BANF1 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description barrier to autointegration factor 1|The protein encoded by this gene was first identified by its ability to protect retroviruses from intramolecular integration and therefore promote intermolecular integration into the host cell genome. The protein forms a homodimer which localizes to both the nucleus and cytoplasm and is specifically associated with chromosomes during mitosis. This protein binds to double stranded DNA in a non-specific manner and also binds to LEM-domain containing proteins of the nuclear envelope. This protein is thought to facilitate nuclear reassembly by binding with both DNA and inner nuclear membrane proteins and thereby recruit chromatin to the nuclear periphery. Alternative splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, Jan 2009] (NCBI Entrez Gene Database, 8815)
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Genes

306 genes differentially expressed following the BANF1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
CD33 CD33 molecule 2.77534
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa 2.77534
CNTN6 contactin 6 2.77534
CLEC4A C-type lectin domain family 4, member A 2.77534
IRX3 iroquois homeobox 3 2.77534
ABCC11 ATP-binding cassette, sub-family C (CFTR/MRP), member 11 2.77534
PLB1 phospholipase B1 2.77534
TUBB1 tubulin, beta 1 class VI 2.77534
CATSPER3 cation channel, sperm associated 3 2.77534
CRYGN crystallin, gamma N 2.77534
C4ORF17 chromosome 4 open reading frame 17 2.77534
MYL7 myosin, light chain 7, regulatory 2.77534
H2BW2 H2B.W histone 2 2.77534
PRSS36 protease, serine, 36 2.77534
FAM107A family with sequence similarity 107, member A 2.77534
AGTR1 angiotensin II receptor, type 1 2.77534
SLX1A SLX1 structure-specific endonuclease subunit homolog A (S. cerevisiae) 2.77534
F5 coagulation factor V (proaccelerin, labile factor) 2.77534
MUC6 mucin 6, oligomeric mucus/gel-forming 2.75243
ZFP57 ZFP57 zinc finger protein 2.75243
PRODH2 proline dehydrogenase (oxidase) 2 2.75243
SSTR1 somatostatin receptor 1 2.75243
IL22RA2 interleukin 22 receptor, alpha 2 2.75243
IGFL3 IGF-like family member 3 2.75243
HMGCLL1 3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1 2.75243
ADGRE3 adhesion G protein-coupled receptor E3 2.75243
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime 2.75243
LY86 lymphocyte antigen 86 2.75243
CD6 CD6 molecule 2.75243
SLFN11 schlafen family member 11 2.75243
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15 2.75243
HBA1 hemoglobin, alpha 1 2.75243
LYNX1 Ly6/neurotoxin 1 2.75243
LRRC63 leucine rich repeat containing 63 2.75243
COPZ2 coatomer protein complex, subunit zeta 2 2.75243
FSCN2 fascin actin-bundling protein 2, retinal 2.75243
ATF7 activating transcription factor 7 2.75243
PTGER4 prostaglandin E receptor 4 (subtype EP4) 2.75243
YIPF7 Yip1 domain family, member 7 2.75243
REN renin 2.75243
MFAP4 microfibrillar-associated protein 4 2.75243
DIRAS2 DIRAS family, GTP-binding RAS-like 2 2.75243
RSPO3 R-spondin 3 2.75243
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2 2.75243
GFAP glial fibrillary acidic protein 2.75243
FETUB fetuin B 2.75243
FAM90A1 family with sequence similarity 90, member A1 2.75243
HAS1 hyaluronan synthase 1 2.75243
TAS2R5 taste receptor, type 2, member 5 2.75243
ABCA9 ATP-binding cassette, sub-family A (ABC1), member 9 2.75243
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) 2.75243
IMPG1 interphotoreceptor matrix proteoglycan 1 2.75243
DOK7 docking protein 7 2.75243
PDC phosducin 2.75243
MLN motilin 2.75243
KRT80 keratin 80, type II 2.75243
FRG2C FSHD region gene 2 family, member C 2.75243
LDB3 LIM domain binding 3 2.75243
GBP3 guanylate binding protein 3 2.75243
OTOA otoancorin 2.75243
VSIR V-set immunoregulatory receptor 2.75243
CFAP100 cilia and flagella associated protein 100 2.75243
CHCT1 CHD1 helical C-terminal domain containing 1 2.75243
CLEC20A C-type lectin domain containing 20A 2.75243
HOATZ HOATZ cilia and flagella associated protein 2.75243
SPMAP2 sperm microtubule associated protein 2 2.75243
