BAY-11-7085 Gene Set

Dataset LINCS L1000 CMAP Chemical Perturbation Consensus Signatures
Category transcriptomics
Type small molecule perturbation
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Genes

481 genes differentially expressed following the BAY-11-7085 small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
EGR1 early growth response 1 6.75828
KLF10 Kruppel-like factor 10 6.06529
F2RL1 coagulation factor II (thrombin) receptor-like 1 5.98374
IER5 immediate early response 5 5.69503
PHLDA2 pleckstrin homology-like domain, family A, member 2 5.65644
IER3 immediate early response 3 5.51314
GADD45B growth arrest and DNA-damage-inducible, beta 5.458
NAMPT nicotinamide phosphoribosyltransferase 5.45075
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 5.41627
FOSL1 FOS-like antigen 1 5.3453
MAP2K3 mitogen-activated protein kinase kinase 3 5.17094
TSC22D2 TSC22 domain family, member 2 5.14942
DUSP7 dual specificity phosphatase 7 5.04734
MYC v-myc avian myelocytomatosis viral oncogene homolog 5.0302
KLHL21 kelch-like family member 21 4.85587
SNRK SNF related kinase 4.84139
DUSP5 dual specificity phosphatase 5 4.81215
TRIB1 tribbles pseudokinase 1 4.80864
BCL10 B-cell CLL/lymphoma 10 4.80841
EHD4 EH-domain containing 4 4.7074
RAB11FIP5 RAB11 family interacting protein 5 (class I) 4.65028
PHLDA1 pleckstrin homology-like domain, family A, member 1 4.63341
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A 4.60743
MAP2K4 mitogen-activated protein kinase kinase 4 4.52706
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2 4.51369
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 4.50478
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G 4.5031
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 4.47673
NAA16 N(alpha)-acetyltransferase 16, NatA auxiliary subunit 4.46507
NR4A1 nuclear receptor subfamily 4, group A, member 1 4.46131
PNP purine nucleoside phosphorylase 4.42832
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae) 4.40601
PELI1 pellino E3 ubiquitin protein ligase 1 4.39132
CHD1 chromodomain helicase DNA binding protein 1 4.37536
AEN apoptosis enhancing nuclease 4.36568
INAVA innate immunity activator 4.35129
CHSY1 chondroitin sulfate synthase 1 4.34564
TOP1 topoisomerase (DNA) I 4.33463
UPP1 uridine phosphorylase 1 4.33381
PTPRE protein tyrosine phosphatase, receptor type, E 4.32059
YRDC yrdC N(6)-threonylcarbamoyltransferase domain containing 4.29238
ERG v-ets avian erythroblastosis virus E26 oncogene homolog 4.26368
PPP1R15A protein phosphatase 1, regulatory subunit 15A 4.25993
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1 4.25978
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 4.24305
EPHA2 EPH receptor A2 4.22405
IL1B interleukin 1, beta 4.21496
MIR22HG MIR22 host gene 4.17491
MEF2A myocyte enhancer factor 2A 4.17045
KCMF1 potassium channel modulatory factor 1 4.13005
HSPA6 heat shock 70kDa protein 6 (HSP70B') 4.10506
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 4.10405
TICAM1 toll-like receptor adaptor molecule 1 4.09979
RORA RAR-related orphan receptor A 4.09586
TPT1 tumor protein, translationally-controlled 1 4.09431
HECA headcase homolog (Drosophila) 4.08907
TUFT1 tuftelin 1 4.08683
SERTAD2 SERTA domain containing 2 4.0732
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 4.03237
OSBPL2 oxysterol binding protein-like 2 4.03174
CDK17 cyclin-dependent kinase 17 4.02897
PLAU plasminogen activator, urokinase 3.99105
JUNB jun B proto-oncogene 3.99081
