| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | BAY1125976 perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the BAY1125976_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.203333 |
| LMO7 | LIM domain 7 | 0.161183 |
| EFNA5 | ephrin-A5 | 0.118258 |
| EGFR | epidermal growth factor receptor | 0.105724 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0999359 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0997847 |
| AREG | amphiregulin | 0.0947652 |
| MYO1E | myosin IE | 0.0943785 |
| RPL37A | ribosomal protein L37a | 0.0934712 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0925473 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.092383 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0914293 |
| SLC38A1 | solute carrier family 38, member 1 | 0.087068 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0868542 |
| FLNB | filamin B, beta | 0.0863598 |
| MT2A | metallothionein 2A | 0.0815373 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0797268 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0782044 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0771374 |
| SH3D19 | SH3 domain containing 19 | 0.0769367 |
| RPS3 | ribosomal protein S3 | 0.0748615 |
| ETV6 | ets variant 6 | 0.0741237 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0711882 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0690246 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0675637 |
| FAT1 | FAT atypical cadherin 1 | 0.0669803 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0657427 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0647999 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0638869 |
| DSPP | dentin sialophosphoprotein | 0.0632356 |
| EGR1 | early growth response 1 | 0.0625672 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0617593 |
| LAMC2 | laminin, gamma 2 | 0.0611641 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0607385 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0601716 |
| RPS29 | ribosomal protein S29 | 0.0596359 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0595981 |
| AHNAK | AHNAK nucleoprotein | 0.0592926 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0589864 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0587241 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0581559 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.057632 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0568662 |
| STC1 | stanniocalcin 1 | 0.0565047 |
| SLTM | SAFB-like, transcription modulator | 0.0549667 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0545941 |
| CREBBP | CREB binding protein | 0.0532852 |
| JUN | jun proto-oncogene | 0.0526108 |
| ANO6 | anoctamin 6 | 0.0519291 |
| APP | amyloid beta (A4) precursor protein | 0.0518601 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0508222 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0503151 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0498346 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.049679 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0496367 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.0496011 |
| SMAD2 | SMAD family member 2 | 0.0493994 |
| GOLGB1 | golgin B1 | 0.0482234 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0476537 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0470518 |
| CANX | calnexin | 0.0469795 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0469499 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0468318 |
| PLEC | plectin | 0.0467282 |
| PRKCSH | protein kinase C substrate 80K-H | 0.0462646 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0460638 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0458561 |
| RPLP0 | ribosomal protein, large, P0 | 0.045536 |
| PRKCA | protein kinase C, alpha | 0.0454457 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0449546 |
| SMAD3 | SMAD family member 3 | 0.0445779 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0440548 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0435683 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0434734 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0431397 |
| RPL13A | ribosomal protein L13a | 0.0425737 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0421248 |
| HDLBP | high density lipoprotein binding protein | 0.0420976 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0416453 |
| FTL | ferritin, light polypeptide | 0.0410992 |
| PKM | pyruvate kinase, muscle | 0.0404153 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0402935 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0396702 |
| GRB10 | growth factor receptor-bound protein 10 | 0.039194 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0389658 |
| RPS12 | ribosomal protein S12 | 0.0387397 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.038338 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0371209 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0367092 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0354988 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0352766 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0349027 |
| RPL37 | ribosomal protein L37 | 0.0341262 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.0336186 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0323853 |
| ASPH | aspartate beta-hydroxylase | 0.0318386 |
| SQSTM1 | sequestosome 1 | 0.0313887 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0313703 |
| PTMA | prothymosin, alpha | 0.0312397 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0311533 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.185848 |
| FN1 | fibronectin 1 | -0.141998 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.138732 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.133487 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.115998 |
| IGF2 | insulin-like growth factor 2 | -0.108097 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.0962253 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0948756 |
| SETD5 | SET domain containing 5 | -0.0852211 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0838475 |
| RTN4 | reticulon 4 | -0.0828431 |
| PDE10A | phosphodiesterase 10A | -0.0825784 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0818085 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0813223 |
| NF1 | neurofibromin 1 | -0.077827 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0740199 |
| LSAMP | limbic system-associated membrane protein | -0.0725476 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.072479 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0716117 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0715946 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0714952 |
| BPTF | bromodomain PHD finger transcription factor | -0.0700864 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0681842 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0673663 |
| RPL19 | ribosomal protein L19 | -0.0663847 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0655297 |
| JMJD1C | jumonji domain containing 1C | -0.0651187 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0646424 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0618147 |
| USP3 | ubiquitin specific peptidase 3 | -0.0617129 |
| FRMD4A | FERM domain containing 4A | -0.0614293 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.059887 |
| FOXO3 | forkhead box O3 | -0.0594554 |
| INHBA | inhibin, beta A | -0.0594484 |
| CLTC | clathrin, heavy chain (Hc) | -0.0594256 |
| HMGA2 | high mobility group AT-hook 2 | -0.0587779 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0562979 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0561817 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0551092 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0550824 |
| RNF213 | ring finger protein 213 | -0.0550584 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0547385 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0545765 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.053982 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0536722 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.0523672 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0506007 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0494567 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0486058 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0482219 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.04793 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0470652 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0470132 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0464913 |
| RLF | rearranged L-myc fusion | -0.0464476 |
| SRPK2 | SRSF protein kinase 2 | -0.0464179 |
| GPC6 | glypican 6 | -0.0462745 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0458536 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0450229 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0445654 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0441538 |
| SRSF4 | serine/arginine-rich splicing factor 4 | -0.0439721 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0434047 |
| VMP1 | vacuole membrane protein 1 | -0.0433966 |
| WASF2 | WAS protein family, member 2 | -0.043263 |
| RPS19 | ribosomal protein S19 | -0.0431494 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0422377 |
| NBAS | neuroblastoma amplified sequence | -0.0414128 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.041044 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.0400811 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0400239 |
| RNF216 | ring finger protein 216 | -0.0398408 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0397464 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0392317 |
| SIK3 | SIK family kinase 3 | -0.0389583 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0389504 |
| AFDN | afadin, adherens junction formation factor | -0.0387145 |
| OGA | O-GlcNAcase | -0.038281 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0369707 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.034647 |
| KIF13B | kinesin family member 13B | -0.0346155 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0346147 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0344823 |
| TASOR2 | transcription activation suppressor family member 2 | -0.0343556 |
| FUBP3 | far upstream element (FUSE) binding protein 3 | -0.0342634 |
| MACROD2 | MACRO domain containing 2 | -0.0342634 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | -0.0337797 |
| GOLGA4 | golgin A4 | -0.0337286 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.0329985 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0323253 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0320827 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0320565 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0312348 |
| SUCO | SUN domain containing ossification factor | -0.0304606 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0303067 |
| ELOVL5 | ELOVL fatty acid elongase 5 | -0.0302819 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0298518 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | -0.0294675 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0294168 |
| USP34 | ubiquitin specific peptidase 34 | -0.0293609 |
