BAD Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description BCL2-associated agonist of cell death|The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 572)
External Link https://ncbi.nlm.nih.gov/gene/572
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Genes

498 genes differentially expressed following the BAD gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 0.0195996
LCN2 lipocalin 2 0.0171837
S100A9 S100 calcium binding protein A9 0.0167194
LTF lactotransferrin 0.0151437
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) 0.0139507
CFB complement factor B 0.0137468
CXCL8 chemokine (C-X-C motif) ligand 8 0.0135385
ATF3 activating transcription factor 3 0.013225
CCL20 chemokine (C-C motif) ligand 20 0.0129837
S100A8 S100 calcium binding protein A8 0.01293
HSPA1A heat shock 70kDa protein 1A 0.0125481
HSPB1 heat shock 27kDa protein 1 0.0124751
S100A12 S100 calcium binding protein A12 0.0119548
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 0.0114665
HIST1H2AC histone cluster 1, H2ac 0.0114482
IL1RN interleukin 1 receptor antagonist 0.0112903
S100P S100 calcium binding protein P 0.0111878
RPS4Y1 ribosomal protein S4, Y-linked 1 0.0111271
PDZK1IP1 PDZK1 interacting protein 1 0.0106875
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) 0.0106022
S100A7 S100 calcium binding protein A7 0.0105949
NIBAN1 niban apoptosis regulator 1 0.0103224
LY96 lymphocyte antigen 96 0.0101799
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 0.0101482
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 0.0100008
JUNB jun B proto-oncogene 0.00993624
CXCL13 chemokine (C-X-C motif) ligand 13 0.00991494
HSPH1 heat shock 105kDa/110kDa protein 1 0.00989163
SAT1 spermidine/spermine N1-acetyltransferase 1 0.00983719
C1ORF54 chromosome 1 open reading frame 54 0.00983167
IFITM1 interferon induced transmembrane protein 1 0.00972947
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 0.00967489
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.00957232
CEMIP cell migration inducing protein, hyaluronan binding 0.00954125
IFRD1 interferon-related developmental regulator 1 0.00953056
BCL2A1 BCL2-related protein A1 0.00951092
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.00941077
PPP1R3C protein phosphatase 1, regulatory subunit 3C 0.00918788
LPAR6 lysophosphatidic acid receptor 6 0.00914997
PI3 peptidase inhibitor 3, skin-derived 0.00914888
HSPA2 heat shock 70kDa protein 2 0.00909253
ASNS asparagine synthetase (glutamine-hydrolyzing) 0.00898519
PLBD1 phospholipase B domain containing 1 0.00896968
PADI2 peptidyl arginine deiminase, type II 0.00892278
CRYAB crystallin, alpha B 0.00890994
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.00885867
DDIT3 DNA-damage-inducible transcript 3 0.00881271
RNF167 ring finger protein 167 0.00877755
MBOAT7 membrane bound O-acyltransferase domain containing 7 0.00876436
CHI3L2 chitinase 3-like 2 0.00871415
KLK10 kallikrein-related peptidase 10 0.00865875
JCHAIN joining chain of multimeric IgA and IgM 0.00863971
ANXA1 annexin A1 0.00860802
IFI27 interferon, alpha-inducible protein 27 0.00850998
RHOB ras homolog family member B 0.00850893
LXN latexin 0.00850716
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.00850679
TSC22D1 TSC22 domain family, member 1 0.0084202
KDM5D lysine (K)-specific demethylase 5D 0.00840314
HIST1H2BD histone cluster 1, H2bd 0.0083423
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.00834024
MMP7 matrix metallopeptidase 7 0.0083387
MXI1 MAX interactor 1, dimerization protein 0.00832886
MYO1C myosin IC 0.0083211
ALOX5 arachidonate 5-lipoxygenase 0.00829739
GYPC glycophorin C (Gerbich blood group) 0.00825011