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 3.98917
OCRL oculocerebrorenal syndrome of Lowe 3.98189
FGFBP1 fibroblast growth factor binding protein 1 3.97159
SMOX spermine oxidase 3.96753
GRPEL1 GrpE-like 1, mitochondrial (E. coli) 3.96585
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 3.96526
RAP2B RAP2B, member of RAS oncogene family 3.95723
SIK1 salt-inducible kinase 1 3.9348
NDEL1 nudE neurodevelopment protein 1-like 1 3.92683
JMJD1C jumonji domain containing 1C 3.86808
ZNF408 zinc finger protein 408 3.86492
FOSL2 FOS-like antigen 2 3.84255
SPRY4 sprouty homolog 4 (Drosophila) 3.84229
IL1A interleukin 1, alpha 3.84207
AHSP alpha hemoglobin stabilizing protein 3.82683
AGO2 argonaute RISC catalytic component 2 3.81912
PDGFA platelet-derived growth factor alpha polypeptide 3.8177
RPS27A ribosomal protein S27a 3.78195
ZNF593 zinc finger protein 593 3.77163
PLAUR plasminogen activator, urokinase receptor 3.76922
NR4A3 nuclear receptor subfamily 4, group A, member 3 3.75196
NUP58 nucleoporin 58 3.72842
HSPH1 heat shock 105kDa/110kDa protein 1 3.72752
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 3.723
BMAL1 basic helix-loop-helix ARNT like 1 3.71585
PAWR PRKC, apoptosis, WT1, regulator 3.71301
UCHL3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) 3.70991
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2 3.70824
LDLR low density lipoprotein receptor 3.68546
R3HDM4 R3H domain containing 4 3.68505
NOP2 NOP2 nucleolar protein 3.68211
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 3.67099
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 3.67092
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha 3.67021
KCNK1 potassium channel, two pore domain subfamily K, member 1 3.66941
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1 3.66419
RCL1 RNA terminal phosphate cyclase-like 1 3.65847
SH2B3 SH2B adaptor protein 3 3.64889
FBXL14 F-box and leucine-rich repeat protein 14 3.64746
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 3.63535
TRMT61A tRNA methyltransferase 61A 3.62812
ZNF473 zinc finger protein 473 3.62147
ADM adrenomedullin 3.58992
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae) 3.58325
MAST4 microtubule associated serine/threonine kinase family member 4 3.57963
TUT7 terminal uridylyl transferase 7 3.55419
ZNF189 zinc finger protein 189 3.54369
LONRF3 LON peptidase N-terminal domain and ring finger 3 3.54172
HBEGF heparin-binding EGF-like growth factor 3.53895
TXNRD1 thioredoxin reductase 1 3.53062
TSPYL1 TSPY-like 1 3.5246
IFRD1 interferon-related developmental regulator 1 3.51864
HMOX1 heme oxygenase 1 3.51662
GDF15 growth differentiation factor 15 3.51298
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 3.51172
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 3.50861
C3ORF52 chromosome 3 open reading frame 52 3.50601
PDLIM5 PDZ and LIM domain 5 3.48263
IER2 immediate early response 2 3.48224
GJB3 gap junction protein, beta 3, 31kDa 3.47845
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 3.45865
LIF leukemia inhibitory factor 3.4573
MAP3K13 mitogen-activated protein kinase kinase kinase 13 3.45452
ATG101 autophagy related 101 3.45391
AKIRIN1 akirin 1 3.44743
UGDH UDP-glucose 6-dehydrogenase 3.44602
EIF1AX eukaryotic translation initiation factor 1A, X-linked 3.43132
EPB42 erythrocyte membrane protein band 4.2 3.42851
CA6 carbonic anhydrase VI 3.42204
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 3.42159
