| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | BCL2-associated X protein|The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 581) |
| External Link | https://ncbi.nlm.nih.gov/gene/581 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the BAX gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.0139055 |
| CA2 | carbonic anhydrase II | 0.0138267 |
| TFRC | transferrin receptor | 0.0111099 |
| ADM | adrenomedullin | 0.00930522 |
| NIBAN1 | niban apoptosis regulator 1 | 0.00929047 |
| EGR2 | early growth response 2 | 0.00918634 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 0.00819587 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | 0.00803653 |
| HOPX | HOP homeobox | 0.00801624 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | 0.00762727 |
| MYBPC1 | myosin binding protein C, slow type | 0.00748409 |
| FKBP4 | FK506 binding protein 4, 59kDa | 0.00728478 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.00727837 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 0.00710207 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | 0.00709708 |
| LAMP3 | lysosomal-associated membrane protein 3 | 0.00702276 |
| AREG | amphiregulin | 0.00657021 |
| STC2 | stanniocalcin 2 | 0.00656733 |
| VAV3 | vav 3 guanine nucleotide exchange factor | 0.00653114 |
| SLC31A2 | solute carrier family 31 (copper transporter), member 2 | 0.00652545 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.00638766 |
| FGFR2 | fibroblast growth factor receptor 2 | 0.00636281 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 0.00621794 |
| BAG3 | BCL2-associated athanogene 3 | 0.00613362 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.00606227 |
| CYB5A | cytochrome b5 type A (microsomal) | 0.00601987 |
| KDM5D | lysine (K)-specific demethylase 5D | 0.00590643 |
| FCER1A | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide | 0.0058467 |
| MYL2 | myosin, light chain 2, regulatory, cardiac, slow | 0.00581983 |
| RGCC | regulator of cell cycle | 0.00579559 |
| WNT5A | wingless-type MMTV integration site family, member 5A | 0.00577318 |
| CSTA | cystatin A (stefin A) | 0.00574927 |
| FABP4 | fatty acid binding protein 4, adipocyte | 0.00563137 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') | 0.00559821 |
| GSTM3 | glutathione S-transferase mu 3 (brain) | 0.00557302 |
| PPL | periplakin | 0.00554107 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 | 0.00553612 |
| SDC4 | syndecan 4 | 0.00552672 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | 0.00552321 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | 0.00551339 |
| MXI1 | MAX interactor 1, dimerization protein | 0.00535332 |
| SIRPA | signal-regulatory protein alpha | 0.00532163 |
| GRB7 | growth factor receptor-bound protein 7 | 0.00525859 |
| DAXX | death-domain associated protein | 0.00525815 |
| SPRR1B | small proline-rich protein 1B | 0.00524024 |
| CALML3 | calmodulin-like 3 | 0.00523966 |
| COL15A1 | collagen, type XV, alpha 1 | 0.00520659 |
| KLF4 | Kruppel-like factor 4 (gut) | 0.00518358 |
| CARHSP1 | calcium regulated heat stable protein 1, 24kDa | 0.00517926 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) | 0.00517467 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.00506088 |
| SPRR1A | small proline-rich protein 1A | 0.00504747 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | 0.0050417 |
| CLCA2 | chloride channel accessory 2 | 0.00503369 |
| SH3YL1 | SH3 and SYLF domain containing 1 | 0.00503163 |
| NDUFA4L2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 | 0.00502912 |
| CLTB | clathrin, light chain B | 0.00502855 |
| TMEM45A | transmembrane protein 45A | 0.00500661 |
