.55255
GAMT guanidinoacetate N-methyltransferase 1.54669
TEK TEK tyrosine kinase, endothelial 1.54669
MAPK1 mitogen-activated protein kinase 1 1.54596
VIM vimentin 1.54159
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.53357
ECHS1 enoyl CoA hydratase, short chain, 1, mitochondrial 1.53283
NRP1 neuropilin 1 1.53234
CXCL8 chemokine (C-X-C motif) ligand 8 1.51456
HSPA1A heat shock 70kDa protein 1A 1.5123
OAT ornithine aminotransferase 1.51155
CTSD cathepsin D 1.51055
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4 1.50928
FDFT1 farnesyl-diphosphate farnesyltransferase 1 1.507
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 1.50549
NFE2L2 nuclear factor, erythroid 2-like 2 1.50448
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.50323
MMP2 matrix metallopeptidase 2 1.50273
IGFBP5 insulin-like growth factor binding protein 5 1.50043
PRNP prion protein 1.49813
S100A9 S100 calcium binding protein A9 1.49813
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 1.49278
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6 1.48813
NOS1 nitric oxide synthase 1 (neuronal) 1.48787
MAPK8 mitogen-activated protein kinase 8 1.48556
CALR calreticulin 1.48556
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 1.48119
CASP6 caspase 6, apoptosis-related cysteine peptidase 1.47915
SERINC3 serine incorporator 3 1.47762
CYCS cytochrome c, somatic 1.47478
NQO1 NAD(P)H dehydrogenase, quinone 1 1.47426
ATF3 activating transcription factor 3 1.474
FN1 fibronectin 1 1.474
NBN nibrin 1.46883
HAVCR1 hepatitis A virus cellular receptor 1 1.46807
COL4A1 collagen, type IV, alpha 1 1.46515
DCXR dicarbonyl/L-xylulose reductase 1.46462
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.46251
CCNG1 cyclin G1 1.4612
CTGF connective tissue growth factor 1.45484
DPP4 dipeptidyl-peptidase 4 1.45141
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.45063
ACO2 aconitase 2, mitochondrial 1.44599
APOE apolipoprotein E 1.44327
STAT1 signal transducer and activator of transcription 1, 91kDa 1.44056
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 1.43809
UNG uracil-DNA glycosylase 1.43809
GSK3B glycogen synthase kinase 3 beta 1.43646
NR1I2 nuclear receptor subfamily 1, group I, member 2 1.43401
LEP leptin 1.4332
SMAD2 SMAD family member 2 1.42804
PDE4B phosphodiesterase 4B, cAMP-specific 1.42804
CCND1 cyclin D1 1.42616
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 1.42535
TRIB3 tribbles pseudokinase 3 1.4202
IGFBP1 insulin-like growth factor binding protein 1 1.41856
BTG2 BTG family, member 2 1.41667
ATF4 activating transcription factor 4 1.41505
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 1.41424
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 1.41174
C3 complement component 3 1.4098
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 1.4087
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.40815
HSPE1 heat shock 10kDa protein 1 1.40623
MAPK3 mitogen-activated protein kinase 3 1.40623
CBR1 carbonyl reductase 1 1.40401
TIMP2 TIMP metallopeptidase inhibitor 2 1.40316
MMP3 matrix metallopeptidase 3 1.40148
TAGLN transgelin 1.39702
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.39563
BID BH3 interacting domain death agonist 1.39282
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 1.39142
EGF epidermal growth factor 1.38891
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 1.38584
DHFR dihydrofolate reductase 1.38584
RB1 retinoblastoma 1 1.38469
TPMT thiopurine S-methyltransferase 1.38327
NR1I3 nuclear receptor subfamily 1, group I, member 3 1.38156
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 1.37902
TYMS thymidylate synthetase 1.37846
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.37789
PRC1 protein regulator of cytokinesis 1 1.37418