SLC28A3 solute carrier family 28 (concentrative nucleoside transporter), member 3 3.41905
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1 3.41788
LGALS3 lectin, galactoside-binding, soluble, 3 3.41196
GLRX glutaredoxin (thioltransferase) 3.41006
PRDX2 peroxiredoxin 2 3.4092
GTPBP4 GTP binding protein 4 3.40897
WWTR1 WW domain containing transcription regulator 1 3.40635
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21 3.39586
FOS FBJ murine osteosarcoma viral oncogene homolog 3.39161
SLC66A2 solute carrier family 66 member 2 3.38389
GNL3 guanine nucleotide binding protein-like 3 (nucleolar) 3.37924
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2 3.37272
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase 3.37134
POLR1D polymerase (RNA) I polypeptide D, 16kDa 3.3694
CAPRIN2 caprin family member 2 3.3556
OTUD4 OTU deubiquitinase 4 3.34917
CLCF1 cardiotrophin-like cytokine factor 1 3.34301
OSBPL10 oxysterol binding protein-like 10 3.33857
PLK2 polo-like kinase 2 3.32114
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6 3.31222
GPR4 G protein-coupled receptor 4 3.29765
DUSP6 dual specificity phosphatase 6 3.29294
ARF6 ADP-ribosylation factor 6 3.29292
PRMT2IP PRMT2 interacting protein 3.28952
PRDM1 PR domain containing 1, with ZNF domain 3.28943
CHIC2 cysteine-rich hydrophobic domain 2 3.28878
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 3.27988
N4BP1 NEDD4 binding protein 1 3.27851
HYAL4 hyaluronoglucosaminidase 4 3.27811
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4 3.27736
POP7 processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae) 3.26754
MTMR9 myotubularin related protein 9 3.26595
THBD thrombomodulin 3.26299
DUSP8 dual specificity phosphatase 8 3.25666
NT5C2 5'-nucleotidase, cytosolic II 3.25604
AKAP17A A kinase (PRKA) anchor protein 17A 3.25561
EGR2 early growth response 2 3.25088
FOXO3 forkhead box O3 3.24466
ENOX1 ecto-NOX disulfide-thiol exchanger 1 3.23566
GEM GTP binding protein overexpressed in skeletal muscle 3.23202
SRPK1 SRSF protein kinase 1 3.23009
KDM6B lysine (K)-specific demethylase 6B 3.22372
NECAB2 N-terminal EF-hand calcium binding protein 2 3.22209
TSPAN14 tetraspanin 14 3.22171
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 3.21723
PLK3 polo-like kinase 3 3.21257
GPRASP1 G protein-coupled receptor associated sorting protein 1 3.21067
WDR43 WD repeat domain 43 3.20994
ALOXE3 arachidonate lipoxygenase 3 3.20692
NOP56 NOP56 ribonucleoprotein 3.19737
SNAI1 snail family zinc finger 1 3.18218
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa 3.18012
C1QTNF3 C1q and tumor necrosis factor related protein 3 3.1776
PRKRIP1 PRKR interacting protein 1 (IL11 inducible) 3.17603
RNF6 ring finger protein (C3H2C3 type) 6 3.17384
BCL2L1 BCL2-like 1 3.16021
ZNF696 zinc finger protein 696 3.15613
UQCRH ubiquinol-cytochrome c reductase hinge protein 3.1552
TWNK twinkle mtDNA helicase 3.1536
RUNDC3B RUN domain containing 3B 3.14685
SYT1 synaptotagmin I 3.1436
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 3.13419
JAG1 jagged 1 3.13096
BYSL bystin-like 3.11794
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 3.11691
MED17 mediator complex subunit 17 3.11545
SLC25A32 solute carrier family 25 (mitochondrial folate carrier), member 32 3.1127
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D 3.11134
CD93 CD93 molecule 3.1101
ANXA5 annexin A5 3.10747
PLXNA2 plexin A2 3.10169
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae) 3.10086
