BAG2 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description BCL2-associated athanogene 2|BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 9532)
External Link https://ncbi.nlm.nih.gov/gene/9532
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Genes

499 genes differentially expressed following the BAG2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
MAP7 microtubule-associated protein 7 0.0179824
IPO13 importin 13 0.0152648
RPS4Y1 ribosomal protein S4, Y-linked 1 0.0147166
PLAAT3 phospholipase A and acyltransferase 3 0.0131316
ADO 2-aminoethanethiol (cysteamine) dioxygenase 0.0124503
P3H2 prolyl 3-hydroxylase 2 0.0121877
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 0.0115489
HOXC6 homeobox C6 0.0113224
PTPRE protein tyrosine phosphatase, receptor type, E 0.0113029
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.0110725
TFF3 trefoil factor 3 (intestinal) 0.0108319
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 0.0105516
NID2 nidogen 2 (osteonidogen) 0.0105027
PTP4A2 protein tyrosine phosphatase type IVA, member 2 0.0103483
CTBP2 C-terminal binding protein 2 0.0100674
COMP cartilage oligomeric matrix protein 0.010013
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 0.00996051
EIF5A eukaryotic translation initiation factor 5A 0.0097825
SPINK1 serine peptidase inhibitor, Kazal type 1 0.00956686
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 0.00936832
CALCA calcitonin-related polypeptide alpha 0.00933284
DDAH1 dimethylarginine dimethylaminohydrolase 1 0.00923901
TXLNA taxilin alpha 0.00916183
AMIGO2 adhesion molecule with Ig-like domain 2 0.00909854
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 0.00907947
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) 0.00895606
CASP2 caspase 2, apoptosis-related cysteine peptidase 0.00861291
ZNF160 zinc finger protein 160 0.00855831
SFRP4 secreted frizzled-related protein 4 0.00852063
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 0.00851312
ZNF721 zinc finger protein 721 0.00849798
TFF1 trefoil factor 1 0.00848087
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 0.00839807
SHB Src homology 2 domain containing adaptor protein B 0.00838684
LMNB2 lamin B2 0.00834509
FBP1 fructose-1,6-bisphosphatase 1 0.00830997
LYN LYN proto-oncogene, Src family tyrosine kinase 0.00830393
HAUS2 HAUS augmin-like complex, subunit 2 0.008196
CGA glycoprotein hormones, alpha polypeptide 0.00812764
NTS neurotensin 0.00811597
FA2H fatty acid 2-hydroxylase 0.00809817
WASHC4 WASH complex subunit 4 0.00798848
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 0.00796893
CRIP1 cysteine-rich protein 1 (intestinal) 0.00795843
CRLF1 cytokine receptor-like factor 1 0.00794919
FBN2 fibrillin 2 0.00791118
KDM5D lysine (K)-specific demethylase 5D 0.00790717
OLFM1 olfactomedin 1 0.007891
H2AFV H2A histone family, member V 0.00787313
BCAT2 branched chain amino-acid transaminase 2, mitochondrial 0.00766567
SFPQ splicing factor proline/glutamine-rich 0.00766527
LGALS4 lectin, galactoside-binding, soluble, 4 0.00763254
IRX5 iroquois homeobox 5 0.00760203
NOTCH2NL notch 2 N-terminal like 0.0075886
ZBTB20 zinc finger and BTB domain containing 20 0.00758425
NPTX2 neuronal pentraxin II 0.00752517
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 0.00751582
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 0.00750749
SLC17A3 solute carrier family 17 (organic anion transporter), member 3 0.00749159
CNPY3 canopy FGF signaling regulator 3 0.00748659
GUSB glucuronidase, beta 0.00745679
FBXW12 F-box and WD repeat domain containing 12 0.00742576
VNN1 vanin 1 0.00739888
