BAG1 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description BCL2-associated athanogene|The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. Multiple protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) initiation codon, and three alternative downstream AUG initiation codons. A related pseudogene has been defined on chromosome X. [provided by RefSeq, Feb 2010] (NCBI Entrez Gene Database, 573)
Similar Terms
Downloads & Tools

Genes

346 genes differentially expressed following the BAG1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
PRSS55 protease, serine, 55 3.05604
PRR35 proline rich 35 3.05604
COL17A1 collagen, type XVII, alpha 1 3.05604
GZMM granzyme M (lymphocyte met-ase 1) 3.05604
ADGRG1 adhesion G protein-coupled receptor G1 3.05604
DMRTC1B DMRT-like family C1B 3.05604
ABCA10 ATP-binding cassette, sub-family A (ABC1), member 10 3.05604
CNTNAP4 contactin associated protein-like 4 3.05604
ERICH6B glutamate-rich 6B 3.05604
ZNF467 zinc finger protein 467 3.05604
ZNF98 zinc finger protein 98 3.05604
HCRT hypocretin (orexin) neuropeptide precursor 3.05604
MGAM2 maltase-glucoamylase 2 (putative) 3.05604
PMP2 peripheral myelin protein 2 3.05604
PABPC1L2B poly(A) binding protein, cytoplasmic 1-like 2B 3.05604
PKD2L1 polycystic kidney disease 2-like 1 3.05604
MYOCOS myocilin opposite strand 3.05604
GALNTL5 polypeptide N-acetylgalactosaminyltransferase-like 5 3.05604
ZNF703 zinc finger protein 703 3.05604
ATOH1 atonal homolog 1 (Drosophila) 3.05604
HRG histidine-rich glycoprotein 3.05604
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy 3.05604
SLC10A6 solute carrier family 10 (sodium/bile acid cotransporter), member 6 3.05322
TPRX1 tetra-peptide repeat homeobox 1 3.05322
CASP4 caspase 4, apoptosis-related cysteine peptidase 3.05322
PDZD9 PDZ domain containing 9 3.05322
SOX14 SRY (sex determining region Y)-box 14 3.05322
SLC35G6 solute carrier family 35, member G6 3.05322
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1 3.05322
FXYD4 FXYD domain containing ion transport regulator 4 3.05322
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A 3.05322
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) 3.05322
ARL5C ADP-ribosylation factor-like 5C 3.05322
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 3.05322
EVPL envoplakin 3.05322
IGFN1 immunoglobulin-like and fibronectin type III domain containing 1 3.05322
NMUR1 neuromedin U receptor 1 3.05322
GJB4 gap junction protein, beta 4, 30.3kDa 3.05322
CD68 CD68 molecule 3.05322
TMEM72 transmembrane protein 72 3.05322
TMPRSS3 transmembrane protease, serine 3 3.05322
SLC9C2 solute carrier family 9, member C2 (putative) 3.05322
NPIPA8 nuclear pore complex interacting protein family, member A8 3.05322
SLC39A5 solute carrier family 39 (zinc transporter), member 5 3.05322
LBX2 ladybird homeobox 2 3.05322
PECAM1 platelet/endothelial cell adhesion molecule 1 3.05322
SHCBP1L SHC SH2-domain binding protein 1-like 3.05322
PBOV1 prostate and breast cancer overexpressed 1 3.05322
TAS2R8 taste receptor, type 2, member 8 3.05322
OXT oxytocin/neurophysin I prepropeptide 3.05322
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4 3.05322
ASB10 ankyrin repeat and SOCS box containing 10 3.05322
OLIG2 oligodendrocyte lineage transcription factor 2 3.05322
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa 3.05322
LRRC56 leucine rich repeat containing 56 3.05322
ACVRL1 activin A receptor type II-like 1 3.05322
CEMP1 cementum protein 1 3.05322