CBLL1 Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase 3.09675
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A 3.09468
ALKBH1 alkB, alkylation repair homolog 1 (E. coli) 3.09194
CDR2 cerebellar degeneration-related protein 2, 62kDa 3.08816
CREB5 cAMP responsive element binding protein 5 3.08676
TIGAR TP53 induced glycolysis regulatory phosphatase 3.08575
ISCA1 iron-sulfur cluster assembly 1 3.08504
DMTN dematin actin binding protein 3.08503
AIRE autoimmune regulator 3.07982
FKBP11 FK506 binding protein 11, 19 kDa 3.0748
ZNF143 zinc finger protein 143 3.06821
CAVIN3 caveolae associated protein 3 3.06548
AVPI1 arginine vasopressin-induced 1 3.05145
ARHGAP26 Rho GTPase activating protein 26 3.04838
ZNF710 zinc finger protein 710 3.04361
BIN3 bridging integrator 3 3.04011
TGFA transforming growth factor, alpha 3.03843
TFB2M transcription factor B2, mitochondrial 3.03829
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 3.03189
DDA1 DET1 and DDB1 associated 1 3.03046
SNCA synuclein, alpha (non A4 component of amyloid precursor) 3.02674
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B 3.02246
GFPT1 glutamine--fructose-6-phosphate transaminase 1 3.02012
SKIL SKI-like proto-oncogene 3.01796
ZNF8 zinc finger protein 8 3.0167
NOP14 NOP14 nucleolar protein 3.01329
MCL1 myeloid cell leukemia 1 3.01224
PMS2P3 postmeiotic segregation increased 2 pseudogene 3 3.00765
DOCK4 dedicator of cytokinesis 4 3.00333
EGR3 early growth response 3 3.00295

decreased expression

Symbol Name Standardized Value
TPX2 TPX2, microtubule-associated -6.72781
RAB13 RAB13, member RAS oncogene family -5.15627
CENPF centromere protein F, 350/400kDa -4.94185
KIF20A kinesin family member 20A -4.81645
LMNB1 lamin B1 -4.75113
TAFAZZIN tafazzin, phospholipid-lysophospholipid transacylase -4.75113
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B -4.74039
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -4.73174
BUB1 BUB1 mitotic checkpoint serine/threonine kinase -4.71411
PSRC1 proline/serine-rich coiled-coil 1 -4.67077
ZMYM3 zinc finger, MYM-type 3 -4.67019
PCDHGB6 protocadherin gamma subfamily B, 6 -4.65165
PRORP protein only RNase P catalytic subunit -4.59167
COG4 component of oligomeric golgi complex 4 -4.54507
IGFBP5 insulin-like growth factor binding protein 5 -4.44459
NAA11 N(alpha)-acetyltransferase 11, NatA catalytic subunit -4.43058
CDCA8 cell division cycle associated 8 -4.38848
UFSP2 UFM1-specific peptidase 2 -4.3617
NTS neurotensin -4.34698
HAUS4 HAUS augmin-like complex, subunit 4 -4.32046
PIWIL1 piwi-like RNA-mediated gene silencing 1 -4.25535
SPAG7 sperm associated antigen 7 -4.24538
BIRC5 baculoviral IAP repeat containing 5 -4.21542
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5 -4.20622
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae) -4.17857
ACTR1B ARP1 actin-related protein 1 homolog B, centractin beta (yeast) -4.16441
HLTF helicase-like transcription factor -4.1581
PROS1 protein S (alpha) -4.13083
COA1 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) -4.08294
HMGCL 3-hydroxymethyl-3-methylglutaryl-CoA lyase -4.08041
H2BC17 H2B clustered histone 17 -4.06337
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) -4.06171
BRD3OS BRD3 opposite strand -4.03786
PCDHA2 protocadherin alpha 2 -4.03468
IK IK cytokine, down-regulator of HLA II -4.01268
KIFC1 kinesin family member C1 -4.00508
CEP250 centrosomal protein 250kDa -3.99586
FASTK Fas-activated serine/threonine kinase -3.99127
GSTM4 glutathione S-transferase mu 4 -3.9862