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor 0.00738859
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21 0.0073863
ESR1 estrogen receptor 1 0.00736426
NDRG1 N-myc downstream regulated 1 0.00731949
HELLS helicase, lymphoid-specific 0.00730163
TTC39A tetratricopeptide repeat domain 39A 0.00729077
LEFTY1 left-right determination factor 1 0.00728804
IGFBP6 insulin-like growth factor binding protein 6 0.00718822
SPINK4 serine peptidase inhibitor, Kazal type 4 0.00716718
PRR11 proline rich 11 0.00715807
COL10A1 collagen, type X, alpha 1 0.0071495
DTX4 deltex 4, E3 ubiquitin ligase 0.00712825
HIP1 huntingtin interacting protein 1 0.00706677
TFF2 trefoil factor 2 0.00704948
GATA6 GATA binding protein 6 0.00703132
CD1E CD1e molecule 0.00702594
ASRGL1 asparaginase like 1 0.00700223
ARTN artemin 0.00698214
ADGRG6 adhesion G protein-coupled receptor G6 0.006973
ACAT2 acetyl-CoA acetyltransferase 2 0.00694936
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 0.00694835
DKFZP586I1420 uncharacterized protein DKFZp586I1420 0.00692644
PXDN peroxidasin 0.00686088
LPCAT1 lysophosphatidylcholine acyltransferase 1 0.00684548
USH1C Usher syndrome 1C (autosomal recessive, severe) 0.00683912
ANXA10 annexin A10 0.00681448
GAL galanin/GMAP prepropeptide 0.00679325
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.00672267
MBL2 mannose-binding lectin (protein C) 2, soluble 0.00671336
LARS1 leucyl-tRNA synthetase 1 0.00668512
KIAA0930 KIAA0930 0.00667413
STK39 serine threonine kinase 39 0.00667325
PDIA4 protein disulfide isomerase family A, member 4 0.00666402
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15 0.00665775
PKP2 plakophilin 2 0.00665384
KRT8 keratin 8, type II 0.00663283
GRAMD4 GRAM domain containing 4 0.0066277
AGR2 anterior gradient 2 0.00661383
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) 0.00656875
MAPT microtubule-associated protein tau 0.00656274
INSR insulin receptor 0.006535
MUC2 mucin 2, oligomeric mucus/gel-forming 0.00651053
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 0.00649859
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 0.00648713
TMBIM6 transmembrane BAX inhibitor motif containing 6 0.00645456
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 0.006449
EZR ezrin 0.00643795
EFHD2 EF-hand domain family, member D2 0.0064309
GLA galactosidase, alpha 0.00642374
S100A4 S100 calcium binding protein A4 0.00642291
SGK1 serum/glucocorticoid regulated kinase 1 0.00639789
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 0.00638259
SPATA20 spermatogenesis associated 20 0.00638181
MUC4 mucin 4, cell surface associated 0.00637326
FADS1 fatty acid desaturase 1 0.00636464
MBOAT7 membrane bound O-acyltransferase domain containing 7 0.00634227
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) 0.00633359
KCNK12 potassium channel, two pore domain subfamily K, member 12 0.00632362
CYBA cytochrome b-245, alpha polypeptide 0.00631975
TUBGCP3 tubulin, gamma complex associated protein 3 0.0063129
RETREG1 reticulophagy regulator 1 0.00626807
NVL nuclear VCP-like 0.00623819
TMBIM4 transmembrane BAX inhibitor motif containing 4 0.0062368
CDCA4 cell division cycle associated 4 0.00622983
TPSAB1 tryptase alpha/beta 1 0.00621967
VPREB3 pre-B lymphocyte 3 0.00618986
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 0.00618354
BPIFA1 BPI fold containing family A, member 1 0.00617189
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 0.00616562
AXL AXL receptor tyrosine kinase 0.00614246
SEPTIN10 septin 10 0.00613328
DPYSL2 dihydropyrimidinase-like 2 0.00612747
SYNJ2 synaptojanin 2 0.00612155
MTCL1 microtubule crosslinking factor 1 0.00612044