BEX4 brain expressed, X-linked 4 0.00824144
FABP7 fatty acid binding protein 7, brain 0.00821057
PYCARD PYD and CARD domain containing 0.00817734
DDIT4 DNA-damage-inducible transcript 4 0.00816525
GRB7 growth factor receptor-bound protein 7 0.00813379
PON2 paraoxonase 2 0.00813094
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.00810178
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 0.00800906
KLK6 kallikrein-related peptidase 6 0.00796569
GIMAP4 GTPase, IMAP family member 4 0.00795257
HIST1H2BK histone cluster 1, H2bk 0.00789575
CHIC2 cysteine-rich hydrophobic domain 2 0.0078797
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.00787204
CSRP2 cysteine and glycine-rich protein 2 0.00785268
ALOX5AP arachidonate 5-lipoxygenase-activating protein 0.00780881
DEFB1 defensin, beta 1 0.00780581
ECM1 extracellular matrix protein 1 0.0077744
CD48 CD48 molecule 0.0077669
SELL selectin L 0.00775102
IL1B interleukin 1, beta 0.00774847
IFITM3 interferon induced transmembrane protein 3 0.00772029
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.00769632
ETHE1 ethylmalonic encephalopathy 1 0.00769424
EVI2A ecotropic viral integration site 2A 0.00767019
SOD2 superoxide dismutase 2, mitochondrial 0.00766552
CXCL2 chemokine (C-X-C motif) ligand 2 0.00764206
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 0.00760075
FAIM Fas apoptotic inhibitory molecule 0.00758002
IER5 immediate early response 5 0.00751754
C1S complement component 1, s subcomponent 0.00749987
SARS1 seryl-tRNA synthetase 1 0.0074834
CD69 CD69 molecule 0.00747007
MXRA7 matrix-remodelling associated 7 0.00739704
ORC5 origin recognition complex, subunit 5 0.0073721
MALL mal, T-cell differentiation protein-like 0.00734856
AQP1 aquaporin 1 (Colton blood group) 0.00734258
GMPR guanosine monophosphate reductase 0.00734061
HACD1 3-hydroxyacyl-CoA dehydratase 1 0.00733466
JMJD6 jumonji domain containing 6 0.00730085
IL1R2 interleukin 1 receptor, type II 0.00729891
FOSL2 FOS-like antigen 2 0.00727419
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 0.00724798
CD59 CD59 molecule, complement regulatory protein 0.00723558
TPM4 tropomyosin 4 0.00721371
KLF2 Kruppel-like factor 2 0.00718878
STK38L serine/threonine kinase 38 like 0.00717525
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 0.00713368
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 0.00712432
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7 0.00711547
AQP9 aquaporin 9 0.007071
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 0.00704313
CST7 cystatin F (leukocystatin) 0.00701766
SCEL sciellin 0.00699378
GLRX glutaredoxin (thioltransferase) 0.00695897
GPR65 G protein-coupled receptor 65 0.00695236
ELL2 elongation factor, RNA polymerase II, 2 0.00692693
RSL1D1 ribosomal L1 domain containing 1 0.00691603
HK2 hexokinase 2 0.00691558
G6PD glucose-6-phosphate dehydrogenase 0.00684659
LCK LCK proto-oncogene, Src family tyrosine kinase 0.00684312
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 0.00684003
TUBA4A tubulin, alpha 4a 0.00680338
YPEL5 yippee-like 5 (Drosophila) 0.0067949
MBNL2 muscleblind-like splicing regulator 2 0.00679075
STEAP1 six transmembrane epithelial antigen of the prostate 1 0.00678347
DEFB4A defensin, beta 4A 0.00676902
ZNF430 zinc finger protein 430 0.00671182
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase 0.00669275
TRIP6 thyroid hormone receptor interactor 6 0.00668171
KLRB1 killer cell lectin-like receptor subfamily B, member 1 0.00666025
BET1 Bet1 golgi vesicular membrane trafficking protein 0.00662863
GABARAPL1 GABA(A) receptor-associated protein like 1 0.00660456
SLPI secretory leukocyte peptidase inhibitor 0.00660119