TROAP trophinin associated protein -3.98252
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 -3.9444
HMGB3 high mobility group box 3 -3.94342
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 -3.94169
SH2D2A SH2 domain containing 2A -3.90466
KDM1A lysine (K)-specific demethylase 1A -3.90214
DNM1 dynamin 1 -3.89624
TOP2A topoisomerase (DNA) II alpha 170kDa -3.88776
CNTRL centriolin -3.86575
B4GAT1 beta-1,4-glucuronyltransferase 1 -3.86342
PDHB pyruvate dehydrogenase (lipoamide) beta -3.85853
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) -3.84367
NR1H3 nuclear receptor subfamily 1, group H, member 3 -3.82272
SNX13 sorting nexin 13 -3.79965
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6 -3.78944
SCN9A sodium channel, voltage gated, type IX alpha subunit -3.7797
THYN1 thymocyte nuclear protein 1 -3.77439
VPS35L VPS35 endosomal protein sorting factor like -3.76068
KIF11 kinesin family member 11 -3.75215
KIF15 kinesin family member 15 -3.74978
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit -3.73575
GATD3 glutamine amidotransferase class 1 domain containing 3 -3.72871
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3 -3.72403
CCHCR1 coiled-coil alpha-helical rod protein 1 -3.71549
USP21 ubiquitin specific peptidase 21 -3.70984
AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1 -3.70724
PHF10 PHD finger protein 10 -3.70245
CAND2 cullin-associated and neddylation-dissociated 2 (putative) -3.67646
PFDN5 prefoldin subunit 5 -3.67402
FUZ fuzzy planar cell polarity protein -3.66249
H2AC13 H2A clustered histone 13 -3.65108
H2BC9 H2B clustered histone 9 -3.64753
ARHGAP11A Rho GTPase activating protein 11A -3.64612
RNF32 ring finger protein 32 -3.63979
ACTMAP actin maturation protease -3.6378
GLT8D1 glycosyltransferase 8 domain containing 1 -3.63566
MSX2 msh homeobox 2 -3.62285
ICMT isoprenylcysteine carboxyl methyltransferase -3.62253
ANXA6 annexin A6 -3.61756
NAGA N-acetylgalactosaminidase, alpha- -3.6156
SPAG5 sperm associated antigen 5 -3.60802
MAGED2 melanoma antigen family D2 -3.60066
GAGE1 G antigen 1 -3.59334
MPL MPL proto-oncogene, thrombopoietin receptor -3.5792
DGLUCY D-glutamate cyclase -3.57715
CLEC4M C-type lectin domain family 4, member M -3.57339
HARS2 histidyl-tRNA synthetase 2, mitochondrial -3.56611
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase -3.53914
UXT ubiquitously-expressed, prefoldin-like chaperone -3.535
C14ORF93 chromosome 14 open reading frame 93 -3.53497
ECH1 enoyl CoA hydratase 1, peroxisomal -3.53365
H1-5 H1.5 linker histone, cluster member -3.53053
ERCC5 excision repair cross-complementation group 5 -3.5293
NIPSNAP2 nipsnap homolog 2 -3.52555
DCAF1 DDB1 and CUL4 associated factor 1 -3.52392
MARCHF1 membrane associated ring-CH-type finger 1 -3.52121
GSTK1 glutathione S-transferase kappa 1 -3.51813
IRAK4 interleukin-1 receptor-associated kinase 4 -3.51622
CDCA3 cell division cycle associated 3 -3.50658
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2 -3.50245
PEF1 penta-EF-hand domain containing 1 -3.49125
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1 -3.4901
HPF1 histone PARylation factor 1 -3.48972
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -3.48952
ZBED5 zinc finger, BED-type containing 5 -3.48096
MRTFB myocardin related transcription factor B -3.47854
UNC13B unc-13 homolog B (C. elegans) -3.47729
PEX19 peroxisomal biogenesis factor 19 -3.47299
RPA2 replication protein A2, 32kDa -3.47088
H2BC3 H2B clustered histone 3 -3.47054