CDK2 cyclin-dependent kinase 2 1.37418
DTYMK deoxythymidylate kinase (thymidylate kinase) 1.37303
SLC22A9 solute carrier family 22 (organic anion transporter), member 9 1.3682
BIRC3 baculoviral IAP repeat containing 3 1.36591
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 1.36418
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 1.35849
GPX2 glutathione peroxidase 2 1.35386
RUNX3 runt-related transcription factor 3 1.35386
FADS1 fatty acid desaturase 1 1.35299
PTK2 protein tyrosine kinase 2 1.35184
IL2 interleukin 2 1.35069
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 1.34983
FANCI Fanconi anemia, complementation group I 1.34926
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.34869
MKI67 marker of proliferation Ki-67 1.34811
MEP1B meprin A, beta 1.34752
APOB apolipoprotein B 1.34401
ETFB electron-transfer-flavoprotein, beta polypeptide 1.34053
ACSL6 acyl-CoA synthetase long-chain family member 6 1.34053
MAP2K2 mitogen-activated protein kinase kinase 2 1.34024
DKK1 dickkopf WNT signaling pathway inhibitor 1 1.3388
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B 1.3388
PLAT plasminogen activator, tissue 1.33642
H2AFX H2A histone family, member X 1.33642
IL18 interleukin 18 1.33642
CFLAR CASP8 and FADD-like apoptosis regulator 1.33612
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase 1.33583
G6PD glucose-6-phosphate dehydrogenase 1.33494
BAD BCL2-associated agonist of cell death 1.33494
ANGPTL4 angiopoietin-like 4 1.33434
SESN2 sestrin 2 1.33316
TXNIP thioredoxin interacting protein 1.33228
TLR4 toll-like receptor 4 1.33228
SRGN serglycin 1.33169
ANXA1 annexin A1 1.33052
CCNB2 cyclin B2 1.33052
CSF1 colony stimulating factor 1 (macrophage) 1.32786
MCM4 minichromosome maintenance complex component 4 1.32786
CXCL2 chemokine (C-X-C motif) ligand 2 1.32518
COL3A1 collagen, type III, alpha 1 1.32488
PPP1R15A protein phosphatase 1, regulatory subunit 15A 1.32458
SLCO2A1 solute carrier organic anion transporter family, member 2A1 1.3231
BDH1 3-hydroxybutyrate dehydrogenase, type 1 1.3231
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4 1.32221
PHYH phytanoyl-CoA 2-hydroxylase 1.31897
CPSF6 cleavage and polyadenylation specific factor 6, 68kDa 1.31716
NPHS1 nephrosis 1, congenital, Finnish type (nephrin) 1.31506
EGFR epidermal growth factor receptor 1.31178
CFI complement factor I 1.31089
DUSP1 dual specificity phosphatase 1 1.30727
GLO1 glyoxalase I 1.30696
UGT1A3 UDP glucuronosyltransferase 1 family, polypeptide A3 1.30666
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 1.30666
ENO1 enolase 1, (alpha) 1.30451
XBP1 X-box binding protein 1 1.30451
EIF1AX eukaryotic translation initiation factor 1A, X-linked 1.30299
BTG3 BTG family, member 3 1.30299
LCN2 lipocalin 2 1.29936
UGT1A10 UDP glucuronosyltransferase 1 family, polypeptide A10 1.29905
KLF4 Kruppel-like factor 4 (gut) 1.29657
HSPB1 heat shock 27kDa protein 1 1.29533
SRM spermidine synthase 1.29502
GSR glutathione reductase 1.29502
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 1.2941
CPT1A carnitine palmitoyltransferase 1A (liver) 1.29225
UGT1A6 UDP glucuronosyltransferase 1 family, polypeptide A6 1.29225
CDC6 cell division cycle 6 1.29164
POR P450 (cytochrome) oxidoreductase 1.29133
WIPI1 WD repeat domain, phosphoinositide interacting 1 1.29133
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 1.28672
BDKRB1 bradykinin receptor B1 1.28395
ANGPT1 angiopoietin 1 1.28395
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 1.28303
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 1.2818
DPYD dihydropyrimidine dehydrogenase 1.2818
LMNA lamin A/C 1.2818
GEM GTP binding protein overexpressed in skeletal muscle 1.28027
ACADL acyl-CoA dehydrogenase, long chain 1.28027
