| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | BAY1125976 perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the BAY1125976_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.220433 |
| LCN2 | lipocalin 2 | 0.15621 |
| B2M | beta-2-microglobulin | 0.14578 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.110023 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.107099 |
| RNF213 | ring finger protein 213 | 0.101548 |
| SMAD3 | SMAD family member 3 | 0.098018 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0927485 |
| FTL | ferritin, light polypeptide | 0.0865588 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0862166 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0837874 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0799145 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0717668 |
| ENO1 | enolase 1, (alpha) | 0.0703805 |
| ASPH | aspartate beta-hydroxylase | 0.0703022 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0694591 |
| PKM | pyruvate kinase, muscle | 0.0680887 |
| PTMA | prothymosin, alpha | 0.0676908 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0611634 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0608861 |
| AREG | amphiregulin | 0.0600064 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0592142 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0585503 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.057431 |
| RPL23 | ribosomal protein L23 | 0.0535031 |
| HKDC1 | hexokinase domain containing 1 | 0.0534222 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0518553 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0506939 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0496913 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.049365 |
| TMSB10 | thymosin beta 10 | 0.0488769 |
| DST | dystonin | 0.0484577 |
| KYNU | kynureninase | 0.0477842 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0477554 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | 0.0473239 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.046765 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.046715 |
| MAP7 | microtubule-associated protein 7 | 0.0460317 |
| ACTG1 | actin gamma 1 | 0.0459371 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0459349 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0448585 |
| RPS6 | ribosomal protein S6 | 0.0444457 |
| INTS6 | integrator complex subunit 6 | 0.0440913 |
| HLA-B | major histocompatibility complex, class I, B | 0.0440633 |
| TJP1 | tight junction protein 1 | 0.0438794 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0429188 |
| SP100 | SP100 nuclear antigen | 0.0422428 |
| TMC5 | transmembrane channel-like 5 | 0.0418903 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0405027 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0404421 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0400517 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0398864 |
| SIK3 | SIK family kinase 3 | 0.039737 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0395841 |
| MX2 | MX dynamin-like GTPase 2 | 0.0393989 |
| C6ORF132 | chromosome 6 open reading frame 132 | 0.0391365 |
| RPS3 | ribosomal protein S3 | 0.0383428 |
| TPI1 | triosephosphate isomerase 1 | 0.038321 |
| MT2A | metallothionein 2A | 0.0382753 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0377827 |
| PERP | PERP, TP53 apoptosis effector | 0.0377424 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0375865 |
| RPS8 | ribosomal protein S8 | 0.0375105 |
| RPL7L1 | ribosomal protein L7-like 1 | 0.0374556 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0373642 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0373454 |
| MYO1E | myosin IE | 0.0373383 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0367742 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.0365692 |
| HLA-A | major histocompatibility complex, class I, A | 0.0352309 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0343691 |
| SEPTIN9 | septin 9 | 0.0342602 |
| MCU | mitochondrial calcium uniporter | 0.0341135 |
| RPL37A | ribosomal protein L37a | 0.0340921 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.034054 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0336469 |
| RPS19 | ribosomal protein S19 | 0.0334752 |
| RPL26 | ribosomal protein L26 | 0.0333833 |
| EFNB2 | ephrin-B2 | 0.0332279 |
| MUC20 | mucin 20, cell surface associated | 0.03285 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0326559 |
| FNIP2 | folliculin interacting protein 2 | 0.032645 |
| RPL19 | ribosomal protein L19 | 0.0326407 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0326357 |
| PGK1 | phosphoglycerate kinase 1 | 0.0325039 |
| ANXA2 | annexin A2 | 0.0314633 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.031389 |
| SQSTM1 | sequestosome 1 | 0.0313225 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0312391 |
| RPS17 | ribosomal protein S17 | 0.0311896 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0310182 |
| HLA-E | major histocompatibility complex, class I, E | 0.0304696 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0303591 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0303571 |
| RPS27 | ribosomal protein S27 | 0.0301404 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0300575 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0300055 |
| LDHA | lactate dehydrogenase A | 0.0300002 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0299083 |
| KRT18 | keratin 18, type I | 0.0297253 |
| Symbol | Name | Standardized Value |
|---|---|---|