SPATA31G1 SPATA31 subfamily G member 1 3.05322
SMLR1 small leucine-rich protein 1 3.05322
HR hair growth associated 3.05322
SDR16C5 short chain dehydrogenase/reductase family 16C, member 5 3.05322
DYNAP dynactin associated protein 3.05322
ROPN1 rhophilin associated tail protein 1 3.05322
SAA4 serum amyloid A4, constitutive 3.05322
UTS2 urotensin 2 3.05322
SLAMF1 signaling lymphocytic activation molecule family member 1 3.05322
DNAAF1 dynein, axonemal, assembly factor 1 3.05322
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 3.05322
CPHXL2 cytoplasmic polyadenylated homeobox like 2 3.05322
CIMIP2B ciliary microtubule inner protein 2B 3.05322
CIMIP2C ciliary microtubule inner protein 2C 3.05322
CIMIP7 ciliary microtubule inner protein 7 3.05322
MYMK myomaker, myoblast fusion factor 3.05322
CLEC20A C-type lectin domain containing 20A 3.05322
SPATA46 spermatogenesis associated 46 3.05322
CALHM5 calcium homeostasis modulator family member 5 3.05322
TMEM271 transmembrane protein 271 3.05322
SLAMF6 SLAM family member 6 3.05322
PDE1B phosphodiesterase 1B, calmodulin-dependent 3.05322
USH1G Usher syndrome 1G (autosomal recessive) 3.05322
SLC22A11 solute carrier family 22 (organic anion/urate transporter), member 11 3.05322
OR6T1 olfactory receptor, family 6, subfamily T, member 1 3.05322
COXFA4L2 cytochrome c oxidase hypoxia associated subunit FA4L2 3.05322
TAS2R5 taste receptor, type 2, member 5 3.05322
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 3.05322
GJA3 gap junction protein, alpha 3, 46kDa 3.05322
ZACN zinc activated ligand-gated ion channel 3.05322
LIPK lipase, family member K 3.05322
LIPJ lipase, family member J 3.05322
SECTM1 secreted and transmembrane 1 3.05322
SCRT1 scratch family zinc finger 1 3.05322
C3ORF80 chromosome 3 open reading frame 80 3.05322
VSX2 visual system homeobox 2 3.05322
EDAR ectodysplasin A receptor 3.05322
CLDN2 claudin 2 3.05322
CFAP99 cilia and flagella associated protein 99 3.05322
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 3.05322
PCDHA7 protocadherin alpha 7 3.05322
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B 3.05322
SLC36A3 solute carrier family 36, member 3 3.05322
MEFV Mediterranean fever 3.05322
C16ORF78 chromosome 16 open reading frame 78 3.05322
SLC32A1 solute carrier family 32 (GABA vesicular transporter), member 1 3.05322
KLF2 Kruppel-like factor 2 3.05322
HHATL hedgehog acyltransferase-like 3.05322
NXNL1 nucleoredoxin-like 1 3.05322
EDN3 endothelin 3 3.05322
ESAM endothelial cell adhesion molecule 3.05322
TCF21 transcription factor 21 3.05322
PDCD1 programmed cell death 1 3.05322
AGR2 anterior gradient 2 3.05322
TECRL trans-2,3-enoyl-CoA reductase-like 3.05322
NUTM2B NUT family member 2B 3.05322
SP100 SP100 nuclear antigen 3.05322
PSORS1C1 psoriasis susceptibility 1 candidate 1 3.05322
GH2 growth hormone 2 3.05322
OR56B1 olfactory receptor, family 56, subfamily B, member 1 3.05322
MAB21L3 mab-21-like 3 (C. elegans) 3.05322
TBXA2R thromboxane A2 receptor 3.05322
RSPH10B radial spoke head 10 homolog B (Chlamydomonas) 3.05322
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) 3.05322
LRRN4 leucine rich repeat neuronal 4 3.05322
LMX1A LIM homeobox transcription factor 1, alpha 3.05322
RSRC2 arginine/serine-rich coiled-coil 2 3.05322
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5 3.05322
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 3.05322
DCT dopachrome tautomerase 3.05322
GPR62 G protein-coupled receptor 62 3.05322