AURKA aurora kinase A 1.27966
THNSL2 threonine synthase-like 2 (S. cerevisiae) 1.27689
CXCL12 chemokine (C-X-C motif) ligand 12 1.27378
MBP myelin basic protein 1.27255
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 1.27255
GSTM1 glutathione S-transferase mu 1 1.27193
PAIP1 poly(A) binding protein interacting protein 1 1.27101
MFN2 mitofusin 2 1.2707
RFC3 replication factor C (activator 1) 3, 38kDa 1.26947
S1PR1 sphingosine-1-phosphate receptor 1 1.26947
TXNRD1 thioredoxin reductase 1 1.26638
SMAD4 SMAD family member 4 1.26607
AK4 adenylate kinase 4 1.26607
PLAU plasminogen activator, urokinase 1.26545
ACACB acetyl-CoA carboxylase beta 1.26267
S100A11 S100 calcium binding protein A11 1.26267
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide 1.25929
IL12B interleukin 12B 1.25929
ATF5 activating transcription factor 5 1.25929
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 1.25899
ADIPOR2 adiponectin receptor 2 1.25619
EGR2 early growth response 2 1.25463
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 1.25463
PRDX2 peroxiredoxin 2 1.25463
SOD1 superoxide dismutase 1, soluble 1.254
ECI1 enoyl-CoA delta isomerase 1 1.25276
ANPEP alanyl (membrane) aminopeptidase 1.25276
KDR kinase insert domain receptor 1.24997
MYH6 myosin, heavy chain 6, cardiac muscle, alpha 1.24966
DUT deoxyuridine triphosphatase 1.24966
ACAT1 acetyl-CoA acetyltransferase 1 1.24966
SLC22A11 solute carrier family 22 (organic anion/urate transporter), member 11 1.24843
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 1.24687
VCL vinculin 1.24623
CES2 carboxylesterase 2 1.24623
RPS6 ribosomal protein S6 1.24401
AKAP12 A kinase (PRKA) anchor protein 12 1.24307
SARS seryl-tRNA synthetase 1.24275
HSPA9 heat shock 70kDa protein 9 (mortalin) 1.23993
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 1.23993
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 1.23993
FAAH fatty acid amide hydrolase 1.23993
CDK1 cyclin-dependent kinase 1 1.2352
HLA-F major histocompatibility complex, class I, F 1.23392
KLF2 Kruppel-like factor 2 1.23392
CCL5 chemokine (C-C motif) ligand 5 1.23392
TYMP thymidine phosphorylase 1.2336
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 1.2336
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) 1.2336
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1 1.23265
SELL selectin L 1.23074
S100A8 S100 calcium binding protein A8 1.22948
STMN1 stathmin 1 1.22948
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 1.22758
SESN1 sestrin 1 1.22758
TANK TRAF family member-associated NFKB activator 1.22727
PHIP pleckstrin homology domain interacting protein 1.22727
APAF1 apoptotic peptidase activating factor 1 1.22566
TOPBP1 topoisomerase (DNA) II binding protein 1 1.22209
SPTLC2 serine palmitoyltransferase, long chain base subunit 2 1.22209
CYLD cylindromatosis (turban tumor syndrome) 1.22209
KNG1 kininogen 1 1.21951
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.21887
STIP1 stress-induced phosphoprotein 1 1.21855
WEE1 WEE1 G2 checkpoint kinase 1.21855
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.21855
ANXA5 annexin A5 1.21759
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin) 1.21727
SMAD7 SMAD family member 7 1.21567
SCD stearoyl-CoA desaturase (delta-9-desaturase) 1.21567
NME1 NME/NM23 nucleoside diphosphate kinase 1 1.21567
S100A10 S100 calcium binding protein A10 1.21567
CYFIP2 cytoplasmic FMR1 interacting protein 2 1.21239
ATP5D ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit 1.21239
ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B) 1.21239
KEAP1 kelch-like ECH-associated protein 1 1.21173
BIRC2 baculoviral IAP repeat containing 2 1.21173
BDKRB2 bradykinin receptor B2 1.21011
