| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | BAY1125976 perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the BAY1125976_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.249821 |
| VIM | vimentin | 0.152863 |
| FN1 | fibronectin 1 | 0.112227 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0975764 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0964852 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0940672 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0909325 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0902842 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0885886 |
| ENO1 | enolase 1, (alpha) | 0.0865528 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0849667 |
| STC1 | stanniocalcin 1 | 0.0838796 |
| ANGPTL4 | angiopoietin-like 4 | 0.0838264 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0778527 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0775465 |
| CD44 | CD44 molecule (Indian blood group) | 0.0775172 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0717488 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0707093 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0705133 |
| PKM | pyruvate kinase, muscle | 0.0689005 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0668579 |
| AADAC | arylacetamide deacetylase | 0.0666745 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0659535 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0634947 |
| LOX | lysyl oxidase | 0.0608814 |
| LDHA | lactate dehydrogenase A | 0.0590462 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0584403 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0580929 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0574285 |
| SEPTIN9 | septin 9 | 0.0570883 |
| NTN4 | netrin 4 | 0.0562059 |
| ASPH | aspartate beta-hydroxylase | 0.0557785 |
| B2M | beta-2-microglobulin | 0.0549892 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0547696 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0543933 |
| CDH13 | cadherin 13 | 0.053702 |
| MYO10 | myosin X | 0.0518928 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0498589 |
| ECE1 | endothelin converting enzyme 1 | 0.0494845 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0489388 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0486968 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0475413 |
| MT2A | metallothionein 2A | 0.0468045 |
| TMSB4X | thymosin beta 4, X-linked | 0.0465768 |
| CA12 | carbonic anhydrase XII | 0.0464699 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0454246 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0444008 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0441506 |
| NAV2 | neuron navigator 2 | 0.0440971 |
| SQSTM1 | sequestosome 1 | 0.0423498 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0421459 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0420591 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0415325 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0414158 |
| DST | dystonin | 0.0413915 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0408099 |
| INTS6 | integrator complex subunit 6 | 0.0407852 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0404428 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.0402472 |
| PRSS23 | protease, serine, 23 | 0.0402103 |
| HMGA2 | high mobility group AT-hook 2 | 0.0389934 |
| PLIN2 | perilipin 2 | 0.038769 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0372937 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0371597 |
| SP100 | SP100 nuclear antigen | 0.0366734 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0365597 |
| FBN1 | fibrillin 1 | 0.0364914 |
| AHNAK | AHNAK nucleoprotein | 0.0364676 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0364242 |
| RPL3 | ribosomal protein L3 | 0.0363661 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0363209 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0352872 |
| MTSS1 | metastasis suppressor 1 | 0.0347373 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0346079 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0345342 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0341143 |
| TGFB1 | transforming growth factor, beta 1 | 0.0338202 |
| FAM107B | family with sequence similarity 107, member B | 0.0337262 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0336423 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.0332988 |
| RPL4 | ribosomal protein L4 | 0.0331091 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0324199 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0323793 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0321354 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0320907 |
| PLEC | plectin | 0.0320375 |
| RPS6 | ribosomal protein S6 | 0.0317862 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0317049 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0314399 |
| SFTPA2 | surfactant protein A2 | 0.031191 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0311709 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0309068 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0307056 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.0299143 |
| SMAD3 | SMAD family member 3 | 0.0296048 |
| RPS8 | ribosomal protein S8 | 0.029592 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0295684 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0293125 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0292029 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0287181 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | -0.185746 |
| OSMR | oncostatin M receptor | -0.0816026 |
| RBM39 | RNA binding motif protein 39 | -0.076623 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0687174 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0674122 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0624399 |
| GOLGA4 | golgin A4 | -0.0606305 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0569393 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0553505 |
| RUNX2 | runt-related transcription factor 2 | -0.0506179 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0478435 |
| ZNF292 | zinc finger protein 292 | -0.0424453 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0423902 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0415055 |
| OGA | O-GlcNAcase | -0.0407659 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0402297 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0400044 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0394142 |
| USP3 | ubiquitin specific peptidase 3 | -0.0393369 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0392203 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0388781 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0370632 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0367049 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0366656 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0347905 |
| GPC6 | glypican 6 | -0.0344039 |
| PID1 | phosphotyrosine interaction domain containing 1 | -0.0340552 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0339335 |
| CD109 | CD109 molecule | -0.033838 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0336923 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0334318 |
| SRP54 | signal recognition particle 54kDa | -0.0329204 |
| COG5 | component of oligomeric golgi complex 5 | -0.0324871 |
| ARF4 | ADP-ribosylation factor 4 | -0.0324173 |
| PRELID2 | PRELI domain containing 2 | -0.0322979 |
| NRP1 | neuropilin 1 | -0.0320364 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.031688 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0315273 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0314782 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0310067 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0305123 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | -0.0304993 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0303195 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0296266 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0294738 |
| RNF145 | ring finger protein 145 | -0.029163 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0289098 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0287587 |
| ESCO1 | establishment of sister chromatid cohesion N-acetyltransferase 1 | -0.0284949 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | -0.0283081 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.028294 |
| ADD3 | adducin 3 (gamma) | -0.028117 |
| FBXL13 | F-box and leucine-rich repeat protein 13 | -0.0278386 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0270025 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0269084 |
| NBAS | neuroblastoma amplified sequence | -0.0267672 |
| FAM13A | family with sequence similarity 13, member A | -0.0265964 |
| SBF2 | SET binding factor 2 | -0.0265471 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0262096 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0261466 |
| AOPEP | aminopeptidase O (putative) | -0.0258362 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.02554 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0253785 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0253777 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0253773 |
| THOC2 | THO complex 2 | -0.025341 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0253199 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0252256 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0249316 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0246872 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.024687 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0245585 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0243841 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0240384 |
| FOXO3 | forkhead box O3 | -0.0239083 |
| CEP95 | centrosomal protein 95kDa | -0.0238374 |
| NF1 | neurofibromin 1 | -0.0237499 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0236771 |
| POM121 | POM121 transmembrane nucleoporin | -0.0236293 |
| LRRC49 | leucine rich repeat containing 49 | -0.0235689 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0234571 |
| POU2F1 | POU class 2 homeobox 1 | -0.0234312 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.0232032 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | -0.023143 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | -0.0224748 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0223363 |
| SETD5 | SET domain containing 5 | -0.0220376 |
| ATP13A3 | ATPase type 13A3 | -0.0219436 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0219289 |
| MORF4L2 | mortality factor 4 like 2 | -0.021911 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0216154 |
| GNAS | GNAS complex locus | -0.02149 |
| SS18 | synovial sarcoma translocation, chromosome 18 | -0.0213819 |
| AAK1 | AP2 associated kinase 1 | -0.0213668 |
| CFDP1 | craniofacial development protein 1 | -0.021297 |
| PTEN | phosphatase and tensin homolog | -0.0212555 |
| METTL15 | methyltransferase like 15 | -0.0211347 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0210367 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0209693 |
| ETV6 | ets variant 6 | -0.0209617 |