| SSPN | sarcospan | 0.00500601 |
| HSPA4 | heat shock 70kDa protein 4 | 0.00497196 |
| EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase | 0.00496079 |
| MCL1 | myeloid cell leukemia 1 | 0.00494002 |
| GREM1 | gremlin 1, DAN family BMP antagonist | 0.00493418 |
| NEBL | nebulette | 0.00493119 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.00493058 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.00492361 |
| SFTPA2 | surfactant protein A2 | 0.00489698 |
| GEM | GTP binding protein overexpressed in skeletal muscle | 0.00488373 |
| ATF3 | activating transcription factor 3 | 0.00485235 |
| UFM1 | ubiquitin-fold modifier 1 | 0.00484655 |
| TCAP | titin-cap | 0.00480895 |
| TNNC1 | troponin C type 1 (slow) | 0.00480829 |
| SFTPC | surfactant protein C | 0.00478076 |
| MAGEA3 | melanoma antigen family A3 | 0.00477629 |
| EIF5A | eukaryotic translation initiation factor 5A | 0.00474048 |
| ASPN | asporin | 0.00473979 |
| COQ8A | coenzyme Q8A | 0.00472875 |
| CDK18 | cyclin-dependent kinase 18 | 0.0047173 |
| G0S2 | G0/G1 switch 2 | 0.00467503 |
| HIST1H2AC | histone cluster 1, H2ac | 0.00465145 |
| CD1C | CD1c molecule | 0.00460625 |
| TNNT1 | troponin T type 1 (skeletal, slow) | 0.00459608 |
| CTSV | cathepsin V | 0.00459433 |
| CPOX | coproporphyrinogen oxidase | 0.00459209 |
| FILIP1L | filamin A interacting protein 1-like | 0.00459137 |
| CH25H | cholesterol 25-hydroxylase | 0.00459048 |
| CYP26B1 | cytochrome P450, family 26, subfamily B, polypeptide 1 | 0.00455582 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0045088 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.00449654 |
| DRAM1 | DNA-damage regulated autophagy modulator 1 | 0.00449468 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.00449225 |
| SPINT1 | serine peptidase inhibitor, Kunitz type 1 | 0.00447846 |
| CDS1 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 | 0.00447051 |
| AQP1 | aquaporin 1 (Colton blood group) | 0.0044629 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.00446201 |
| MB | myoglobin | 0.00444729 |
| PKP1 | plakophilin 1 | 0.0044446 |
| HSPB8 | heat shock 22kDa protein 8 | 0.00442513 |
| INHBB | inhibin, beta B | 0.00441794 |
| PTHLH | parathyroid hormone-like hormone | 0.00441578 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | 0.00441225 |
| CST6 | cystatin E/M | 0.00441202 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | 0.00440411 |
| PLP2 | proteolipid protein 2 (colonic epithelium-enriched) | 0.00440323 |
| TFAP2C | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) | 0.00438914 |
| KRT16 | keratin 16, type I | 0.00438878 |
| RGS10 | regulator of G-protein signaling 10 | 0.00438181 |
| TTN | titin | 0.00435399 |
| MYH2 | myosin, heavy chain 2, skeletal muscle, adult | 0.00434788 |
| NOTCH3 | notch 3 | 0.00434611 |
| SH3BGR | SH3 domain binding glutamate-rich protein | 0.00432918 |
| LAMB3 | laminin, beta 3 | 0.00429651 |
| MPHOSPH6 | M-phase phosphoprotein 6 | 0.00428175 |
| MOXD1 | monooxygenase, DBH-like 1 | 0.00427244 |
| CD99 | CD99 molecule | 0.00427062 |
| STK39 | serine threonine kinase 39 | 0.00426426 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.00425743 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 0.00425474 |
| RAB9A | RAB9A, member RAS oncogene family | 0.00423224 |
| F13A1 | coagulation factor XIII, A1 polypeptide | 0.00422976 |
| FZD5 | frizzled class receptor 5 | 0.00422004 |
| MYOZ1 | myozenin 1 | 0.00421282 |
| CLEC10A | C-type lectin domain family 10, member A | 0.00421159 |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 | 0.00420919 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 | 0.00418019 |