ACSL1 acyl-CoA synthetase long-chain family member 1 1.20978
ASNS asparagine synthetase (glutamine-hydrolyzing) 1.20978
TXN thioredoxin 1.20978
FYN FYN proto-oncogene, Src family tyrosine kinase 1.20978
MUT methylmalonyl CoA mutase 1.20751
XDH xanthine dehydrogenase 1.20751
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 1.20751
CAPN2 calpain 2, (m/II) large subunit 1.20719
VWA5A von Willebrand factor A domain containing 5A 1.20719
IRS1 insulin receptor substrate 1 1.2059
CYR61 cysteine-rich, angiogenic inducer, 61 1.2059
FAM171A1 family with sequence similarity 171, member A1 1.20493
PYROXD2 pyridine nucleotide-disulphide oxidoreductase domain 2 1.20493
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.2046
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1 1.2046
CBS cystathionine-beta-synthase 1.20427
FNBP1 formin binding protein 1 1.20295
FANCG Fanconi anemia, complementation group G 1.20295
HSDL2 hydroxysteroid dehydrogenase like 2 1.20295
MCL1 myeloid cell leukemia 1 1.20064
UGT1A9 UDP glucuronosyltransferase 1 family, polypeptide A9 1.20031
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 1.19933
SFXN1 sideroflexin 1 1.19835
IL1RN interleukin 1 receptor antagonist 1.19477
NASP nuclear autoantigenic sperm protein (histone-binding) 1.19379
ABHD4 abhydrolase domain containing 4 1.19379
ACSS2 acyl-CoA synthetase short-chain family member 2 1.19379
TGFBR1 transforming growth factor, beta receptor 1 1.19345
INHBE inhibin, beta E 1.19312
CLDN1 claudin 1 1.19312
TGFB2 transforming growth factor, beta 2 1.19279
HSPA1B heat shock 70kDa protein 1B 1.19279
BAK1 BCL2-antagonist/killer 1 1.1908
GRN granulin 1.19047
GJB1 gap junction protein, beta 1, 32kDa 1.19047
ODC1 ornithine decarboxylase 1 1.18981
MGEA5 meningioma expressed antigen 5 (hyaluronidase) 1.18948
DBF4 DBF4 zinc finger 1.18948
NNT nicotinamide nucleotide transhydrogenase 1.18948
MAP3K7 mitogen-activated protein kinase kinase kinase 7 1.18948
CMBL carboxymethylenebutenolidase homolog (Pseudomonas) 1.18915
MARCKS myristoylated alanine-rich protein kinase C substrate 1.18783
CUBN cubilin (intrinsic factor-cobalamin receptor) 1.18751
SOCS3 suppressor of cytokine signaling 3 1.18718
IL15RA interleukin 15 receptor, alpha 1.18718
MSH2 mutS homolog 2 1.18521
SGK1 serum/glucocorticoid regulated kinase 1 1.18193
COL4A2 collagen, type IV, alpha 2 1.18059
GINS1 GINS complex subunit 1 (Psf1 homolog) 1.18059
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) 1.18059
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 1.18026
FASN fatty acid synthase 1.17959
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.17827
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 1.17761
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 1.17728
MYH7 myosin, heavy chain 7, cardiac muscle, beta 1.17728
PC pyruvate carboxylase 1.17662
GLDC glycine dehydrogenase (decarboxylating) 1.17662
RBPMS RNA binding protein with multiple splicing 1.17662
RRAS2 related RAS viral (r-ras) oncogene homolog 2 1.17662
LAMB1 laminin, beta 1 1.17662
KLK1 kallikrein 1 1.17662
EMP3 epithelial membrane protein 3 1.17629
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5 1.17629
TPI1 triosephosphate isomerase 1 1.17464
RAMP2 receptor (G protein-coupled) activity modifying protein 2 1.17268
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5 1.17235
PALLD palladin, cytoskeletal associated protein 1.17235
LHB luteinizing hormone beta polypeptide 1.17202
CTSB cathepsin B 1.17134
ATG3 autophagy related 3 1.17134
WTAP Wilms tumor 1 associated protein 1.17101
ANXA3 annexin A3 1.16967
MGMT O-6-methylguanine-DNA methyltransferase 1.16967
BLM Bloom syndrome, RecQ helicase-like 1.16833
TP53INP1 tumor protein p53 inducible nuclear protein 1 1.16833
ACTB actin, beta 1.16633