| BTBD9 | BTB (POZ) domain containing 9 | -0.0638099 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0623157 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0541149 |
| RNF43 | ring finger protein 43 | -0.0512051 |
| TXNIP | thioredoxin interacting protein | -0.0481595 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0471818 |
| PTEN | phosphatase and tensin homolog | -0.0440157 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0391447 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0364605 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.033965 |
| DIAPH3 | diaphanous-related formin 3 | -0.0334902 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0321714 |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked | -0.0304227 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0301808 |
| NDRG1 | N-myc downstream regulated 1 | -0.0286759 |
| RUNX1 | runt-related transcription factor 1 | -0.0285326 |
| UBAC2 | UBA domain containing 2 | -0.0276518 |
| ZDHHC20 | zinc finger, DHHC-type containing 20 | -0.0276475 |
| RBM39 | RNA binding motif protein 39 | -0.02761 |
| COG6 | component of oligomeric golgi complex 6 | -0.0275092 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0266026 |
| CCNL1 | cyclin L1 | -0.0265349 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0255123 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0251273 |
| MCTP2 | multiple C2 domains, transmembrane 2 | -0.0250166 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0246481 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0241863 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.0237108 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0236635 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0234135 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0224101 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.0221649 |
| RNF149 | ring finger protein 149 | -0.021713 |
| GRAMD2B | GRAM domain containing 2B | -0.0211613 |
| TMEM62 | transmembrane protein 62 | -0.0209957 |
| PRELID2 | PRELI domain containing 2 | -0.0207791 |
| EHF | ets homologous factor | -0.0205677 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0202008 |
| GRK3 | G protein-coupled receptor kinase 3 | -0.0200451 |
| BCLAF1 | BCL2-associated transcription factor 1 | -0.0196704 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0194735 |
| ZNRF3 | zinc and ring finger 3 | -0.019416 |
| METTL15 | methyltransferase like 15 | -0.0193831 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0193215 |
| H1-0 | H1.0 linker histone | -0.0192735 |
| SCARB1 | scavenger receptor class B, member 1 | -0.019045 |
| RAD51B | RAD51 paralog B | -0.0188744 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0187096 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0186623 |
| TC2N | tandem C2 domains, nuclear | -0.0185995 |
| PLSCR1 | phospholipid scramblase 1 | -0.0184962 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0184458 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0181865 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0179501 |
| SBF2 | SET binding factor 2 | -0.0176824 |
| TMPRSS4 | transmembrane protease, serine 4 | -0.0175168 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0173738 |
| CDC42SE2 | CDC42 small effector 2 | -0.0172772 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0171625 |
| AHI1 | Abelson helper integration site 1 | -0.017109 |
| SPG11 | spastic paraplegia 11 (autosomal recessive) | -0.0168971 |
| USP3 | ubiquitin specific peptidase 3 | -0.0168133 |
| IFT88 | intraflagellar transport 88 | -0.0167495 |
| NPSR1 | neuropeptide S receptor 1 | -0.0166535 |
| BRCA2 | breast cancer 2, early onset | -0.0165947 |
| MECOM | MDS1 and EVI1 complex locus | -0.0165753 |
| HDAC4 | histone deacetylase 4 | -0.0164859 |
| USPL1 | ubiquitin specific peptidase like 1 | -0.0164089 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | -0.0163943 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.016084 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0160537 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0160159 |
| MKI67 | marker of proliferation Ki-67 | -0.0158379 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0157707 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0157363 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0157076 |
| HELZ | helicase with zinc finger | -0.0154331 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0154079 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.0153134 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0152181 |
| RAD54B | RAD54 homolog B (S. cerevisiae) | -0.0151533 |
| NCKAP5 | NCK-associated protein 5 | -0.0151487 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0150856 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0149807 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.014826 |
| ETNK1 | ethanolamine kinase 1 | -0.0147962 |
| SEC24D | SEC24 family member D | -0.014767 |
| HBS1L | HBS1-like translational GTPase | -0.0147062 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0146309 |
| TMEM263 | transmembrane protein 263 | -0.0145833 |
| TUBGCP3 | tubulin, gamma complex associated protein 3 | -0.0144764 |
| TMEM39A | transmembrane protein 39A | -0.0144344 |
| NCOA2 | nuclear receptor coactivator 2 | -0.0143666 |
| MEF2A | myocyte enhancer factor 2A | -0.0141241 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0140727 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0140727 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | -0.0140253 |
| IL20RA | interleukin 20 receptor, alpha | -0.0139427 |
| CLYBL | citrate lyase beta like | -0.0139129 |
| TNS4 | tensin 4 | -0.01381 |
