BAFILOMYCIN-A1 Gene Set

Dataset LINCS L1000 CMAP Chemical Perturbation Consensus Signatures
Category transcriptomics
Type small molecule perturbation
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Genes

37 genes differentially expressed following the BAFILOMYCIN-A1 small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
INSIG1 insulin induced gene 1 10.0264
ALDOC aldolase C, fructose-bisphosphate 8.64477
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 5.49796
KDM3A lysine (K)-specific demethylase 3A 4.95705
MSMO1 methylsterol monooxygenase 1 4.81288
GAPDH glyceraldehyde-3-phosphate dehydrogenase 4.71826
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 4.65889
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 4.55596
FADS1 fatty acid desaturase 1 4.53069
DHCR7 7-dehydrocholesterol reductase 4.47095
SQLE squalene epoxidase 4.33874
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 4.25664
SCD stearoyl-CoA desaturase (delta-9-desaturase) 4.25642
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 4.24201
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1 4.17977
IDI1 isopentenyl-diphosphate delta isomerase 1 4.1101
FDPS farnesyl diphosphate synthase 4.03237
ACAT2 acetyl-CoA acetyltransferase 2 3.89567
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 3.86037
NSDHL NAD(P) dependent steroid dehydrogenase-like 3.76199
FDFT1 farnesyl-diphosphate farnesyltransferase 1 3.72199
SPP1 secreted phosphoprotein 1 3.70347
LDLR low density lipoprotein receptor 3.68127
PNPLA3 patatin-like phospholipase domain containing 3 3.65663
BHLHE40 basic helix-loop-helix family, member e40 3.64999
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 3.61838
RAPSN receptor-associated protein of the synapse 3.61799
PDK1 pyruvate dehydrogenase kinase, isozyme 1 3.57358
DHCR24 24-dehydrocholesterol reductase 3.53854
DUSP3 dual specificity phosphatase 3 3.5007
ERG28 ergosterol biosynthesis 28 homolog 3.355
MVD mevalonate (diphospho) decarboxylase 3.29309
LPIN1 lipin 1 3.23937
SREBF2 sterol regulatory element binding transcription factor 2 3.06071
HILPDA hypoxia inducible lipid droplet-associated 3.01019

decreased expression

Symbol Name Standardized Value
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 -3.29076
ADRB2 adrenoceptor beta 2, surface -3.03411