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 1.16434
GFRA1 GDNF family receptor alpha 1 1.16434
USP36 ubiquitin specific peptidase 36 1.16368
NT5C2 5'-nucleotidase, cytosolic II 1.16368
CAV1 caveolin 1, caveolae protein, 22kDa 1.16302
S100A4 S100 calcium binding protein A4 1.16236
CD14 CD14 molecule 1.16137
MAPK9 mitogen-activated protein kinase 9 1.1607
TMSB4X thymosin beta 4, X-linked 1.16035
ACOX2 acyl-CoA oxidase 2, branched chain 1.16035
DDIT4 DNA-damage-inducible transcript 4 1.15797
BTG1 B-cell translocation gene 1, anti-proliferative 1.15729
ANGPT2 angiopoietin 2 1.15661
IER5 immediate early response 5 1.15627
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 1.15627
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 1.15627
LYPLAL1 lysophospholipase-like 1 1.15593
SLC6A18 solute carrier family 6 (neutral amino acid transporter), member 18 1.15593
PRL prolactin 1.1556
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 1.1556
PLIN2 perilipin 2 1.15492
FOXO1 forkhead box O1 1.15492
APP amyloid beta (A4) precursor protein 1.15458
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.15458
AKR1C3 aldo-keto reductase family 1, member C3 1.1529
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 1.15256
CTSH cathepsin H 1.15256
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1 1.15256
SQSTM1 sequestosome 1 1.15122
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 1.14954
GCSH glycine cleavage system protein H (aminomethyl carrier) 1.14919
FDXR ferredoxin reductase 1.14885
COPG1 coatomer protein complex, subunit gamma 1 1.14885
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 1.1485
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8 1.14781
NOX4 NADPH oxidase 4 1.14781
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 1.14713
AKR1C1 aldo-keto reductase family 1, member C1 1.14644
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 1.14644
CP ceruloplasmin (ferroxidase) 1.14302
KIFAP3 kinesin-associated protein 3 1.14166
BIRC6 baculoviral IAP repeat containing 6 1.14166
C10ORF10 chromosome 10 open reading frame 10 1.14132
NINJ1 ninjurin 1 1.14098
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.13997
CALB1 calbindin 1, 28kDa 1.13758
MAGED1 melanoma antigen family D1 1.13484
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 1.13484
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 1.13415
IDI1 isopentenyl-diphosphate delta isomerase 1 1.13381
MCAM melanoma cell adhesion molecule 1.13381
MUCL1 mucin-like 1 1.13211
PRLR prolactin receptor 1.13177
HMGB1 high mobility group box 1 1.13177
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 1.13177
HMGA2 high mobility group AT-hook 2 1.13041
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3 1.13041
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 1.1294
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4 1.12838
FKBP5 FK506 binding protein 5 1.12737
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 1.12703
C1QA complement component 1, q subcomponent, A chain 1.12668
CTH cystathionine gamma-lyase 1.1253
IGFBP3 insulin-like growth factor binding protein 3 1.12461
ZMAT3 zinc finger, matrin-type 3 1.12357
DUSP10 dual specificity phosphatase 10 1.12323
MVP major vault protein 1.12323
BMP4 bone morphogenetic protein 4 1.12288
TMEM43 transmembrane protein 43 1.12185
FOXO3 forkhead box O3 1.12082
AXL AXL receptor tyrosine kinase 1.12014
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein 1.1198
KRT17 keratin 17, type I 1.1198
AVP arginine vasopressin 1.11877
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 1.11673
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae) 1.11673
ALAS2 5'-aminolevulinate synthase 2 1.11673