| BID | BH3 interacting domain death agonist | 0.00417384 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A | 0.00416543 |
| EML1 | echinoderm microtubule associated protein like 1 | 0.00414737 |
| STX4 | syntaxin 4 | 0.00410101 |
| FBLN1 | fibulin 1 | 0.00409567 |
| ATG3 | autophagy related 3 | 0.0040915 |
| TUFT1 | tuftelin 1 | 0.00408144 |
| LY96 | lymphocyte antigen 96 | 0.00407416 |
| PEA15 | phosphoprotein enriched in astrocytes 15 | 0.00405662 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | 0.00405483 |
| LEPROT | leptin receptor overlapping transcript | 0.00405401 |
| TPM3 | tropomyosin 3 | 0.00404878 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 0.00403997 |
| ULK2 | unc-51 like autophagy activating kinase 2 | 0.00403156 |
| COL14A1 | collagen, type XIV, alpha 1 | 0.00401419 |
| LHFP | lipoma HMGIC fusion partner | 0.00401137 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 | 0.00400305 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | 0.00399127 |
| LARP6 | La ribonucleoprotein domain family, member 6 | 0.0039878 |
| LDB3 | LIM domain binding 3 | 0.00397669 |
| PPIF | peptidylprolyl isomerase F | 0.00397536 |
| KYNU | kynureninase | 0.00396813 |
| AK4 | adenylate kinase 4 | 0.00395996 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.00395322 |
| SARS1 | seryl-tRNA synthetase 1 | 0.00395194 |
| HSPA4L | heat shock 70kDa protein 4-like | 0.00394343 |
| ACOT9 | acyl-CoA thioesterase 9 | 0.00393223 |
| ZNF451 | zinc finger protein 451 | 0.00392178 |
| MDFIC | MyoD family inhibitor domain containing | 0.00392003 |
| ANOS1 | anosmin 1 | 0.00390919 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.00390173 |
| MYL1 | myosin, light chain 1, alkali; skeletal, fast | 0.00388919 |
| ABCC1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 | 0.00385018 |
| CTTN | cortactin | 0.00384776 |
| MFAP4 | microfibrillar-associated protein 4 | 0.00384608 |
| LOX | lysyl oxidase | 0.00383851 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.0038372 |
| CLDND1 | claudin domain containing 1 | 0.00383461 |
| RABGGTB | Rab geranylgeranyltransferase, beta subunit | 0.00382767 |
| OLFML2B | olfactomedin-like 2B | 0.00381964 |
| TLCD3A | TLC domain containing 3A | 0.00381635 |
| SLCO3A1 | solute carrier organic anion transporter family, member 3A1 | 0.00380048 |
| HCRT | hypocretin (orexin) neuropeptide precursor | 0.00379801 |
| TESK1 | testis-specific kinase 1 | 0.00379423 |
| RAI14 | retinoic acid induced 14 | 0.00378825 |
| THEMIS2 | thymocyte selection associated family member 2 | 0.00378811 |
| RFC5 | replication factor C (activator 1) 5, 36.5kDa | 0.003767 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.00376574 |
| CRCT1 | cysteine-rich C-terminal 1 | 0.00376563 |
| MRPL18 | mitochondrial ribosomal protein L18 | 0.00376144 |
| SLN | sarcolipin | 0.00375032 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 0.00374549 |
| FOXF2 | forkhead box F2 | 0.00374374 |
| ATP2A1 | ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 | 0.00373782 |
| SLC35E3 | solute carrier family 35, member E3 | 0.00373507 |
| MX1 | MX dynamin-like GTPase 1 | 0.00373396 |
| B4GALT4 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 | 0.00373269 |
| TAGLN2 | transgelin 2 | 0.00373059 |
| CELSR2 | cadherin, EGF LAG seven-pass G-type receptor 2 | 0.00372693 |
| CD1A | CD1a molecule | 0.00372576 |
| PTK2 | protein tyrosine kinase 2 | 0.00372479 |
| LPAR1 | lysophosphatidic acid receptor 1 | 0.00372303 |
| METAP2 | methionyl aminopeptidase 2 | 0.00371346 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | 0.00371036 |