TMEM63A transmembrane protein 63A 0.00609966
ZNF611 zinc finger protein 611 0.00607811
CCP110 centriolar coiled coil protein 110kDa 0.0060631
ISYNA1 inositol-3-phosphate synthase 1 0.00605514
LRP2 low density lipoprotein receptor-related protein 2 0.00605144
TBXAS1 thromboxane A synthase 1 (platelet) 0.00604555
DUOX2 dual oxidase 2 0.00603135
PHACTR2 phosphatase and actin regulator 2 0.00602776
PDZD8 PDZ domain containing 8 0.00601355
RABEP2 rabaptin, RAB GTPase binding effector protein 2 0.00599071
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) 0.00596945
TERF1 telomeric repeat binding factor (NIMA-interacting) 1 0.00596737
SIVA1 SIVA1, apoptosis-inducing factor 0.00596495
CD320 CD320 molecule 0.00596021
BLNK B-cell linker 0.0059461
MMP15 matrix metallopeptidase 15 (membrane-inserted) 0.00593709
PLLP plasmolipin 0.00591544
DACT1 dishevelled-binding antagonist of beta-catenin 1 0.00591397
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4 0.00590426
ARHGAP22 Rho GTPase activating protein 22 0.00590085
SPINT2 serine peptidase inhibitor, Kunitz type, 2 0.00588765
SLC38A1 solute carrier family 38, member 1 0.00587924
TST thiosulfate sulfurtransferase (rhodanese) 0.00583084
KIAA0319L KIAA0319-like 0.0058191
PTPRD protein tyrosine phosphatase, receptor type, D 0.00580413
MOCOS molybdenum cofactor sulfurase 0.00579678
DNMT1 DNA (cytosine-5-)-methyltransferase 1 0.00578058
CIT citron rho-interacting serine/threonine kinase 0.00577524
CASP6 caspase 6, apoptosis-related cysteine peptidase 0.00576823
MSANTD2 Myb/SANT-like DNA-binding domain containing 2 0.00576496
RAP1GAP2 RAP1 GTPase activating protein 2 0.00576229
BUB3 BUB3 mitotic checkpoint protein 0.00576093
SHMT1 serine hydroxymethyltransferase 1 (soluble) 0.00575632
CD1B CD1b molecule 0.00575048
NPIPB3 nuclear pore complex interacting protein family, member B3 0.00573425
DHFR dihydrofolate reductase 0.00572734
NEFH neurofilament, heavy polypeptide 0.00571925
LITAF lipopolysaccharide-induced TNF factor 0.00570896
ELAC2 elaC ribonuclease Z 2 0.00570665
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 0.00570184
LUC7L3 LUC7-like 3 (S. cerevisiae) 0.00569515
STS steroid sulfatase (microsomal), isozyme S 0.00568619
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) 0.00568328
VWA1 von Willebrand factor A domain containing 1 0.00568305
DPP4 dipeptidyl-peptidase 4 0.00568059
HNRNPL heterogeneous nuclear ribonucleoprotein L 0.00566736
CA9 carbonic anhydrase IX 0.00566399
IPO9 importin 9 0.00563175
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.00560878
CPM carboxypeptidase M 0.00560141
GGTLC1 gamma-glutamyltransferase light chain 1 0.00558771
DPY19L1 dpy-19-like 1 (C. elegans) 0.00556562
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15 0.00555588
BAD BCL2-associated agonist of cell death 0.00554822
TRA2A transformer 2 alpha homolog (Drosophila) 0.00553914
FST follistatin 0.00552802
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) 0.00552383
SNRPE small nuclear ribonucleoprotein polypeptide E 0.00551271
CALCB calcitonin-related polypeptide beta 0.00550183
CBX5 chromobox homolog 5 0.00549888
SPRY2 sprouty homolog 2 (Drosophila) 0.00546475
ADCY1 adenylate cyclase 1 (brain) 0.00545312
HYI hydroxypyruvate isomerase (putative) 0.00545088
RAB20 RAB20, member RAS oncogene family 0.00542326
NUP107 nucleoporin 107kDa 0.00540933
CPB1 carboxypeptidase B1 (tissue) 0.00540917
SPATA7 spermatogenesis associated 7 0.00539116
GTSE1 G-2 and S-phase expressed 1 0.00538199
LPAR1 lysophosphatidic acid receptor 1 0.00537781
TARDBP TAR DNA binding protein 0.00537748
HOXB6 homeobox B6 0.00537151
RNH1 ribonuclease/angiogenin inhibitor 1 0.00537081