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.0065944
ZNHIT1 zinc finger, HIT-type containing 1 0.006592
GOLT1B golgi transport 1B 0.0065837
FAM8A1 family with sequence similarity 8, member A1 0.00657835
EGR3 early growth response 3 0.00657607
RNASE6 ribonuclease, RNase A family, k6 0.00657474
NT5C2 5'-nucleotidase, cytosolic II 0.00657016
LST1 leukocyte specific transcript 1 0.00657014
EGR1 early growth response 1 0.00654486
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 0.00652272
C10ORF10 chromosome 10 open reading frame 10 0.00649571
BIRC3 baculoviral IAP repeat containing 3 0.0064863
TGM2 transglutaminase 2 0.00645932
MOSPD1 motile sperm domain containing 1 0.00643176
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 0.00642117
KRT15 keratin 15, type I 0.00638157
HIST1H2AE histone cluster 1, H2ae 0.00637726
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.00636985
BTG2 BTG family, member 2 0.00635824
MRPL40 mitochondrial ribosomal protein L40 0.00634211
EHF ets homologous factor 0.00634048
TGIF1 TGFB-induced factor homeobox 1 0.00633401
FCN1 ficolin (collagen/fibrinogen domain containing) 1 0.00630054
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) 0.00629549
RIOK3 RIO kinase 3 0.00629292
ATP6V1F ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F 0.00628269
MET MET proto-oncogene, receptor tyrosine kinase 0.00627719
HSPA6 heat shock 70kDa protein 6 (HSP70B') 0.00626354
PACSIN2 protein kinase C and casein kinase substrate in neurons 2 0.0062566
PRELP proline/arginine-rich end leucine-rich repeat protein 0.00625633
RRAS related RAS viral (r-ras) oncogene homolog 0.00621925
CRISP3 cysteine-rich secretory protein 3 0.00619423
TGFB1 transforming growth factor, beta 1 0.00619148
NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa 0.00618685
ASS1 argininosuccinate synthase 1 0.00617366
CRCT1 cysteine-rich C-terminal 1 0.00615646
MSRB1 methionine sulfoxide reductase B1 0.00615069
ZKSCAN1 zinc finger with KRAB and SCAN domains 1 0.00614916
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 0.00611639
ORC4 origin recognition complex, subunit 4 0.00611306
FKBP11 FK506 binding protein 11, 19 kDa 0.00610418
ACP5 acid phosphatase 5, tartrate resistant 0.00610164
PHF11 PHD finger protein 11 0.0061013
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) 0.00609918
FOXO1 forkhead box O1 0.0060987
WBP5 WW domain binding protein 5 0.00608816
C3 complement component 3 0.00608207
LMOD1 leiomodin 1 (smooth muscle) 0.0060796
GREM1 gremlin 1, DAN family BMP antagonist 0.00607484
IFITM2 interferon induced transmembrane protein 2 0.0060674
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 0.00606492
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.006058
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 0.00603412
NCF4 neutrophil cytosolic factor 4, 40kDa 0.00601752
BUD31 BUD31 homolog (S. cerevisiae) 0.00601714
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1) 0.00601588
BTN3A1 butyrophilin, subfamily 3, member A1 0.00600377
GYG1 glycogenin 1 0.00600346
GATAD1 GATA zinc finger domain containing 1 0.00599637
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 0.00599609
CLEC4A C-type lectin domain family 4, member A 0.00599014
AP1S2 adaptor-related protein complex 1, sigma 2 subunit 0.00598138
HPGDS hematopoietic prostaglandin D synthase 0.00597903
NPY neuropeptide Y 0.00596933
TSPAN31 tetraspanin 31 0.00596804
CAPG capping protein (actin filament), gelsolin-like 0.00595143
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 0.00594824
TRIM22 tripartite motif containing 22 0.00594654
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 0.00594598
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 0.00594222