LSG1 large 60S subunit nuclear export GTPase 1 1.11673
PDK4 pyruvate dehydrogenase kinase, isozyme 4 1.11673
FAM212B family with sequence similarity 212, member B 1.11639
POMC proopiomelanocortin 1.11639
PABPN1 poly(A) binding protein, nuclear 1 1.11606
CCL7 chemokine (C-C motif) ligand 7 1.11431
TJP1 tight junction protein 1 1.11431
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 1.1122
NPC1L1 NPC1-like 1 1.10977
MSH3 mutS homolog 3 1.10977
GSTA3 glutathione S-transferase alpha 3 1.10977
RFTN1 raftlin, lipid raft linker 1 1.10942
PHLDA2 pleckstrin homology-like domain, family A, member 2 1.10665
LGALS3 lectin, galactoside-binding, soluble, 3 1.10596
SMC3 structural maintenance of chromosomes 3 1.10388
CIDEB cell death-inducing DFFA-like effector b 1.10388
LZTFL1 leucine zipper transcription factor-like 1 1.10388
MAP2K1 mitogen-activated protein kinase kinase 1 1.10388
DGAT1 diacylglycerol O-acyltransferase 1 1.10353
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 1.10246
WDR26 WD repeat domain 26 1.09786
GMDS GDP-mannose 4,6-dehydratase 1.09786
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 1.09786
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 1.09681
RGS2 regulator of G-protein signaling 2 1.09576
TRIM28 tripartite motif containing 28 1.09262
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein 1.09262
KIF3A kinesin family member 3A 1.09226
DRAM1 DNA-damage regulated autophagy modulator 1 1.09226
CA2 carbonic anhydrase II 1.0919
TOP2A topoisomerase (DNA) II alpha 170kDa 1.09119
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 1.09119
ZEB1 zinc finger E-box binding homeobox 1 1.09083
GPR20 G protein-coupled receptor 20 1.08975
UGT3A1 UDP glycosyltransferase 3 family, polypeptide A1 1.0894
ZWINT ZW10 interacting kinetochore protein 1.08762
NES nestin 1.08762
GNAT1 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 1.08655
ANXA2 annexin A2 1.08584
BBC3 BCL2 binding component 3 1.08584
LCAT lecithin-cholesterol acyltransferase 1.08478
GLS glutaminase 1.08478
LBP lipopolysaccharide binding protein 1.08478
CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11 1.08478
NFKBIZ nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta 1.08442
CYBA cytochrome b-245, alpha polypeptide 1.08407
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 1.08407
ADM adrenomedullin 1.08407
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 1.08231
MPZ myelin protein zero 1.08161
KIF23 kinesin family member 23 1.08161
PIR pirin (iron-binding nuclear protein) 1.08161
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 1.08161
PRDX3 peroxiredoxin 3 1.08161
KITLG KIT ligand 1.08161
DPP3 dipeptidyl-peptidase 3 1.08126
NME7 NME/NM23 family member 7 1.08126
AARS alanyl-tRNA synthetase 1.08126
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 1.08126
FGF2 fibroblast growth factor 2 (basic) 1.08019
LTA lymphotoxin alpha 1.07875
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) 1.07875
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) 1.07875
TRIM63 tripartite motif containing 63, E3 ubiquitin protein ligase 1.0766
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase 1.07625
HEXA hexosaminidase A (alpha polypeptide) 1.07625
TFRC transferrin receptor 1.07625
TGM2 transglutaminase 2 1.07625
FABP1 fatty acid binding protein 1, liver 1.07625
ACOT4 acyl-CoA thioesterase 4 1.07625
MAP3K12 mitogen-activated protein kinase kinase kinase 12 1.07589
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2 1.07589
RGN regucalcin 1.07589
TJP3 tight junction protein 3 1.07589
HIST1H2BC histone cluster 1, H2bc 1.07589
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 1.07589
PRDX1 peroxiredoxin 1 1.07447
CTSS cathepsin S 1.07305
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 1.07269