| EGR1 | early growth response 1 | 0.00370125 |
| HIST1H2BD | histone cluster 1, H2bd | 0.00370115 |
| RHOD | ras homolog family member D | 0.00369665 |
| FNBP1 | formin binding protein 1 | 0.00368873 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.00368596 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 | 0.00366822 |
| IRF8 | interferon regulatory factor 8 | 0.00366802 |
| DCN | decorin | 0.00366679 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 | 0.00366051 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.00365924 |
| CFD | complement factor D (adipsin) | 0.00364385 |
| FHL1 | four and a half LIM domains 1 | 0.00363688 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 0.00361538 |
| RNF114 | ring finger protein 114 | 0.00361458 |
| HMOX2 | heme oxygenase 2 | 0.00361428 |
| HK2 | hexokinase 2 | 0.00360259 |
| AMDHD2 | amidohydrolase domain containing 2 | 0.00359192 |
| NCOA3 | nuclear receptor coactivator 3 | 0.00358647 |
| TNNI1 | troponin I type 1 (skeletal, slow) | 0.00358243 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.00357696 |
| GSDME | gasdermin E | 0.00357351 |
| MTCL1 | microtubule crosslinking factor 1 | 0.00355475 |
| TPBG | trophoblast glycoprotein | 0.00355388 |
| OSBPL3 | oxysterol binding protein-like 3 | 0.00353821 |
| PSAP | prosaposin | 0.00351698 |
| MET | MET proto-oncogene, receptor tyrosine kinase | 0.0035143 |
| PLAAT3 | phospholipase A and acyltransferase 3 | 0.00351116 |
| BICC1 | BicC family RNA binding protein 1 | 0.00350997 |
| NIT1 | nitrilase 1 | 0.00350721 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | 0.00350563 |
| NCF2 | neutrophil cytosolic factor 2 | 0.00350276 |
| TMEM40 | transmembrane protein 40 | 0.0034972 |
| IER5 | immediate early response 5 | 0.0034842 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | 0.00347036 |
| IL17RB | interleukin 17 receptor B | 0.00345384 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.00344571 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | 0.00344537 |
| SNX13 | sorting nexin 13 | 0.00344531 |
| HCK | HCK proto-oncogene, Src family tyrosine kinase | 0.00343939 |
| SMPX | small muscle protein, X-linked | 0.00342476 |
| UBE3C | ubiquitin protein ligase E3C | 0.00342047 |
| EPCAM | epithelial cell adhesion molecule | 0.00341553 |
| DNALI1 | dynein, axonemal, light intermediate chain 1 | 0.00341275 |
| TUBA3D | tubulin, alpha 3d | 0.00341208 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.00341151 |
| AMMECR1 | Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 | 0.00340867 |
| CHRDL1 | chordin-like 1 | 0.00340816 |
| KRT19 | keratin 19, type I | 0.00340203 |
| FOXC1 | forkhead box C1 | 0.0034002 |
| CD1E | CD1e molecule | 0.00339916 |
| CD86 | CD86 molecule | 0.00339537 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | 0.0033934 |
| RASA2 | RAS p21 protein activator 2 | 0.00339108 |
| SLC38A1 | solute carrier family 38, member 1 | 0.00339088 |
| CASP8 | caspase 8, apoptosis-related cysteine peptidase | 0.00337743 |
| PPP2R3A | protein phosphatase 2, regulatory subunit B'', alpha | 0.00337622 |
| TMEM165 | transmembrane protein 165 | 0.00337172 |
| CCNE1 | cyclin E1 | 0.00337072 |
| CTSE | cathepsin E | 0.00334956 |
| SPRR2B | small proline-rich protein 2B | 0.00334931 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD320 | CD320 molecule | -0.0114825 |
| RHOB | ras homolog family member B | -0.008118 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | -0.00733496 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | -0.00677348 |