GATA4 GATA binding protein 4 2.75243
ROPN1 rhophilin associated tail protein 1 2.75243
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 2.75243
ZNF98 zinc finger protein 98 2.75243
FPR1 formyl peptide receptor 1 2.75243
FPR2 formyl peptide receptor 2 2.75243
MAGEB3 melanoma antigen family B3 2.75243
VSX2 visual system homeobox 2 2.75243
CKM creatine kinase, muscle 2.75243
ANXA10 annexin A10 2.75243
MSX1 msh homeobox 1 2.75243
SCRT2 scratch family zinc finger 2 2.75243
HAPLN2 hyaluronan and proteoglycan link protein 2 2.75243
TPTE transmembrane phosphatase with tensin homology 2.75243
CREB3L3 cAMP responsive element binding protein 3-like 3 2.75243
CCR8 chemokine (C-C motif) receptor 8 2.75243
C9 complement component 9 2.75243
OPN4 opsin 4 2.75243
LRRC73 leucine rich repeat containing 73 2.75243
LOC124906892 uncharacterized LOC124906892 2.75243
ATOH8 atonal homolog 8 (Drosophila) 2.75243
SLC36A3 solute carrier family 36, member 3 2.75243
C2CD4A C2 calcium-dependent domain containing 4A 2.75243
CD5L CD5 molecule-like 2.75243
CAMK2B calcium/calmodulin-dependent protein kinase II beta 2.75243
AQP7 aquaporin 7 2.75243
C11ORF91 chromosome 11 open reading frame 91 2.75243
BTNL3 butyrophilin-like 3 2.75243
EFCAB3 EF-hand calcium binding domain 3 2.75243
KCNA6 potassium channel, voltage gated shaker related subfamily A, member 6 2.75243
RFX4 regulatory factor X, 4 (influences HLA class II expression) 2.75243
GAGE10 G antigen 10 2.75243
KCNK9 potassium channel, two pore domain subfamily K, member 9 2.75243
TMEM132E transmembrane protein 132E 2.75243
PCDHGB4 protocadherin gamma subfamily B, 4 2.75243
DUSP26 dual specificity phosphatase 26 (putative) 2.75243
DBX2 developing brain homeobox 2 2.75243
CARD6 caspase recruitment domain family, member 6 2.75243
POTEI POTE ankyrin domain family, member I 2.75243
ANKFN1 ankyrin-repeat and fibronectin type III domain containing 1 2.75243
WNT7A wingless-type MMTV integration site family, member 7A 2.75243
ART1 ADP-ribosyltransferase 1 2.75243
PHOX2A paired-like homeobox 2a 2.75243
NLRP14 NLR family, pyrin domain containing 14 2.75243
CCDC170 coiled-coil domain containing 170 2.75243
NPM2 nucleophosmin/nucleoplasmin 2 2.75243
KCNA4 potassium channel, voltage gated shaker related subfamily A, member 4 2.75243
FAIM2 Fas apoptotic inhibitory molecule 2 2.75243
EFCAB12 EF-hand calcium binding domain 12 2.75243
SLC38A3 solute carrier family 38, member 3 2.75243
OR5B2 olfactory receptor, family 5, subfamily B, member 2 2.75243
OR4D2 olfactory receptor, family 4, subfamily D, member 2 2.75243
PRSS38 protease, serine, 38 2.75243
TPTE2 transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 2.75243
GDPD4 glycerophosphodiester phosphodiesterase domain containing 4 2.75243
GPR37L1 G protein-coupled receptor 37 like 1 2.75243
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 2.75243
KLK11 kallikrein-related peptidase 11 2.75243
MMP3 matrix metallopeptidase 3 2.75243
DUOXA1 dual oxidase maturation factor 1 2.75243
RNF148 ring finger protein 148 2.75243
PCDHGA11 protocadherin gamma subfamily A, 11 2.75243
SETD3 SET domain containing 3 2.75243
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 2.75243
FXYD3 FXYD domain containing ion transport regulator 3 2.75243
R3HDML R3H domain containing-like 2.75243
LPA lipoprotein, Lp(a) 2.75243
SPNS3 spinster homolog 3 (Drosophila) 2.75243
PPP1R3C protein phosphatase 1, regulatory subunit 3C 2.75243
TAS2R46 taste receptor, type 2, member 46 2.75243
ANXA1 annexin A1 2.75243
LRRC31 leucine rich repeat containing 31 2.75243
OIT3 oncoprotein induced transcript 3 2.75243
ACOT12 acyl-CoA thioesterase 12 2.75243
DDX53 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 2.75243
MPL MPL proto-oncogene, thrombopoietin receptor 2.75243
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal) 2.75243
APOL3 apolipoprotein L, 3 2.75243
ASAH2 N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2 2.75243
MYOZ2 myozenin 2 2.75243
PRKCB protein kinase C, beta 2.71856
GSDMA gasdermin A 2.66883
