| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | BAY1125976 perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the BAY1125976_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.271911 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.141239 |
| MT2A | metallothionein 2A | 0.135274 |
| VIM | vimentin | 0.127534 |
| FN1 | fibronectin 1 | 0.117877 |
| ENO1 | enolase 1, (alpha) | 0.107437 |
| CALR | calreticulin | 0.0938275 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0873518 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0821903 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0716627 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0672949 |
| PLEC | plectin | 0.0664987 |
| LDHA | lactate dehydrogenase A | 0.0629844 |
| TMSB10 | thymosin beta 10 | 0.0589222 |
| ASPH | aspartate beta-hydroxylase | 0.0532727 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0513131 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0510663 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0494298 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0453296 |
| HYOU1 | hypoxia up-regulated 1 | 0.0428656 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0424983 |
| RPL3 | ribosomal protein L3 | 0.0411759 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0402473 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0399712 |
| PKM | pyruvate kinase, muscle | 0.0374152 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.037392 |
| GOLGB1 | golgin B1 | 0.0369148 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0367835 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0365437 |
| RPL23 | ribosomal protein L23 | 0.0364338 |
| B2M | beta-2-microglobulin | 0.0337721 |
| RPL7 | ribosomal protein L7 | 0.0335271 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0335123 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0334606 |
| RPS3 | ribosomal protein S3 | 0.0324725 |
| TPI1 | triosephosphate isomerase 1 | 0.0324674 |
| RPL26 | ribosomal protein L26 | 0.0322895 |
| ANGPTL4 | angiopoietin-like 4 | 0.0320769 |
| RPS8 | ribosomal protein S8 | 0.0317786 |
| BRD2 | bromodomain containing 2 | 0.0317472 |
| RPS19 | ribosomal protein S19 | 0.0310729 |
| POSTN | periostin, osteoblast specific factor | 0.0307083 |
| SP100 | SP100 nuclear antigen | 0.0298906 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0298507 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0291598 |
| EXT1 | exostosin glycosyltransferase 1 | 0.028799 |
| TMSB4X | thymosin beta 4, X-linked | 0.0286203 |
| RACK1 | receptor for activated C kinase 1 | 0.0270276 |
| FAM107B | family with sequence similarity 107, member B | 0.026764 |
| RPS12 | ribosomal protein S12 | 0.0262635 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0258727 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0257503 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0253125 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0251978 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0246235 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0245613 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0243028 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0239776 |
| HDAC9 | histone deacetylase 9 | 0.0239428 |
| RPL19 | ribosomal protein L19 | 0.0239339 |
| CALU | calumenin | 0.0237879 |
| TPM3 | tropomyosin 3 | 0.0237719 |
| CANX | calnexin | 0.0237477 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0235705 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0234298 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0233952 |
| DSPP | dentin sialophosphoprotein | 0.023234 |
| RPL36 | ribosomal protein L36 | 0.0230655 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0229677 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.022651 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.022276 |
| RPL13A | ribosomal protein L13a | 0.0220083 |
| VCL | vinculin | 0.0215946 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0215589 |
| APP | amyloid beta (A4) precursor protein | 0.0214311 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.021366 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0213318 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0212862 |
| CSF1 | colony stimulating factor 1 (macrophage) | 0.0211824 |
| RPS17 | ribosomal protein S17 | 0.0209149 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0207892 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0207487 |
| COL3A1 | collagen, type III, alpha 1 | 0.0207194 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0204924 |
| MSN | moesin | 0.0203363 |
| RPLP2 | ribosomal protein, large, P2 | 0.0203184 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0202412 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0199986 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0198176 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0198089 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0194937 |
| RCN1 | reticulocalbin 1, EF-hand calcium binding domain | 0.0194191 |
| SON | SON DNA binding protein | 0.0193755 |
| SKP1 | S-phase kinase-associated protein 1 | 0.0192497 |
| RPL4 | ribosomal protein L4 | 0.0190984 |
| SQSTM1 | sequestosome 1 | 0.0189522 |
| RPL31 | ribosomal protein L31 | 0.0189443 |
| TPM2 | tropomyosin 2 (beta) | 0.0186498 |
| HDLBP | high density lipoprotein binding protein | 0.0184187 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0183403 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.35443 |