NEU1 sialidase 1 (lysosomal sialidase) 0.00593592
CAPN3 calpain 3, (p94) 0.00592762
CD177 CD177 molecule 0.00592094
CD300A CD300a molecule 0.00590328
AVPI1 arginine vasopressin-induced 1 0.00589846
SUPT4H1 suppressor of Ty 4 homolog 1 (S. cerevisiae) 0.00589763
TP53TG1 TP53 target 1 (non-protein coding) 0.0058933
S100A14 S100 calcium binding protein A14 0.00588411
IL32 interleukin 32 0.0058807
GPNMB glycoprotein (transmembrane) nmb 0.00585432
SGK1 serum/glucocorticoid regulated kinase 1 0.00585328
C9ORF16 chromosome 9 open reading frame 16 0.00584679
CLCA4 chloride channel accessory 4 0.00582906
EAPP E2F-associated phosphoprotein 0.00581197
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 0.0058021
STXBP2 syntaxin binding protein 2 0.00579899
LCMT1 leucine carboxyl methyltransferase 1 0.00579854
TMBIM1 transmembrane BAX inhibitor motif containing 1 0.00579646
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 0.00579446
TMEM59 transmembrane protein 59 0.00578215
PFDN5 prefoldin subunit 5 0.00578134
TEX10 testis expressed 10 0.00576815
ZBED2 zinc finger, BED-type containing 2 0.0057621
FXYD5 FXYD domain containing ion transport regulator 5 0.00576163
OPTN optineurin 0.00575981
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 0.00575438
ISG15 ISG15 ubiquitin-like modifier 0.00572744
GABARAPL2 GABA(A) receptor-associated protein-like 2 0.00571267
CD3D CD3d molecule, delta (CD3-TCR complex) 0.00570404
SIK1 salt-inducible kinase 1 0.00569748
HBP1 HMG-box transcription factor 1 0.0056912
QPCT glutaminyl-peptide cyclotransferase 0.00568534
XCL1 chemokine (C motif) ligand 1 0.00568305
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) 0.00566995
SLAMF7 SLAM family member 7 0.005664
FPR1 formyl peptide receptor 1 0.00565849
KLK11 kallikrein-related peptidase 11 0.00565014
SP110 SP110 nuclear body protein 0.00564268
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 0.00564015
MAL mal, T-cell differentiation protein 0.0056372

decreased expression

Symbol Name Standardized Value
SPRED2 sprouty-related, EVH1 domain containing 2 -0.0187693
HOXC6 homeobox C6 -0.0115487
MATN2 matrilin 2 -0.0113573
MAP7 microtubule-associated protein 7 -0.0110083
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -0.010932
TXLNA taxilin alpha -0.0100765
PLAAT3 phospholipase A and acyltransferase 3 -0.00938531
PBX3 pre-B-cell leukemia homeobox 3 -0.00908797
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) -0.00904382
DDAH1 dimethylarginine dimethylaminohydrolase 1 -0.00872828
AHNAK AHNAK nucleoprotein -0.00856298
ANXA6 annexin A6 -0.00853481
FASN fatty acid synthase -0.00852777
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 -0.00845413
ANO1 anoctamin 1, calcium activated chloride channel -0.00843998
SLC39A6 solute carrier family 39 (zinc transporter), member 6 -0.00843516
CPT1A carnitine palmitoyltransferase 1A (liver) -0.00840105
SLIT2 slit homolog 2 (Drosophila) -0.00839821
RET ret proto-oncogene -0.00835293
FBP1 fructose-1,6-bisphosphatase 1 -0.00829178
IRX5 iroquois homeobox 5 -0.00827294
SEPP1 selenoprotein P, plasma, 1 -0.00824219
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 -0.00822158
LAMP5 lysosomal-associated membrane protein family, member 5 -0.0082001
ADCY1 adenylate cyclase 1 (brain) -0.00818079
EGFR epidermal growth factor receptor -0.00815277
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 -0.00805593
COLEC12 collectin sub-family member 12 -0.00805521
ENPEP glutamyl aminopeptidase (aminopeptidase A) -0.00796583
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) -0.00796507
NTS neurotensin -0.00793941
SMC1A structural maintenance of chromosomes 1A -0.00791845