G2E3 G2/M-phase specific E3 ubiquitin protein ligase 2.64698
NFYC nuclear transcription factor Y, gamma 2.61159
PYCR3 pyrroline-5-carboxylate reductase 3 2.55541
PAM16 presequence translocase-associated motor 16 homolog (S. cerevisiae) 2.55541
SLC24A5 solute carrier family 24 (sodium/potassium/calcium exchanger), member 5 2.53558
CTSL cathepsin L 2.53558
ACSL5 acyl-CoA synthetase long-chain family member 5 2.53558
PTPRG protein tyrosine phosphatase, receptor type, G 2.4624
NHP2 NHP2 ribonucleoprotein 2.4612
PNISR PNN-interacting serine/arginine-rich protein 2.45737
MESP2 mesoderm posterior basic helix-loop-helix transcription factor 2 2.44038
AURKAIP1 aurora kinase A interacting protein 1 2.43086
RPLP0 ribosomal protein, large, P0 2.42667
KCNA7 potassium channel, voltage gated shaker related subfamily A, member 7 2.41032
PHYH phytanoyl-CoA 2-hydroxylase 2.41032
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 2.41032
PLEKHG4B pleckstrin homology domain containing, family G (with RhoGef domain) member 4B 2.41032
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor 2.37684
STYXL1 serine/threonine/tyrosine interacting-like 1 2.35654
MEGF8 multiple EGF-like-domains 8 2.35073
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 2.33898
MRPL51 mitochondrial ribosomal protein L51 2.32205
EIF4A3 eukaryotic translation initiation factor 4A3 2.29557
NPHP3 nephronophthisis 3 (adolescent) 2.26945
CMTM3 CKLF-like MARVEL transmembrane domain containing 3 2.26722
TRIAP1 TP53 regulated inhibitor of apoptosis 1 2.22557
ATL2 atlastin GTPase 2 2.21552
PARD6G par-6 family cell polarity regulator gamma 2.18434
ZNF318 zinc finger protein 318 2.18305
DENND2A DENN/MADD domain containing 2A 2.178
LMNB1 lamin B1 2.17793
FDXR ferredoxin reductase 2.16895
FBXO22 F-box protein 22 2.16895
TGIF1 TGFB-induced factor homeobox 1 2.16453
PTPRE protein tyrosine phosphatase, receptor type, E 2.15325
CCDC191 coiled-coil domain containing 191 2.14189
KPTN kaptin (actin binding protein) 2.13155
SLC18B1 solute carrier family 18, subfamily B, member 1 2.1289
YJU2B YJU2 splicing factor homolog B 2.12271
SAMD1 sterile alpha motif domain containing 1 2.10932
B4GALT4 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 2.10401
PER3 period circadian clock 3 2.10162
CHST10 carbohydrate sulfotransferase 10 2.08422
PJA1 praja ring finger 1, E3 ubiquitin protein ligase 2.06045
ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif, 6 2.06045
TMEM220 transmembrane protein 220 2.02418
LTB4R leukotriene B4 receptor 2.01573
CFAP251 cilia and flagella associated protein 251 2.01047
IRF2BPL interferon regulatory factor 2 binding protein-like 2.00341
FAM20B family with sequence similarity 20, member B 2.00341

decreased expression

Symbol Name Standardized Value
OXSM 3-oxoacyl-ACP synthase, mitochondrial -2.77534
CCL28 chemokine (C-C motif) ligand 28 -2.77534
MADCAM1 mucosal vascular addressin cell adhesion molecule 1 -2.77534
NEURL2 neuralized E3 ubiquitin protein ligase 2 -2.77534
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 -2.75243
CRY1 cryptochrome circadian clock 1 -2.75243
TTC21A tetratricopeptide repeat domain 21A -2.75243
GJA4 gap junction protein, alpha 4, 37kDa -2.75243
ASPG asparaginase -2.75243
CA9 carbonic anhydrase IX -2.75243
TMEM200C transmembrane protein 200C -2.75243
POP5 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) -2.75243
ODAD4 outer dynein arm docking complex subunit 4 -2.75243
ZBTB20 zinc finger and BTB domain containing 20 -2.75243
CARMIL3 capping protein regulator and myosin 1 linker 3 -2.75243
ZNF526 zinc finger protein 526 -2.75243
SYT6 synaptotagmin VI -2.75243
XIRP2 xin actin binding repeat containing 2 -2.75243
PELI1 pellino E3 ubiquitin protein ligase 1 -2.7421
REEP1 receptor accessory protein 1 -2.73115
FADS3 fatty acid desaturase 3 -2.70857
ERVMER34-1 endogenous retrovirus group MER34, member 1 -2.67757
HS1BP3 HCLS1 binding protein 3 -2.66081
FICD FIC domain containing -2.62364
CA3 carbonic anhydrase III -2.62364
CACNG2 calcium channel, voltage-dependent, gamma subunit 2 -2.62364