| XIC | X chromosome inactivation center | -0.00673239 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | -0.00664671 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | -0.00657431 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 | -0.00654463 |
| PLAT | plasminogen activator, tissue | -0.00652515 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.00635175 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.00627486 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | -0.00622581 |
| RNPS1 | RNA binding protein S1, serine-rich domain | -0.00621733 |
| IQGAP2 | IQ motif containing GTPase activating protein 2 | -0.00609671 |
| CPM | carboxypeptidase M | -0.00597566 |
| PITX3 | paired-like homeodomain 3 | -0.00592676 |
| NEFH | neurofilament, heavy polypeptide | -0.00564594 |
| ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 | -0.00555866 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | -0.00550908 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | -0.00550878 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.00549407 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.00548627 |
| CTSZ | cathepsin Z | -0.00541933 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | -0.005416 |
| APOC1 | apolipoprotein C-I | -0.00539462 |
| HMG20B | high mobility group 20B | -0.00539237 |
| FABP1 | fatty acid binding protein 1, liver | -0.00537235 |
| DDX11 | DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 | -0.00536289 |
| BCHE | butyrylcholinesterase | -0.00535421 |
| S100A11 | S100 calcium binding protein A11 | -0.00530504 |
| FCGBP | Fc fragment of IgG binding protein | -0.0053031 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein | -0.00524805 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.00524601 |
| LIPG | lipase, endothelial | -0.00520771 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0051898 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.00518702 |
| CDO1 | cysteine dioxygenase type 1 | -0.0051822 |
| REEP5 | receptor accessory protein 5 | -0.00516821 |
| TRIB2 | tribbles pseudokinase 2 | -0.00516763 |
| MYRIP | myosin VIIA and Rab interacting protein | -0.00514637 |
| TCTA | T-cell leukemia translocation altered | -0.00511021 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.00510046 |
| S100P | S100 calcium binding protein P | -0.00504071 |
| ZNF580 | zinc finger protein 580 | -0.00500816 |
| TSPAN12 | tetraspanin 12 | -0.00500117 |
| NRCAM | neuronal cell adhesion molecule | -0.00496507 |
| MPPED2 | metallophosphoesterase domain containing 2 | -0.00492011 |
| MTARC1 | mitochondrial amidoxime reducing component 1 | -0.00491695 |
| CLCA1 | chloride channel accessory 1 | -0.00491367 |
| KIF20A | kinesin family member 20A | -0.00488977 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.00485373 |
| SCG5 | secretogranin V | -0.00485249 |
| CHD7 | chromodomain helicase DNA binding protein 7 | -0.00484653 |
| BCL3 | B-cell CLL/lymphoma 3 | -0.00482353 |
| HSPB1 | heat shock 27kDa protein 1 | -0.00481424 |
| LCN2 | lipocalin 2 | -0.00479953 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.00478182 |
| PEG3 | paternally expressed 3 | -0.00475301 |
| KCTD12 | potassium channel tetramerization domain containing 12 | -0.00471975 |
| KLF2 | Kruppel-like factor 2 | -0.00464186 |
| SRPX | sushi-repeat containing protein, X-linked | -0.00462606 |
| EML3 | echinoderm microtubule associated protein like 3 | -0.00461567 |
| MUC2 | mucin 2, oligomeric mucus/gel-forming | -0.00461479 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | -0.00459364 |
| SRGN | serglycin | -0.0045879 |
| OLFM4 | olfactomedin 4 | -0.00456973 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.00455373 |
| NPTX2 | neuronal pentraxin II | -0.00453657 |