OLFM1 olfactomedin 1 -3.4575
REPIN1 replication initiator 1 -3.45484
TBC1D5 TBC1 domain family, member 5 -3.4505
PDS5A PDS5 cohesin associated factor A -3.45036
TYMS thymidylate synthetase -3.44478
MXD3 MAX dimerization protein 3 -3.43604
GALT galactose-1-phosphate uridylyltransferase -3.43457
KIF4A kinesin family member 4A -3.42709
SSB Sjogren syndrome antigen B (autoantigen La) -3.41708
HSDL2 hydroxysteroid dehydrogenase like 2 -3.41468
LARP7 La ribonucleoprotein domain family, member 7 -3.4119
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 -3.40874
LRRC31 leucine rich repeat containing 31 -3.39947
NFS1 NFS1 cysteine desulfurase -3.39552
LINC00588 long intergenic non-protein coding RNA 588 -3.39471
GRIK2 glutamate receptor, ionotropic, kainate 2 -3.38793
PRSS21 protease, serine, 21 (testisin) -3.37638
TSPO translocator protein (18kDa) -3.37498
FOXL2 forkhead box L2 -3.37142
TBCB tubulin folding cofactor B -3.37112
H2BC14 H2B clustered histone 14 -3.36866
NEK1 NIMA-related kinase 1 -3.36681
SNX17 sorting nexin 17 -3.36199
COQ3 coenzyme Q3 methyltransferase -3.3614
KDM3B lysine (K)-specific demethylase 3B -3.36053
ECI2 enoyl-CoA delta isomerase 2 -3.35291
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein -3.35034
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide -3.3483
POLA2 polymerase (DNA directed), alpha 2, accessory subunit -3.34273
EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa -3.34018
METTL17 methyltransferase like 17 -3.3336
DPY19L1 dpy-19-like 1 (C. elegans) -3.32532
LIG1 ligase I, DNA, ATP-dependent -3.32498
ELP4 elongator acetyltransferase complex subunit 4 -3.31758
PPA2 pyrophosphatase (inorganic) 2 -3.31101
NDUFA10 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa -3.30924
NUDCD3 NudC domain containing 3 -3.29909
FAM3A family with sequence similarity 3, member A -3.29675
VAMP4 vesicle-associated membrane protein 4 -3.29295
FBN1 fibrillin 1 -3.28611
MEP1B meprin A, beta -3.28371
MAP2K6 mitogen-activated protein kinase kinase 6 -3.28331
HMMR hyaluronan-mediated motility receptor (RHAMM) -3.27769
USP49 ubiquitin specific peptidase 49 -3.27633
FKBP9 FK506 binding protein 9, 63 kDa -3.27465
ZNF80 zinc finger protein 80 -3.27321
HTATSF1 HIV-1 Tat specific factor 1 -3.27225
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae) -3.27148
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G -3.26974
UBE2I ubiquitin-conjugating enzyme E2I -3.26956
CCNB1 cyclin B1 -3.25997
ACAD10 acyl-CoA dehydrogenase family, member 10 -3.25604
MAGEA8 melanoma antigen family A8 -3.25469
SLC35E2B solute carrier family 35, member E2B -3.24889
RMND5B required for meiotic nuclear division 5 homolog B (S. cerevisiae) -3.24751
CFAP68 cilia and flagella associated protein 68 -3.24403
ARHGAP28 Rho GTPase activating protein 28 -3.23951
CDH17 cadherin 17, LI cadherin (liver-intestine) -3.23565
SAGE1 sarcoma antigen 1 -3.23372
ETFB electron-transfer-flavoprotein, beta polypeptide -3.22489
CLEC2B C-type lectin domain family 2, member B -3.22276
ECI1 enoyl-CoA delta isomerase 1 -3.21082
VPS45 vacuolar protein sorting 45 homolog (S. cerevisiae) -3.21008
DCTN2 dynactin 2 (p50) -3.20757
MAP3K12 mitogen-activated protein kinase kinase kinase 12 -3.2063
ENTREP3 endosomal transmembrane epsin interactor 3 -3.20266
PTTG1 pituitary tumor-transforming 1 -3.19597
IL12B interleukin 12B -3.19326
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 -3.18933
SEPTIN11 septin 11 -3.18672
ZNF702P zinc finger protein 702, pseudogene -3.18552