GUCY2C guanylate cyclase 2C -0.00791403
SDC2 syndecan 2 -0.00790101
BAD BCL2-associated agonist of cell death -0.00789359
ZW10 zw10 kinetochore protein -0.00787941
TUBB6 tubulin, beta 6 class V -0.0078531
KIF20A kinesin family member 20A -0.00767196
FEN1 flap structure-specific endonuclease 1 -0.00761904
PCDH9 protocadherin 9 -0.00749559
CCND1 cyclin D1 -0.007451
COL10A1 collagen, type X, alpha 1 -0.00743078
GSTA1 glutathione S-transferase alpha 1 -0.0074016
TNS3 tensin 3 -0.00731485
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -0.00725646
HNRNPR heterogeneous nuclear ribonucleoprotein R -0.00723449
MAGEA3 melanoma antigen family A3 -0.00717281
RTN2 reticulon 2 -0.00715365
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) -0.00708851
THBS4 thrombospondin 4 -0.00704584
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic) -0.00704091
SCGB2A2 secretoglobin, family 2A, member 2 -0.00701929
NBPF10 neuroblastoma breakpoint family, member 10 -0.00700965
CXCL14 chemokine (C-X-C motif) ligand 14 -0.00700723
CGA glycoprotein hormones, alpha polypeptide -0.00696125
CSK c-src tyrosine kinase -0.00689657
GAL galanin/GMAP prepropeptide -0.00685665
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 -0.00684159
DKFZP586I1420 uncharacterized protein DKFZp586I1420 -0.00684148
NID1 nidogen 1 -0.00683497
DHFR dihydrofolate reductase -0.00681379
SPRY4 sprouty homolog 4 (Drosophila) -0.00678562
KIF1A kinesin family member 1A -0.00675782
LMNB2 lamin B2 -0.00674564
BEX1 brain expressed, X-linked 1 -0.00674119
NELL2 NEL-like 2 (chicken) -0.00666449
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 -0.00662584
TRIP13 thyroid hormone receptor interactor 13 -0.00662447
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 -0.0066064
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 -0.00659457
BCAT2 branched chain amino-acid transaminase 2, mitochondrial -0.00658599
FKBP5 FK506 binding protein 5 -0.00657157
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 -0.00654436
ADAM28 ADAM metallopeptidase domain 28 -0.00652854
NCAPD3 non-SMC condensin II complex, subunit D3 -0.00648155
CDC20 cell division cycle 20 -0.00647085
THAP12 THAP domain containing 12 -0.00646698
THY1 Thy-1 cell surface antigen -0.00645805
RAB25 RAB25, member RAS oncogene family -0.00645731
E2F2 E2F transcription factor 2 -0.00645352
IRAK1 interleukin-1 receptor-associated kinase 1 -0.00645131
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) -0.00637941
MACROD1 MACRO domain containing 1 -0.00637448
HIP1 huntingtin interacting protein 1 -0.00637422
CHD4 chromodomain helicase DNA binding protein 4 -0.00636918
PPP2R1B protein phosphatase 2, regulatory subunit A, beta -0.00636877
SYBU syntabulin (syntaxin-interacting) -0.00635692
KBTBD11 kelch repeat and BTB (POZ) domain containing 11 -0.00631701
ARHGEF40 Rho guanine nucleotide exchange factor (GEF) 40 -0.00626149
TMSB15A thymosin beta 15a -0.00623929
HOXC10 homeobox C10 -0.00623444
NSD2 nuclear receptor binding SET domain protein 2 -0.00623193
NID2 nidogen 2 (osteonidogen) -0.00621031
COL9A3 collagen, type IX, alpha 3 -0.00618918
CES1 carboxylesterase 1 -0.00615526
DEGS1 delta(4)-desaturase, sphingolipid 1 -0.00615304
ARHGAP32 Rho GTPase activating protein 32 -0.00612078
SWAP70 SWAP switching B-cell complex 70kDa subunit -0.00611081
RBBP4 retinoblastoma binding protein 4 -0.0061018
MAPT microtubule-associated protein tau -0.00606796
FUBP1 far upstream element (FUSE) binding protein 1 -0.00603982
HMGB3 high mobility group box 3 -0.00603795
TCF4 transcription factor 4 -0.00601905
NR2F1 nuclear receptor subfamily 2, group F, member 1 -0.00598632
MAGEA12 melanoma antigen family A12 -0.00598158