| SOCS2 | suppressor of cytokine signaling 2 | -0.00453436 |
| MERTK | MER proto-oncogene, tyrosine kinase | -0.0044738 |
| CD9 | CD9 molecule | -0.00446004 |
| UBE2M | ubiquitin-conjugating enzyme E2M | -0.00444996 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.00444526 |
| DCXR | dicarbonyl/L-xylulose reductase | -0.00444303 |
| SPRY2 | sprouty homolog 2 (Drosophila) | -0.00439727 |
| TGFB1I1 | transforming growth factor beta 1 induced transcript 1 | -0.00437342 |
| RBPMS | RNA binding protein with multiple splicing | -0.00437239 |
| CCL20 | chemokine (C-C motif) ligand 20 | -0.00437007 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.00436874 |
| SPP1 | secreted phosphoprotein 1 | -0.00432925 |
| GDF15 | growth differentiation factor 15 | -0.00432304 |
| ZBTB18 | zinc finger and BTB domain containing 18 | -0.0043153 |
| TARP | TCR gamma alternate reading frame protein | -0.0042982 |
| ZNF22 | zinc finger protein 22 | -0.00429344 |
| PLP1 | proteolipid protein 1 | -0.004277 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.00427691 |
| DACT1 | dishevelled-binding antagonist of beta-catenin 1 | -0.00427117 |
| DCHS1 | dachsous cadherin-related 1 | -0.00426809 |
| CLU | clusterin | -0.00426547 |
| NMNAT2 | nicotinamide nucleotide adenylyltransferase 2 | -0.00426197 |
| QPCT | glutaminyl-peptide cyclotransferase | -0.00423647 |
| EFHD2 | EF-hand domain family, member D2 | -0.00422899 |
| HAS2 | hyaluronan synthase 2 | -0.00422843 |
| KANK1 | KN motif and ankyrin repeat domains 1 | -0.00421537 |
| HP | haptoglobin | -0.0041825 |
| TBC1D4 | TBC1 domain family, member 4 | -0.00416989 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.00416127 |
| ICAM2 | intercellular adhesion molecule 2 | -0.004147 |
| PLK2 | polo-like kinase 2 | -0.00412603 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.00411855 |
| FAM107A | family with sequence similarity 107, member A | -0.00410523 |
| SST | somatostatin | -0.00406091 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | -0.00405411 |
| TSPAN14 | tetraspanin 14 | -0.00405144 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.00404636 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta | -0.00404633 |
| FKBP11 | FK506 binding protein 11, 19 kDa | -0.00404453 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.00400468 |
| MAGED1 | melanoma antigen family D1 | -0.00400417 |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 | -0.0039996 |
| DEFA4 | defensin, alpha 4, corticostatin | -0.00398877 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.00398391 |
| SF3A2 | splicing factor 3a, subunit 2, 66kDa | -0.00397929 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | -0.00397752 |
| EFNB2 | ephrin-B2 | -0.00396978 |
| TIMP4 | TIMP metallopeptidase inhibitor 4 | -0.00396649 |
| TSPAN7 | tetraspanin 7 | -0.00396602 |
| SCN3A | sodium channel, voltage gated, type III alpha subunit | -0.00396114 |
| DOK5 | docking protein 5 | -0.0039536 |
| REG3A | regenerating islet-derived 3 alpha | -0.00395195 |
| PPP1R14B | protein phosphatase 1, regulatory (inhibitor) subunit 14B | -0.00394899 |
| PLIN2 | perilipin 2 | -0.00393683 |
| ZNF544 | zinc finger protein 544 | -0.00393317 |
| NID2 | nidogen 2 (osteonidogen) | -0.00393258 |
| MGP | matrix Gla protein | -0.00393172 |
| NNMT | nicotinamide N-methyltransferase | -0.00392595 |
| NCAM1 | neural cell adhesion molecule 1 | -0.00391569 |
| PCP4 | Purkinje cell protein 4 | -0.00391154 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0039051 |
| SAFB2 | scaffold attachment factor B2 | -0.00390326 |
| IFITM2 | interferon induced transmembrane protein 2 | -0.00389515 |