FBXO11 F-box protein 11 0.0053684
HBS1L HBS1-like translational GTPase 0.00536517
PYGL phosphorylase, glycogen, liver 0.00536391
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila) 0.00535884
MYBPC2 myosin binding protein C, fast type 0.0053328
GUCY2C guanylate cyclase 2C 0.00532371
BCL2 B-cell CLL/lymphoma 2 0.00531728
HK2 hexokinase 2 0.00530831
HOXA5 homeobox A5 0.00530606
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6 0.00530388
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) 0.00530302
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 0.00530272
HDAC1 histone deacetylase 1 0.00529816
CHEK2 checkpoint kinase 2 0.00529814
APOC1 apolipoprotein C-I 0.00529376
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.00528301
MOAP1 modulator of apoptosis 1 0.00527479
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1 0.0052726
TG thyroglobulin 0.00526873
FAM149A family with sequence similarity 149, member A 0.00526796
NRXN2 neurexin 2 0.00526684
CCDC68 coiled-coil domain containing 68 0.00525373
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) 0.00525267
SPRY4 sprouty homolog 4 (Drosophila) 0.00524651
RNF128 ring finger protein 128, E3 ubiquitin protein ligase 0.00521336
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) 0.00521039
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3 0.0052099
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.00520543
KIF1A kinesin family member 1A 0.00520354
RAD21 RAD21 homolog (S. pombe) 0.00519763
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1) 0.00518261
HYOU1 hypoxia up-regulated 1 0.00518049
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha 0.00517977
CSNK1E casein kinase 1, epsilon 0.00517857
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1 0.00517611
RGS5 regulator of G-protein signaling 5 0.00516568
WSB1 WD repeat and SOCS box containing 1 0.00515957
GTPBP8 GTP-binding protein 8 (putative) 0.00514822
RAB25 RAB25, member RAS oncogene family 0.0051314
GAL3ST1 galactose-3-O-sulfotransferase 1 0.00513094
FAIM Fas apoptotic inhibitory molecule 0.00512349

decreased expression

Symbol Name Standardized Value
S100A9 S100 calcium binding protein A9 -0.0200576
MAGEA3 melanoma antigen family A3 -0.0172437
IFI27 interferon, alpha-inducible protein 27 -0.0161082
XIC X chromosome inactivation center -0.0156668
TUBB2A tubulin, beta 2A class IIa -0.0154441
KRT14 keratin 14, type I -0.0150939
HSPB1 heat shock 27kDa protein 1 -0.0148492
LTF lactotransferrin -0.0141369
S100A8 S100 calcium binding protein A8 -0.0141113
CXCL10 chemokine (C-X-C motif) ligand 10 -0.0138125
XPO7 exportin 7 -0.0133591
GNAS GNAS complex locus -0.0130853
ATF3 activating transcription factor 3 -0.0130836
RNF167 ring finger protein 167 -0.012945
KRT5 keratin 5, type II -0.012804
IFI44L interferon-induced protein 44-like -0.0112252
IFI44 interferon-induced protein 44 -0.0111643
KRT15 keratin 15, type I -0.011111
CXCL13 chemokine (C-X-C motif) ligand 13 -0.0110935
MAGEA12 melanoma antigen family A12 -0.0110648
GPNMB glycoprotein (transmembrane) nmb -0.0108332
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 -0.0104543
HIST1H2AC histone cluster 1, H2ac -0.010429
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 -0.0104071
S100A7 S100 calcium binding protein A7 -0.0103991
CD59 CD59 molecule, complement regulatory protein -0.0103013
DSP desmoplakin -0.010204
LAMP3 lysosomal-associated membrane protein 3 -0.010165
RCAN1 regulator of calcineurin 1 -0.0101648
S100A14 S100 calcium binding protein A14 -0.0101255
IQCG IQ motif containing G -0.0100645
DEFB1 defensin, beta 1 -0.00980692