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 3.05322
IL9R interleukin 9 receptor 3.05322
SAMD5 sterile alpha motif domain containing 5 3.05322
CFAP47 cilia and flagella associated protein 47 3.05322
ASTL astacin-like metallo-endopeptidase (M12 family) 3.05322
KISS1 KiSS-1 metastasis-suppressor 3.05322
VWA3B von Willebrand factor A domain containing 3B 3.05322
CCL15 chemokine (C-C motif) ligand 15 3.05322
AGXT2 alanine--glyoxylate aminotransferase 2 3.05322
WFDC10A WAP four-disulfide core domain 10A 3.05322
TGM6 transglutaminase 6 3.05322
ICAM2 intercellular adhesion molecule 2 3.05322
IL37 interleukin 37 3.05322
PARP15 poly (ADP-ribose) polymerase family, member 15 3.05322
MSLN mesothelin 3.05322
CHIA chitinase, acidic 3.05322
PPP1R3A protein phosphatase 1, regulatory subunit 3A 3.05322
TMEM156 transmembrane protein 156 3.05322
ZPLD1 zona pellucida-like domain containing 1 3.05322
TMPRSS15 transmembrane protease, serine 15 3.05322
IFNK interferon, kappa 3.05322
GCM1 glial cells missing homolog 1 (Drosophila) 3.05322
PITX3 paired-like homeodomain 3 3.05322
SDSL serine dehydratase-like 3.05322
APOL3 apolipoprotein L, 3 3.05322
CD3D CD3d molecule, delta (CD3-TCR complex) 3.05322
ANKRD30B ankyrin repeat domain 30B 3.05322
C10ORF95 chromosome 10 open reading frame 95 3.05322
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 2.99834
SERINC1 serine incorporator 1 2.92527
MRPL58 mitochondrial ribosomal protein L58 2.88505
RBM43 RNA binding motif protein 43 2.88505
ZNF24 zinc finger protein 24 2.76734
TMEM232 transmembrane protein 232 2.75216
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 2.69822
ACOT8 acyl-CoA thioesterase 8 2.6684
PATJ PATJ crumbs cell polarity complex component 2.64899
VEZF1 vascular endothelial zinc finger 1 2.58544
AFAP1 actin filament associated protein 1 2.55974
LOXL2 lysyl oxidase-like 2 2.55924
DRC7 dynein regulatory complex subunit 7 2.50218
CDHR5 cadherin-related family member 5 2.48244
LRRD1 leucine-rich repeats and death domain containing 1 2.48244
SLC5A7 solute carrier family 5 (sodium/choline cotransporter), member 7 2.48244
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 2.47797
F2RL1 coagulation factor II (thrombin) receptor-like 1 2.47691
C8ORF33 chromosome 8 open reading frame 33 2.46502
ZDHHC8 zinc finger, DHHC-type containing 8 2.46141
URM1 ubiquitin related modifier 1 2.45143
MLEC malectin 2.43901
MT1E metallothionein 1E 2.42218
ADK adenosine kinase 2.41927
ABAT 4-aminobutyrate aminotransferase 2.41927
SETD4 SET domain containing 4 2.41202
CEP170B centrosomal protein 170B 2.38974
UQCC2 ubiquinol-cytochrome c reductase complex assembly factor 2 2.36781
RPA4 replication protein A4, 30kDa 2.36227
GPHA2 glycoprotein hormone alpha 2 2.33236
ARHGAP4 Rho GTPase activating protein 4 2.31523
ECT2L epithelial cell transforming 2 like 2.31523
SRGN serglycin 2.27184
RPS18 ribosomal protein S18 2.23961
PRADC1 protease-associated domain containing 1 2.23961
TBL1X transducin (beta)-like 1X-linked 2.23885
CFAP92 cilia and flagella associated protein 92 (putative) 2.23775
GTPBP2 GTP binding protein 2 2.23249
EPS8L2 EPS8-like 2 2.22195
RPL39 ribosomal protein L39 2.21679
BLVRA biliverdin reductase A 2.20387
CS citrate synthase 2.20076
SERF1A small EDRK-rich factor 1A (telomeric) 2.1902
SLC23A3 solute carrier family 23, member 3 2.1902
RUFY4 RUN and FYVE domain containing 4 2.1902
MIS18A MIS18 kinetochore protein A 2.1902
GPR146 G protein-coupled receptor 146 2.1902