| CITED1 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 | -0.00388909 |
| PAEP | progestagen-associated endometrial protein | -0.00388439 |
| NAV2 | neuron navigator 2 | -0.0038738 |
| CTH | cystathionine gamma-lyase | -0.0038596 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0038567 |
| DEFA5 | defensin, alpha 5, Paneth cell-specific | -0.00385061 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.00383442 |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial | -0.00381548 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -0.00381123 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.00379459 |
| RTN3 | reticulon 3 | -0.0037862 |
| MYT1L | myelin transcription factor 1-like | -0.00378351 |
| GAP43 | growth associated protein 43 | -0.00378173 |
| DACH1 | dachshund family transcription factor 1 | -0.00377134 |
| UNC13B | unc-13 homolog B (C. elegans) | -0.00377011 |
| GPM6B | glycoprotein M6B | -0.00376852 |
| MRPS16 | mitochondrial ribosomal protein S16 | -0.00376496 |
| SC5D | sterol-C5-desaturase | -0.00376011 |
| PPAP2A | phosphatidic acid phosphatase type 2A | -0.00375636 |
| SMAD7 | SMAD family member 7 | -0.00374973 |
| CNR1 | cannabinoid receptor 1 (brain) | -0.00374688 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.00374229 |
| CEACAM8 | carcinoembryonic antigen-related cell adhesion molecule 8 | -0.0037396 |
| RGS4 | regulator of G-protein signaling 4 | -0.00373768 |
| CUX1 | cut-like homeobox 1 | -0.00373119 |
| ELOVL2 | ELOVL fatty acid elongase 2 | -0.00372734 |
| MUC4 | mucin 4, cell surface associated | -0.00372027 |
| ATP6V0E2 | ATPase, H+ transporting V0 subunit e2 | -0.00371328 |
| IRX5 | iroquois homeobox 5 | -0.00370215 |
| CHMP3 | charged multivesicular body protein 3 | -0.00369348 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | -0.00366806 |
| TBL1X | transducin (beta)-like 1X-linked | -0.0036678 |
| FUCA1 | fucosidase, alpha-L- 1, tissue | -0.00364986 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | -0.00363944 |
| RGS16 | regulator of G-protein signaling 16 | -0.00363279 |
| ABHD14A | abhydrolase domain containing 14A | -0.00362967 |
| CSNK1E | casein kinase 1, epsilon | -0.00362399 |
| ARL6IP5 | ADP-ribosylation factor-like 6 interacting protein 5 | -0.00361775 |
| TMX4 | thioredoxin-related transmembrane protein 4 | -0.00361762 |
| IMPA1 | inositol(myo)-1(or 4)-monophosphatase 1 | -0.00361637 |
| HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 | -0.00360964 |
| CDA | cytidine deaminase | -0.00358886 |
| FKBP2 | FK506 binding protein 2, 13kDa | -0.00358233 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 | -0.00357911 |
| AP5M1 | adaptor-related protein complex 5, mu 1 subunit | -0.00357898 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha | -0.00357249 |
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 | -0.0035705 |
| CXCL6 | chemokine (C-X-C motif) ligand 6 | -0.00356758 |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 | -0.00356494 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | -0.00355724 |
| DPYD | dihydropyrimidine dehydrogenase | -0.00355013 |
| SMC1A | structural maintenance of chromosomes 1A | -0.00354597 |
| HMGB1 | high mobility group box 1 | -0.0035395 |
| DCLK1 | doublecortin-like kinase 1 | -0.00353301 |
| SLC22A1 | solute carrier family 22 (organic cation transporter), member 1 | -0.00353008 |
| SGCG | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) | -0.00352882 |
| MATN2 | matrilin 2 | -0.00351622 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | -0.00350968 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | -0.00350964 |