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial -3.18415
DEPDC1 DEP domain containing 1 -3.18073
TNNT1 troponin T type 1 (skeletal, slow) -3.17606
EXOC2 exocyst complex component 2 -3.17266
PSG5 pregnancy specific beta-1-glycoprotein 5 -3.1721
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1 -3.17058
H1-2 H1.2 linker histone, cluster member -3.16572
DDHD2 DDHD domain containing 2 -3.16356
TMEM39B transmembrane protein 39B -3.16261
DDX23 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 -3.1578
VBP1 von Hippel-Lindau binding protein 1 -3.15478
NCAPH non-SMC condensin I complex, subunit H -3.15148
MED1 mediator complex subunit 1 -3.15123
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 -3.15024
CPS1 carbamoyl-phosphate synthase 1, mitochondrial -3.14598
CD72 CD72 molecule -3.1411
TASOR transcription activation suppressor -3.13921
ADAM28 ADAM metallopeptidase domain 28 -3.12764
TSC2 tuberous sclerosis 2 -3.1254
C1QB complement component 1, q subcomponent, B chain -3.11051
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) -3.10688
MKS1 Meckel syndrome, type 1 -3.10615
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae) -3.10214
PTPRF protein tyrosine phosphatase, receptor type, F -3.09858
GPR63 G protein-coupled receptor 63 -3.09674
C2 complement component 2 -3.09672
ALCAM activated leukocyte cell adhesion molecule -3.09186
H2BC21 H2B clustered histone 21 -3.09104
FANCA Fanconi anemia, complementation group A -3.0894
CCS copper chaperone for superoxide dismutase -3.0894
FAM114A1 family with sequence similarity 114, member A1 -3.08517
MAPKAP1 mitogen-activated protein kinase associated protein 1 -3.07667
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12 -3.07639
MARCO macrophage receptor with collagenous structure -3.07515
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 -3.07387
GBE1 glucan (1,4-alpha-), branching enzyme 1 -3.06857
ATAD5 ATPase family, AAA domain containing 5 -3.067
COL1A1 collagen, type I, alpha 1 -3.06651
ISYNA1 inositol-3-phosphate synthase 1 -3.06218
DNAL4 dynein, axonemal, light chain 4 -3.05991
IGFBP4 insulin-like growth factor binding protein 4 -3.05886
SLC6A16 solute carrier family 6, member 16 -3.05607
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha -3.05404
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1 -3.05384
SPC25 SPC25, NDC80 kinetochore complex component -3.05383
ZNF214 zinc finger protein 214 -3.05184
POLR1F RNA polymerase I subunit F -3.0486
WNT2B wingless-type MMTV integration site family, member 2B -3.04289
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) -3.04178
CDK5 cyclin-dependent kinase 5 -3.04177
DCTN3 dynactin 3 (p22) -3.04111
SPO11 SPO11 meiotic protein covalently bound to DSB -3.03582
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 -3.03028
H1-4 H1.4 linker histone, cluster member -3.0302
NDUFB2 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa -3.0274
GTSE1 G-2 and S-phase expressed 1 -3.02693
ACSM3 acyl-CoA synthetase medium-chain family member 3 -3.01829
NF1 neurofibromin 1 -3.01803
IMPG2 interphotoreceptor matrix proteoglycan 2 -3.01403
CD226 CD226 molecule -3.01224
CCDC71 coiled-coil domain containing 71 -3.01176
TAS2R14 taste receptor, type 2, member 14 -3.01107
GSE1 Gse1 coiled-coil protein -3.01034
ZDHHC3 zinc finger, DHHC-type containing 3 -3.00983
PTPRC protein tyrosine phosphatase, receptor type, C -3.00719
GRHPR glyoxylate reductase/hydroxypyruvate reductase -3.00531