DGAT1 diacylglycerol O-acyltransferase 1 -2.61159
DENND2B DENN domain containing 2B -2.59065
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 -2.5903
RAB24 RAB24, member RAS oncogene family -2.55541
UBE2U ubiquitin-conjugating enzyme E2U (putative) -2.55541
FBLN7 fibulin 7 -2.55541
FCRL5 Fc receptor-like 5 -2.55541
KCNE1 potassium channel, voltage gated subfamily E regulatory beta subunit 1 -2.55541
ASB14 ankyrin repeat and SOCS box containing 14 -2.55541
TMEM100 transmembrane protein 100 -2.55541
KCND1 potassium channel, voltage gated Shal related subfamily D, member 1 -2.55541
HSPB6 heat shock protein, alpha-crystallin-related, B6 -2.55541
CXCL14 chemokine (C-X-C motif) ligand 14 -2.55541
RASD2 RASD family, member 2 -2.55541
NPAP1 nuclear pore associated protein 1 -2.55541
TSSK6 testis-specific serine kinase 6 -2.55541
ACE2 angiotensin I converting enzyme 2 -2.55541
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) -2.55541
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8 -2.55541
ECEL1 endothelin converting enzyme-like 1 -2.55541
COL15A1 collagen, type XV, alpha 1 -2.55541
GPR149 G protein-coupled receptor 149 -2.55541
TMEM86A transmembrane protein 86A -2.55541
CPM carboxypeptidase M -2.55541
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7 -2.55541
GP1BA glycoprotein Ib (platelet), alpha polypeptide -2.55541
NACA2 nascent polypeptide-associated complex alpha subunit 2 -2.55541
CLIC5 chloride intracellular channel 5 -2.55541
DNAH12 dynein, axonemal, heavy chain 12 -2.55541
RAD9B RAD9 homolog B (S. pombe) -2.55541
PSD4 pleckstrin and Sec7 domain containing 4 -2.55541
WAS Wiskott-Aldrich syndrome -2.55541
DNAH2 dynein, axonemal, heavy chain 2 -2.55541
SCIN scinderin -2.55541
NPIPA2 nuclear pore complex interacting protein family, member A2 -2.55541
GNRHR gonadotropin-releasing hormone receptor -2.55541
PRLR prolactin receptor -2.42667
ZNF57 zinc finger protein 57 -2.42667
CASTOR1 cytosolic arginine sensor for mTORC1 subunit 1 -2.42323
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal) -2.41571
PPAN peter pan homolog (Drosophila) -2.41032
H2AC13 H2A clustered histone 13 -2.38323
ARHGAP31 Rho GTPase activating protein 31 -2.37684
ARMH4 armadillo like helical domain containing 4 -2.37331
WWC1 WW and C2 domain containing 1 -2.35707
FAM114A1 family with sequence similarity 114, member A1 -2.35106
MBD2 methyl-CpG binding domain protein 2 -2.33067
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F -2.32827
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G -2.32827
ATG9B autophagy related 9B -2.32827
GARIN1B golgi associated RAB2 interactor 1B -2.3163
CAPN15 calpain 15 -2.29061
P3H3 prolyl 3-hydroxylase 3 -2.29061
GRM2 glutamate receptor, metabotropic 2 -2.2259
LRRC3 leucine rich repeat containing 3 -2.2259
BTN3A2 butyrophilin, subfamily 3, member A2 -2.2259
MMRN2 multimerin 2 -2.2259
TRABD2A TraB domain containing 2A -2.2259
MYO1H myosin IH -2.22557
TSNAX translin-associated factor X -2.16895
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial) -2.15904
PTP4A2 protein tyrosine phosphatase type IVA, member 2 -2.15904
CALR calreticulin -2.13565
ACIN1 apoptotic chromatin condensation inducer 1 -2.13155
ELMO2 engulfment and cell motility 2 -2.1289
COPS7A COP9 signalosome subunit 7A -2.12271
ANKHD1 ankyrin repeat and KH domain containing 1 -2.10561
TRIM58 tripartite motif containing 58 -2.10401
LBR lamin B receptor -2.09102
GSG1L GSG1-like -2.06642
KBTBD11 kelch repeat and BTB (POZ) domain containing 11 -2.06642
LHCGR luteinizing hormone/choriogonadotropin receptor -2.06642
FSTL4 follistatin-like 4 -2.04937
FJX1 four jointed box 1 (Drosophila) -2.03221
DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B -2.02829
USP11 ubiquitin specific peptidase 11 -2.02829
GIPC2 GIPC PDZ domain containing family, member 2 -2.02418
CCDC69 coiled-coil domain containing 69 -2.01732
NAA20 N(alpha)-acetyltransferase 20, NatB catalytic subunit -2.01126
STK38 serine/threonine kinase 38 -2.01126
ADGRL4 adhesion G protein-coupled receptor L4 -2.00981
BPGM 2,3-bisphosphoglycerate mutase -2.00103