LCP1 lymphocyte cytosolic protein 1 (L-plastin) 2.1902
PTH2 parathyroid hormone 2 2.1902
THSD1 thrombospondin, type I, domain containing 1 2.1902
RTBDN retbindin 2.1902
OTOG otogelin 2.17558
RTL6 retrotransposon Gag like 6 2.17558
CHIC2 cysteine-rich hydrophobic domain 2 2.17558
SSPN sarcospan 2.16687
PDE4C phosphodiesterase 4C, cAMP-specific 2.16687
MT1H metallothionein 1H 2.15691
MT1G metallothionein 1G 2.14552
MAPK3 mitogen-activated protein kinase 3 2.14552
TMEM19 transmembrane protein 19 2.14552
GSN gelsolin 2.14552
RPL38 ribosomal protein L38 2.14496
GATAD1 GATA zinc finger domain containing 1 2.13097
FZD2 frizzled class receptor 2 2.12962
CCDC61 coiled-coil domain containing 61 2.11035
PRCC papillary renal cell carcinoma (translocation-associated) 2.10483
OTOGL otogelin-like 2.1003
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha 2.1003
PIGK phosphatidylinositol glycan anchor biosynthesis, class K 2.09819
IQANK1 IQ motif and ankyrin repeat containing 1 2.09175
ZNF879 zinc finger protein 879 2.0701
TMEM17 transmembrane protein 17 2.05901
RPLP1 ribosomal protein, large, P1 2.05901
ALG8 ALG8, alpha-1,3-glucosyltransferase 2.05561
HVCN1 hydrogen voltage gated channel 1 2.05228
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 2.05162
DRC4 dynein regulatory complex subunit 4 2.03933
PAIP1 poly(A) binding protein interacting protein 1 2.03933
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 2.03933
SLC25A39 solute carrier family 25, member 39 2.03721
CA10 carbonic anhydrase X 2.03106
TSPAN17 tetraspanin 17 2.02379
ZBTB26 zinc finger and BTB domain containing 26 2.01645
VMA12 vacuolar ATPase assembly factor VMA12 2.01645
TMA7 translation machinery associated 7 homolog (S. cerevisiae) 2.01563
TGIF2 TGFB-induced factor homeobox 2 2.01465
ATG3 autophagy related 3 2.01282
CCDC32 coiled-coil domain containing 32 2.01282
RPL35 ribosomal protein L35 2.01029
RNF115 ring finger protein 115 2.01029

decreased expression

Symbol Name Standardized Value
RCN2 reticulocalbin 2, EF-hand calcium binding domain -3.05322
LOC112694756 uncharaterized LOC112694756 -3.05322
POLR1G RNA polymerase I subunit G -3.05322
TFF3 trefoil factor 3 (intestinal) -3.05322
SLA Src-like-adaptor -3.05322
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1 -3.04564
COPS7A COP9 signalosome subunit 7A -3.02434
SNX17 sorting nexin 17 -3.01402
GCKR glucokinase (hexokinase 4) regulator -2.92527
RASSF6 Ras association (RalGDS/AF-6) domain family member 6 -2.92527
RIMBP2 RIMS binding protein 2 -2.92527
CSNK2A3 casein kinase 2, alpha 3 polypeptide -2.92527
SMIM45 small integral membrane protein 45 -2.92527
KIF19 kinesin family member 19 -2.92527
OR2AG1 olfactory receptor, family 2, subfamily AG, member 1 (gene/pseudogene) -2.92527
ANKRD33 ankyrin repeat domain 33 -2.92527
HCRTR1 hypocretin (orexin) receptor 1 -2.92527
TBX20 T-box 20 -2.92527
CLDN5 claudin 5 -2.92527
GOLGA6L7 golgin A6 family like 7 -2.92527
SPATS1 spermatogenesis associated, serine-rich 1 -2.92527
CES4A carboxylesterase 4A -2.92527
UNC93A unc-93 homolog A (C. elegans) -2.92527
DUSP9 dual specificity phosphatase 9 -2.92527
USP40 ubiquitin specific peptidase 40 -2.92527
IMPG1 interphotoreceptor matrix proteoglycan 1 -2.92527
UGT2B7 UDP glucuronosyltransferase 2 family, polypeptide B7 -2.92527
TBX10 T-box 10 -2.92527
ZIC4 Zic family member 4 -2.92527
TNFRSF19 tumor necrosis factor receptor superfamily, member 19 -2.92527
BAG1 BCL2-associated athanogene -2.92527