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) -0.00974574
BAMBI BMP and activin membrane-bound inhibitor -0.00974058
TSC22D1 TSC22 domain family, member 1 -0.00964232
KRT17 keratin 17, type I -0.00958584
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 -0.00951841
TSPAN7 tetraspanin 7 -0.00951227
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 -0.00945154
GRB7 growth factor receptor-bound protein 7 -0.00944463
GPM6B glycoprotein M6B -0.00943432
LYPD3 LY6/PLAUR domain containing 3 -0.00937117
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 -0.00931762
FXYD3 FXYD domain containing ion transport regulator 3 -0.00929944
TM4SF1 transmembrane 4 L six family member 1 -0.00927203
C1QA complement component 1, q subcomponent, A chain -0.00919022
QPRT quinolinate phosphoribosyltransferase -0.00917131
TMOD1 tropomodulin 1 -0.00914054
SLPI secretory leukocyte peptidase inhibitor -0.00911345
BTN3A3 butyrophilin, subfamily 3, member A3 -0.00910285
GEM GTP binding protein overexpressed in skeletal muscle -0.00904092
ATXN1 ataxin 1 -0.00901434
CLCA2 chloride channel accessory 2 -0.00894397
DAXX death-domain associated protein -0.00885778
FGF13 fibroblast growth factor 13 -0.00884182
WIPI1 WD repeat domain, phosphoinositide interacting 1 -0.00875373
CXCL11 chemokine (C-X-C motif) ligand 11 -0.00874398
MAGEA1 melanoma antigen family A1 -0.00872811
ISG15 ISG15 ubiquitin-like modifier -0.00864128
AREG amphiregulin -0.00863028
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) -0.00855132
FABP4 fatty acid binding protein 4, adipocyte -0.00854922
GPR171 G protein-coupled receptor 171 -0.00854079
RSAD2 radical S-adenosyl methionine domain containing 2 -0.00851175
JCHAIN joining chain of multimeric IgA and IgM -0.00849692
PALLD palladin, cytoskeletal associated protein -0.00847864
PDLIM2 PDZ and LIM domain 2 (mystique) -0.00844107
SFRP1 secreted frizzled-related protein 1 -0.00842643
ZBED2 zinc finger, BED-type containing 2 -0.00840758
BAG2 BCL2-associated athanogene 2 -0.00839625
MXRA7 matrix-remodelling associated 7 -0.00836192
RRAGD Ras-related GTP binding D -0.00835189
KLF9 Kruppel-like factor 9 -0.00833993
OXTR oxytocin receptor -0.00833226
HSPA1A heat shock 70kDa protein 1A -0.00830278
GABARAPL2 GABA(A) receptor-associated protein-like 2 -0.00823031
PON2 paraoxonase 2 -0.00822697
STOM stomatin -0.00820301
CX3CL1 chemokine (C-X3-C motif) ligand 1 -0.00819983
HK1 hexokinase 1 -0.00818226
BTN3A2 butyrophilin, subfamily 3, member A2 -0.00816946
PRAME preferentially expressed antigen in melanoma -0.00814157
TAC1 tachykinin, precursor 1 -0.0080912
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 -0.00806901
ARL4A ADP-ribosylation factor-like 4A -0.00801603
TRIM29 tripartite motif containing 29 -0.00800999
C1S complement component 1, s subcomponent -0.00800482
UBE2E3 ubiquitin-conjugating enzyme E2E 3 -0.0079653
CFB complement factor B -0.00794846
USP18 ubiquitin specific peptidase 18 -0.0078978
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 -0.00788856
MX1 MX dynamin-like GTPase 1 -0.00787961
GIMAP4 GTPase, IMAP family member 4 -0.0078764
MARCKS myristoylated alanine-rich protein kinase C substrate -0.00787628
IL1RN interleukin 1 receptor antagonist -0.00786042
BTG3 BTG family, member 3 -0.00783715
LYPD1 LY6/PLAUR domain containing 1 -0.00781835
AKAP12 A kinase (PRKA) anchor protein 12 -0.00778825
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) -0.00777522
BCL2A1 BCL2-related protein A1 -0.00776899
PI3 peptidase inhibitor 3, skin-derived -0.00775112
PFN2 profilin 2 -0.00772433
C5AR1 complement component 5a receptor 1 -0.00769315