XIC X chromosome inactivation center -0.00596646
DDHD2 DDHD domain containing 2 -0.00595961
PNN pinin, desmosome associated protein -0.0059179
FADS1 fatty acid desaturase 1 -0.00589532
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1 -0.00589379
HTATSF1 HIV-1 Tat specific factor 1 -0.00586898
PLLP plasmolipin -0.00585996
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase -0.00585216
CBX1 chromobox homolog 1 -0.00585068
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 -0.00584428
MRPL19 mitochondrial ribosomal protein L19 -0.00584367
DNMT1 DNA (cytosine-5-)-methyltransferase 1 -0.00581807
TIMP3 TIMP metallopeptidase inhibitor 3 -0.00581036
ALCAM activated leukocyte cell adhesion molecule -0.00579996
CPSF6 cleavage and polyadenylation specific factor 6, 68kDa -0.0057997
SYT17 synaptotagmin XVII -0.00579958
TBC1D9B TBC1 domain family, member 9B (with GRAM domain) -0.00579685
HYOU1 hypoxia up-regulated 1 -0.00579455
SYNE2 spectrin repeat containing, nuclear envelope 2 -0.0057812
TDO2 tryptophan 2,3-dioxygenase -0.00577797
DACH1 dachshund family transcription factor 1 -0.00575597
CFD complement factor D (adipsin) -0.00574902
DCPS decapping enzyme, scavenger -0.00574295
PDGFRA platelet-derived growth factor receptor, alpha polypeptide -0.00572512
AKR1C1 aldo-keto reductase family 1, member C1 -0.00571819
RALGDS ral guanine nucleotide dissociation stimulator -0.00570659
GATA2 GATA binding protein 2 -0.00569818
DLAT dihydrolipoamide S-acetyltransferase -0.00569195
VASH1 vasohibin 1 -0.00568729
TGFB3 transforming growth factor, beta 3 -0.00568479
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 -0.00567818
LIG1 ligase I, DNA, ATP-dependent -0.00565272
CALCA calcitonin-related polypeptide alpha -0.00564789
SFTPC surfactant protein C -0.00562529
PPP1R26 protein phosphatase 1, regulatory subunit 26 -0.0056214
OLFM1 olfactomedin 1 -0.00560052
CASP2 caspase 2, apoptosis-related cysteine peptidase -0.0055934
RAP1GAP RAP1 GTPase activating protein -0.0055893
PRRX1 paired related homeobox 1 -0.00556931
INSR insulin receptor -0.00556545
TCAF1 TRPM8 channel-associated factor 1 -0.00555772
PRC1 protein regulator of cytokinesis 1 -0.00554218
APLP2 amyloid beta (A4) precursor-like protein 2 -0.00553853
EXOSC10 exosome component 10 -0.00553838
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme -0.00553135
HNRNPM heterogeneous nuclear ribonucleoprotein M -0.00551559
CCDC88A coiled-coil domain containing 88A -0.0055131
TFF3 trefoil factor 3 (intestinal) -0.00550393
TMBIM6 transmembrane BAX inhibitor motif containing 6 -0.00549998
LAMB1 laminin, beta 1 -0.0054869
NTM neurotrimin -0.00548538
RBM25 RNA binding motif protein 25 -0.0054647
MAP3K5 mitogen-activated protein kinase kinase kinase 5 -0.00545575
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 -0.00545363
IGFBP2 insulin-like growth factor binding protein 2, 36kDa -0.00542378
PLXNA1 plexin A1 -0.0054194
WNT4 wingless-type MMTV integration site family, member 4 -0.00540322
STS steroid sulfatase (microsomal), isozyme S -0.00539648
CA2 carbonic anhydrase II -0.00539582
SCGB2A1 secretoglobin, family 2A, member 1 -0.00539343
SPRY2 sprouty homolog 2 (Drosophila) -0.00537084
SNX1 sorting nexin 1 -0.00531646
TUBGCP3 tubulin, gamma complex associated protein 3 -0.00531363
TIMELESS timeless circadian clock -0.00530807
FAM168A family with sequence similarity 168, member A -0.00530297
ESR1 estrogen receptor 1 -0.0053012
PDGFC platelet derived growth factor C -0.00527227
OBSL1 obscurin-like 1 -0.00526813
AMDHD2 amidohydrolase domain containing 2 -0.00526608
ACAD8 acyl-CoA dehydrogenase family, member 8 -0.00526475
MECOM MDS1 and EVI1 complex locus -0.00526074