STAB1 stabilin 1 -2.92527
ABCG8 ATP-binding cassette, sub-family G (WHITE), member 8 -2.92527
CFB complement factor B -2.92527
PCDHGB2 protocadherin gamma subfamily B, 2 -2.92527
CCDC154 coiled-coil domain containing 154 -2.92527
ALX4 ALX homeobox 4 -2.92527
RSPH10B2 radial spoke head 10 homolog B2 (Chlamydomonas) -2.92527
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 -2.92527
HMGB4 high mobility group box 4 -2.92527
CCNI2 cyclin I family, member 2 -2.92527
UBFD1 ubiquitin family domain containing 1 -2.89442
CYSRT1 cysteine-rich tail protein 1 -2.84354
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 -2.81141
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 -2.81141
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11 -2.81141
SAPCD1 suppressor APC domain containing 1 -2.81141
PRSS27 protease, serine 27 -2.70596
SHROOM1 shroom family member 1 -2.6684
U2SURP U2 snRNP-associated SURP domain containing -2.64639
TUBGCP3 tubulin, gamma complex associated protein 3 -2.62374
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 -2.59373
TNS1 tensin 1 -2.5279
MTAP methylthioadenosine phosphorylase -2.48453
ZNF678 zinc finger protein 678 -2.48244
ZNF385B zinc finger protein 385B -2.4652
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 -2.45475
MLIP muscular LMNA-interacting protein -2.45143
LRRC66 leucine rich repeat containing 66 -2.45143
SCNN1D sodium channel, non voltage gated 1 delta subunit -2.45143
ARRDC4 arrestin domain containing 4 -2.45098
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) -2.42871
FAM111A family with sequence similarity 111, member A -2.40469
SLC26A3 solute carrier family 26 (anion exchanger), member 3 -2.33128
KCTD2 potassium channel tetramerization domain containing 2 -2.31523
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 -2.2934
SARNP SAP domain containing ribonucleoprotein -2.28719
PRTN3 proteinase 3 -2.28305
MICALL2 MICAL-like 2 -2.25416
HCLS1 hematopoietic cell-specific Lyn substrate 1 -2.24325
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled -2.24325
B4GALT7 xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7 -2.21556
RAG1 recombination activating gene 1 -2.20743
TMEM8B transmembrane protein 8B -2.20202
H2AX H2A.X variant histone -2.1902
EPCAM epithelial cell adhesion molecule -2.1902
EIF4E2 eukaryotic translation initiation factor 4E family member 2 -2.1902
KCNMB4 potassium channel subfamily M regulatory beta subunit 4 -2.1902
SPIN2A spindlin family, member 2A -2.17373
PCDHB16 protocadherin beta 16 -2.17331
C3 complement component 3 -2.16687
NAA40 N(alpha)-acetyltransferase 40, NatD catalytic subunit -2.15691
FHL2 four and a half LIM domains 2 -2.15348
FBXL22 F-box and leucine-rich repeat protein 22 -2.14552
ATP8B4 ATPase, class I, type 8B, member 4 -2.14552
SV2C synaptic vesicle glycoprotein 2C -2.14552
DUSP10 dual specificity phosphatase 10 -2.14552
TMEM233 transmembrane protein 233 -2.14552
CHMP5 charged multivesicular body protein 5 -2.13325
WEE1 WEE1 G2 checkpoint kinase -2.13175
GPAM glycerol-3-phosphate acyltransferase, mitochondrial -2.13097
MRPL12 mitochondrial ribosomal protein L12 -2.11632
CES2 carboxylesterase 2 -2.1003
ANXA5 annexin A5 -2.08538
SEC23IP SEC23 interacting protein -2.07016
CEP120 centrosomal protein 120kDa -2.05228
TUNAR TCL1 upstream neural differentiation-associated RNA -2.04965
SLC38A5 solute carrier family 38, member 5 -2.04704
MACO1 macoilin 1 -2.03721
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 -2.03581