HMMR hyaluronan-mediated motility receptor (RHAMM) 1.07269
UBC ubiquitin C 1.07269
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 1.07269
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 1.07093
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1) 1.07093
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 1.07093
NMT2 N-myristoyltransferase 2 1.07093
CPT2 carnitine palmitoyltransferase 2 1.06987
DNMT1 DNA (cytosine-5-)-methyltransferase 1 1.06881
PDIA4 protein disulfide isomerase family A, member 4 1.06698
UGCG UDP-glucose ceramide glucosyltransferase 1.06698
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 1.06698
DES desmin 1.06698
KRT8 keratin 8, type II 1.06698
POLM polymerase (DNA directed), mu 1.06588
PLAC8 placenta-specific 8 1.06588
ABCB5 ATP-binding cassette, sub-family B (MDR/TAP), member 5 1.06515
TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae) 1.06479
GEMIN8 gem (nuclear organelle) associated protein 8 1.06479
ASS1 argininosuccinate synthase 1 1.06406
ARC activity-regulated cytoskeleton-associated protein 1.06152
RAD50 RAD50 homolog (S. cerevisiae) 1.06152
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 1.0608
KLF5 Kruppel-like factor 5 (intestinal) 1.05864
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 1.05864
MT1X metallothionein 1X 1.0561
BRCA1 breast cancer 1, early onset 1.0561
H1FX H1 histone family, member X 1.05573
CD9 CD9 molecule 1.05573
TUBA1A tubulin, alpha 1a 1.05573
CST7 cystatin F (leukocystatin) 1.05461
CYP8B1 cytochrome P450, family 8, subfamily B, polypeptide 1 1.05312
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 1.05312
TAC1 tachykinin, precursor 1 1.05274
MAOA monoamine oxidase A 1.05237
CD151 CD151 molecule (Raph blood group) 1.05126
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 1.05126
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 1.05015
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 1.05015
HSPA2 heat shock 70kDa protein 2 1.05015
FOSL2 FOS-like antigen 2 1.05015
SELE selectin E 1.04868
ETFDH electron-transferring-flavoprotein dehydrogenase 1.04647
UBE2N ubiquitin-conjugating enzyme E2N 1.04647
NUPR1 nuclear protein, transcriptional regulator, 1 1.04538
ACO1 aconitase 1, soluble 1.04501
NPVF neuropeptide VF precursor 1.04352
GFRA2 GDNF family receptor alpha 2 1.04201
TTR transthyretin 1.04163
OXCT1 3-oxoacid CoA transferase 1 1.04163
GRINA glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) 1.04163
BAAT bile acid CoA:amino acid N-acyltransferase 1.04163
PLP2 proteolipid protein 2 (colonic epithelium-enriched) 1.04163
KCNK1 potassium channel, two pore domain subfamily K, member 1 1.04163
CYC1 cytochrome c-1 1.04163
GULOP gulonolactone (L-) oxidase, pseudogene 1.04163
ACY1 aminoacylase 1 1.04163
TCF3 transcription factor 3 1.04163
SRSF3 serine/arginine-rich splicing factor 3 1.04163
AGTR1 angiotensin II receptor, type 1 1.03976
PKLR pyruvate kinase, liver and RBC 1.03939
HADH hydroxyacyl-CoA dehydrogenase 1.03939
GSTO1 glutathione S-transferase omega 1 1.03939
ERBB2 erb-b2 receptor tyrosine kinase 2 1.03827
GBP1 guanylate binding protein 1, interferon-inducible 1.03752
NFE2L1 nuclear factor, erythroid 2-like 1 1.03715
DPYSL4 dihydropyrimidinase-like 4 1.03715
SLC13A2 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2 1.03715
TRPV6 transient receptor potential cation channel, subfamily V, member 6 1.03715
VGF VGF nerve growth factor inducible 1.03715
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 1.03678
ABHD2 abhydrolase domain containing 2 1.03678
VDAC1 voltage-dependent anion channel 1 1.03678
ECH1 enoyl CoA hydratase 1, peroxisomal 1.03678
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) 1.03456
LTF lactotransferrin 1.03419