LRP4 low density lipoprotein receptor-related protein 4 -0.0052595
GRAMD1B GRAM domain containing 1B -0.00525118
HACD3 3-hydroxyacyl-CoA dehydratase 3 -0.00523933
PSD3 pleckstrin and Sec7 domain containing 3 -0.00523559
SFPQ splicing factor proline/glutamine-rich -0.00523251
PFKL phosphofructokinase, liver -0.00523182
ANPEP alanyl (membrane) aminopeptidase -0.00522701
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1 -0.00522634
KANK2 KN motif and ankyrin repeat domains 2 -0.00521449
RBBP8 retinoblastoma binding protein 8 -0.00518871
ICMT isoprenylcysteine carboxyl methyltransferase -0.00517498
GSTM3 glutathione S-transferase mu 3 (brain) -0.00517447
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) -0.00516662
ADGRF5 adhesion G protein-coupled receptor F5 -0.00516498
GPHN gephyrin -0.00515763
TFF1 trefoil factor 1 -0.00513836
JAG2 jagged 2 -0.00511822
NAA40 N(alpha)-acetyltransferase 40, NatD catalytic subunit -0.00511603
SPAG5 sperm associated antigen 5 -0.0051102
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae) -0.00510905
GLO1 glyoxalase I -0.00510723
PPP1R14B protein phosphatase 1, regulatory (inhibitor) subunit 14B -0.00508728
PLXDC1 plexin domain containing 1 -0.0050856
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 -0.00508408
TBL1X transducin (beta)-like 1X-linked -0.00507883
CDC7 cell division cycle 7 -0.00507825
REEP1 receptor accessory protein 1 -0.00507272
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3 -0.005065
NOTCH2 notch 2 -0.00506405
CCNA2 cyclin A2 -0.00505377
LY6E lymphocyte antigen 6 complex, locus E -0.00505028
CD320 CD320 molecule -0.00504816
GPC3 glypican 3 -0.0050472
ANGPT2 angiopoietin 2 -0.00504404
GRK2 G protein-coupled receptor kinase 2 -0.00503992
KCNQ2 potassium channel, voltage gated KQT-like subfamily Q, member 2 -0.00502785
NUP85 nucleoporin 85kDa -0.00502418
CIT citron rho-interacting serine/threonine kinase -0.00502039
C7 complement component 7 -0.00501218
DMBT1 deleted in malignant brain tumors 1 -0.00499661
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -0.00499247
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 -0.0049923
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 -0.00499009
SIX1 SIX homeobox 1 -0.0049886
CENPE centromere protein E, 312kDa -0.00498485
P4HB prolyl 4-hydroxylase, beta polypeptide -0.00497601
RGS13 regulator of G-protein signaling 13 -0.00497568
MEIS1 Meis homeobox 1 -0.00497295
MELK maternal embryonic leucine zipper kinase -0.00494442
FBN2 fibrillin 2 -0.00493778
KIF18B kinesin family member 18B -0.00493763
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 -0.00493141
PDZD2 PDZ domain containing 2 -0.00491343
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked -0.00490998
DOCK10 dedicator of cytokinesis 10 -0.00490354
MSX1 msh homeobox 1 -0.00490262
LMNB1 lamin B1 -0.00489447
HEATR1 HEAT repeat containing 1 -0.00488646
SHMT1 serine hydroxymethyltransferase 1 (soluble) -0.00488545
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) -0.00488402
MTARC1 mitochondrial amidoxime reducing component 1 -0.00488316
KMT5A lysine methyltransferase 5A -0.00487927
AKT1 v-akt murine thymoma viral oncogene homolog 1 -0.00487786
MCM10 minichromosome maintenance complex component 10 -0.00486361
PRPH peripherin -0.00486064
CTSZ cathepsin Z -0.00485816
ACAT2 acetyl-CoA acetyltransferase 2 -0.00484934
SFRP4 secreted frizzled-related protein 4 -0.00484739
GAB2 GRB2-associated binding protein 2 -0.00484422
NDNF neuron-derived neurotrophic factor -0.00483736
TWIST1 twist family bHLH transcription factor 1 -0.00482931
RXRA retinoid X receptor, alpha -0.00482761
ARHGAP19 Rho GTPase activating protein 19 -0.00482231