| FAM110B | family with sequence similarity 110, member B | -0.00349999 |
| PLSCR4 | phospholipid scramblase 4 | -0.00349769 |
| CFHR4 | complement factor H-related 4 | -0.00349111 |
| CTSG | cathepsin G | -0.00346144 |
| FOXO4 | forkhead box O4 | -0.00345626 |
| ANKRD10 | ankyrin repeat domain 10 | -0.00344891 |
| DGCR8 | DGCR8 microprocessor complex subunit | -0.00344134 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.00343744 |
| BPI | bactericidal/permeability-increasing protein | -0.00343575 |
| CD14 | CD14 molecule | -0.00342978 |
| PMEL | premelanosome protein | -0.00342478 |
| CYP3A4 | cytochrome P450, family 3, subfamily A, polypeptide 4 | -0.00342116 |
| MGLL | monoglyceride lipase | -0.00341653 |
| PEG10 | paternally expressed 10 | -0.00341063 |
| RAB2A | RAB2A, member RAS oncogene family | -0.00340775 |
| CCL4 | chemokine (C-C motif) ligand 4 | -0.00340712 |
| CYP39A1 | cytochrome P450, family 39, subfamily A, polypeptide 1 | -0.00340365 |
| PID1 | phosphotyrosine interaction domain containing 1 | -0.00339454 |
| NTS | neurotensin | -0.00338607 |
| TSPO | translocator protein (18kDa) | -0.00338555 |
| PPFIBP2 | PTPRF interacting protein, binding protein 2 (liprin beta 2) | -0.00338423 |
| DPM3 | dolichyl-phosphate mannosyltransferase polypeptide 3 | -0.00338297 |
| PRRC2A | proline-rich coiled-coil 2A | -0.00337863 |
| TLE5 | TLE family member 5, transcriptional modulator | -0.00337359 |
| MGAM | maltase-glucoamylase | -0.00337314 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | -0.0033682 |
| COX6B1 | cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) | -0.00336301 |
| ING3 | inhibitor of growth family, member 3 | -0.00335697 |
| PAX5 | paired box 5 | -0.00335566 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | -0.00334613 |
| BCLAF1 | BCL2-associated transcription factor 1 | -0.0033429 |
| NUCB1 | nucleobindin 1 | -0.00333455 |
| MUC16 | mucin 16, cell surface associated | -0.00333231 |
| JAM3 | junctional adhesion molecule 3 | -0.00333034 |
| BCL2A1 | BCL2-related protein A1 | -0.00332443 |
| SKIV2L | superkiller viralicidic activity 2-like (S. cerevisiae) | -0.00332341 |
| TRIM28 | tripartite motif containing 28 | -0.00332291 |
| NCOA2 | nuclear receptor coactivator 2 | -0.00332237 |
| CSRP1 | cysteine and glycine-rich protein 1 | -0.00331887 |
| RIPOR2 | RHO family interacting cell polarization regulator 2 | -0.00331777 |
| TBC1D16 | TBC1 domain family, member 16 | -0.00331442 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | -0.00331152 |
| SOX10 | SRY (sex determining region Y)-box 10 | -0.00330932 |
| UGT2B17 | UDP glucuronosyltransferase 2 family, polypeptide B17 | -0.00329777 |
| CORO2B | coronin, actin binding protein, 2B | -0.00329449 |
| CTSB | cathepsin B | -0.00329196 |
| WASF3 | WAS protein family, member 3 | -0.0032883 |
| GNE | glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase | -0.00328734 |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 | -0.00328718 |
| ZBTB10 | zinc finger and BTB domain containing 10 | -0.00327898 |
| ZSCAN18 | zinc finger and SCAN domain containing 18 | -0.00327219 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.00327105 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.00327055 |
| PPP2R1B | protein phosphatase 2, regulatory subunit A, beta | -0.00325631 |
| HEBP2 | heme binding protein 2 | -0.00325585 |
| RBL2 | retinoblastoma-like 2 | -0.00325524 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.00325166 |
| POU2AF1 | POU class 2 associating factor 1 | -0.00324965 |
| HTRA1 | HtrA serine peptidase 1 | -0.00324469 |
| PJA1 | praja ring finger 1, E3 ubiquitin protein ligase | -0.00324273 |