IVNS1ABP influenza virus NS1A binding protein -0.00767429
PEA15 phosphoprotein enriched in astrocytes 15 -0.00762421
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A -0.00762204
RGS1 regulator of G-protein signaling 1 -0.00760232
VSIG4 V-set and immunoglobulin domain containing 4 -0.00759122
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) -0.0075734
HTRA2 HtrA serine peptidase 2 -0.00756628
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein -0.00751914
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) -0.00751179
ZIC1 Zic family member 1 -0.00751132
LYST lysosomal trafficking regulator -0.00749494
SPRR1B small proline-rich protein 1B -0.00749159
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 -0.00748527
EMP1 epithelial membrane protein 1 -0.00747871
ALOX5AP arachidonate 5-lipoxygenase-activating protein -0.00747592
KRT6A keratin 6A, type II -0.007433
EDNRB endothelin receptor type B -0.00737826
GIMAP6 GTPase, IMAP family member 6 -0.00735104
STAB1 stabilin 1 -0.00734855
FOSB FBJ murine osteosarcoma viral oncogene homolog B -0.00734454
GARS1 glycyl-tRNA synthetase 1 -0.00733809
EREG epiregulin -0.00733769
IFIH1 interferon induced with helicase C domain 1 -0.00733766
PLTP phospholipid transfer protein -0.00726697
ALAS2 5'-aminolevulinate synthase 2 -0.00725827
EGR1 early growth response 1 -0.0072573
SNAI2 snail family zinc finger 2 -0.0072038
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 -0.00720012
SOX9 SRY (sex determining region Y)-box 9 -0.00719896
CHN1 chimerin 1 -0.00717962
EGFL6 EGF-like-domain, multiple 6 -0.00717769
ATF7IP activating transcription factor 7 interacting protein -0.00717195
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa -0.00716439
LPIN1 lipin 1 -0.00715913
IFI35 interferon-induced protein 35 -0.00715002
MLF1 myeloid leukemia factor 1 -0.00714904
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) -0.00711713
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B -0.00710747
MUC16 mucin 16, cell surface associated -0.0070611
NBAS neuroblastoma amplified sequence -0.00705239
AMDHD2 amidohydrolase domain containing 2 -0.00702701
EGR3 early growth response 3 -0.00701491
WDR26 WD repeat domain 26 -0.00701369
CST7 cystatin F (leukocystatin) -0.0069906
LAPTM4B lysosomal protein transmembrane 4 beta -0.00693977
RPS5 ribosomal protein S5 -0.00692943
SST somatostatin -0.00690912
IL1B interleukin 1, beta -0.00690835
CRABP2 cellular retinoic acid binding protein 2 -0.00688418
ASS1 argininosuccinate synthase 1 -0.00686143
S100A2 S100 calcium binding protein A2 -0.00683719
IFI30 interferon, gamma-inducible protein 30 -0.0068366
AKAP8L A kinase (PRKA) anchor protein 8-like -0.00682144
CCL4 chemokine (C-C motif) ligand 4 -0.00680432
CYBRD1 cytochrome b reductase 1 -0.00680187
MSMO1 methylsterol monooxygenase 1 -0.00677666
SGCE sarcoglycan, epsilon -0.00676743
KIFAP3 kinesin-associated protein 3 -0.00674543
IL2RB interleukin 2 receptor, beta -0.00674246
H1-2 H1.2 linker histone, cluster member -0.00673594
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) -0.00673085
KRT6B keratin 6B, type II -0.0067265
GSTA4 glutathione S-transferase alpha 4 -0.00671838
RNF144A ring finger protein 144A -0.00671581
GABRP gamma-aminobutyric acid (GABA) A receptor, pi -0.00671309
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -0.00668946
S100P S100 calcium binding protein P -0.0066672
PNRC1 proline-rich nuclear receptor coactivator 1 -0.00666516
MEIS1 Meis homeobox 1 -0.00663527
RBKS ribokinase -0.00663382
KLK5 kallikrein-related peptidase 5 -0.00663343
SARS1 seryl-tRNA synthetase 1 -0.00662895
NCALD neurocalcin delta -0.00662342