| NDRG1 | N-myc downstream regulated 1 | -0.326128 |
| COL1A1 | collagen, type I, alpha 1 | -0.102797 |
| CADM1 | cell adhesion molecule 1 | -0.0888542 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0829964 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0779226 |
| CDH13 | cadherin 13 | -0.0763986 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0704241 |
| ATP13A3 | ATPase type 13A3 | -0.0658088 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0656361 |
| PDE10A | phosphodiesterase 10A | -0.0609809 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0588204 |
| COL6A3 | collagen, type VI, alpha 3 | -0.047713 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0468421 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0458107 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0424984 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0410107 |
| QKI | QKI, KH domain containing, RNA binding | -0.0400242 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0394497 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | -0.0393113 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0389805 |
| ZNF292 | zinc finger protein 292 | -0.0385223 |
| COL1A2 | collagen, type I, alpha 2 | -0.0384815 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0381751 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0357113 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0343905 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0342007 |
| CLMP | CXADR-like membrane protein | -0.0327455 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0326574 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0325055 |
| USP3 | ubiquitin specific peptidase 3 | -0.0314342 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0311136 |
| HMGA2 | high mobility group AT-hook 2 | -0.0309989 |
| RLF | rearranged L-myc fusion | -0.0306094 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0305343 |
| IER3 | immediate early response 3 | -0.0302381 |
| LOXL2 | lysyl oxidase-like 2 | -0.0300635 |
| SNX9 | sorting nexin 9 | -0.0296655 |
| FMNL2 | formin-like 2 | -0.0295466 |
| SPAG9 | sperm associated antigen 9 | -0.0294523 |
| PTK2 | protein tyrosine kinase 2 | -0.0294092 |
| TMEM165 | transmembrane protein 165 | -0.0293965 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.029225 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.029109 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0290462 |
| TRAM1 | translocation associated membrane protein 1 | -0.0288296 |
| CD109 | CD109 molecule | -0.0282768 |
| RUNX1 | runt-related transcription factor 1 | -0.0279621 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0278044 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.02739 |
| MTSS1 | metastasis suppressor 1 | -0.0271564 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0271254 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.027026 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.026991 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0268406 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0265492 |
| MEDAG | mesenteric estrogen-dependent adipogenesis | -0.0263002 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0259031 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0258071 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0256225 |
| KIF13A | kinesin family member 13A | -0.0254014 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.02516 |
| RTN4 | reticulon 4 | -0.0248802 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0248787 |
| GOLGA4 | golgin A4 | -0.0244606 |
| TRAM2 | translocation associated membrane protein 2 | -0.0242146 |
| SKIC3 | SKI3 subunit of superkiller complex | -0.0240417 |
| BBX | bobby sox homolog (Drosophila) | -0.0240383 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0234475 |
| MTDH | metadherin | -0.0233502 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.023314 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0227645 |
| NAV2 | neuron navigator 2 | -0.0226874 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.0226424 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0225596 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0221103 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0220996 |
| KCTD9 | potassium channel tetramerization domain containing 9 | -0.0220576 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0220176 |
| FOXJ3 | forkhead box J3 | -0.0219359 |
| INHBA | inhibin, beta A | -0.0219161 |
| MMP3 | matrix metallopeptidase 3 | -0.0216735 |
| RBM39 | RNA binding motif protein 39 | -0.0215498 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0214861 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.0213562 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.02133 |
| EHD2 | EH-domain containing 2 | -0.0210849 |
| SBF2 | SET binding factor 2 | -0.0209136 |
| UBC | ubiquitin C | -0.0207632 |
| PRR16 | proline rich 16 | -0.0204639 |
| CCNL1 | cyclin L1 | -0.0203896 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0202513 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0201628 |
| HELZ | helicase with zinc finger | -0.0200717 |
| MT1X | metallothionein 1X | -0.0197942 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0197133 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0195667 |
| HOOK2 | hook microtubule-tethering protein 2 | -0.0195376 |
| GRB10 | growth factor receptor-bound protein 10 | -0.019467 |
| HIP1 | huntingtin interacting protein 1 | -0.0191022 |