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) 1.03382
SLMO2 slowmo homolog 2 (Drosophila) 1.03382
SS18L2 synovial sarcoma translocation gene on chromosome 18-like 2 1.03345
MAPT microtubule-associated protein tau 1.03308
SP1 Sp1 transcription factor 1.03308
CCL3 chemokine (C-C motif) ligand 3 1.03271
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 1.03271
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 1.03271
ATAD2 ATPase family, AAA domain containing 2 1.03235
RIOK3 RIO kinase 3 1.03235
CCS copper chaperone for superoxide dismutase 1.03235
JAK1 Janus kinase 1 1.03197
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 1.03197
CCNA2 cyclin A2 1.03122
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide 1.02933
GSTA2 glutathione S-transferase alpha 2 1.02896
IL16 interleukin 16 1.02858
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 1.02821
AK3 adenylate kinase 3 1.02821
ATM ATM serine/threonine kinase 1.02821
ASL argininosuccinate lyase 1.02821
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 1.02821
PCTP phosphatidylcholine transfer protein 1.02821
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 1.02821
BMP1 bone morphogenetic protein 1 1.02783
BIN1 bridging integrator 1 1.02783
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2 1.02485
TF transferrin 1.02485
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 1.02485
ADCK2 aarF domain containing kinase 2 1.0241
GLB1L galactosidase, beta 1-like 1.0241
HSPB6 heat shock protein, alpha-crystallin-related, B6 1.02373
DHRS2 dehydrogenase/reductase (SDR family) member 2 1.02373
PECR peroxisomal trans-2-enoyl-CoA reductase 1.02373
E2F3 E2F transcription factor 3 1.02373
DHCR24 24-dehydrocholesterol reductase 1.02188
KIF20A kinesin family member 20A 1.02151
IGF1R insulin-like growth factor 1 receptor 1.02151
CRIP1 cysteine-rich protein 1 (intestinal) 1.01966
STK39 serine threonine kinase 39 1.01966
GPT2 glutamic pyruvate transaminase (alanine aminotransferase) 2 1.01966
LY96 lymphocyte antigen 96 1.01966
RPL23 ribosomal protein L23 1.01966
POLG polymerase (DNA directed), gamma 1.01966
UGT2B7 UDP glucuronosyltransferase 2 family, polypeptide B7 1.01966
TSPO translocator protein (18kDa) 1.01928
CCNG2 cyclin G2 1.01928
GLIPR1 GLI pathogenesis-related 1 1.01928
NFIC nuclear factor I/C (CCAAT-binding transcription factor) 1.01928
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1 1.01701
THRSP thyroid hormone responsive 1.01663
GHR growth hormone receptor 1.01663
HSF1 heat shock transcription factor 1 1.01663
CDC25B cell division cycle 25B 1.01663
ACVR1B activin A receptor, type IB 1.01587
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 1.01587
HAO2 hydroxyacid oxidase 2 (long chain) 1.01549
CLCN3 chloride channel, voltage-sensitive 3 1.01549
PLA1A phospholipase A1 member A 1.01549
CSNK2A2 casein kinase 2, alpha prime polypeptide 1.01549
GM2A GM2 ganglioside activator 1.01512
RGS1 regulator of G-protein signaling 1 1.01512
B3GALNT2 beta-1,3-N-acetylgalactosaminyltransferase 2 1.01512
GPR137C G protein-coupled receptor 137C 1.01512
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 1.01437
DIABLO diablo, IAP-binding mitochondrial protein 1.01437
MAGEA6 melanoma antigen family A6 1.01212
EPAS1 endothelial PAS domain protein 1 1.01212
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1 1.01174
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase 1.01174
ACTN1 actinin, alpha 1 1.01137
RFC5 replication factor C (activator 1) 5, 36.5kDa 1.01137
DDB2 damage-specific DNA binding protein 2, 48kDa 1.01137
DLAT dihydrolipoamide S-acetyltransferase 1.01137
DBN1 drebrin 1 1.01099
KAT2B K(lysine) acetyltransferase 2B 1.01099
BCAR3 breast cancer anti-estrogen resistance 3 1.01099