KRT16 keratin 16, type I -0.00661986
RANBP9 RAN binding protein 9 -0.00661857
ABAT 4-aminobutyrate aminotransferase -0.0066147
C10ORF10 chromosome 10 open reading frame 10 -0.00661163
SPARCL1 SPARC-like 1 (hevin) -0.00660641
AQP3 aquaporin 3 (Gill blood group) -0.00658881
VAMP5 vesicle-associated membrane protein 5 -0.0065645
LRRN3 leucine rich repeat neuronal 3 -0.00655555
TAPBP TAP binding protein (tapasin) -0.00654053
TUBB2B tubulin, beta 2B class IIb -0.00653275
SIAH2 siah E3 ubiquitin protein ligase 2 -0.00653196
FKBP11 FK506 binding protein 11, 19 kDa -0.0065294
FOSL2 FOS-like antigen 2 -0.00650772
CD36 CD36 molecule (thrombospondin receptor) -0.00649679
CAST calpastatin -0.00649618
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 -0.0064942
CP ceruloplasmin (ferroxidase) -0.00649134
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide -0.00648758
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) -0.00648366
HIST1H2BK histone cluster 1, H2bk -0.00648272
EMC3 ER membrane protein complex subunit 3 -0.00647437
RAB9A RAB9A, member RAS oncogene family -0.00646892
ABHD4 abhydrolase domain containing 4 -0.00645571
RGS2 regulator of G-protein signaling 2 -0.00643341
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 -0.00642775
LMCD1 LIM and cysteine-rich domains 1 -0.00642351
G6PD glucose-6-phosphate dehydrogenase -0.00642047
DPH5 diphthamide biosynthesis 5 -0.00641697
PER1 period circadian clock 1 -0.00640244
RGCC regulator of cell cycle -0.00634846
PITX3 paired-like homeodomain 3 -0.00634658
MPP1 membrane protein, palmitoylated 1, 55kDa -0.00632971
LCP1 lymphocyte cytosolic protein 1 (L-plastin) -0.00632468
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) -0.00632441
CETN2 centrin, EF-hand protein, 2 -0.00631533
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1) -0.00630126
SELL selectin L -0.00629891
PHLDA1 pleckstrin homology-like domain, family A, member 1 -0.00629245
KYNU kynureninase -0.00629216
HACD1 3-hydroxyacyl-CoA dehydratase 1 -0.00628099
EPAS1 endothelial PAS domain protein 1 -0.00627951
NRN1 neuritin 1 -0.00627621
RTN2 reticulon 2 -0.00626261
LRRC17 leucine rich repeat containing 17 -0.00625807
ITK IL2-inducible T-cell kinase -0.0062568
IL2RA interleukin 2 receptor, alpha -0.00625619
FBXL12 F-box and leucine-rich repeat protein 12 -0.00625128
SORT1 sortilin 1 -0.00625013
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 -0.00623148
SPCS1 signal peptidase complex subunit 1 homolog (S. cerevisiae) -0.00621844
CSNK2B casein kinase 2, beta polypeptide -0.0062135
CLDN8 claudin 8 -0.00621259
IRF6 interferon regulatory factor 6 -0.00621185
IDS iduronate 2-sulfatase -0.00620814
MCL1 myeloid cell leukemia 1 -0.00620611
DST dystonin -0.00619765
TMEM100 transmembrane protein 100 -0.00618495
SMYD2 SET and MYND domain containing 2 -0.00617601
GTF3C3 general transcription factor IIIC, polypeptide 3, 102kDa -0.00616325
CD69 CD69 molecule -0.00616216
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 -0.00615929
ATOX1 antioxidant 1 copper chaperone -0.0061346
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 -0.00613038
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha -0.00612807
HSPH1 heat shock 105kDa/110kDa protein 1 -0.00612555
KLHL24 kelch-like family member 24 -0.00612248
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 -0.00608783
HOMER1 homer scaffolding protein 1 -0.00607168
RDX radixin -0.00606247
AMZ2 archaelysin family metallopeptidase 2 -0.006057
CCL5 chemokine (C-C motif) ligand 5 -0.00605355
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein -0.0060512
GBP1 guanylate binding protein 1, interferon-inducible -0.00605084